메뉴 건너뛰기




Volumn 129, Issue 3, 2011, Pages 241-259

Single cell transcriptomics of hypothalamic warm sensitive neurons that control core body temperature and fever response: Signaling asymmetry and an extension of chemical neuroanatomy

Author keywords

Chemical neuroanatomy; Epigenetics; Microarray and sequencing; Transcriptome single cell; Warm sensitive neuron

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; ADIPONECTIN RECEPTOR 2; ADRENOMEDULLIN; CHEMOKINE; CYTOKINE; G PROTEIN COUPLED RECEPTOR; GALANIN; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 1; HETERODIMER; HORMONE RECEPTOR; INSULIN RECEPTOR; ION CHANNEL; MESSENGER RNA; NEUROTRANSMITTER; ORPHAN RECEPTOR; PRODYNORPHIN; RECEPTOR; SOMATOSTATIN; TACHYKININ; UNCLASSIFIED DRUG;

EID: 79551686317     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2010.09.010     Document Type: Review
Times cited : (73)

References (104)
  • 1
    • 0032078325 scopus 로고    scopus 로고
    • The interleukin-1 system: Receptors, ligands, and ICE in the brain and their involvement in the fever response
    • K. Alheim, and T. Bartfai The interleukin-1 system: receptors, ligands, and ICE in the brain and their involvement in the fever response Ann NY Acad Sci 840 1998 51 58
    • (1998) Ann NY Acad Sci , vol.840 , pp. 51-58
    • Alheim, K.1    Bartfai, T.2
  • 2
    • 0020002213 scopus 로고
    • Electrophysiological analysis of neuronal thermosensitivity in rat preoptic and hypothalamic tissue cultures
    • F. Baldino Jr., and H.M. Geller Electrophysiological analysis of neuronal thermosensitivity in rat preoptic and hypothalamic tissue cultures J Physiol 327 1982 173 184
    • (1982) J Physiol , vol.327 , pp. 173-184
    • Baldino Jr., F.1    Geller, H.M.2
  • 3
    • 0014936104 scopus 로고
    • Thermosensitivity of neurons in the sensorimotor cortex of the cat
    • J.L. Barker, and D.O. Carpenter Thermosensitivity of neurons in the sensorimotor cortex of the cat Science 169 945 1970 597 598
    • (1970) Science , vol.169 , Issue.945 , pp. 597-598
    • Barker, J.L.1    Carpenter, D.O.2
  • 6
    • 41149085493 scopus 로고    scopus 로고
    • Cytoplasmic BK(Ca) channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons
    • T.J. Bell, K.Y. Miyashiro, J.Y. Sul, R. McCullough, P.T. Buckley, and J. Jochems Cytoplasmic BK(Ca) channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons Proc Natl Acad Sci USA 105 6 2008 1901 1906
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.6 , pp. 1901-1906
    • Bell, T.J.1    Miyashiro, K.Y.2    Sul, J.Y.3    McCullough, R.4    Buckley, P.T.5    Jochems, J.6
  • 7
    • 0024412926 scopus 로고
    • Beta-adrenergic receptor kinase: Primary structure delineates a multigene family
    • J.L. Benovic, A. DeBlasi, W.C. Stone, M.G. Caron, and R.J. Lefkowitz Beta-adrenergic receptor kinase: primary structure delineates a multigene family Science 246 4927 1989 235 240
    • (1989) Science , vol.246 , Issue.4927 , pp. 235-240
    • Benovic, J.L.1    Deblasi, A.2    Stone, W.C.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 10
    • 0019843126 scopus 로고
    • Hypothalamic mechanisms in thermoregulation
    • J.A. Boulant Hypothalamic mechanisms in thermoregulation Fed Proc 40 14 1981 2843 2850
    • (1981) Fed Proc , vol.40 , Issue.14 , pp. 2843-2850
    • Boulant, J.A.1
  • 11
    • 0031799695 scopus 로고    scopus 로고
    • Cellular mechanisms of temperature sensitivity in hypothalamic neurons
    • J.A. Boulant Cellular mechanisms of temperature sensitivity in hypothalamic neurons Prog Brain Res 115 1998 3 8
    • (1998) Prog Brain Res , vol.115 , pp. 3-8
    • Boulant, J.A.1
  • 12
    • 0034456038 scopus 로고    scopus 로고
    • Role of the preoptic-anterior hypothalamus in thermoregulation and fever
    • J.A. Boulant Role of the preoptic-anterior hypothalamus in thermoregulation and fever Clin Infect Dis 31 Suppl 5 2000 S157 S161
    • (2000) Clin Infect Dis , vol.31 , Issue.SUPPL. 5
    • Boulant, J.A.1
  • 13
    • 33646374657 scopus 로고    scopus 로고
    • Neuronal basis of Hammel's model for set-point thermoregulation
    • J.A. Boulant Neuronal basis of Hammel's model for set-point thermoregulation J Appl Physiol 100 4 2006 1347 1354
    • (2006) J Appl Physiol , vol.100 , Issue.4 , pp. 1347-1354
    • Boulant, J.A.1
  • 14
    • 33749200360 scopus 로고    scopus 로고
    • Expression profiling of single mammalian cells-small is beautiful
    • G. Brady Expression profiling of single mammalian cells-small is beautiful Yeast 17 3 2000 211 217
    • (2000) Yeast , vol.17 , Issue.3 , pp. 211-217
    • Brady, G.1
  • 17
    • 0014107262 scopus 로고
    • Temperature effects on pacemaker generation, membrane potential, and critical firing threshold in Aplysia neurons
    • D.O. Carpenter Temperature effects on pacemaker generation, membrane potential, and critical firing threshold in Aplysia neurons J Gen Physiol 50 6 1967 1469 1484
    • (1967) J Gen Physiol , vol.50 , Issue.6 , pp. 1469-1484
    • Carpenter, D.O.1
  • 18
    • 33745642912 scopus 로고    scopus 로고
    • Cellular transcriptomics - The next phase of endocrine expression profiling
    • D. Carter Cellular transcriptomics-the next phase of endocrine expression profiling Trends Endocrinol Metab 17 5 2006 192 198
    • (2006) Trends Endocrinol Metab , vol.17 , Issue.5 , pp. 192-198
    • Carter, D.1
  • 20
    • 0032212633 scopus 로고    scopus 로고
    • Efferent projection from the preoptic area for the control of non-shivering thermogenesis in rats
    • X.M. Chen, T. Hosono, T. Yoda, Y. Fukuda, and K. Kanosue Efferent projection from the preoptic area for the control of non-shivering thermogenesis in rats J Physiol 512 Pt 3 1998 883 892
    • (1998) J Physiol , vol.512 , Issue.PART 3 , pp. 883-892
    • Chen, X.M.1    Hosono, T.2    Yoda, T.3    Fukuda, Y.4    Kanosue, K.5
  • 21
    • 0037229758 scopus 로고    scopus 로고
    • Analysis of energy expenditure at different ambient temperatures in mice lacking DGAT1
    • H.C. Chen, Z. Ladha, S.J. Smith, and R.V. Farese Jr. Analysis of energy expenditure at different ambient temperatures in mice lacking DGAT1 Am J Physiol Endocrinol Metab 284 1 2003 E213 E218
    • (2003) Am J Physiol Endocrinol Metab , vol.284 , Issue.1
    • Chen, H.C.1    Ladha, Z.2    Smith, S.J.3    Farese Jr., R.V.4
  • 22
    • 0004359411 scopus 로고
    • Hypothalamic regulation of body temperature
    • G. Clark, H.W. Magoun, and S.W. Ranson Hypothalamic regulation of body temperature J Neurophysiol 2 1 1939 61 80
    • (1939) J Neurophysiol , vol.2 , Issue.1 , pp. 61-80
    • Clark, G.1    Magoun, H.W.2    Ranson, S.W.3
  • 23
    • 0031593906 scopus 로고    scopus 로고
    • Prostaglandin E2 in the pathogenesis of fever An update
    • F. Coceani, and E.S. Akarsu Prostaglandin E2 in the pathogenesis of fever An update Ann NY Acad Sci 856 1998 76 82
    • (1998) Ann NY Acad Sci , vol.856 , pp. 76-82
    • Coceani, F.1    Akarsu, E.S.2
  • 24
    • 0028027290 scopus 로고
    • Impulse flow dependency of galanin release in vivo in the rat ventral hippocampus
    • S. Consolo, G. Baldi, G. Russi, G. Civenni, T. Bartfai, and A. Vezzani Impulse flow dependency of galanin release in vivo in the rat ventral hippocampus Proc Natl Acad Sci USA 91 17 1994 8047 8051
    • (1994) Proc Natl Acad Sci USA , vol.91 , Issue.17 , pp. 8047-8051
    • Consolo, S.1    Baldi, G.2    Russi, G.3    Civenni, G.4    Bartfai, T.5    Vezzani, A.6
  • 26
    • 70449220021 scopus 로고
    • Fluorescent antibody methods
    • A.H. Coons Fluorescent antibody methods Gen Cytochem Meth 1 1958 399 422
    • (1958) Gen Cytochem Meth , vol.1 , pp. 399-422
    • Coons, A.H.1
  • 27
    • 0013774096 scopus 로고
    • Localization of monoamines in the lower brain stem
    • A. Dahlstrom, and K. Fuxe Localization of monoamines in the lower brain stem Experientia 20 7 1964 398 399
    • (1964) Experientia , vol.20 , Issue.7 , pp. 398-399
    • Dahlstrom, A.1    Fuxe, K.2
  • 28
    • 33746927145 scopus 로고    scopus 로고
    • IL-1beta induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons
    • C.N. Davis, I. Tabarean, S. Gaidarova, M.M. Behrens, and T. Bartfai IL-1beta induces a MyD88-dependent and ceramide-mediated activation of Src in anterior hypothalamic neurons J Neurochem 98 5 2006 1379 1389
    • (2006) J Neurochem , vol.98 , Issue.5 , pp. 1379-1389
    • Davis, C.N.1    Tabarean, I.2    Gaidarova, S.3    Behrens, M.M.4    Bartfai, T.5
  • 29
    • 0024322255 scopus 로고
    • In vitro localization of thermosensitive neurons in the rat diencephalon
    • J.B. Dean, and J.A. Boulant In vitro localization of thermosensitive neurons in the rat diencephalon Am J Physiol 257 1 Pt 2 1989 R57 R64
    • (1989) Am J Physiol , vol.257 , Issue.1 PART 2
    • Dean, J.B.1    Boulant, J.A.2
  • 30
    • 0033377587 scopus 로고    scopus 로고
    • Cytokines as endogenous pyrogens
    • C.A. Dinarello Cytokines as endogenous pyrogens J Infect Dis 179 Suppl 2 1999 S294 S304
    • (1999) J Infect Dis , vol.179 , Issue.SUPPL. 2
    • Dinarello, C.A.1
  • 31
    • 8344261590 scopus 로고    scopus 로고
    • Infection, fever, and exogenous and endogenous pyrogens: Some concepts have changed
    • C.A. Dinarello Infection, fever, and exogenous and endogenous pyrogens: some concepts have changed J Endotoxin Res 10 4 2004 201 222
    • (2004) J Endotoxin Res , vol.10 , Issue.4 , pp. 201-222
    • Dinarello, C.A.1
  • 33
    • 0020075397 scopus 로고
    • Molecular basis of fever in humans
    • C.A. Dinarello, and S.M. Wolff Molecular basis of fever in humans Am J Med 72 5 1982 799 819
    • (1982) Am J Med , vol.72 , Issue.5 , pp. 799-819
    • Dinarello, C.A.1    Wolff, S.M.2
  • 34
    • 0032482954 scopus 로고    scopus 로고
    • The area code hypothesis revisited: Olfactory receptors and other related transmembrane receptors may function as the last digits in a cell surface code for assembling embryos
    • W.J. Dreyer The area code hypothesis revisited: olfactory receptors and other related transmembrane receptors may function as the last digits in a cell surface code for assembling embryos Proc Natl Acad Sci USA 95 16 1998 9072 9077
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.16 , pp. 9072-9077
    • Dreyer, W.J.1
  • 35
    • 79551681545 scopus 로고    scopus 로고
    • Dubbins J Hadcock J GPR83 in WSNs, KO and knockdown studies, Keystone Symposium
    • Dubbins J Hadcock J GPR83 in WSNs, KO and knockdown studies, Keystone Symposium,2010
    • (2010)
  • 36
    • 11144296834 scopus 로고    scopus 로고
    • Adaptive thermogenesis and uncoupling proteins: A reappraisal of their roles in fat metabolism and energy balance
    • A.G. Dulloo, J. Seydoux, and J. Jacquet Adaptive thermogenesis and uncoupling proteins: a reappraisal of their roles in fat metabolism and energy balance Physiol Behav 83 4 2004 587 602
    • (2004) Physiol Behav , vol.83 , Issue.4 , pp. 587-602
    • Dulloo, A.G.1    Seydoux, J.2    Jacquet, J.3
  • 38
    • 84941018758 scopus 로고
    • New evidence for the localization of noradrenalin in the adrenergic nerve terminals
    • B. Falck, and A. Torp New evidence for the localization of noradrenalin in the adrenergic nerve terminals Med Exp Int J Exp Med 6 1962 169 172
    • (1962) Med Exp Int J Exp Med , vol.6 , pp. 169-172
    • Falck, B.1    Torp, A.2
  • 39
    • 2942582908 scopus 로고    scopus 로고
    • Axon guidance of mouse olfactory sensory neurons by odorant receptors and the β2 adrenergic receptor
    • DOI 10.1016/j.cell.2004.05.013, PII S0092867404005318
    • P. Feinstein, T. Bozza, I. Rodriguez, A. Vassalli, and P. Mombaerts Axon guidance of mouse olfactory sensory neurons by odorant receptors and the beta2 adrenergic receptor Cell 117 6 2004 833 846 (Pubitemid 38748897)
    • (2004) Cell , vol.117 , Issue.6 , pp. 833-846
    • Feinstein, P.1    Bozza, T.2    Rodriguez, I.3    Vassalli, A.4    Mombaerts, P.5
  • 40
    • 0015187691 scopus 로고
    • Further studies on prostaglandin e 1 fever in cats
    • W. Feldberg, and P.N. Saxena Further studies on prostaglandin E 1 fever in cats J Physiol 219 3 1971 739 745
    • (1971) J Physiol , vol.219 , Issue.3 , pp. 739-745
    • Feldberg, W.1    Saxena, P.N.2
  • 41
    • 2442671756 scopus 로고    scopus 로고
    • Preoptic alpha 1- and alpha 2-noradrenergic agonists induce, respectively, PGE2-independent and PGE2-dependent hyperthermic responses in guinea pigs
    • C. Feleder, V. Perlik, and C.M. Blatteis Preoptic alpha 1- and alpha 2-noradrenergic agonists induce, respectively, PGE2-independent and PGE2-dependent hyperthermic responses in guinea pigs Am J Physiol Regul Integr Comp Physiol 286 6 2004 R1156 R1166
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286 , Issue.6
    • Feleder, C.1    Perlik, V.2    Blatteis, C.M.3
  • 42
    • 0242401835 scopus 로고    scopus 로고
    • A gene expression atlas of the central nervous system based on bacterial artificial chromosomes
    • S. Gong, C. Zheng, M.L. Doughty, K. Losos, N. Didkovsky, and U.B. Schambra A gene expression atlas of the central nervous system based on bacterial artificial chromosomes Nature 425 6961 2003 917 925
    • (2003) Nature , vol.425 , Issue.6961 , pp. 917-925
    • Gong, S.1    Zheng, C.2    Doughty, M.L.3    Losos, K.4    Didkovsky, N.5    Schambra, U.B.6
  • 44
    • 0029924012 scopus 로고    scopus 로고
    • Cellular mechanisms for neuronal thermosensitivity in the rat hypothalamus
    • J.D. Griffin, M.L. Kaple, A.R. Chow, and J.A. Boulant Cellular mechanisms for neuronal thermosensitivity in the rat hypothalamus J Physiol 492 Pt 1 1996 231 242
    • (1996) J Physiol , vol.492 , Issue.PART 1 , pp. 231-242
    • Griffin, J.D.1    Kaple, M.L.2    Chow, A.R.3    Boulant, J.A.4
  • 45
    • 0035576775 scopus 로고    scopus 로고
    • Synaptic and morphological characteristics of temperature-sensitive and -insensitive rat hypothalamic neurones
    • J.D. Griffin, C.B. Saper, and J.A. Boulant Synaptic and morphological characteristics of temperature-sensitive and -insensitive rat hypothalamic neurones J Physiol 537 Pt 2 2001 521 535
    • (2001) J Physiol , vol.537 , Issue.PART 2 , pp. 521-535
    • Griffin, J.D.1    Saper, C.B.2    Boulant, J.A.3
  • 46
    • 0002666413 scopus 로고
    • Neurons and temperature regulation
    • H.T. Hammel Neurons and temperature regulation W.S. Yamamoto, J.R. Brobeck, Physiological controls and regulations 1965 Saunders Philadelphia 71 97
    • (1965) Physiological Controls and Regulations , pp. 71-97
    • Hammel, H.T.1
  • 48
    • 76849116338 scopus 로고    scopus 로고
    • Looking at neurotransmitters in the microscope
    • T. Hokfelt Looking at neurotransmitters in the microscope Prog Neurobiol 90 2 2010 101 118
    • (2010) Prog Neurobiol , vol.90 , Issue.2 , pp. 101-118
    • Hokfelt, T.1
  • 49
    • 0023505467 scopus 로고
    • Localization of neuroactive substances in the hypothalamus with special reference to coexistence of messenger molecules
    • T. Hokfelt, Y. Tsuruo, B. Meister, T. Melander, M. Schalling, and B. Everitt Localization of neuroactive substances in the hypothalamus with special reference to coexistence of messenger molecules Adv Exp Med Biol 219 1987 21 45
    • (1987) Adv Exp Med Biol , vol.219 , pp. 21-45
    • Hokfelt, T.1    Tsuruo, Y.2    Meister, B.3    Melander, T.4    Schalling, M.5    Everitt, B.6
  • 50
    • 0021185689 scopus 로고
    • Effects of leukocytic pyrogen and sodium salicylate on hypothalamic thermosensitive neurons in vitro
    • T. Hori, T. Nakashima, T. Kiyohara, and M. Shibata Effects of leukocytic pyrogen and sodium salicylate on hypothalamic thermosensitive neurons in vitro Neurosci Lett 49 3 1984 313 318
    • (1984) Neurosci Lett , vol.49 , Issue.3 , pp. 313-318
    • Hori, T.1    Nakashima, T.2    Kiyohara, T.3    Shibata, M.4
  • 51
    • 0023871032 scopus 로고
    • Effects of interleukin-1 and arachidonate on the preoptic and anterior hypothalamic neurons
    • T. Hori, M. Shibata, T. Nakashima, M. Yamasaki, A. Asami, and T. Asami Effects of interleukin-1 and arachidonate on the preoptic and anterior hypothalamic neurons Brain Res Bull 20 1 1988 75 82
    • (1988) Brain Res Bull , vol.20 , Issue.1 , pp. 75-82
    • Hori, T.1    Shibata, M.2    Nakashima, T.3    Yamasaki, M.4    Asami, A.5    Asami, T.6
  • 52
    • 33749632376 scopus 로고    scopus 로고
    • Different expression patterns of TRP genes in murine B and T lymphocytes
    • H. Inada, T. Iida, and M. Tominaga Different expression patterns of TRP genes in murine B and T lymphocytes Biochem Biophys Res Commun 350 3 2006 762 767
    • (2006) Biochem Biophys Res Commun , vol.350 , Issue.3 , pp. 762-767
    • Inada, H.1    Iida, T.2    Tominaga, M.3
  • 53
    • 70350228331 scopus 로고    scopus 로고
    • The Allen Brain Atlas: 5 years and beyond
    • A.R. Jones, C.C. Overly, and S.M. Sunkin The Allen Brain Atlas: 5 years and beyond Nat Rev Neurosci 10 11 2009 821 828
    • (2009) Nat Rev Neurosci , vol.10 , Issue.11 , pp. 821-828
    • Jones, A.R.1    Overly, C.C.2    Sunkin, S.M.3
  • 54
    • 0041878279 scopus 로고    scopus 로고
    • Lessons from peppers and peppermint: The molecular logic of thermosensation
    • S.E. Jordt, D.D. McKemy, and D. Julius Lessons from peppers and peppermint: the molecular logic of thermosensation Curr Opin Neurobiol 13 4 2003 487 492
    • (2003) Curr Opin Neurobiol , vol.13 , Issue.4 , pp. 487-492
    • Jordt, S.E.1    McKemy, D.D.2    Julius, D.3
  • 55
    • 0033031426 scopus 로고    scopus 로고
    • Preparation of cDNA from single cells and subcellular regions
    • J.E. Kacharmina, P.B. Crino, and J. Eberwine Preparation of cDNA from single cells and subcellular regions Meth Enzymol 303 1999 3 18
    • (1999) Meth Enzymol , vol.303 , pp. 3-18
    • Kacharmina, J.E.1    Crino, P.B.2    Eberwine, J.3
  • 56
    • 0020211823 scopus 로고
    • Effect of synaptic blockade on thermosensitive neurons in hypothalamic tissue slices
    • S.R. Kelso, and J.A. Boulant Effect of synaptic blockade on thermosensitive neurons in hypothalamic tissue slices Am J Physiol 243 5 1982 R480 R490
    • (1982) Am J Physiol , vol.243 , Issue.5
    • Kelso, S.R.1    Boulant, J.A.2
  • 58
    • 77953535926 scopus 로고    scopus 로고
    • RNA: State memory and mediator of cellular phenotype
    • Kim, J., & Eberwine, J. RNA: state memory and mediator of cellular phenotype. Trends Cell Biol, 20(6): 311-8.
    • Trends Cell Biol , vol.20 , Issue.6 , pp. 311-318
    • Kim, J.1    Eberwine, J.2
  • 59
    • 0022005996 scopus 로고
    • GABAergic neurons containing CCK-8-like and/or VIP-like immunoreactivities in the rat hippocampus and dentate gyrus
    • T. Kosaka, K. Kosaka, K. Tateishi, Y. Hamaoka, N. Yanaihara, J.Y. Wu, and K. Hama GABAergic neurons containing CCK-8-like and/or VIP-like immunoreactivities in the rat hippocampus and dentate gyrus J Comp Neurol 239 1985 420 430
    • (1985) J Comp Neurol , vol.239 , pp. 420-430
    • Kosaka, T.1    Kosaka, K.2    Tateishi, K.3    Hamaoka, Y.4    Yanaihara, N.5    Wu, J.Y.6    Hama, K.7
  • 60
    • 0022856921 scopus 로고
    • Diet, obesity and hypertension: An hypothesis involving insulin, the sympathetic nervous system, and adaptive thermogenesis
    • L. Landsberg Diet, obesity and hypertension: an hypothesis involving insulin, the sympathetic nervous system, and adaptive thermogenesis Q J Med 61 236 1986 1081 1090
    • (1986) Q J Med , vol.61 , Issue.236 , pp. 1081-1090
    • Landsberg, L.1
  • 62
    • 34547953765 scopus 로고    scopus 로고
    • ThermoTRP channels as modular proteins with allosteric gating
    • R. Latorre, S. Brauchi, G. Orta, C. Zaelzer, and G. Vargas ThermoTRP channels as modular proteins with allosteric gating Cell Calcium 42 4-5 2007 427 438
    • (2007) Cell Calcium , vol.42 , Issue.45 , pp. 427-438
    • Latorre, R.1    Brauchi, S.2    Orta, G.3    Zaelzer, C.4    Vargas, G.5
  • 63
    • 33846252240 scopus 로고    scopus 로고
    • Genome-wide atlas of gene expression in the adult mouse brain
    • E.S. Lein, M.J. Hawrylycz, N. Ao, M. Ayres, A. Bensinger, and A. Bernard Genome-wide atlas of gene expression in the adult mouse brain Nature 445 7124 2007 168 176
    • (2007) Nature , vol.445 , Issue.7124 , pp. 168-176
    • Lein, E.S.1    Hawrylycz, M.J.2    Ao, N.3    Ayres, M.4    Bensinger, A.5    Bernard, A.6
  • 64
    • 70449428708 scopus 로고    scopus 로고
    • Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers
    • M.D. Levin, M.M. Lu, N.B. Petrenko, B.J. Hawkins, T.H. Gupta, and D. Lang Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers J Clin Investig 119 11 2009 3420 3436
    • (2009) J Clin Investig , vol.119 , Issue.11 , pp. 3420-3436
    • Levin, M.D.1    Lu, M.M.2    Petrenko, N.B.3    Hawkins, B.J.4    Gupta, T.H.5    Lang, D.6
  • 65
    • 0034611678 scopus 로고    scopus 로고
    • Towards a molecular understanding of adaptive thermogenesis
    • B.B. Lowell, and B.M. Spiegelman Towards a molecular understanding of adaptive thermogenesis Nature 404 6778 2000 652 660
    • (2000) Nature , vol.404 , Issue.6778 , pp. 652-660
    • Lowell, B.B.1    Spiegelman, B.M.2
  • 66
    • 60849113988 scopus 로고    scopus 로고
    • Analyzing the validity of GalR1 and GalR2 antibodies using knockout mice
    • X. Lu, and T. Bartfai Analyzing the validity of GalR1 and GalR2 antibodies using knockout mice Naunyn Schmiedebergs Arch Pharmacol 379 4 2009 417 420
    • (2009) Naunyn Schmiedebergs Arch Pharmacol , vol.379 , Issue.4 , pp. 417-420
    • Lu, X.1    Bartfai, T.2
  • 67
    • 2342607081 scopus 로고
    • Vasoactive intestinal polypeptide and cholinergic mechanisms in cat nasal mucosa: Studies on choline acetyltransferase and release of vasoactive intestinal polypeptide
    • J.M. Lundberg, A. Anggard, P. Emson, J. Fahrenkrug, and T. Hokfelt Vasoactive intestinal polypeptide and cholinergic mechanisms in cat nasal mucosa: studies on choline acetyltransferase and release of vasoactive intestinal polypeptide Proc Natl Acad Sci USA 78 8 1981 5255 5259
    • (1981) Proc Natl Acad Sci USA , vol.78 , Issue.8 , pp. 5255-5259
    • Lundberg, J.M.1    Anggard, A.2    Emson, P.3    Fahrenkrug, J.4    Hokfelt, T.5
  • 68
    • 20444371962 scopus 로고    scopus 로고
    • Important pharmacophores for binding to galanin receptor 2
    • L. Lundstrom, X. Lu, U. Langel, and T. Bartfai Important pharmacophores for binding to galanin receptor 2 Neuropeptides 39 3 2005 169 171
    • (2005) Neuropeptides , vol.39 , Issue.3 , pp. 169-171
    • Lundstrom, L.1    Lu, X.2    Langel, U.3    Bartfai, T.4
  • 69
    • 0027308854 scopus 로고
    • Body size, metabolic rate, generation time, and the molecular clock
    • A.P. Martin, and S.R. Palumbi Body size, metabolic rate, generation time, and the molecular clock Proc Natl Acad Sci USA 90 9 1993 4087 4091
    • (1993) Proc Natl Acad Sci USA , vol.90 , Issue.9 , pp. 4087-4091
    • Martin, A.P.1    Palumbi, S.R.2
  • 70
    • 72149118710 scopus 로고    scopus 로고
    • Perspective: Does brown fat protect against diseases of aging?
    • M.P. Mattson Perspective: Does brown fat protect against diseases of aging? Ageing Res Rev 9 1 2010 69 76
    • (2010) Ageing Res Rev , vol.9 , Issue.1 , pp. 69-76
    • Mattson, M.P.1
  • 71
    • 34250795146 scopus 로고    scopus 로고
    • Temperature sensing across species
    • D.D. McKemy Temperature sensing across species Pflugers Arch 454 5 2007 777 791
    • (2007) Pflugers Arch , vol.454 , Issue.5 , pp. 777-791
    • McKemy, D.D.1
  • 73
    • 45849151307 scopus 로고    scopus 로고
    • Galanin, galanin receptors and drug targets
    • K. Mitsukawa, X. Lu, and T. Bartfai Galanin, galanin receptors and drug targets Cell Mol Life Sci 65 12 2008 1796 1805
    • (2008) Cell Mol Life Sci , vol.65 , Issue.12 , pp. 1796-1805
    • Mitsukawa, K.1    Lu, X.2    Bartfai, T.3
  • 74
    • 62949114441 scopus 로고    scopus 로고
    • Subcellular neuropharmacology: The importance of intracellular targeting
    • K.Y. Miyashiro, T.J. Bell, J.Y. Sul, and J. Eberwine Subcellular neuropharmacology: the importance of intracellular targeting Trends Pharmacol Sci 30 2009 203 211
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 203-211
    • Miyashiro, K.Y.1    Bell, T.J.2    Sul, J.Y.3    Eberwine, J.4
  • 75
    • 0033367293 scopus 로고    scopus 로고
    • Genetics of chemotaxis and thermotaxis in the nematode Caenorhabditis elegans
    • I. Mori Genetics of chemotaxis and thermotaxis in the nematode Caenorhabditis elegans Annu Rev Genet 33 1999 399 422
    • (1999) Annu Rev Genet , vol.33 , pp. 399-422
    • Mori, I.1
  • 76
    • 58549090141 scopus 로고    scopus 로고
    • The direct excitatory effect of IL-1beta on cerebellar Purkinje cell
    • K. Motoki, H. Kishi, E. Hori, K. Tajiri, and H.M. Nishijo The direct excitatory effect of IL-1beta on cerebellar Purkinje cell Biochem Biophys Res Commun 13;379 3 2009 Feb 665 668
    • (2009) Biochem Biophys Res Commun , vol.133 , Issue.3 , pp. 665-668
    • Motoki, K.1    Kishi, H.2    Hori, E.3    Tajiri, K.4    Nishijo, H.M.5
  • 77
    • 0036615867 scopus 로고    scopus 로고
    • The rostral raphe pallidus nucleus mediates pyrogenic transmission from the preoptic area
    • K. Nakamura, K. Matsumura, T. Kaneko, S. Kobayashi, H. Katoh, and M. Negishi The rostral raphe pallidus nucleus mediates pyrogenic transmission from the preoptic area J Neurosci 22 11 2002 4600 4610
    • (2002) J Neurosci , vol.22 , Issue.11 , pp. 4600-4610
    • Nakamura, K.1    Matsumura, K.2    Kaneko, T.3    Kobayashi, S.4    Katoh, H.5    Negishi, M.6
  • 78
    • 37549014480 scopus 로고    scopus 로고
    • A thermosensory pathway that controls body temperature
    • K. Nakamura, and S.F. Morrison A thermosensory pathway that controls body temperature Nat Neurosci 11 1 2008 62 71
    • (2008) Nat Neurosci , vol.11 , Issue.1 , pp. 62-71
    • Nakamura, K.1    Morrison, S.F.2
  • 79
    • 29344451395 scopus 로고    scopus 로고
    • Direct pyrogenic input from prostaglandin EP3 receptor-expressing preoptic neurons to the dorsomedial hypothalamus
    • Y. Nakamura, K. Nakamura, K. Matsumura, S. Kobayashi, T. Kaneko, and S.F. Morrison Direct pyrogenic input from prostaglandin EP3 receptor-expressing preoptic neurons to the dorsomedial hypothalamus Eur J Neurosci 22 12 2005 3137 3146
    • (2005) Eur J Neurosci , vol.22 , Issue.12 , pp. 3137-3146
    • Nakamura, Y.1    Nakamura, K.2    Matsumura, K.3    Kobayashi, S.4    Kaneko, T.5    Morrison, S.F.6
  • 80
    • 0000295389 scopus 로고
    • Single unit activity of anterior hypothalamus during local heating
    • T. Nakayama, J.S. Eisenman, and J.D. Hardy Single unit activity of anterior hypothalamus during local heating Science 134 1961 560 561
    • (1961) Science , vol.134 , pp. 560-561
    • Nakayama, T.1    Eisenman, J.S.2    Hardy, J.D.3
  • 81
    • 0000292417 scopus 로고
    • Thermal stimulation of electrical activity of single units of preoptic region
    • T. Nakayama, H.T. Hammel, J.D. Hardy, and J.S. Eisenman Thermal stimulation of electrical activity of single units of preoptic region Am J Physiol 204 6 1963 1122
    • (1963) Am J Physiol , vol.204 , Issue.6 , pp. 1122
    • Nakayama, T.1    Hammel, H.T.2    Hardy, J.D.3    Eisenman, J.S.4
  • 82
    • 34547631960 scopus 로고    scopus 로고
    • Unexpected evidence for active brown adipose tissue in adult humans
    • J. Nedergaard, T. Bengtsson, and B. Cannon Unexpected evidence for active brown adipose tissue in adult humans Am J Physiol Endocrinol Metab 293 2 2007 E444 E452
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , Issue.2
    • Nedergaard, J.1    Bengtsson, T.2    Cannon, B.3
  • 83
    • 0019829496 scopus 로고
    • Intracellular recordings from thermosensitive preoptic neurons
    • D.O. Nelson, and C.L. Prosser Intracellular recordings from thermosensitive preoptic neurons Science 213 4509 1981 787 789
    • (1981) Science , vol.213 , Issue.4509 , pp. 787-789
    • Nelson, D.O.1    Prosser, C.L.2
  • 86
    • 0030560897 scopus 로고    scopus 로고
    • Antisense RNA amplification: A linear amplification method for analyzing the mRNA population from single living cells
    • J. Phillips, and J.H. Eberwine Antisense RNA amplification: a linear amplification method for analyzing the mRNA population from single living cells Methods 10 3 1996 283 288
    • (1996) Methods , vol.10 , Issue.3 , pp. 283-288
    • Phillips, J.1    Eberwine, J.H.2
  • 87
    • 48149103878 scopus 로고    scopus 로고
    • Bidirectional temperature-sensing by a single thermosensory neuron in C. elegans
    • D. Ramot, B.L. MacInnis, and M.B. Goodman Bidirectional temperature-sensing by a single thermosensory neuron in C. elegans Nat Neurosci 11 8 2008 908 915
    • (2008) Nat Neurosci , vol.11 , Issue.8 , pp. 908-915
    • Ramot, D.1    MacInnis, B.L.2    Goodman, M.B.3
  • 89
    • 0028782669 scopus 로고
    • The neurologic basis of fever
    • C.B. Saper, and C.D. Breder The neurologic basis of fever N Engl J Med 330 26 1994 1880 1886
    • (1994) N Engl J Med , vol.330 , Issue.26 , pp. 1880-1886
    • Saper, C.B.1    Breder, C.D.2
  • 90
    • 0347596696 scopus 로고    scopus 로고
    • The CMK-1 CaMKI and the TAX-4 Cyclic nucleotide-gated channel regulate thermosensory neuron gene expression and function in C. elegans
    • J.S. Satterlee, W.S. Ryu, and P. Sengupta The CMK-1 CaMKI and the TAX-4 Cyclic nucleotide-gated channel regulate thermosensory neuron gene expression and function in C. elegans Curr Biol 14 1 2004 62 68
    • (2004) Curr Biol , vol.14 , Issue.1 , pp. 62-68
    • Satterlee, J.S.1    Ryu, W.S.2    Sengupta, P.3
  • 91
    • 0020427480 scopus 로고
    • Coexistence of classical transmitters and peptides in the central and peripheral nervous systems
    • M. Schultzberg, T. Hokfelt, and J.M. Lundberg Coexistence of classical transmitters and peptides in the central and peripheral nervous systems Br Med Bull 38 3 1982 309 313
    • (1982) Br Med Bull , vol.38 , Issue.3 , pp. 309-313
    • Schultzberg, M.1    Hokfelt, T.2    Lundberg, J.M.3
  • 92
    • 0026333367 scopus 로고
    • Differential effects of cytokines on thermosensitive neurons in guinea pig preoptic area slices
    • M. Shibata, and C.M. Blatteis Differential effects of cytokines on thermosensitive neurons in guinea pig preoptic area slices Am J Physiol 261 5 Pt 2 1991 R1096 R1103
    • (1991) Am J Physiol , vol.261 , Issue.5 PART 2
    • Shibata, M.1    Blatteis, C.M.2
  • 93
    • 43549087397 scopus 로고    scopus 로고
    • Pharmacological profile of somatostatin and cortistatin receptors
    • S. Siehler, C. Nunn, J. Hannon, D. Feuerbach, and D. Hoyer Pharmacological profile of somatostatin and cortistatin receptors Mol Cell Endocrinol 286 1-2 2008 26 34
    • (2008) Mol Cell Endocrinol , vol.286 , Issue.12 , pp. 26-34
    • Siehler, S.1    Nunn, C.2    Hannon, J.3    Feuerbach, D.4    Hoyer, D.5
  • 94
    • 34648836391 scopus 로고    scopus 로고
    • Why 37 degrees C? Evolutionary fundamentals of thermoregulation
    • D. Singer Why 37 degrees C? Evolutionary fundamentals of thermoregulation Anaesthesist 56 9 2007 899 902 4 - 6.
    • (2007) Anaesthesist , vol.56 , Issue.9 , pp. 899-902
    • Singer, D.1
  • 96
    • 1442354843 scopus 로고    scopus 로고
    • Prostaglandin E2-increased thermosensitivity of anterior hypothalamic neurons is associated with depressed inhibition
    • I.V. Tabarean, M.M. Behrens, T. Bartfai, and H. Korn Prostaglandin E2-increased thermosensitivity of anterior hypothalamic neurons is associated with depressed inhibition Proc Natl Acad Sci USA 101 8 2004 2590 2595
    • (2004) Proc Natl Acad Sci USA , vol.101 , Issue.8 , pp. 2590-2595
    • Tabarean, I.V.1    Behrens, M.M.2    Bartfai, T.3    Korn, H.4
  • 97
    • 24944504440 scopus 로고    scopus 로고
    • Electrophysiological properties and thermosensitivity of mouse preoptic and anterior hypothalamic neurons in culture
    • I.V. Tabarean, B. Conti, M. Behrens, H. Korn, and T. Bartfai Electrophysiological properties and thermosensitivity of mouse preoptic and anterior hypothalamic neurons in culture Neuroscience 135 2 2005 433 449
    • (2005) Neuroscience , vol.135 , Issue.2 , pp. 433-449
    • Tabarean, I.V.1    Conti, B.2    Behrens, M.3    Korn, H.4    Bartfai, T.5
  • 98
    • 33747175900 scopus 로고    scopus 로고
    • Interleukin-1beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons
    • I.V. Tabarean, H. Korn, and T. Bartfai Interleukin-1beta induces hyperpolarization and modulates synaptic inhibition in preoptic and anterior hypothalamic neurons Neuroscience 141 4 2006 1685 1695
    • (2006) Neuroscience , vol.141 , Issue.4 , pp. 1685-1695
    • Tabarean, I.V.1    Korn, H.2    Bartfai, T.3
  • 99
    • 79551685537 scopus 로고
    • The Cartwright Lectures New York, NY
    • C.C. Welch Fever 1888 The Cartwright Lectures New York, NY
    • (1888) Fever
    • Welch, C.C.1
  • 100
    • 27744573039 scopus 로고    scopus 로고
    • Olfactory inputs to hypothalamic neurons controlling reproduction and fertility
    • H. Yoon, L.W. Enquist, and C. Dulac Olfactory inputs to hypothalamic neurons controlling reproduction and fertility Cell 123 4 2005 669 682
    • (2005) Cell , vol.123 , Issue.4 , pp. 669-682
    • Yoon, H.1    Enquist, L.W.2    Dulac, C.3
  • 101
    • 57349170697 scopus 로고    scopus 로고
    • Oxytocin and vasopressin gene expression and RNA splicing patterns in the rat supraoptic nucleus
    • C. Yue, T.A. Ponzio, R.L. Fields, and H. Gainer Oxytocin and vasopressin gene expression and RNA splicing patterns in the rat supraoptic nucleus Physiol Genomics 35 3 2008 231 242
    • (2008) Physiol Genomics , vol.35 , Issue.3 , pp. 231-242
    • Yue, C.1    Ponzio, T.A.2    Fields, R.L.3    Gainer, H.4
  • 102
    • 0029042605 scopus 로고
    • Warm and cold signals from the preoptic area: Which contribute more to the control of shivering in rats?
    • Y.H. Zhang, M. Yanase-Fujiwara, T. Hosono, and K. Kanosue Warm and cold signals from the preoptic area: which contribute more to the control of shivering in rats? J Physiol 485 Pt 1 1995 195 202
    • (1995) J Physiol , vol.485 , Issue.PART 1 , pp. 195-202
    • Zhang, Y.H.1    Yanase-Fujiwara, M.2    Hosono, T.3    Kanosue, K.4
  • 103
    • 17444363039 scopus 로고    scopus 로고
    • Temperature effects on neuronal membrane potentials and inward currents in rat hypothalamic tissue slices
    • Y. Zhao, and J.A. Boulant Temperature effects on neuronal membrane potentials and inward currents in rat hypothalamic tissue slices J Physiol 564 Pt 1 2005 245 257
    • (2005) J Physiol , vol.564 , Issue.PART 1 , pp. 245-257
    • Zhao, Y.1    Boulant, J.A.2
  • 104
    • 70349334680 scopus 로고    scopus 로고
    • The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue
    • M.C. Zingaretti, F. Crosta, A. Vitali, M. Guerrieri, A. Frontini, and B. Cannon The presence of UCP1 demonstrates that metabolically active adipose tissue in the neck of adult humans truly represents brown adipose tissue FASEB J 23 9 2009 3113 3120
    • (2009) FASEB J , vol.23 , Issue.9 , pp. 3113-3120
    • Zingaretti, M.C.1    Crosta, F.2    Vitali, A.3    Guerrieri, M.4    Frontini, A.5    Cannon, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.