-
1
-
-
17144474314
-
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
-
Ferrando AA, Neuberg DS, Staunton J, et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 2002;1:75-87.
-
(2002)
Cancer Cell
, vol.1
, pp. 75-87
-
-
Ferrando, A.A.1
Neuberg, D.S.2
Staunton, J.3
-
2
-
-
42649124306
-
Molecular pathogenesis of T-cell leukaemia and lymphoma
-
Aifantis I, Raetz E, Buonamici S. Molecular pathogenesis of T-cell leukaemia and lymphoma. Nat Rev Immunol 2008; 8:380-390.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 380-390
-
-
Aifantis, I.1
Raetz, E.2
Buonamici, S.3
-
4
-
-
0142180052
-
Gfi-1 oncoproteins in hematopoiesis
-
Duan Z, Horwitz M. Gfi-1 oncoproteins in hematopoiesis. Hematology 2003;8:339-344.
-
(2003)
Hematology
, vol.8
, pp. 339-344
-
-
Duan, Z.1
Horwitz, M.2
-
5
-
-
0037371433
-
Growth factor independence- 1B expression leads to defects in T cell activation IL-7 receptor alpha expression and T cell lineage commitment
-
Doan LL, Kitay MK, Yu Q, et al. Growth factor independence- 1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment. J Immunol 2003;170:2356-2366.
-
(2003)
J. Immunol.
, vol.170
, pp. 2356-2366
-
-
Doan, L.L.1
Kitay, M.K.2
Yu, Q.3
-
6
-
-
2942579675
-
TAL1/ SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB
-
O'Neil J, Shank J, Cusson N, Murre C, Kelliher M. TAL1/ SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB. Cancer Cell 2004;5:587-596.
-
(2004)
Cancer Cell
, vol.5
, pp. 587-596
-
-
O'Neil, J.1
Shank, J.2
Cusson, N.3
Murre, C.4
Kelliher, M.5
-
7
-
-
35349002806
-
Overexpression of a transcription factor LYL1 induces tand B-cell lymphoma in mice
-
Zhong Y, Jiang L, Hiai H, Toyokuni S, Yamada Y. Overexpression of a transcription factor LYL1 induces Tand B-cell lymphoma in mice. Oncogene 2007;26:6937-6947.
-
(2007)
Oncogene
, vol.26
, pp. 6937-6947
-
-
Zhong, Y.1
Jiang, L.2
Hiai, H.3
Toyokuni, S.4
Yamada, Y.5
-
8
-
-
0030752361
-
E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas
-
Bain G, Engel I, Robanus Maandag EC, et al. E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol Cell Biol 1997;17:4782-4791.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 4782-4791
-
-
Bain, G.1
Engel, I.2
Robanus Maandag, E.C.3
-
9
-
-
4043133786
-
Stat5 is required for thymopoiesis in a development stage-specific manner
-
Kang J, DiBenedetto B, Narayan K, Zhao H, Der SD, Chambers CA. STAT5 is required for thymopoiesis in a development stage-specific manner. J Immunol 2004;173: 2307-2314.
-
(2004)
J. Immunol.
, vol.173
, pp. 2307-2314
-
-
Kang, J.1
DiBenedetto, B.2
Narayan, K.3
Zhao, H.4
Der, S.D.5
Chambers, C.A.6
-
10
-
-
0141482125
-
The ardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t 5;14 q35.1;q32.2
-
Nagel S, Kaufmann M, Drexler HG, MacLeod RA. The ardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35.1;q32.2). Cancer Res 2003;63:5329-5334.
-
(2003)
Cancer Res.
, vol.63
, pp. 5329-5334
-
-
Nagel, S.1
Kaufmann, M.2
Drexler, H.G.3
MacLeod, R.A.4
-
11
-
-
22044457152
-
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia T-ALL
-
Soulier J, Clappier E, Cayuela JM, et al. HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL). Blood 2005;106:274-286.
-
(2005)
Blood
, vol.106
, pp. 274-286
-
-
Soulier, J.1
Clappier, E.2
Cayuela, J.M.3
-
12
-
-
40749115609
-
MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines
-
Nagel S, Meyer C, Quentmeier H, Kaufmann M, Drexler HG, MacLeod RA. MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines. Leukemia 2008;22:600-607.
-
(2008)
Leukemia
, vol.22
, pp. 600-607
-
-
Nagel, S.1
Meyer, C.2
Quentmeier, H.3
Kaufmann, M.4
Drexler, H.G.5
MacLeod, R.A.6
-
13
-
-
0345647074
-
Characterization of myocyte enhancer factor 2 MEF2 expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes
-
Swanson BJ, Jäck HM, Lyons GE. Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes. Mol Immunol 1998;35:445-458.
-
(1998)
Mol. Immunol.
, vol.35
, pp. 445-458
-
-
Swanson, B.J.1
Jäck, H.M.2
Lyons, G.E.3
-
14
-
-
44049105823
-
Transcription factor mef2c is required forbcell proliferation and survival after antigen receptor stimulation
-
Wilker PR,KohyamaM, SandauMM, et al.Transcription factor Mef2c is required forBcell proliferation and survival after antigen receptor stimulation. Nat Immunol 2008;9:603-612.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 603-612
-
-
Wilker, P.R.1
Kohyama, M.2
Sandau, M.M.3
-
15
-
-
60749111430
-
Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c
-
Stehling-Sun S, Dade J, Nutt SL, DeKoter RP, Camargo FD. Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c. Nat Immunol 2009;10:289-296.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 289-296
-
-
Stehling-Sun, S.1
Dade, J.2
Nutt, S.L.3
DeKoter, R.P.4
Camargo, F.D.5
-
16
-
-
70350495169
-
Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C
-
Schwieger M, Schü ler A, Forster M, et al. Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C. Blood 2009;114:2476-2488.
-
(2009)
Blood
, vol.114
, pp. 2476-2488
-
-
Schwieger, M.1
Schüler, A.2
Forster, M.3
-
17
-
-
64049095814
-
HOXA9 is required for survival in human MLL-rearranged acute leukemias
-
Faber J, Krivtsov AV, Stubbs MC, et al. HOXA9 is required for survival in human MLL-rearranged acute leukemias. Blood 2009;113:2375-2385.
-
(2009)
Blood
, vol.113
, pp. 2375-2385
-
-
Faber, J.1
Krivtsov, A.V.2
Stubbs, M.C.3
-
19
-
-
75649149337
-
Modeling the functional heterogeneity of leukemia stem cells: Role of STAT5 in leukemia stem cell self-renewal
-
Heuser M, Sly LM, Argiropoulos B, et al. Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal. Blood 2009;114: 3983-3993.
-
(2009)
Blood
, vol.114
, pp. 3983-3993
-
-
Heuser, M.1
Sly, L.M.2
Argiropoulos, B.3
-
20
-
-
0141611749
-
Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA
-
Scherr M, Battmer K, Ganser A, Eder M. Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA. Cell Cycle 2003;2:251-257.
-
(2003)
Cell Cycle.
, vol.2
, pp. 251-257
-
-
Scherr, M.1
Battmer, K.2
Ganser, A.3
Eder, M.4
-
21
-
-
0037450634
-
STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta
-
Xu M, Nie L, Kim SH, Sun XH. STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta. EMBO J 2003;22:893-904.
-
(2003)
EMBO J.
, vol.22
, pp. 893-904
-
-
Xu, M.1
Nie, L.2
Kim, S.H.3
Sun, X.H.4
-
22
-
-
33847793796
-
Activation of TLX3 and NKX2-5 in t 5;14 q35;q32 T-cell acute lymphoblastic leukemia by remote 30-BCL11B enhancers and coregulation by PU.1 and hmga1
-
Nagel S, Scherr M, Kel A, et al. Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 30-BCL11B enhancers and coregulation by PU.1 and HMGA1. Cancer Res 2007;67:1461-1471.
-
(2007)
Cancer Res.
, vol.67
, pp. 1461-1471
-
-
Nagel, S.1
Scherr, M.2
Kel, A.3
-
23
-
-
77449136887
-
High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription
-
Laurent B, Randrianarison-Huetz V, Marchal V, Mayeux P, Dusanter-Fourt I, Duménil D. High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription. Blood 2010;115:687-695.
-
(2010)
Blood
, Issue.115
, pp. 687-695
-
-
Laurent, B.1
Randrianarison-Huetz, V.2
Marchal, V.3
Mayeux, P.4
Dusanter-Fourt, I.5
Duménil, D.6
-
24
-
-
28844442337
-
Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9
-
Kawagoe H, Grosveld GC. Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9. Blood 2005;106:4269-4277.
-
(2005)
Blood
, vol.106
, pp. 4269-4277
-
-
Kawagoe, H.1
Grosveld, G.C.2
-
25
-
-
77949423437
-
Functional characterization of high levels of meningioma 1 as collaborating oncogene in acute leukemia
-
Liu T, Jankovic D, Brault L, et al. Functional characterization of high levels of meningioma 1 as collaborating oncogene in acute leukemia. Leukemia 2010;24:601-612.
-
(2010)
Leukemia
, Issue.24
, pp. 601-612
-
-
Liu, T.1
Jankovic, D.2
Brault, L.3
-
26
-
-
34347213447
-
Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation
-
Slape C, Hartung H, Lin YW, Bies J, Wolff L, Aplan PD. Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation. Cancer Res 2007;67:5148-5155.
-
(2007)
Cancer Res.
, vol.67
, pp. 5148-5155
-
-
Slape, C.1
Hartung, H.2
Lin, Y.W.3
Bies, J.4
Wolff, L.5
Aplan, P.D.6
-
27
-
-
0029892570
-
Isolation and characterization of nmi a novel partner of myc proteins
-
Bao J, Zervos AS. Isolation and characterization of Nmi, a novel partner of Myc proteins. Oncogene 1996;12:2171-2176.
-
(1996)
Oncogene.
, vol.12
, pp. 2171-2176
-
-
Bao, J.1
Zervos, A.S.2
-
28
-
-
0033534562
-
Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgammamediated signaling
-
Zhu M, John S, Berg M, Leonard WJ. Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgammamediated signaling. Cell 1999;96:121-130.
-
(1999)
Cell
, vol.96
, pp. 121-130
-
-
Zhu, M.1
John, S.2
Berg, M.3
Leonard, W.J.4
-
29
-
-
43049118632
-
A crucial role of a high mobility group protein HMGA2 in cardiogenesis
-
DOI 10.1038/ncb1719, PII NCB1719
-
Monzen K, Ito Y, Naito AT, et al. A crucial role of a high mobility group protein HMGA2 in cardiogenesis. Nat Cell Biol 2008;10:567-574. (Pubitemid 351627376)
-
(2008)
Nature Cell Biology
, vol.10
, Issue.5
, pp. 567-574
-
-
Monzen, K.1
Ito, Y.2
Naito, A.T.3
Kasai, H.4
Hiroi, Y.5
Hayashi, D.6
Shiojima, I.7
Yamazaki, T.8
Miyazono, K.9
Asashima, M.10
Nagai, R.11
Komuro, I.12
-
30
-
-
0033136288
-
Distinct roles of the phosphatidylinositol 3-kinase and stat5 pathways in il-7-mediated development of human thymocyte precursors
-
Pallard C, Stegmann AP, van Kleffens T, Smart F, Venkitaraman A, Spits H. Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 1999;10:525-535.
-
(1999)
Immunity
, vol.10
, pp. 525-535
-
-
Pallard, C.1
Stegmann, A.P.2
Van Kleffens, T.3
Smart, F.4
Venkitaraman, A.5
Spits, H.6
-
31
-
-
20444365877
-
Restricted stat5 activation dictates appropriate thymic b versus t cell lineage commitment
-
Goetz CA, Harmon IR, O'Neil JJ, Burchill MA, Johanns TM, Farrar MA. Restricted STAT5 activation dictates appropriate thymic B versus T cell lineage commitment. J Immunol 2005;174:7753-7763.
-
(2005)
J. Immunol.
, vol.174
, pp. 7753-7763
-
-
Goetz, C.A.1
Harmon, I.R.2
O'Neil, J.J.3
Burchill, M.A.4
Johanns, T.M.5
Farrar, M.A.6
-
32
-
-
77049121268
-
Multiple mechanisms induce ectopic expression of LYL1 in subsets of T-ALL cell lines
-
Nagel S, Venturini L, Meyer C, et al. Multiple mechanisms induce ectopic expression of LYL1 in subsets of T-ALL cell lines. Leuk Res 2010;34:521-528.
-
(2010)
Leuk. Res.
, Issue.34
, pp. 521-528
-
-
Nagel, S.1
Venturini, L.2
Meyer, C.3
-
34
-
-
65149100673
-
Mef2C is a lineagerestricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis
-
Gekas C, Rhodes KE, Gereige LM, et al. Mef2C is a lineagerestricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. Blood 2009;113:3461-3471.
-
(2009)
Blood
, vol.113
, pp. 3461-3471
-
-
Gekas, C.1
Rhodes, K.E.2
Gereige, L.M.3
-
35
-
-
0035203948
-
The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development
-
Wang DZ, Valdez MR, McAnally J, Richardson J, Olson EN. The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development. Development 2001;128:4623-4633.
-
(2001)
Development
, vol.128
, pp. 4623-4633
-
-
Wang, D.Z.1
Valdez, M.R.2
McAnally, J.3
Richardson, J.4
Olson, E.N.5
|