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Volumn 52, Issue 2, 2011, Pages 290-297

Transcriptional deregulation of oncogenic myocyte enhancer factor 2C in T-cell acute lymphoblastic leukemia

Author keywords

GFI1B; HOXA10; IL7; NMYC; STAT5

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; INTERLEUKIN 7; JANUS KINASE; STAT5 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GFI1B; TRANSCRIPTION FACTOR HOXA10; TRANSCRIPTION FACTOR HOXA9; TRANSCRIPTION FACTOR LYL1; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTRO MYOCYTE ENHANCER FACTOR 2C; UNCLASSIFIED DRUG;

EID: 79551627395     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.3109/10428194.2010.537003     Document Type: Article
Times cited : (24)

References (35)
  • 1
    • 17144474314 scopus 로고    scopus 로고
    • Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia
    • Ferrando AA, Neuberg DS, Staunton J, et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 2002;1:75-87.
    • (2002) Cancer Cell , vol.1 , pp. 75-87
    • Ferrando, A.A.1    Neuberg, D.S.2    Staunton, J.3
  • 2
    • 42649124306 scopus 로고    scopus 로고
    • Molecular pathogenesis of T-cell leukaemia and lymphoma
    • Aifantis I, Raetz E, Buonamici S. Molecular pathogenesis of T-cell leukaemia and lymphoma. Nat Rev Immunol 2008; 8:380-390.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 380-390
    • Aifantis, I.1    Raetz, E.2    Buonamici, S.3
  • 4
    • 0142180052 scopus 로고    scopus 로고
    • Gfi-1 oncoproteins in hematopoiesis
    • Duan Z, Horwitz M. Gfi-1 oncoproteins in hematopoiesis. Hematology 2003;8:339-344.
    • (2003) Hematology , vol.8 , pp. 339-344
    • Duan, Z.1    Horwitz, M.2
  • 5
    • 0037371433 scopus 로고    scopus 로고
    • Growth factor independence- 1B expression leads to defects in T cell activation IL-7 receptor alpha expression and T cell lineage commitment
    • Doan LL, Kitay MK, Yu Q, et al. Growth factor independence- 1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment. J Immunol 2003;170:2356-2366.
    • (2003) J. Immunol. , vol.170 , pp. 2356-2366
    • Doan, L.L.1    Kitay, M.K.2    Yu, Q.3
  • 6
    • 2942579675 scopus 로고    scopus 로고
    • TAL1/ SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB
    • O'Neil J, Shank J, Cusson N, Murre C, Kelliher M. TAL1/ SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB. Cancer Cell 2004;5:587-596.
    • (2004) Cancer Cell , vol.5 , pp. 587-596
    • O'Neil, J.1    Shank, J.2    Cusson, N.3    Murre, C.4    Kelliher, M.5
  • 7
    • 35349002806 scopus 로고    scopus 로고
    • Overexpression of a transcription factor LYL1 induces tand B-cell lymphoma in mice
    • Zhong Y, Jiang L, Hiai H, Toyokuni S, Yamada Y. Overexpression of a transcription factor LYL1 induces Tand B-cell lymphoma in mice. Oncogene 2007;26:6937-6947.
    • (2007) Oncogene , vol.26 , pp. 6937-6947
    • Zhong, Y.1    Jiang, L.2    Hiai, H.3    Toyokuni, S.4    Yamada, Y.5
  • 8
    • 0030752361 scopus 로고    scopus 로고
    • E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas
    • Bain G, Engel I, Robanus Maandag EC, et al. E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas. Mol Cell Biol 1997;17:4782-4791.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 4782-4791
    • Bain, G.1    Engel, I.2    Robanus Maandag, E.C.3
  • 10
    • 0141482125 scopus 로고    scopus 로고
    • The ardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t 5;14 q35.1;q32.2
    • Nagel S, Kaufmann M, Drexler HG, MacLeod RA. The ardiac homeobox gene NKX2-5 is deregulated by juxtaposition with BCL11B in pediatric T-ALL cell lines via a novel t(5;14)(q35.1;q32.2). Cancer Res 2003;63:5329-5334.
    • (2003) Cancer Res. , vol.63 , pp. 5329-5334
    • Nagel, S.1    Kaufmann, M.2    Drexler, H.G.3    MacLeod, R.A.4
  • 11
    • 22044457152 scopus 로고    scopus 로고
    • HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia T-ALL
    • Soulier J, Clappier E, Cayuela JM, et al. HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL). Blood 2005;106:274-286.
    • (2005) Blood , vol.106 , pp. 274-286
    • Soulier, J.1    Clappier, E.2    Cayuela, J.M.3
  • 12
    • 40749115609 scopus 로고    scopus 로고
    • MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines
    • Nagel S, Meyer C, Quentmeier H, Kaufmann M, Drexler HG, MacLeod RA. MEF2C is activated by multiple mechanisms in a subset of T-acute lymphoblastic leukemia cell lines. Leukemia 2008;22:600-607.
    • (2008) Leukemia , vol.22 , pp. 600-607
    • Nagel, S.1    Meyer, C.2    Quentmeier, H.3    Kaufmann, M.4    Drexler, H.G.5    MacLeod, R.A.6
  • 13
    • 0345647074 scopus 로고    scopus 로고
    • Characterization of myocyte enhancer factor 2 MEF2 expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes
    • Swanson BJ, Jäck HM, Lyons GE. Characterization of myocyte enhancer factor 2 (MEF2) expression in B and T cells: MEF2C is a B cell-restricted transcription factor in lymphocytes. Mol Immunol 1998;35:445-458.
    • (1998) Mol. Immunol. , vol.35 , pp. 445-458
    • Swanson, B.J.1    Jäck, H.M.2    Lyons, G.E.3
  • 14
    • 44049105823 scopus 로고    scopus 로고
    • Transcription factor mef2c is required forbcell proliferation and survival after antigen receptor stimulation
    • Wilker PR,KohyamaM, SandauMM, et al.Transcription factor Mef2c is required forBcell proliferation and survival after antigen receptor stimulation. Nat Immunol 2008;9:603-612.
    • (2008) Nat. Immunol. , vol.9 , pp. 603-612
    • Wilker, P.R.1    Kohyama, M.2    Sandau, M.M.3
  • 15
    • 60749111430 scopus 로고    scopus 로고
    • Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c
    • Stehling-Sun S, Dade J, Nutt SL, DeKoter RP, Camargo FD. Regulation of lymphoid versus myeloid fate 'choice' by the transcription factor Mef2c. Nat Immunol 2009;10:289-296.
    • (2009) Nat. Immunol. , vol.10 , pp. 289-296
    • Stehling-Sun, S.1    Dade, J.2    Nutt, S.L.3    DeKoter, R.P.4    Camargo, F.D.5
  • 16
    • 70350495169 scopus 로고    scopus 로고
    • Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C
    • Schwieger M, Schü ler A, Forster M, et al. Homing and invasiveness of MLL/ENL leukemic cells is regulated by MEF2C. Blood 2009;114:2476-2488.
    • (2009) Blood , vol.114 , pp. 2476-2488
    • Schwieger, M.1    Schüler, A.2    Forster, M.3
  • 17
    • 64049095814 scopus 로고    scopus 로고
    • HOXA9 is required for survival in human MLL-rearranged acute leukemias
    • Faber J, Krivtsov AV, Stubbs MC, et al. HOXA9 is required for survival in human MLL-rearranged acute leukemias. Blood 2009;113:2375-2385.
    • (2009) Blood , vol.113 , pp. 2375-2385
    • Faber, J.1    Krivtsov, A.V.2    Stubbs, M.C.3
  • 19
    • 75649149337 scopus 로고    scopus 로고
    • Modeling the functional heterogeneity of leukemia stem cells: Role of STAT5 in leukemia stem cell self-renewal
    • Heuser M, Sly LM, Argiropoulos B, et al. Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal. Blood 2009;114: 3983-3993.
    • (2009) Blood , vol.114 , pp. 3983-3993
    • Heuser, M.1    Sly, L.M.2    Argiropoulos, B.3
  • 20
    • 0141611749 scopus 로고    scopus 로고
    • Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA
    • Scherr M, Battmer K, Ganser A, Eder M. Modulation of gene expression by lentiviral-mediated delivery of small interfering RNA. Cell Cycle 2003;2:251-257.
    • (2003) Cell Cycle. , vol.2 , pp. 251-257
    • Scherr, M.1    Battmer, K.2    Ganser, A.3    Eder, M.4
  • 21
    • 0037450634 scopus 로고    scopus 로고
    • STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta
    • Xu M, Nie L, Kim SH, Sun XH. STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPbeta. EMBO J 2003;22:893-904.
    • (2003) EMBO J. , vol.22 , pp. 893-904
    • Xu, M.1    Nie, L.2    Kim, S.H.3    Sun, X.H.4
  • 22
    • 33847793796 scopus 로고    scopus 로고
    • Activation of TLX3 and NKX2-5 in t 5;14 q35;q32 T-cell acute lymphoblastic leukemia by remote 30-BCL11B enhancers and coregulation by PU.1 and hmga1
    • Nagel S, Scherr M, Kel A, et al. Activation of TLX3 and NKX2-5 in t(5;14)(q35;q32) T-cell acute lymphoblastic leukemia by remote 30-BCL11B enhancers and coregulation by PU.1 and HMGA1. Cancer Res 2007;67:1461-1471.
    • (2007) Cancer Res. , vol.67 , pp. 1461-1471
    • Nagel, S.1    Scherr, M.2    Kel, A.3
  • 23
    • 77449136887 scopus 로고    scopus 로고
    • High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription
    • Laurent B, Randrianarison-Huetz V, Marchal V, Mayeux P, Dusanter-Fourt I, Duménil D. High-mobility group protein HMGB2 regulates human erythroid differentiation through trans-activation of GFI1B transcription. Blood 2010;115:687-695.
    • (2010) Blood , Issue.115 , pp. 687-695
    • Laurent, B.1    Randrianarison-Huetz, V.2    Marchal, V.3    Mayeux, P.4    Dusanter-Fourt, I.5    Duménil, D.6
  • 24
    • 28844442337 scopus 로고    scopus 로고
    • Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9
    • Kawagoe H, Grosveld GC. Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9. Blood 2005;106:4269-4277.
    • (2005) Blood , vol.106 , pp. 4269-4277
    • Kawagoe, H.1    Grosveld, G.C.2
  • 25
    • 77949423437 scopus 로고    scopus 로고
    • Functional characterization of high levels of meningioma 1 as collaborating oncogene in acute leukemia
    • Liu T, Jankovic D, Brault L, et al. Functional characterization of high levels of meningioma 1 as collaborating oncogene in acute leukemia. Leukemia 2010;24:601-612.
    • (2010) Leukemia , Issue.24 , pp. 601-612
    • Liu, T.1    Jankovic, D.2    Brault, L.3
  • 26
    • 34347213447 scopus 로고    scopus 로고
    • Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation
    • Slape C, Hartung H, Lin YW, Bies J, Wolff L, Aplan PD. Retroviral insertional mutagenesis identifies genes that collaborate with NUP98-HOXD13 during leukemic transformation. Cancer Res 2007;67:5148-5155.
    • (2007) Cancer Res. , vol.67 , pp. 5148-5155
    • Slape, C.1    Hartung, H.2    Lin, Y.W.3    Bies, J.4    Wolff, L.5    Aplan, P.D.6
  • 27
    • 0029892570 scopus 로고    scopus 로고
    • Isolation and characterization of nmi a novel partner of myc proteins
    • Bao J, Zervos AS. Isolation and characterization of Nmi, a novel partner of Myc proteins. Oncogene 1996;12:2171-2176.
    • (1996) Oncogene. , vol.12 , pp. 2171-2176
    • Bao, J.1    Zervos, A.S.2
  • 28
    • 0033534562 scopus 로고    scopus 로고
    • Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgammamediated signaling
    • Zhu M, John S, Berg M, Leonard WJ. Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgammamediated signaling. Cell 1999;96:121-130.
    • (1999) Cell , vol.96 , pp. 121-130
    • Zhu, M.1    John, S.2    Berg, M.3    Leonard, W.J.4
  • 30
    • 0033136288 scopus 로고    scopus 로고
    • Distinct roles of the phosphatidylinositol 3-kinase and stat5 pathways in il-7-mediated development of human thymocyte precursors
    • Pallard C, Stegmann AP, van Kleffens T, Smart F, Venkitaraman A, Spits H. Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 1999;10:525-535.
    • (1999) Immunity , vol.10 , pp. 525-535
    • Pallard, C.1    Stegmann, A.P.2    Van Kleffens, T.3    Smart, F.4    Venkitaraman, A.5    Spits, H.6
  • 32
    • 77049121268 scopus 로고    scopus 로고
    • Multiple mechanisms induce ectopic expression of LYL1 in subsets of T-ALL cell lines
    • Nagel S, Venturini L, Meyer C, et al. Multiple mechanisms induce ectopic expression of LYL1 in subsets of T-ALL cell lines. Leuk Res 2010;34:521-528.
    • (2010) Leuk. Res. , Issue.34 , pp. 521-528
    • Nagel, S.1    Venturini, L.2    Meyer, C.3
  • 33
    • 0027201165 scopus 로고
    • SIL-TAL1 deletion in T-cell acute lymphoblastic leukemia
    • Janssen JW, Ludwig WD, Sterry W, Bartram CR. SIL-TAL1 deletion in T-cell acute lymphoblastic leukemia. Leukemia 1993;7:1204-1210.
    • (1993) Leukemia , vol.7 , pp. 1204-1210
    • Janssen, J.W.1    Ludwig, W.D.2    Sterry, W.3    Bartram, C.R.4
  • 34
    • 65149100673 scopus 로고    scopus 로고
    • Mef2C is a lineagerestricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis
    • Gekas C, Rhodes KE, Gereige LM, et al. Mef2C is a lineagerestricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. Blood 2009;113:3461-3471.
    • (2009) Blood , vol.113 , pp. 3461-3471
    • Gekas, C.1    Rhodes, K.E.2    Gereige, L.M.3
  • 35
    • 0035203948 scopus 로고    scopus 로고
    • The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development
    • Wang DZ, Valdez MR, McAnally J, Richardson J, Olson EN. The Mef2c gene is a direct transcriptional target of myogenic bHLH and MEF2 proteins during skeletal muscle development. Development 2001;128:4623-4633.
    • (2001) Development , vol.128 , pp. 4623-4633
    • Wang, D.Z.1    Valdez, M.R.2    McAnally, J.3    Richardson, J.4    Olson, E.N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.