STAT5-induced Id-1 transcription involves recruitment of HDAC1 and deacetylation of C/EBPβ

EMBO Journal

Volumn 22, Issue 4, 2003, Pages 893-904

  Xu, Min ^a,b   Nie, Lei ^a   Kim, Seung Hwan ^a   Sun, Xiao Hong ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetylation; Cytokine; Helix loop helix; STAT; Transcription

Indexed keywords

HELIX LOOP HELIX PROTEIN; HISTONE ACETYLTRANSFERASE; HISTONE DEACETYLASE; INTERLEUKIN 3; PROTEIN; PROTEIN CEBP BETA; STAT5 PROTEIN; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DEACETYLATION; DNA BINDING; ENHANCER REGION; GENE; GENE EXPRESSION; GENETIC TRANSCRIPTION; ID 1 GENE; NONHUMAN; PRIORITY JOURNAL;

ACETYLATION; ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); HISTONE DEACETYLASES; HUMANS; INHIBITOR OF DIFFERENTIATION PROTEIN 1; MILK PROTEINS; REPRESSOR PROTEINS; STAT5 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0037450634     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg094     Document Type: Article

References (45)

1. Boyes, J., Byfield, P., Nakatani, Y. and Ogryzko, V. (1998) Regulation of activity of the transcription factor GATA-1 by acetylation. Nature, 396, 594-598.
2. Bromberg, J. and Darnell, J.E., Jr (2000) The role of STATs in transcriptional control and their impact on cellular function. Oncogene, 19, 2468-2473.
3. Chen, H., Lin, R.J., Xie, W., Wilpitz, D. and Evans, R.M. (1999) Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. Cell, 98, 675-686.
4. Chen, H., Tini, M. and Evans, R.M. (2001) HATs on and beyond chromatin. Curr. Opin. Cell Biol., 13, 218-224.
5. Chen, L., Fischle, W., Verdin, E. and Greene, W.C. (2001) Duration of nuclear NF-κB action regulated by reversible acetylation. Science. 293, 1653-1657.
6. Descombes, P. and Schibler, U. (1991) A liver-enriched transcription activator protein, LAP and a transcription inhibitory protein. LIP, are translated from the same mRNA. Cell, 67, 569-579.
7. Engel, I. and Murre, C. (2001) The function of E- and Id proteins in lymphocyte development. Nat. Rev. Immunol., 1, 193-199.
8. Gu, W. and Roeder, R.G. (1997) Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell, 90, 595-606.
9. Heemskerk, M.H., Blom, B., Oda, K., Stegmann, A.P., Bakker, A.Q., Weijer, K., Res, P.C. and Spits, H. (1997) Inhibition of T cell and promotion of natural killer cell development by the dominant negative helix loop helix factor Id3. J. Exp. Med., 186, 1597-1602.
10. Huang, N., Katz, J.P., Martin, D.R. and Wu, G.D. (1997) Inhibition of IL-8 gene expression in Caco-2 cells by compounds which induce histone hyperacetylation. Cytokine, 9, 27-36.
11. Hung, H.L., Lau, J., Kim, A.Y., Weiss, M.J. and Blobel, G.A. (1999) CREB-binding protein acetylates hematopoietic transcription factor GATA-1 at functionally important sites. Mol. Cell. Biol., 19, 3496-3505.
12. Igarashi, H., Gregory, S.C., Yokota, T., Sakaguchi, N. and Kincade, P.W. (2002) Transcription from the RAG1 locus marks the earliest lymphocyte progenitors in bone marrow. Immunity, 17, 117-130.
13. Imhof, A., Yang, X.J., Ogryzko, V.V., Nakatani, Y., Wolffe, A.P. and Ge, H. (1997) Acetylation of general transcription factors by histone acetyltransferases. Curr. Biol., 7, 689-692.
14. Jaleco, A.C., Stegmann, A.P., Heemskerk, M.H., Couwenberg, F., Bakker, A.Q., Weijer, K. and Spits, H. (1999) Genetic modification of human B-cell development: B-cell development is inhibited by the dominant negative helix loop helix factor Id3. Blood, 94, 2637-2646.
15. Kim, D., Peng, X.C. and Sun, X.H. (1999) Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice. Mol. Cell. Biol., 19, 8240-8253.
16. Kim, D., Xu, M., Nie, L., Peng, X.C., Jimi, E., Voll, R.E., Nguyen, T., Ghosh, S. and Sun, X.H. (2002) Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-κB activities. Immunity. 16, 9-21.
17. Kinashi, T., Inaba, K., Tsubata, T., Tashiro, K., Palacios, R. and Honjo, T. (1988) Differentiation of an interleukin 3-dependent precursor B-cell clone into immunoglobulin-producing cells in vitro. Proc. Natl Acad. Sci. USA, 85, 4473-4477.
18. Kouzarides, T. (2000) Acetylation: a regulatory modification to rival phosphorylation? EMBO J., 19, 1176-1179.
19. Koyama, Y., Adachi, M., Sekiya, M., Takekawa, M. and Imai, K. (2000) Histone deacetylase inhibitors suppress IL-2-mediated gene expression prior to induction of apoptosis. Blood, 96, 1490-1495.
20. Lin, J.X. and Leonard, W.J. (2000) The role of Stat5a and Stat5b in signaling by IL-2 family cytokines. Oncogene, 19, 2566-2576.
21. Luo, J., Nikolaev, A.Y., Imai, S., Chen, D., Su, F., Shiloh, A., Guarente, L. and Gu. W. (2001) Negative control of p53 by Sir2α promotes cell survival under stress. Cell, 107, 137-148.
22. Marmorstein, R. and Roth, S.Y. (2001) Histone acetyltransferases: function, structure and catalysis. Curr. Opin. Genet. Dev., 11, 155-161.
23. Massari, M.E. and Murre, C. (2000) Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms. Mol. Cell. Biol., 20, 429-440.
24. Mishra, N., Brown, D.R., Olorenshaw, I.M. and Kammer, G.M. (2001) Trichostatin A reverses skewed expression of CD154, interleukin-10 and interferon-γ gene and protein expression in lupus T cells. Proc. Natl Acad. Sci. USA, 98, 2628-2633.
25. Mui, A.L., Wakao, H., Kinoshita, T., Kitamura, T. and Miyajima, A. (1996) Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation. EMBO J., 15, 2425-2433.
26. Norton, J.D., Deed, R.W., Craggs, G. and Sablitzky, F. (1998) Id helix-loop-helix proteins in cell growth and differentiation. Trends Cell Biol., 8, 58-65.
27. Pui, J.C. et al. (1999) Notchl expression in early lymphopoiesis influences B versus T lineage determination. Immunity, 11, 299-308.
28. Reddy, E.P., Korapati, A., Chaturvedi, P. and Rane S. (2000) IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled. Oncogene, 19, 2532-2547.
29. Ron, D. and Habener, J.F. (1992) CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription. Genes Dev., 6, 439-453.
30. Saisanit, S. and Sun, X.H. (1995) A novel enhancer, the pro-β enhancer, regulates Id1 gene expression in progenitor B cells. Mol. Cell. Biol., 15, 1513-1521.
31. Saisanit, S. and Sun, X.H. (1997) Regulation of the pro-β-cell-specific enhancer of the Id1 gene involves the C/EBP family of proteins. Mol. Cell. Biol., 17, 844-850.
32. Sartorelli, V., Puri, P.L., Hamamori, Y., Ogryzko, V., Chung, G., Nakatani, Y., Wang, J.Y. and Kedes, L. (1999) Acetylation of MyoD directed by PCAF is necessary for the execution of the muscle program. Mol. Cell, 4, 725-734.
33. Struhl, K. (1998) Histone acetylation and transcriptional regulatory mechanisms. Genes Dev., 12, 599-606.
34. Sun, X.-H. (1994) Constitutive expression of the Id1 gene impairs mouse B cell development. Cell, 79, 893-900.
35. Tyler, J.K. and Kadonaga, J.T. (1999) The 'dark side' of chromatin remodeling: repressive effects on transcription. Cell, 99, 443-446.
36. Van Lint, C., Emiliani, S. and Verdin, E. (1996) The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation. Gene Expr., 5, 245-253.
37. Vidal, M. and Gaber, R.F. (1991) RPD3 encodes a second factor required to achieve maximum positive and negative transcriptional states in Saccharomyces cerevisiae. Mol. Cell. Biol., 11, 6317-6327.
38. Vitola, S.J., Wang, A. and Sun, X.H. (1996) Substitution of basic amino acids in the basic region stabilizes DNA binding by E12 homodimers. Nucleic Acids Res., 24, 1921-1927.
39. Wakao, H., Gouilleux, F. and Groner, B. (1994) Mammary gland factor (MGF) is a novel member of the cytokine regulated transcription factor gene family and confers the prolactin response. EMBO J., 13, 2182-2191.
40. Waltzer, L. and Bienz, M. (1998) Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature, 395, 521-525.
41. Wang, A., Kurdistani, S.K. and Grunstein, M. (2002) Requirement of Hos2 histone deacetylase for gene activity in yeast. Science, 298, 1412-1414.
42. Williams, S.C., Baer, M., Dillner, A.J. and Johnson, P.F. (1995) CRP2 (C/EBPβ) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity. EMBO J., 14, 3170-3183.
43. Wolf, D., Rodova, M., Miska, E.A., Calvet, J.P. and Kouzarides, T. (2002) Acetylation of β-catenin by CBP. J. Biol. Chem., 277, 25562-25567.
44. Yamagata, T., Mitani, K., Oda, H., Suzuki, T., Honda, H., Asai, T., Maki, K., Nakamoto, T. and Hirai, H. (2000) Acetylation of GATA-3 affects T-cell survival and homing to secondary lymphoid organs. EMBO J., 19, 4676-4687.
45. Zhang, W. and Bieker, J.J. (1998) Acetylation and modulation of erythroid Kruppel-like factor (EKLF) activity by interaction with histone acetyltransferases. Proc. Natl Acad. Sci. USA, 95, 9855-9860.