STAT5 is required for thymopoiesis in a development stage-specific manner

Journal of Immunology

Volumn 173, Issue 4, 2004, Pages 2307-2314

  Kang, Joonsoo ^a   DiBenedetto, Brian ^a   Narayan, Kavitha ^a   Zhao, Hang ^a   Der, Sandy D ^b   Chambers, Cynthia A ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 7; STAT5 PROTEIN; T LYMPHOCYTE RECEPTOR DELTA CHAIN; T LYMPHOCYTE RECEPTOR GAMMA CHAIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; FETUS DEVELOPMENT; GENE CONTROL; GENETIC TRANSCRIPTION; IN VIVO STUDY; LYMPHOPOIESIS; MOUSE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN FUNCTION; THYMOCYTE;

EID: 4043133786     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.4.2307     Document Type: Article

References (49)

1. Corcoran, A. E., F. M. Smart, R. J. Cowling, T. Crompton, M. J. Owen, and A. R. Venkitaraman. 1996. The interleukin-7 receptor α chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis. EMBO J. 15:1924.
2. Maki, K., S. Sunaga, and K. Ikuta. 1996. The V-J recombination of T cell receptor-γ genes is blocked in interleukin-7 receptor-deficient mice. J. Exp. Med. 184:2423.
3. von Freeden-Jeffry, U., N. Solvason, M. Howard, and R. Murray. 1997. The earliest T lineage-committed cells depend on IL-7 for Bcl-2 expression and normal cell cycle progression. Immunity 7:147.
4. Pallard, C., A. P. Stegmann, T. van Kleffens, F. Smart, A. Venkitaraman, and H. Spits. 1999. Distinct roles of the phosphatidylinositol 3-kinase and STAT5 pathways in IL-7-mediated development of human thymocyte precursors. Immunity 10:525.
5. Peschon, J. J., P. J. Morrissey, K. H. Grabstein, F. J. Ramsdell, E. Maraskovsky, B. C. Gliniak, L. S. Park, S. F. Ziegler, D. E. Williams, C. B. Ware, et al. 1994. Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice. J. Exp. Med. 180:1955.
6. von Freeden-Jeffry, U., P. Vieira, L. A. Lucian, T. McNeil, S. E. Burdach, and R. Murray. 1995. Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine. J. Exp. Med. 181:1519.
7. Berg, L. J., and J. Kang. 2001. Molecular determinants of TCR expression and selection. Curr. Opin. Immunol. 13:232.
8. Durum, S. K., S. Candèias, H. Nakajima, W. J. Leonard, A. M. Baird, L. J. Berg, and K. Muegge. 1998. Interleukin 7 receptor control of T cell receptor γ gene rearrangement: role of receptor-associated chains and locus accessibility. J. Exp. Med. 188:2233.
9. Schlissel, M. S., S. D. Durum, and K. Muegge. 2000. The interleukin 7 receptor is required for T cell receptor γ locus accessibility to the V(D)J recombinase. J. Exp. Med. 191:1045.
10. Ye, S. K., Y. Agata, H. C. Lee, H. Kurooka, T. Kitamura, A. Shimizu, T. Honjo, and K. Ikuta. 2001. The IL-7 receptor controls the accessibility of the TCR γ locus by Stat5 and histone acetylation. Immunity 15:813.
11. Fleming, H. E., and C. J. Paige. 2001. Pre-B cell receptor signaling mediates selective response to IL-7 at the pro-B to pre-B cell transition via an ERK/MAP kinase-dependent pathway. Immunity 15:521.
12. Ye, S., K. Maki, T. Kitamura, S. Sunaga, K. Akashi, J. Domen, I. L. Weissman, T. Honjo, and K. Ikuta. 1999. Induction of germline transcription in the TCRγ locus by Stat5: implications for accessibility control by the IL-7 receptor. Immunity 11:213.
13. Perumal, N. B., T. W. Kenniston, Jr., D. J. Tweardy, K. F. Dyer, R. Hoffman, J. Peschon, and P. M. Appasamy. 1997. TCR-γ genes are rearranged but not transcribed in IL-7Rα-deficient mice. J. Immunol. 158:5744.
14. Baker, J. E., J. Kang, T. Chen, D. Cado, and D. H. Raulet. 1999. A novel element upstream of the Vγ2 gene in the murine T cell receptor γ locus cooperates with the 3′ enhancer to act as a locus control region. J. Exp. Med. 190:669.
15. Porter, B. O., P. Scibelli, and T. R. Malek. 2001. Control of T cell development in vivo by subdomains within the IL-7 receptor α-chain cytoplasmic tail. J. Immunol. 166:262.
16. Nakajima, H., X. W. Liu, A. Wynshaw-Boris, L. A. Rosenthal, K. Imada, D. S. Finbloom, L. Hennighausen, and W. J. Leonard. 1997. An indirect effect of Stat5a in IL-2-induced proliferation: a critical role for Stat5a in IL-2-mediated IL-2 receptor α chain induction. Immunity 7:691.
17. Imada, K., E. T. Bloom, H. Nakajima, J. A. Horvath-Arcidiacono, G. B. Udy, H. W. Davey, and W. J. Leonard. 1998. Stat5b is essential for natural killer cell-mediated proliferation and cytolytic activity. J. Exp. Med. 188:2067.
18. Teglund, S., C. McKay, E. Schuetz, J. van Deursen, D. Stravopodis, D. Wang, M. Browm, S. Bodner, G. Grosveld, and J. N. Ihle. 1998. Stat5a and Stat5b proteins have essential and non-essential, or redundant, roles in cytokine responses. Cell 93:841.
19. Moriggl, R., D. J. Topham, S. Teglund, V. Sexl, C. McKay, D. Wang, A. Hoffmeyer, J. van Deursen, M. Y. Sangster, K. D. Bunting, et al. 1999. Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity 10:249.
20. Bunting, K. D., H. L. Bradley, T. S. Hawley, R. Moriggl, B. P. Sorrentino, and J. N. Ihle. 2002. Reduced lymphomyeloid repopulating activity from adult bone marrow and fetal liver of mice lacking expression of STAT5. Blood 99:479.
21. Snow, J. W., N. Abraham, M. C. Ma, N. W. Abbey, B. Herndier, and M. A. Goldsmith. 2002. STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells. Blood 99:95.
22. Bradley, H. L., T. S. Hawley, and K. D. Bunting. 2002. Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells. Blood 100:3983.
23. - cells in the embryonic intestine induces the organizing center of Peyer's patches. Int. Immunol. 11:643.
24. Kennedy, M. K., M. Glaccum, S. N. Brown, E. A. Butz, J. L. Viney, M. Embers, N. Matsuki, K. Charrier, L. Sedger, C. R. Willis, et al. 2000. Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice. J. Exp. Med. 191:771.
25. 1 integrin activation by CXCR5. Immunity 17:363.
26. Goldman, J., D. Spencer, and D. Raulet. 1993. Ordered rearrangement of variable region genes of the T cell receptor γ locus correlates with transcription of the unrearranged genes. J. Exp. Med. 177:729.
27. Itohara, S., P. Mombaerts, J. Lafaille, J. Iacomini, A. Nelson, A. R. Clarke, M. L. Hooper, A. Farr, and S. Tonegawa. 1993. T cell receptor 8 gene mutant mice: independent generation of αβ T cells and programmed rearrangements of γδ TCR genes. Cell 72:337.
28. Allison, J. P., and W. L. Havran. 1991. The immunobiology of T cells with invariant γδ antigen receptors. Annu. Rev. Immunol. 9:679.
29. Crompton, T., S. V. Outram, J. Buckland, and M. J. Owen. 1998. Distinct roles of the interleukin-7 receptor α chain in fetal and adult thymocyte development revealed by analysis of interleukin-7 receptor α-deficient mice. Eur. J. Immunol. 28:1859.
30. Kang, J., M. Coles, D. Cado, and D. H. Raulet. 1998. The developmental fate of T cells is critically influenced by TCRγδ expression. Immunity 8:427.
31. Kang, J., M. Coles, and D. H. Raulet. 1999. Defective development of γδ T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor γ genes. J. Exp. Med. 190:973.
32. Kawai, K., H. Suzuki, K. Tomiyama, M. Minagawa, T. W. Mak, and P. S. Ohashi. 1998. Requirement of the IL-2 receptor β chain for the development of Vγ3 dendritic epidermal T cells. J. Invest. Dermatol. 110:961.
33. Adachi, S., H. Yoshida, H. Kataoka, and S. Nishikawa. 1997. Three distinctive steps in Peyer's patch formation of murine embryo. Int. Immunol. 9:507.
34. Kincade, P. W., J. J. Owen, H. Igarashi, T. Kouro, T. Yokota, and M. I. Rossi. 2002. Nature or nurture? Steady-state lymphocyte formation in adults does not recapitulate ontogeny. Immunol. Rev. 187:116.
35. Laky, K., L. Lefrancois, E. G. Lingenheld, H. Ishikawa, J. M. Lewis, S. Olson, K. Suzuki, R. E. Tigelaar, and L. Puddington. 2000. Enterocyte expression of interleukin 7 induces development of γδ T cells and Peyer's patches. J. Exp. Med. 191:1569.
36. Jameson, S. C. 2002. Maintaining the norm: T-cell homeostasis. Nat. Rev. Immunol. 2:547.
37. Lodolce, J. P., D. L. Boone, S. Chai, R. E. Swain, T. Dassopoulos, S. Trettin, and A. Ma. 1998. IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation. Immunity 9:669.
38. Maki, K., S. Sunaga, Y. Komagata, Y. Kodaira, A. Mabuchi, H. Karasuyama, K. Yokomuro, J. I. Miyazaki, and K. Ikuta. 1996. Interleukin 7 receptor-deficient mice lack γδ T cells. Proc. Natl. Acad. Sci. USA 93:7172.
39. Suzuki, H., G. S. Duncan, H. Takimoto, and T. W. Mak. 1997. Abnormal development of intestinal intraepithelial lymphocytes and peripheral natural killer cells in mice lacking the IL-2 receptor β chain. J. Exp. Med. 185:499.
40. Contractor, N. V., H. Bassiri, T. Reya, A. Y. Park, D. C. Baumgart, M. A. Wasik, S. G. Emerson, and S. R. Carding. 1998. Lymphoid hyperplasia, autoimmunity, and compromised intestinal intraepithelial lymphocyte development in colitis-free gnotobiotic IL-2-deficient mice. J. Immunol. 160:385.
41. Chambers, C. A., M. S. Kuhns, J. G. Egen, and J. P. Allison. 2001. CTLA-4-mediated inhibition in regulation of T cell responses: mechanisms and manipulation in tumor immunotherapy. Annu. Rev. Immunol. 19:565.
42. Sexl, V., R. Piekorz, R. Moriggl, J. Rohrer, M. P. Brown, K. D. Bunting, K. Rothammer, M. F. Roussel, and J. N. Ihle. 2000. Stat5a/b contribute to interleukin 7-induced B-cell precursor expansion, but abl- and bcr/abl-induced transformation are independent of stat5. Blood 96:2277.
43. Xiong, N., C. Kang, and D. H. Raulet. 2002. Redundant and unique roles of two enhancer elements in the TCRγ locus in gene regulation and γδ T cell development. Immunity 16:453.
44. Bonifer, C., N. Faust, H. Geiger, and A. M. Muller. 1998. Developmental changes in the differentiation capacity of haematopoietic stem cells. Immunol. Today 19:236.
45. Ivanova, N. B., J. T. Dimos, C. Schaniel, J. A. Hackney, K. A. Moore, and I. R. Lemischka. 2002. A stem cell molecular signature. Science 298:601.
46. Vosshenrich, C. A., A. Cumano, W. Muller, J. P. Di Santo, and P. Vieira. 2003. Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development. Nat. Immunol. 4:773.
47. Isaksen, D. E., H. Baumann, P. A. Trobridge, A. G. Farr, S. D. Levin, and S. F. Ziegler. 1999. Requirement for stat5 in thymic stromal lymphopoietin-mediated signal transduction. J. Immunol. 163:5971.
48. Sims, J. E., D. E. Williams, P. J. Morrissey, K. Garka, D. Foxworthe, V. Price, S. L. Friend, A. Farr, M. A. Bedell, N. A. Jenkins, et al. 2000. Molecular cloning and biological characterization of a novel murine lymphoid growth factor. J. Exp. Med. 192:671.
49. L induction. Cell 98:181.