-
1
-
-
0023903134
-
Standardized and simplified nomenclature for proteins common to all retroviruses
-
1:CAS:528:DyaL1cXktlOhtbo%3D
-
J Leis D Baltimore JM Bishop, et al. 1988 Standardized and simplified nomenclature for proteins common to all retroviruses J Virol 62 1808 1809 1:CAS:528:DyaL1cXktlOhtbo%3D
-
(1988)
J Virol
, vol.62
, pp. 1808-1809
-
-
Leis, J.1
Baltimore, D.2
Bishop, J.M.3
-
2
-
-
0025286146
-
Mutational analysis of a native substrate of the human immunodeficiency virus type 1 proteinase
-
1:CAS:528:DyaK3cXkvFertb0%3D
-
K Partin HG Krausslich L Ehrlich, et al. 1990 Mutational analysis of a native substrate of the human immunodeficiency virus type 1 proteinase J Virol 64 3938 3947 1:CAS:528:DyaK3cXkvFertb0%3D
-
(1990)
J Virol
, vol.64
, pp. 3938-3947
-
-
Partin, K.1
Krausslich, H.G.2
Ehrlich, L.3
-
3
-
-
0027491307
-
The gag precursor contains a specific HIV-1 protease cleavage site between the NC (P7) and P1 proteins
-
1:CAS:528:DyaK3sXms1CqtrY%3D 10.1016/0014-5793(93)80367-4
-
EM Wondrak JM Louis H de Rocquigny, et al. 1993 The gag precursor contains a specific HIV-1 protease cleavage site between the NC (P7) and P1 proteins FEBS Lett 333 21 24 1:CAS:528:DyaK3sXms1CqtrY%3D 10.1016/0014-5793(93) 80367-4
-
(1993)
FEBS Lett
, vol.333
, pp. 21-24
-
-
Wondrak, E.M.1
Louis, J.M.2
De Rocquigny, H.3
-
4
-
-
0032562202
-
Hydrophilic peptides derived from the transframe region of Gag-Pol inhibit the HIV-1 protease
-
1:CAS:528:DyaK1cXotFGkug%3D%3D 10.1021/bi972059x
-
JM Louis F Dyda NT Nashed, et al. 1998 Hydrophilic peptides derived from the transframe region of Gag-Pol inhibit the HIV-1 protease Biochemistry 37 2105 2110 1:CAS:528:DyaK1cXotFGkug%3D%3D 10.1021/bi972059x
-
(1998)
Biochemistry
, vol.37
, pp. 2105-2110
-
-
Louis, J.M.1
Dyda, F.2
Nashed, N.T.3
-
5
-
-
0023755462
-
The gag gene products of human immunodeficiency virus type 1: Alignment within the gag open reading frame, identification of posttranslational modifications, and evidence for alternative gag precursors
-
1:CAS:528:DyaL1MXkt1Cr
-
RJ Mervis N Ahmad EP Lillehoj, et al. 1988 The gag gene products of human immunodeficiency virus type 1: alignment within the gag open reading frame, identification of posttranslational modifications, and evidence for alternative gag precursors J Virol 62 3993 4002 1:CAS:528:DyaL1MXkt1Cr
-
(1988)
J Virol
, vol.62
, pp. 3993-4002
-
-
Mervis, R.J.1
Ahmad, N.2
Lillehoj, E.P.3
-
6
-
-
0024338208
-
Identification of protein intermediates in the processing of the p55 HIV-1 gag precursor in cells infected with recombinant vaccinia virus
-
1:CAS:528:DyaL1MXkt1SltLs%3D
-
SD Gowda BS Stein EG Engleman 1989 Identification of protein intermediates in the processing of the p55 HIV-1 gag precursor in cells infected with recombinant vaccinia virus J Biol Chem 264 8459 8462 1:CAS:528: DyaL1MXkt1SltLs%3D
-
(1989)
J Biol Chem
, vol.264
, pp. 8459-8462
-
-
Gowda, S.D.1
Stein, B.S.2
Engleman, E.G.3
-
7
-
-
1542502945
-
Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides
-
1:CAS:528:DyaL1MXhsFSht7k%3D 10.1073/pnas.86.3.807
-
HG Krausslich RH Ingraham MT Skoog, et al. 1989 Activity of purified biosynthetic proteinase of human immunodeficiency virus on natural substrates and synthetic peptides Proc Natl Acad Sci USA 86 807 811 1:CAS:528: DyaL1MXhsFSht7k%3D 10.1073/pnas.86.3.807
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 807-811
-
-
Krausslich, H.G.1
Ingraham, R.H.2
Skoog, M.T.3
-
8
-
-
0027971621
-
The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions
-
1:CAS:528:DyaK2MXitFylsrY%3D
-
SC Pettit MD Moody RS Wehbie, et al. 1994 The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions J Virol 68 8017 8027 1:CAS:528:DyaK2MXitFylsrY%3D
-
(1994)
J Virol
, vol.68
, pp. 8017-8027
-
-
Pettit, S.C.1
Moody, M.D.2
Wehbie, R.S.3
-
9
-
-
0029417217
-
In vivo processing of Pr160gag-pol from human immunodeficiency virus type 1 (HIV) in acutely infected, cultured human T-lymphocytes
-
1:CAS:528:DyaK28Xislynug%3D%3D 10.1006/viro.1995.0074
-
H Lindhofer K von der Helm H Nitschko 1995 In vivo processing of Pr160gag-pol from human immunodeficiency virus type 1 (HIV) in acutely infected, cultured human T-lymphocytes Virology 214 624 627 1:CAS:528: DyaK28Xislynug%3D%3D 10.1006/viro.1995.0074
-
(1995)
Virology
, vol.214
, pp. 624-627
-
-
Lindhofer, H.1
Von Der Helm, K.2
Nitschko, H.3
-
10
-
-
0029665574
-
A p6Pol-protease fusion protein is present in mature particles of human immunodeficiency virus type 1
-
1:CAS:528:DyaK28XlslWjsbc%3D
-
N Almog R Roller G Arad, et al. 1996 A p6Pol-protease fusion protein is present in mature particles of human immunodeficiency virus type 1 J Virol 70 7228 7232 1:CAS:528:DyaK28XlslWjsbc%3D
-
(1996)
J Virol
, vol.70
, pp. 7228-7232
-
-
Almog, N.1
Roller, R.2
Arad, G.3
-
11
-
-
0031925586
-
Sequential steps in human immunodeficiency virus particle maturation revealed by alterations of individual Gag polyprotein cleavage sites
-
1:CAS:528:DyaK1cXhvVOisLg%3D
-
K Wiegers G Rutter H Kottler, et al. 1998 Sequential steps in human immunodeficiency virus particle maturation revealed by alterations of individual Gag polyprotein cleavage sites J Virol 72 2846 2854 1:CAS:528: DyaK1cXhvVOisLg%3D
-
(1998)
J Virol
, vol.72
, pp. 2846-2854
-
-
Wiegers, K.1
Rutter, G.2
Kottler, H.3
-
12
-
-
0036784575
-
Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease
-
1:CAS:528:DC%2BD38XnsV2ktL0%3D 10.1128/JVI.76.20.10226-10233.2002
-
SC Pettit GJ Henderson CA Schiffer, et al. 2002 Replacement of the P1 amino acid of human immunodeficiency virus type 1 Gag processing sites can inhibit or enhance the rate of cleavage by the viral protease J Virol 76 10226 10233 1:CAS:528:DC%2BD38XnsV2ktL0%3D 10.1128/JVI.76.20.10226-10233.2002
-
(2002)
J Virol
, vol.76
, pp. 10226-10233
-
-
Pettit, S.C.1
Henderson, G.J.2
Schiffer, C.A.3
-
13
-
-
3543142335
-
Initial cleavage of the human immunodeficiency virus type 1 GagPol precursor by its activated protease occurs by an intramolecular mechanism
-
1:CAS:528:DC%2BD2cXmslSntLc%3D 10.1128/JVI.78.16.8477-8485.2004
-
SC Pettit LE Everitt S Choudhury, et al. 2004 Initial cleavage of the human immunodeficiency virus type 1 GagPol precursor by its activated protease occurs by an intramolecular mechanism J Virol 78 8477 8485 1:CAS:528: DC%2BD2cXmslSntLc%3D 10.1128/JVI.78.16.8477-8485.2004
-
(2004)
J Virol
, vol.78
, pp. 8477-8485
-
-
Pettit, S.C.1
Everitt, L.E.2
Choudhury, S.3
-
14
-
-
23244441900
-
Ordered processing of the human immunodeficiency virus type 1 GagPol precursor is influenced by the context of the embedded viral protease
-
1:CAS:528:DC%2BD2MXntFCqsrc%3D 10.1128/JVI.79.16.10601-10607.2005
-
SC Pettit JC Clemente JA Jeung, et al. 2005 Ordered processing of the human immunodeficiency virus type 1 GagPol precursor is influenced by the context of the embedded viral protease J Virol 79 10601 10607 1:CAS:528:DC%2BD2MXntFCqsrc%3D 10.1128/JVI.79.16.10601-10607.2005
-
(2005)
J Virol
, vol.79
, pp. 10601-10607
-
-
Pettit, S.C.1
Clemente, J.C.2
Jeung, J.A.3
-
15
-
-
27744572130
-
Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates
-
10.1186/1742-4690-2-66
-
SC Pettit JN Lindquist AH Kaplan, et al. 2005 Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates Retrovirology 2 66 10.1186/1742-4690-2-66
-
(2005)
Retrovirology
, vol.2
, pp. 66
-
-
Pettit, S.C.1
Lindquist, J.N.2
Kaplan, A.H.3
-
16
-
-
0025922096
-
Mutating P2 and P1 residues at cleavage junctions in the HIV-1 pol polyprotein. Effects on hydrolysis by HIV-1 proteinase
-
1:CAS:528:DyaK3MXksVGqtbg%3D 10.1016/0014-5793(91)80583-O
-
RA Jupp LH Phylip JS Mills, et al. 1991 Mutating P2 and P1 residues at cleavage junctions in the HIV-1 pol polyprotein. Effects on hydrolysis by HIV-1 proteinase FEBS Lett 283 180 184 1:CAS:528:DyaK3MXksVGqtbg%3D 10.1016/0014-5793(91)80583-O
-
(1991)
FEBS Lett
, vol.283
, pp. 180-184
-
-
Jupp, R.A.1
Phylip, L.H.2
Mills, J.S.3
-
17
-
-
0026086220
-
Mutagenesis of protease cleavage sites in the human immunodeficiency virus type 1 gag polyprotein
-
1:CAS:528:DyaK3MXpsF2nuw%3D%3D
-
RJ Tritch YE Cheng FH Yin, et al. 1991 Mutagenesis of protease cleavage sites in the human immunodeficiency virus type 1 gag polyprotein J Virol 65 922 930 1:CAS:528:DyaK3MXpsF2nuw%3D%3D
-
(1991)
J Virol
, vol.65
, pp. 922-930
-
-
Tritch, R.J.1
Cheng, Y.E.2
Yin, F.H.3
-
18
-
-
0034283345
-
How does a symmetric dimer recognize an asymmetric substrate? A substrate complex of HIV-1 protease
-
1:CAS:528:DC%2BD3cXmtVKls7o%3D 10.1006/jmbi.2000.4018
-
M Prabu-Jeyabalan E Nalivaika CA Schiffer 2000 How does a symmetric dimer recognize an asymmetric substrate? A substrate complex of HIV-1 protease J Mol Biol 301 1207 1220 1:CAS:528:DC%2BD3cXmtVKls7o%3D 10.1006/jmbi.2000.4018
-
(2000)
J Mol Biol
, vol.301
, pp. 1207-1220
-
-
Prabu-Jeyabalan, M.1
Nalivaika, E.2
Schiffer, C.A.3
-
19
-
-
0036121219
-
Substrate shape determines specificity of recognition for HIV-1 protease: Analysis of crystal structures of six substrate complexes
-
1:CAS:528:DC%2BD38XhvVCgu7w%3D 10.1016/S0969-2126(02)00720-7
-
M Prabu-Jeyabalan E Nalivaika CA Schiffer 2002 Substrate shape determines specificity of recognition for HIV-1 protease: analysis of crystal structures of six substrate complexes Structure 10 369 381 1:CAS:528:DC%2BD38XhvVCgu7w%3D 10.1016/S0969-2126(02)00720-7
-
(2002)
Structure
, vol.10
, pp. 369-381
-
-
Prabu-Jeyabalan, M.1
Nalivaika, E.2
Schiffer, C.A.3
-
20
-
-
5444247213
-
Combating susceptibility to drug resistance: Lessons from HIV-1 protease
-
1:CAS:528:DC%2BD2cXos1Ciu78%3D
-
NM King M Prabu-Jeyabalan EA Nalivaika, et al. 2004 Combating susceptibility to drug resistance: lessons from HIV-1 protease Chem Biol 11 1333 1338 1:CAS:528:DC%2BD2cXos1Ciu78%3D
-
(2004)
Chem Biol
, vol.11
, pp. 1333-1338
-
-
King, N.M.1
Prabu-Jeyabalan, M.2
Nalivaika, E.A.3
-
21
-
-
6344231715
-
Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor
-
1:CAS:528:DC%2BD2cXptVKlsbw%3D 10.1128/JVI.78.21.12012-12021.2004
-
NM King M Prabu-Jeyabalan EA Nalivaika, et al. 2004 Structural and thermodynamic basis for the binding of TMC114, a next-generation human immunodeficiency virus type 1 protease inhibitor J Virol 78 12012 12021 1:CAS:528:DC%2BD2cXptVKlsbw%3D 10.1128/JVI.78.21.12012-12021.2004
-
(2004)
J Virol
, vol.78
, pp. 12012-12021
-
-
King, N.M.1
Prabu-Jeyabalan, M.2
Nalivaika, E.A.3
-
22
-
-
7644230388
-
Structural basis for coevolution of a human immunodeficiency virus type 1 nucleocapsid-p1 cleavage site with a V82A drug-resistant mutation in viral protease
-
1:CAS:528:DC%2BD2cXhtVWhu7nP 10.1128/JVI.78.22.12446-12454.2004
-
M Prabu-Jeyabalan EA Nalivaika NM King, et al. 2004 Structural basis for coevolution of a human immunodeficiency virus type 1 nucleocapsid-p1 cleavage site with a V82A drug-resistant mutation in viral protease J Virol 78 12446 12454 1:CAS:528:DC%2BD2cXhtVWhu7nP 10.1128/JVI.78.22.12446-12454.2004
-
(2004)
J Virol
, vol.78
, pp. 12446-12454
-
-
Prabu-Jeyabalan, M.1
Nalivaika, E.A.2
King, N.M.3
-
23
-
-
17244364283
-
Proteases universally recognize beta strands in their active sites
-
1:CAS:528:DC%2BD2MXhtlSqtLo%3D 10.1021/cr040669e
-
JD Tyndall T Nall DP Fairlie 2005 Proteases universally recognize beta strands in their active sites Chem Rev 105 973 999 1:CAS:528: DC%2BD2MXhtlSqtLo%3D 10.1021/cr040669e
-
(2005)
Chem Rev
, vol.105
, pp. 973-999
-
-
Tyndall, J.D.1
Nall, T.2
Fairlie, D.P.3
-
24
-
-
0034611591
-
Conformational selection of inhibitors and substrates by proteolytic enzymes: Implications for drug design and polypeptide processing
-
1:CAS:528:DC%2BD3cXhs1Wkur4%3D 10.1021/jm990315t
-
DP Fairlie JD Tyndall RC Reid, et al. 2000 Conformational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing J Med Chem 43 1271 1281 1:CAS:528: DC%2BD3cXhs1Wkur4%3D 10.1021/jm990315t
-
(2000)
J Med Chem
, vol.43
, pp. 1271-1281
-
-
Fairlie, D.P.1
Tyndall, J.D.2
Reid, R.C.3
-
25
-
-
0001616080
-
Replica-exchange molecular dynamics method for protein folding
-
1:CAS:528:DyaK1MXotVKrsLc%3D 10.1016/S0009-2614(99)01123-9
-
Y Sugita Y Okamoto 1999 Replica-exchange molecular dynamics method for protein folding Chemical Physics Letters 314 141 151 1:CAS:528: DyaK1MXotVKrsLc%3D 10.1016/S0009-2614(99)01123-9
-
(1999)
Chemical Physics Letters
, vol.314
, pp. 141-151
-
-
Sugita, Y.1
Okamoto, Y.2
-
26
-
-
0037934616
-
Understanding folding and design: Replica-exchange simulations of "trp-cage" miniproteins
-
1:CAS:528:DC%2BD3sXlt1Wrurc%3D 10.1073/pnas.1330954100
-
JW Pitera W Swope 2003 Understanding folding and design: replica-exchange simulations of "Trp-cage" miniproteins Proc Natl Acad Sci USA 100 7587 7592 1:CAS:528:DC%2BD3sXlt1Wrurc%3D 10.1073/pnas.1330954100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 7587-7592
-
-
Pitera, J.W.1
Swope, W.2
-
27
-
-
18744366086
-
Protein folding pathways from replica exchange simulations and a kinetic network model
-
1:CAS:528:DC%2BD2MXksVKgtbY%3D 10.1073/pnas.0408970102
-
M Andrec AK Felts E Gallicchio, et al. 2005 Protein folding pathways from replica exchange simulations and a kinetic network model Proc Natl Acad Sci USA 102 6801 6806 1:CAS:528:DC%2BD2MXksVKgtbY%3D 10.1073/pnas.0408970102
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6801-6806
-
-
Andrec, M.1
Felts, A.K.2
Gallicchio, E.3
-
28
-
-
18744403982
-
Interfacial folding and membrane insertion of designed peptides studied by molecular dynamics simulations
-
1:CAS:528:DC%2BD2MXksVKgtb0%3D 10.1073/pnas.0408135102
-
W Im CL Brooks 3rd 2005 Interfacial folding and membrane insertion of designed peptides studied by molecular dynamics simulations Proc Natl Acad Sci USA 102 6771 6776 1:CAS:528:DC%2BD2MXksVKgtb0%3D 10.1073/pnas.0408135102
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6771-6776
-
-
Im, W.1
Brooks III, C.L.2
-
29
-
-
27344455346
-
Reproducible polypeptide folding and structure prediction using molecular dynamics simulations
-
1:CAS:528:DC%2BD2MXhtFKmsL7N 10.1016/j.jmb.2005.09.030
-
MM Seibert A Patriksson B Hess, et al. 2005 Reproducible polypeptide folding and structure prediction using molecular dynamics simulations J Mol Biol 354 173 183 1:CAS:528:DC%2BD2MXhtFKmsL7N 10.1016/j.jmb.2005.09.030
-
(2005)
J Mol Biol
, vol.354
, pp. 173-183
-
-
Seibert, M.M.1
Patriksson, A.2
Hess, B.3
-
30
-
-
0033873929
-
Comparative protein structure modeling of genes and genomes
-
1:CAS:528:DC%2BD3cXlsFOnur0%3D 10.1146/annurev.biophys.29.1.291
-
MA Marti-Renom AC Stuart A Fiser, et al. 2000 Comparative protein structure modeling of genes and genomes Annu Rev Biophys Biomol Struct 29 291 325 1:CAS:528:DC%2BD3cXlsFOnur0%3D 10.1146/annurev.biophys.29.1.291
-
(2000)
Annu Rev Biophys Biomol Struct
, vol.29
, pp. 291-325
-
-
Marti-Renom, M.A.1
Stuart, A.C.2
Fiser, A.3
-
31
-
-
0035812694
-
Protein structure prediction and structural genomics
-
1:CAS:528:DC%2BD3MXnsFyisbY%3D 10.1126/science.1065659
-
D Baker A Sali 2001 Protein structure prediction and structural genomics Science 294 93 96 1:CAS:528:DC%2BD3MXnsFyisbY%3D 10.1126/science.1065659
-
(2001)
Science
, vol.294
, pp. 93-96
-
-
Baker, D.1
Sali, A.2
-
32
-
-
55549136017
-
Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif
-
1:CAS:528:DC%2BD1cXhtlalsLzM 10.1038/nsmb.1497
-
K Shirakawa A Takaori-Kondo M Yokoyama, et al. 2008 Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif Nat Struct Mol Biol 15 1184 1191 1:CAS:528:DC%2BD1cXhtlalsLzM 10.1038/nsmb.1497
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1184-1191
-
-
Shirakawa, K.1
Takaori-Kondo, A.2
Yokoyama, M.3
-
33
-
-
0030468331
-
Human immunodeficiency virus. Mutations in the viral protease that confer resistance to saquinavir increase the dissociation rate constant of the protease-saquinavir complex
-
1:CAS:528:DyaK2sXitFarsQ%3D%3D 10.1074/jbc.271.52.33231
-
B Maschera G Darby G Palu, et al. 1996 Human immunodeficiency virus. Mutations in the viral protease that confer resistance to saquinavir increase the dissociation rate constant of the protease-saquinavir complex J Biol Chem 271 33231 33235 1:CAS:528:DyaK2sXitFarsQ%3D%3D 10.1074/jbc.271.52.33231
-
(1996)
J Biol Chem
, vol.271
, pp. 33231-33235
-
-
Maschera, B.1
Darby, G.2
Palu, G.3
-
34
-
-
0036298514
-
Relation between sequence and structure of HIV-1 protease inhibitor complexes: A model system for the analysis of protein flexibility
-
1:CAS:528:DC%2BD38XnsVeg 10.1006/jmbi.2001.5173
-
V Zoete O Michielin M Karplus 2002 Relation between sequence and structure of HIV-1 protease inhibitor complexes: a model system for the analysis of protein flexibility J Mol Biol 315 21 52 1:CAS:528:DC%2BD38XnsVeg 10.1006/jmbi.2001.5173
-
(2002)
J Mol Biol
, vol.315
, pp. 21-52
-
-
Zoete, V.1
Michielin, O.2
Karplus, M.3
-
35
-
-
1842454635
-
HIV-1 protease molecular dynamics of a wild-type and of the V82F/I84V mutant: Possible contributions to drug resistance and a potential new target site for drugs
-
1:CAS:528:DC%2BD2cXivFaktbY%3D 10.1110/ps.03468904
-
AL Perryman JH Lin JA McCammon 2004 HIV-1 protease molecular dynamics of a wild-type and of the V82F/I84V mutant: possible contributions to drug resistance and a potential new target site for drugs Protein Sci 13 1108 1123 1:CAS:528:DC%2BD2cXivFaktbY%3D 10.1110/ps.03468904
-
(2004)
Protein Sci
, vol.13
, pp. 1108-1123
-
-
Perryman, A.L.1
Lin, J.H.2
McCammon, J.A.3
-
36
-
-
33745407153
-
Computational simulations of HIV-1 proteases-multi-drug resistance due to nonactive site mutation L90M
-
1:CAS:528:DC%2BD28XkvVehtbg%3D 10.1021/ja060682b
-
H Ode S Neya M Hata, et al. 2006 Computational simulations of HIV-1 proteases-multi-drug resistance due to nonactive site mutation L90M J Am Chem Soc 128 7887 7895 1:CAS:528:DC%2BD28XkvVehtbg%3D 10.1021/ja060682b
-
(2006)
J Am Chem Soc
, vol.128
, pp. 7887-7895
-
-
Ode, H.1
Neya, S.2
Hata, M.3
-
37
-
-
34250177944
-
Computational characterization of structural role of the non-active site mutation M36I of human immunodeficiency virus type 1 protease
-
1:CAS:528:DC%2BD2sXmsFClurw%3D 10.1016/j.jmb.2007.04.081
-
H Ode S Matsuyama M Hata, et al. 2007 Computational characterization of structural role of the non-active site mutation M36I of human immunodeficiency virus type 1 protease J Mol Biol 370 598 607 1:CAS:528:DC%2BD2sXmsFClurw%3D 10.1016/j.jmb.2007.04.081
-
(2007)
J Mol Biol
, vol.370
, pp. 598-607
-
-
Ode, H.1
Matsuyama, S.2
Hata, M.3
-
38
-
-
0029633186
-
AMBER, a package of computer programs for applying molecular mechanics, normal mode analysis, molecular dynamics and free energy calculations to simulate the structural and energetic properties of molecules
-
1:CAS:528:DyaK2MXps1Wrtrw%3D 10.1016/0010-4655(95)00041-D
-
DA Pearlman DA Case JW Caldwell, et al. 1995 AMBER, a package of computer programs for applying molecular mechanics, normal mode analysis, molecular dynamics and free energy calculations to simulate the structural and energetic properties of molecules Comp Phys Commun 91 1 41 1:CAS:528:DyaK2MXps1Wrtrw%3D 10.1016/0010-4655(95)00041-D
-
(1995)
Comp Phys Commun
, vol.91
, pp. 1-41
-
-
Pearlman, D.A.1
Case, D.A.2
Caldwell, J.W.3
-
39
-
-
0034521981
-
Calculating structures and free energies of complex molecules: Combining molecular mechanics and continuum models
-
1:CAS:528:DC%2BD3cXmvFGiu7g%3D 10.1021/ar000033j
-
PA Kollman I Massova C Reyes, et al. 2000 Calculating structures and free energies of complex molecules: combining molecular mechanics and continuum models Acc Chem Res 33 889 897 1:CAS:528:DC%2BD3cXmvFGiu7g%3D 10.1021/ar000033j
-
(2000)
Acc Chem Res
, vol.33
, pp. 889-897
-
-
Kollman, P.A.1
Massova, I.2
Reyes, C.3
-
40
-
-
33748518255
-
Comparison of multiple Amber force fields and development of improved protein backbone parameters
-
1:CAS:528:DC%2BD28XhtFWqt7fM 10.1002/prot.21123
-
V Hornak R Abel A Okur, et al. 2006 Comparison of multiple Amber force fields and development of improved protein backbone parameters Proteins 65 712 725 1:CAS:528:DC%2BD28XhtFWqt7fM 10.1002/prot.21123
-
(2006)
Proteins
, vol.65
, pp. 712-725
-
-
Hornak, V.1
Abel, R.2
Okur, A.3
-
41
-
-
1842479952
-
Exploring protein native states and large-scale conformational changes with a modified generalized Born model
-
1:CAS:528:DC%2BD2cXjtFKhs78%3D 10.1002/prot.20033
-
A Onufriev D Bashford DA Case 2004 Exploring protein native states and large-scale conformational changes with a modified generalized Born model Proteins 55 383 394 1:CAS:528:DC%2BD2cXjtFKhs78%3D 10.1002/prot.20033
-
(2004)
Proteins
, vol.55
, pp. 383-394
-
-
Onufriev, A.1
Bashford, D.2
Case, D.A.3
-
42
-
-
27144554995
-
Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs
-
1:CAS:528:DC%2BD2MXhtFGqtbnO 10.1111/j.1742-4658.2005.04923.x
-
Y Tie PI Boross YF Wang, et al. 2005 Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs FEBS J 272 5265 5277 1:CAS:528:DC%2BD2MXhtFGqtbnO 10.1111/j.1742-4658.2005.04923.x
-
(2005)
FEBS J
, vol.272
, pp. 5265-5277
-
-
Tie, Y.1
Boross, P.I.2
Wang, Y.F.3
-
43
-
-
45149083375
-
Effect of the active site D25N mutation on the structure, stability, and ligand binding of the mature HIV-1 protease
-
1:CAS:528:DC%2BD1cXltlGqu7g%3D 10.1074/jbc.M708506200
-
JM Sayer F Liu R Ishima, et al. 2008 Effect of the active site D25N mutation on the structure, stability, and ligand binding of the mature HIV-1 protease J Biol Chem 283 13459 13470 1:CAS:528:DC%2BD1cXltlGqu7g%3D 10.1074/jbc.M708506200
-
(2008)
J Biol Chem
, vol.283
, pp. 13459-13470
-
-
Sayer, J.M.1
Liu, F.2
Ishima, R.3
-
44
-
-
79551585231
-
How well does a restrained electrostatic potential (RESP) model perform in calcluating conformational energies of organic and biological molecules?
-
J Wang P Cieplak PA Kollman 2000 How well does a restrained electrostatic potential (RESP) model perform in calcluating conformational energies of organic and biological molecules? J Comput Chem 29 1693 1698
-
(2000)
J Comput Chem
, vol.29
, pp. 1693-1698
-
-
Wang, J.1
Cieplak, P.2
Kollman, P.A.3
-
45
-
-
46449095476
-
The generalized Born/volume integral implicit solvent model: Estimation of the free energy of hydration using London dispersion instead of atomic surface area
-
1:CAS:528:DC%2BD1cXnvFCgu7g%3D 10.1002/jcc.20933
-
P Labute 2008 The generalized Born/volume integral implicit solvent model: estimation of the free energy of hydration using London dispersion instead of atomic surface area J Comput Chem 29 1693 1698 1:CAS:528: DC%2BD1cXnvFCgu7g%3D 10.1002/jcc.20933
-
(2008)
J Comput Chem
, vol.29
, pp. 1693-1698
-
-
Labute, P.1
-
46
-
-
0026610767
-
Assessment of protein models with three-dimensional profiles
-
1:STN:280:DyaK387mvVWluw%3D%3D 10.1038/356083a0
-
R Luthy JU Bowie D Eisenberg 1992 Assessment of protein models with three-dimensional profiles Nature 356 83 85 1:STN:280:DyaK387mvVWluw%3D%3D 10.1038/356083a0
-
(1992)
Nature
, vol.356
, pp. 83-85
-
-
Luthy, R.1
Bowie, J.U.2
Eisenberg, D.3
-
47
-
-
34047224674
-
A look inside HIV resistance through retroviral protease interaction maps
-
10.1371/journal.pcbi.0030048
-
A Kontijevskis P Prusis R Petrovska, et al. 2007 A look inside HIV resistance through retroviral protease interaction maps PLoS Comput Biol 3 e48 10.1371/journal.pcbi.0030048
-
(2007)
PLoS Comput Biol
, vol.3
, pp. 48
-
-
Kontijevskis, A.1
Prusis, P.2
Petrovska, R.3
-
48
-
-
0029753776
-
Rate-determining steps in HIV-1 protease catalysis. The hydrolysis of the most specific substrate
-
1:CAS:528:DyaK2sXit1SgsA%3D%3D 10.1074/jbc.271.50.32180
-
Z Szeltner L Polgar 1996 Rate-determining steps in HIV-1 protease catalysis. The hydrolysis of the most specific substrate J Biol Chem 271 32180 32184 1:CAS:528:DyaK2sXit1SgsA%3D%3D 10.1074/jbc.271.50.32180
-
(1996)
J Biol Chem
, vol.271
, pp. 32180-32184
-
-
Szeltner, Z.1
Polgar, L.2
-
49
-
-
0025924419
-
Studies on the role of the S4 substrate binding site of HIV proteinases
-
1:CAS:528:DyaK3MXkt1Gjsrs%3D 10.1016/0014-5793(91)80186-7
-
J Tozser A Gustchina IT Weber, et al. 1991 Studies on the role of the S4 substrate binding site of HIV proteinases FEBS Lett 279 356 360 1:CAS:528:DyaK3MXkt1Gjsrs%3D 10.1016/0014-5793(91)80186-7
-
(1991)
FEBS Lett
, vol.279
, pp. 356-360
-
-
Tozser, J.1
Gustchina, A.2
Weber, I.T.3
-
50
-
-
25144487698
-
Comprehensive bioinformatic analysis of the specificity of human immunodeficiency virus type 1 protease
-
1:CAS:528:DC%2BD2MXhtVGlsL7K 10.1128/JVI.79.19.12477-12486.2005
-
L You D Garwicz T Rognvaldsson 2005 Comprehensive bioinformatic analysis of the specificity of human immunodeficiency virus type 1 protease J Virol 79 12477 12486 1:CAS:528:DC%2BD2MXhtVGlsL7K 10.1128/JVI.79.19.12477-12486.2005
-
(2005)
J Virol
, vol.79
, pp. 12477-12486
-
-
You, L.1
Garwicz, D.2
Rognvaldsson, T.3
-
52
-
-
0015441111
-
Protein volume in solution
-
10.1016/0079-6107(72)90005-3
-
AA Zamyatin 1972 Protein volume in solution Prog Biophys Mol Biol 24 107 123 10.1016/0079-6107(72)90005-3
-
(1972)
Prog Biophys Mol Biol
, vol.24
, pp. 107-123
-
-
Zamyatin, A.A.1
-
53
-
-
33645767675
-
Substrate envelope and drug resistance: Crystal structure of RO1 in complex with wild-type human immunodeficiency virus type 1 protease
-
1:CAS:528:DC%2BD28XjvFOrsb4%3D 10.1128/AAC.50.4.1518-1521.2006
-
M Prabu-Jeyabalan NM King EA Nalivaika, et al. 2006 Substrate envelope and drug resistance: crystal structure of RO1 in complex with wild-type human immunodeficiency virus type 1 protease Antimicrob Agents Chemother 50 1518 1521 1:CAS:528:DC%2BD28XjvFOrsb4%3D 10.1128/AAC.50.4.1518-1521.2006
-
(2006)
Antimicrob Agents Chemother
, vol.50
, pp. 1518-1521
-
-
Prabu-Jeyabalan, M.1
King, N.M.2
Nalivaika, E.A.3
-
54
-
-
0033581202
-
Hydrolysis mechanism of the phenylalanine-proline peptide bond specific to HIV-1 protease: Investigation by the ab initio melecular orbital method
-
1:CAS:528:DyaK1MXkslChtb0%3D 10.1021/ja9841106
-
N Okimoto T Tsukui M Hata, et al. 1999 Hydrolysis mechanism of the phenylalanine-proline peptide bond specific to HIV-1 protease: investigation by the ab initio melecular orbital method J Am Chem Soc 121 7349 7354 1:CAS:528:DyaK1MXkslChtb0%3D 10.1021/ja9841106
-
(1999)
J Am Chem Soc
, vol.121
, pp. 7349-7354
-
-
Okimoto, N.1
Tsukui, T.2
Hata, M.3
-
55
-
-
0034647235
-
Molecular dynamics study of HIV-1 protease-substrate complex: Roles of the water molecules at the loop structures of the active site
-
1:CAS:528:DC%2BD3cXjtlygtrY%3D 10.1021/ja9929178
-
N Okimoto T Tsukui K Kitayama, et al. 2000 Molecular dynamics study of HIV-1 protease-substrate complex: roles of the water molecules at the loop structures of the active site J Am Chem Soc 122 5613 5622 1:CAS:528: DC%2BD3cXjtlygtrY%3D 10.1021/ja9929178
-
(2000)
J Am Chem Soc
, vol.122
, pp. 5613-5622
-
-
Okimoto, N.1
Tsukui, T.2
Kitayama, K.3
|