-
1
-
-
0029157399
-
The not-so-great escape
-
Erickson J.W. The not-so-great escape. Nat. Struct. Biol. 2:1995;523-529
-
(1995)
Nat. Struct. Biol.
, vol.2
, pp. 523-529
-
-
Erickson, J.W.1
-
2
-
-
0028952146
-
HIV population dynamics in vivo: Implications for genetic variation, pathogenesis and therapy
-
Coffin J.M. HIV population dynamics in vivo. implications for genetic variation, pathogenesis and therapy Science. 257:1995;483-489
-
(1995)
Science
, vol.257
, pp. 483-489
-
-
Coffin, J.M.1
-
3
-
-
0024273119
-
The accuracy of reverse transcriptase from HIV-1
-
Roberts J.D., Bebenek K., Kunkel T.A. The accuracy of reverse transcriptase from HIV-1. Science. 242:1988;1171-1173
-
(1988)
Science
, vol.242
, pp. 1171-1173
-
-
Roberts, J.D.1
Bebenek, K.2
Kunkel, T.A.3
-
4
-
-
0024531983
-
Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro
-
Roberts J.D., Preston B.D., Johnston L.A., Soni A., Loeb L.A., Kunkel T.A. Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. Mol. Cell. Biol. 9:1989;469-476
-
(1989)
Mol. Cell. Biol.
, vol.9
, pp. 469-476
-
-
Roberts, J.D.1
Preston, B.D.2
Johnston, L.A.3
Soni, A.4
Loeb, L.A.5
Kunkel, T.A.6
-
5
-
-
0026536430
-
Fidelity of HIV-1 reverse transcriptase copying RNA in vitro
-
Ji J.P., Loeb L.A. Fidelity of HIV-1 reverse transcriptase copying RNA in vitro. Biochemistry. 31:1992;954-958
-
(1992)
Biochemistry
, vol.31
, pp. 954-958
-
-
Ji, J.P.1
Loeb, L.A.2
-
6
-
-
0034283345
-
How does a symmetric dimer recognize an asymmetric substrate? a substrate complex of HIV-1 protease
-
Prabu-Jeyabalan M., Nalivaika E., Schiffer C.A. How does a symmetric dimer recognize an asymmetric substrate? A substrate complex of HIV-1 protease. J. Mol. Biol. 301:2000;1207-1220
-
(2000)
J. Mol. Biol.
, vol.301
, pp. 1207-1220
-
-
Prabu-Jeyabalan, M.1
Nalivaika, E.2
Schiffer, C.A.3
-
7
-
-
0036121219
-
Substrate shape determines specificity of recognition for HIV-1 protease: Analysis of crystal structures of six substrate complexes
-
Prabu-Jeyabalan M., Nalivaika E.A., Schiffer C.A. Substrate shape determines specificity of recognition for HIV-1 protease. Analysis of crystal structures of six substrate complexes Structure. 10:2002;369-381
-
(2002)
Structure
, vol.10
, pp. 369-381
-
-
Prabu-Jeyabalan, M.1
Nalivaika, E.A.2
Schiffer, C.A.3
-
8
-
-
0029899093
-
Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors
-
Doyon L., Croteau G., Thibeault D., Poulin F., Pilote L., Lamarre D. Second locus involved in human immunodeficiency virus type 1 resistance to protease inhibitors. J. Virol. 70:1996;3763-3769
-
(1996)
J. Virol.
, vol.70
, pp. 3763-3769
-
-
Doyon, L.1
Croteau, G.2
Thibeault, D.3
Poulin, F.4
Pilote, L.5
Lamarre, D.6
-
9
-
-
0030769354
-
Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites
-
Zhang Y.M., Imamichi H., Imamichi T., Lane H.C., Falloon J., Vasudevachari M.B., Salzman N.P. Drug resistance during indinavir therapy is caused by mutations in the protease gene and in its Gag substrate cleavage sites. J. Virol. 71:1997;6662-6670
-
(1997)
J. Virol.
, vol.71
, pp. 6662-6670
-
-
Zhang, Y.M.1
Imamichi, H.2
Imamichi, T.3
Lane, H.C.4
Falloon, J.5
Vasudevachari, M.B.6
Salzman, N.P.7
-
10
-
-
0034284897
-
Polymorphism of HIV type 1 Gag p7/p1 and p1/p6 cleavage sites: Clinical significance and implications for resitance to protease inhibitors
-
Bally F., Martinez R., Peters S., Sudre P., Telenti A. Polymorphism of HIV type 1 Gag p7/p1 and p1/p6 cleavage sites. clinical significance and implications for resitance to protease inhibitors AIDS Res. Hum. Retroviruses. 16:2000;1209-1213
-
(2000)
AIDS Res. Hum. Retroviruses
, vol.16
, pp. 1209-1213
-
-
Bally, F.1
Martinez, R.2
Peters, S.3
Sudre, P.4
Telenti, A.5
-
11
-
-
0035090315
-
In vitro evolution of the human immunodeficiency virus type 1 gag-protease region and maintenance of reverse transcriptase resistance following prolonged drug exposure
-
La Seta Catamancio S., De Pasquale M.P., Citterio P., Kurtagic S., Galli M., Rusconi S. In vitro evolution of the human immunodeficiency virus type 1 gag-protease region and maintenance of reverse transcriptase resistance following prolonged drug exposure. J. Clin. Microbiol. 39:2001;1124-1129
-
(2001)
J. Clin. Microbiol.
, vol.39
, pp. 1124-1129
-
-
La Seta Catamancio, S.1
De Pasquale, M.P.2
Citterio, P.3
Kurtagic, S.4
Galli, M.5
Rusconi, S.6
-
13
-
-
0034872860
-
Current status of antiretroviral therapies
-
Temesgen Z. Current status of antiretroviral therapies. Expert Opin. Pharmacother. 2:2001;1239-1246
-
(2001)
Expert Opin. Pharmacother.
, vol.2
, pp. 1239-1246
-
-
Temesgen, Z.1
-
14
-
-
0032947107
-
Human immunodeficiency virus reverse transcriptase and protease sequence database
-
Shafer R.W., Stevenson D., Chan B. Human immunodeficiency virus reverse transcriptase and protease sequence database. Nucleic Acids Res. 27:1999;348-352
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 348-352
-
-
Shafer, R.W.1
Stevenson, D.2
Chan, B.3
-
15
-
-
0033060308
-
Identification of biased amino acid substitution patterns in human immunodeficiency virus type 1 isolates from patients treated with protease inhibitors
-
Shafer R.W., Hsu P., Patick A.K., Craig C., Brendel V. Identification of biased amino acid substitution patterns in human immunodeficiency virus type 1 isolates from patients treated with protease inhibitors. J. Virol. 73:1999;6197-6202
-
(1999)
J. Virol.
, vol.73
, pp. 6197-6202
-
-
Shafer, R.W.1
Hsu, P.2
Patick, A.K.3
Craig, C.4
Brendel, V.5
-
16
-
-
20244387096
-
Mutation patterns and structural correlates in HIV-1 protease following varying degrees of protease inhibitor treatment
-
Wu T.D., Schiffer C.A., Gonzales M.J., Taylor J., Kantor R., Chou S., Israelski D., Zolopa A.R., Fessel W.J., Shafer R.W. Mutation patterns and structural correlates in HIV-1 protease following varying degrees of protease inhibitor treatment. J. Virol. 77:2003;4836-4847
-
(2003)
J. Virol.
, vol.77
, pp. 4836-4847
-
-
Wu, T.D.1
Schiffer, C.A.2
Gonzales, M.J.3
Taylor, J.4
Kantor, R.5
Chou, S.6
Israelski, D.7
Zolopa, A.R.8
Fessel, W.J.9
Shafer, R.W.10
-
17
-
-
0037223718
-
Viability of a drug-resistant HIV-1 protease variant: Structural insights for better anti-viral therapy
-
Prabu-Jeyabalan M., Nalivaika E.A., King N.M., Schiffer C.A. Viability of a drug-resistant HIV-1 protease variant. structural insights for better anti-viral therapy J. Virol. 77:2003;1306-1315
-
(2003)
J. Virol.
, vol.77
, pp. 1306-1315
-
-
Prabu-Jeyabalan, M.1
Nalivaika, E.A.2
King, N.M.3
Schiffer, C.A.4
-
18
-
-
5444263878
-
Coevolution of the Nucleocapsid-p1 cleavage site with the V82A mutation in HIV-1 protease preserves substrate recognition
-
Prabu-Jeyabalan M., King N.M., Nalivaika E., Schiffer C.A. Coevolution of the Nucleocapsid-p1 cleavage site with the V82A mutation in HIV-1 protease preserves substrate recognition. J. Virol. in press:2004
-
(2004)
J. Virol.
-
-
Prabu-Jeyabalan, M.1
King, N.M.2
Nalivaika, E.3
Schiffer, C.A.4
-
19
-
-
5444227749
-
The structural and thermodynamic basis for the binding of a next generation HIV-1 protease inhibitor, TMC114
-
King N.M., Prabu-Jeyabalan M., Wigerinck P., De Bethune M.-P., Schiffer C.A. The structural and thermodynamic basis for the binding of a next generation HIV-1 protease inhibitor, TMC114. J. Virol. in press:2004
-
(2004)
J. Virol.
-
-
King, N.M.1
Prabu-Jeyabalan, M.2
Wigerinck, P.3
De Bethune, M.-P.4
Schiffer, C.A.5
-
20
-
-
0028846226
-
Crystal structure of HIV-1 protease in complex with VX-478, a potent and orally bioavailable inhibitor of the enzyme
-
Kim E.E., Baker C.T., Dwyer M.D., Murcko M.A., Rao B.G., Tung R.D., Navia M.A. Crystal structure of HIV-1 protease in complex with VX-478, A potent and orally bioavailable inhibitor of the enzyme. J. Am. Chem. Soc. 117:1995;1181
-
(1995)
J. Am. Chem. Soc.
, vol.117
, pp. 1181
-
-
Kim, E.E.1
Baker, C.T.2
Dwyer, M.D.3
Murcko, M.A.4
Rao, B.G.5
Tung, R.D.6
Navia, M.A.7
-
21
-
-
0027943157
-
Crystal structure at 1.9 Angstrom resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, and orally bioavailable inhibitor of the HIV proteases
-
Chen Z., Li Y., Chen E., Hall D.L., Darke P.L., Culberson C., Shafer J.A., Kuo L.C. Crystal structure at 1.9 Angstrom resolution of human immunodeficiency virus (HIV) II protease complexed with L-735,524, and orally bioavailable inhibitor of the HIV proteases. J. Biol. Chem. 269:1994;26344-26348
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 26344-26348
-
-
Chen, Z.1
Li, Y.2
Chen, E.3
Hall, D.L.4
Darke, P.L.5
Culberson, C.6
Shafer, J.A.7
Kuo, L.C.8
-
22
-
-
0026317997
-
Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere
-
Krohn A., Redshaw S., Ritchie J.C., Graves B.J., Hatada M.H. Novel binding mode of highly potent HIV-proteinase inhibitors incorporating the (R)-hydroxyethylamine isostere. J. Med. Chem. 34:1991;3340-3342
-
(1991)
J. Med. Chem.
, vol.34
, pp. 3340-3342
-
-
Krohn, A.1
Redshaw, S.2
Ritchie, J.C.3
Graves, B.J.4
Hatada, M.H.5
-
23
-
-
14444281534
-
Viracept (nelfinavir mesylate, AG1343) a potent, orally bioavailable inhibitor of HIV-1 protease
-
Kaldor S., Kalish V., Davies J.N., Shetty B., Fritz J., Appelt K., Burgess J., Campanale K., Chirgadze N., Clawson D., et al. Viracept (nelfinavir mesylate, AG1343). a potent, orally bioavailable inhibitor of HIV-1 protease J. Med. Chem. 40:1997;3979-3985
-
(1997)
J. Med. Chem.
, vol.40
, pp. 3979-3985
-
-
Kaldor, S.1
Kalish, V.2
Davies, J.N.3
Shetty, B.4
Fritz, J.5
Appelt, K.6
Burgess, J.7
Campanale, K.8
Chirgadze, N.9
Clawson, D.10
-
24
-
-
0036280264
-
X-ray crystallographic structure of ABT-378 (Lopinavir) bound to HIV-1 protease
-
Stoll V., Qin W., Stewart K.D., Jakob C., Park C., Walter K., Simmer R.L., Helfrich R., Bussiere D., Kao J., et al. X-ray crystallographic structure of ABT-378 (Lopinavir) bound to HIV-1 protease. Bioorg. Med. Chem. 10:2002;2803-2806
-
(2002)
Bioorg. Med. Chem.
, vol.10
, pp. 2803-2806
-
-
Stoll, V.1
Qin, W.2
Stewart, K.D.3
Jakob, C.4
Park, C.5
Walter, K.6
Simmer, R.L.7
Helfrich, R.8
Bussiere, D.9
Kao, J.10
-
26
-
-
0026319199
-
Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
-
Nicholls A., Sharp K., Honig B. Protein folding and association. insights from the interfacial and thermodynamic properties of hydrocarbons Proteins. 11:1991;281-296
-
(1991)
Proteins
, vol.11
, pp. 281-296
-
-
Nicholls, A.1
Sharp, K.2
Honig, B.3
|