-
1
-
-
0027202057
-
Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate. Synthesis and crystallographic analysis
-
(1993)
Biochemistry
, vol.32
, pp. 7972-7980
-
-
Abdel-Meguid, S.S.1
Zhao, B.2
Murthy, K.H.M.3
Winborne, E.4
Choi, J.-K.5
DesJarlais, R.L.6
Minnich, M.D.7
Culp, J.S.8
Debouck, C.9
Tomaszek, T.A.10
Meek, T.D.11
Dreyer, G.B.12
-
3
-
-
0029644939
-
Structure of HIV-1 protease with KNI-272, a tight-binding transition-state analog containing allophyenylnorstatine
-
(1995)
Structure
, vol.3
, pp. 581-590
-
-
Baldwin, E.T.1
Bhat, T.N.2
Guhnik, S.3
Liu, B.4
Topol, I.A.5
Kiso, Y.6
Mimoto, T.7
Mitsuya, H.8
Erickson, J.W.9
-
4
-
-
0017411710
-
The protein data bank: A computer based archival file for macromolecular structures
-
(1977)
J. Mol. Biol.
, vol.112
, pp. 535-542
-
-
Bernstein, F.C.1
Koetzle, T.F.2
Williams, G.J.3
Meyer, E.F.J.4
Brice, M.D.5
Rodgers, J.R.6
Kennerd, O.7
Shimanouchi, T.8
Tasumi, M.9
-
6
-
-
0026597444
-
The free R value: A novel statistical quantity for assessing the accuracy of crystal structures
-
(1992)
Nature
, vol.355
, pp. 472-474
-
-
Brunger, A.T.1
-
7
-
-
3543012707
-
Crystallography and NMR system: A new software suite for macromolecular structure determination
-
(1998)
Acta Crystallog. Sect. D
, vol.54
, pp. 905-921
-
-
Brunger, A.T.1
Adams, P.D.2
Clore, G.M.3
DeLano, W.L.4
Gros, P.5
Grosse-Kunstleve, R.W.6
Jiang, J.S.7
Kuszewski, J.8
Nilges, M.9
Pannu, N.S.10
Read, R.J.11
Rice, L.M.12
Simonson, T.13
Warren, G.L.14
-
9
-
-
0026663760
-
Hydroxyethylene isostere inhibitors of human immunodeficency virus-1 protease: Structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays
-
(1992)
Biochemistry
, vol.31
, pp. 6646-6659
-
-
Dreyer, G.B.1
Lambert, D.M.2
Meek, T.D.3
Carr, T.J.4
Tomaszek, J.T.A.5
Fernandez, A.V.6
Bartus, H.7
Cacciavillani, E.8
Hassel, A.M.9
Minnich, M.10
Petteway, S.R.11
Metcalf, B.W.12
-
12
-
-
0025108755
-
Crystallographic analysis of a complex between human immunodeficiency virus type 1 protease and acetyl-pepstatin at 2.0 Å resolution
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 14209-14219
-
-
Fitzgerald, P.M.1
McKeever, B.M.2
Van Middlesworth, J.F.3
Springer, J.P.4
Heimbach, J.C.5
Leu, C.T.6
Herber, W.K.7
Dixon, R.A.8
Darke, P.L.9
-
16
-
-
0028328704
-
Influence of stereochemistry on activity and binding modes of C2 symmetry-based diol inhibitors of HIV-1 protease
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 847-855
-
-
Hosur, M.V.1
Bhat, T.N.2
Kempf, D.J.3
Baldwin, E.T.4
Liu, B.5
Gulnik, S.6
Wideburg, N.E.7
Norbeck, D.W.8
Apelt, K.9
Erickson, J.W.10
-
18
-
-
0025829331
-
Structure of 2.5 Å resolution of chemically synthesized human immunodeficiency virus type 1 protease complexed with a hydroxyethylene-based inhibitor
-
(1991)
Biochemistry
, vol.30
, pp. 1600-1609
-
-
Jaskolski, M.1
Tomasselli, A.G.2
Sawyer, T.K.3
Staples, D.G.4
Heinrikson, R.L.5
Schneider, J.6
Kent, S.B.H.7
Wlodawer, A.8
-
19
-
-
0005241362
-
Active human immunodeficiency virus protease is required for viral infectivity
-
(1988)
Proc. Natl Acad. Sci. USA
, vol.85
, pp. 4686-4690
-
-
Kohl, N.E.1
Emini, E.A.2
Schleif, W.A.3
Davis, L.J.4
Heimbach, J.C.5
Dixon, R.A.6
Scolnick, E.M.7
Sigal, I.S.8
-
21
-
-
0030822601
-
Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor. Biochemistry
-
(1997)
, vol.36
, pp. 10696-10708
-
-
Laco, G.S.1
Schalk-Hihi, C.2
Lubkowski, J.3
Morris, G.4
Zdanov, A.5
Olson, A.6
Elder, J.H.7
Wlodawer, A.8
Gustchina, A.9
-
26
-
-
0033594865
-
Molecular recognition of macrocyclic peptidomimetic inhibitors by HIV-1 protease
-
(1999)
Biochemistry
, vol.38
, pp. 7978-7988
-
-
Martin, J.L.1
Begun, J.2
Schindeler, A.3
Wickramasinghe, W.A.4
Alewood, D.5
Alewood, P.F.6
Bergman, D.A.7
Brinkworth, R.I.8
Abbenante, G.9
March, D.R.10
Reid, R.C.11
Fairlie, D.P.12
-
27
-
-
0024344021
-
Structure of complex of synthetic HIV-1 protease with a substrate-based inhibitor at 2.3 Å resolution
-
(1989)
Science
, vol.246
, pp. 1149-1152
-
-
Miller, M.1
Schneider, J.2
Sathyanarayana, B.K.3
Toth, M.V.4
Marshall, G.R.5
Clawson, L.6
Selk, L.7
Kent, S.B.8
Wlodawer, A.9
-
30
-
-
0008085925
-
-
Data Collection and Processing, SerC Daresbury Laboratory, England
-
(1993)
-
-
Otwinowski, Z.1
-
33
-
-
0030939953
-
Kinetics analysis of consecutive HIV proteolytic cleavages of the Gag-Pol polyprotein
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6348-6353
-
-
Rasnick, D.1
-
35
-
-
0028969065
-
Defining the level of human immunodeficiency virus type 1 (HIV-1) protease activity required for HIV-1 particle maturation and infectivity
-
(1995)
J. Virol.
, vol.69
, pp. 2751-2758
-
-
Rose, J.R.1
Babe, L.M.2
Craik, C.S.3
-
41
-
-
0027081927
-
Crystal structure of a complex of HIV-1 protease with a dihydroxyethylene-containing inhibitor: Comparisons with molecular modeling
-
(1992)
Protein Sci.
, vol.1
, pp. 1061-1072
-
-
Thanki, N.1
Rao, J.K.M.2
Foundling, S.I.3
Howe, J.4
Moon, J.B.5
Hui, J.O.6
Tomasselli, A.G.7
Heinrikson, R.L.8
Thaisrivongs, S.9
Wlodawer, A.10
-
45
-
-
0024412506
-
Conserved folding in retroviral proteases: Crystal structure of a synthetic HIV-1 protease
-
(1989)
Science
, vol.245
, pp. 616-621
-
-
Wlodawer, A.1
Miller, M.2
Jaskolski, M.3
Sathyanarayana, B.K.4
Baldwin, E.5
Weber, I.T.6
Selk, L.M.7
Clawson, L.8
Schneider, J.9
Kent, S.B.10
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