-
1
-
-
0034064587
-
Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro
-
Allen JW, Knoblach SM, Faden AI: Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro. Cell Death Differ, 2000, 7, 470-476.
-
(2000)
Cell Death Differ
, vol.7
, pp. 470-476
-
-
Allen, J.W.1
Knoblach, S.M.2
Faden, A.I.3
-
2
-
-
0038825269
-
3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine
-
3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine). Eur J Pharmacol, 2003, 473, 35-40.
-
(2003)
Eur J Pharmacol
, vol.473
, pp. 35-40
-
-
Anderson, J.J.1
Bradbury, M.J.2
Giracello, D.R.3
Chapman, D.F.4
Holtz, G.5
Roppe, J.6
King, C.7
-
3
-
-
0036882079
-
3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl] pyridine binding to metabotropic glutamate receptor subtype 5 in rodent brain: In vitro and in vivo characterization
-
3H]Methoxymethyl-3-[(2-methyl-1,3-thiazol-4-yl)ethynyl] pyridine binding to metabotropic glutamate receptor subtype 5 in rodent brain: in vitro and in vivo characterization. J Pharmacol Exp Ther, 2002, 303, 1044-1051.
-
(2002)
J Pharmacol Exp Ther
, vol.303
, pp. 1044-1051
-
-
Anderson, J.J.1
Rao, S.P.2
Rowe, B.3
Giracello, D.R.4
Holtz, G.5
Chapman, D.F.6
Tehrani, L.7
-
4
-
-
0042536473
-
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
-
Arundine M, Tymianski M: Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium, 2003, 34, 325-337.
-
(2003)
Cell Calcium
, vol.34
, pp. 325-337
-
-
Arundine, M.1
Tymianski, M.2
-
5
-
-
0034332480
-
Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus
-
Awad H, Hubert GW, Smith Y, Levey AI, Conn PJ: Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus. J Neurosci, 2000, 20, 7871-7879.
-
(2000)
J Neurosci
, vol.20
, pp. 7871-7879
-
-
Awad, H.1
Hubert, G.W.2
Smith, Y.3
Levey, A.I.4
Conn, P.J.5
-
6
-
-
0035924328
-
Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia
-
Bao WL, Williams AJ, Faden AI, Tortella FC: Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia. Brain Res, 2001, 922, 173-179.
-
(2001)
Brain Res
, vol.922
, pp. 173-179
-
-
Bao, W.L.1
Williams, A.J.2
Faden, A.I.3
Tortella, F.C.4
-
7
-
-
0034948146
-
Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission
-
Battaglia G, Bruno V, Pisani A, Centonze D, Catania MV, Calabresi P, Nicoletti F: Selective blockade of type-1 metabotropic glutamate receptors induces neuroprotection by enhancing gabaergic transmission. Mol Cell Neurosci, 2001, 17, 1071-1083.
-
(2001)
Mol Cell Neurosci
, vol.17
, pp. 1071-1083
-
-
Battaglia, G.1
Bruno, V.2
Pisani, A.3
Centonze, D.4
Catania, M.V.5
Calabresi, P.6
Nicoletti, F.7
-
8
-
-
0037088928
-
Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity
-
Battaglia G, Fornai F, Busceti CL, Aloisi G, Cerrito F, De Blasi A, Melchiorri D, Nicoletti F: Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity. J Neurosci, 2002, 22, 2135-2141.
-
(2002)
J Neurosci
, vol.22
, pp. 2135-2141
-
-
Battaglia, G.1
Fornai, F.2
Busceti, C.L.3
Aloisi, G.4
Cerrito, F.5
De Blasi, A.6
Melchiorri, D.7
Nicoletti, F.8
-
9
-
-
0029131714
-
Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells
-
Bruno V, Copani A, Knöpfel T, Kuhn R, Casabona G, Dell'Albani P, Condorelli DF, Nicoletti F: Activation of metabotropic glutamate receptors coupled to inositol phospholipid hydrolysis amplifies NMDA-induced neuronal degeneration in cultured cortical cells. Neuropharmacology, 1995, 34, 1089-1098.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1089-1098
-
-
Bruno, V.1
Copani, A.2
Knöpfel, T.3
Kuhn, R.4
Casabona, G.5
Dell'Albani, P.6
Condorelli, D.F.7
Nicoletti, F.8
-
10
-
-
17044444317
-
Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective
-
DOI 10.1016/S0028-3908(00)00079-4, PII S0028390800000794
-
Bruno V, Ksiazek I, Battaglia G, Lukic S, Leonhardt T, Sauer D, Gasparini F et al.: Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective. Neuropharmacology, 2000, 39, 2223-2230. (Pubitemid 30642765)
-
(2000)
Neuropharmacology
, vol.39
, Issue.12
, pp. 2223-2230
-
-
Bruno, V.1
Ksiazek, I.2
Battaglia, G.3
Lukic, S.4
Leonhardt, T.5
Sauer, D.6
Gasparini, F.7
Kuhn, R.8
Nicoletti, F.9
Flor, P.J.10
-
11
-
-
3042685523
-
The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety
-
Busse CS, Brodkin J, Tattersall D, Anderson JJ, Warren N, Tehrani L, Bristow LJ et al.: The behavioral profile of the potent and selective mGlu5 receptor antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) in rodent models of anxiety. Neuropsychopharmacology, 2004, 29, 1971-1979.
-
(2004)
Neuropsychopharmacology
, vol.29
, pp. 1971-1979
-
-
Busse, C.S.1
Brodkin, J.2
Tattersall, D.3
Anderson, J.J.4
Warren, N.5
Tehrani, L.6
Bristow, L.J.7
-
12
-
-
57749093019
-
Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders
-
Review
-
Byrnes KR, Loane DJ, Faden AI: Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders. Neurotherapeutics, 2009, 6, 94-107. Review.
-
(2009)
Neurotherapeutics
, vol.6
, pp. 94-107
-
-
Byrnes, K.R.1
Loane, D.J.2
Faden, A.I.3
-
13
-
-
69249101175
-
Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents
-
Byrnes KR, Stoica B, Riccio A, Pajoohesh-Ganji A, Loane DJ, Faden AI: Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents. Ann Neurol, 2009, 66, 63-74.
-
(2009)
Ann Neurol
, vol.66
, pp. 63-74
-
-
Byrnes, K.R.1
Stoica, B.2
Riccio, A.3
Pajoohesh-Ganji, A.4
Loane, D.J.5
Faden, A.I.6
-
14
-
-
0030044058
-
Regulation of glutamate release by presynaptic kainate receptors in the hippocampus
-
Chittajallu R, Vignes MDev KK, Barnes JM, Collingridge GL, Henley JM: Regulation of glutamate release by presynaptic kainate receptors in the hippocampus. Nature, 1996, 379, 78-81.
-
(1996)
Nature
, vol.379
, pp. 78-81
-
-
Chittajallu, R.1
Vignes, M.2
Dev, K.K.3
Barnes, J.M.4
Collingridge, G.L.5
Henley, J.M.6
-
15
-
-
0026497926
-
Excitotoxic cell death
-
Choi DW: Excitotoxic cell death. J Neurobiol, 1992, 23, 1267-1276.
-
(1992)
J Neurobiol
, vol.23
, pp. 1267-1276
-
-
Choi, D.W.1
-
16
-
-
0030995878
-
Pharmacology and functions of metabotropic glutamate receptors
-
Conn PJ, Pin JP: Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol, 1997, 37, 205-237.
-
(1997)
Annu Rev Pharmacol Toxicol
, vol.37
, pp. 205-237
-
-
Conn, P.J.1
Pin, J.P.2
-
17
-
-
0037330358
-
3H]-methoxy-PEPy: Potent and selective radioligands for the metabotropic glutamate subtype 5 (mGlu5) receptor
-
3H]-methoxy- PEPy: potent and selective radioligands for the metabotropic glutamate subtype 5 (mGlu5) receptor. Bioorg Med Chem Lett, 2003, 13, 351-354.
-
(2003)
Bioorg Med Chem Lett
, vol.13
, pp. 351-354
-
-
Cosford, N.D.1
Roppe, J.2
Tehrani, L.3
Schweiger, E.J.4
Seiders, T.J.5
Chaudary, A.6
Rao, S.7
Varney, M.A.8
-
18
-
-
0037448394
-
3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: A potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity
-
DOI 10.1021/jm025570j
-
Cosford ND, Tehrani L, Roppe J, Schweiger E, Smith ND, Anderson J, Bristow L et al.: 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]-pyridine: a potent and highly selective metabotropic glutamate subtype 5 receptor antagonist with anxiolytic activity. J Med Chem, 2003, 46, 204-206. (Pubitemid 36078139)
-
(2003)
Journal of Medicinal Chemistry
, vol.46
, Issue.2
, pp. 204-206
-
-
Cosford, N.D.P.1
Tehrani, L.2
Roppe, J.3
Schweiger, E.4
Smith, N.D.5
Anderson, J.6
Bristow, L.7
Brodkin, J.8
Jiang, X.9
McDonald, I.10
Rao, S.11
Washburn, M.12
Varney, M.A.13
-
19
-
-
0020640626
-
Neurotoxic action of kainic acid
-
Coyle JT: Neurotoxic action of kainic acid. J Neurochem, 1983, 41, 1-11.
-
(1983)
J Neurochem
, vol.41
, pp. 1-11
-
-
Coyle, J.T.1
-
20
-
-
0032429754
-
Glycine and N-methyl-D-asparate receptors: Physiological significance and possible therapeutic applications
-
Danysz W, Parsons CG: Glycine and N-methyl-D-asparate receptors: physiological significance and possible therapeutic applications. Pharmacol Rev, 1998, 50, 597-664.
-
(1998)
Pharmacol Rev
, vol.50
, pp. 597-664
-
-
Danysz, W.1
Parsons, C.G.2
-
21
-
-
33846306749
-
Neuroprotective effects of MTEP, a selective mGluR5 antagonists and neuropeptide Y on the kainate-induced toxicity in primary neuronal cultures
-
Domin H, Kajta M, Śmiałowska M: Neuroprotective effects of MTEP, a selective mGluR5 antagonists and neuropeptide Y on the kainate-induced toxicity in primary neuronal cultures. Pharmacol Rep, 2006, 58, 846-858.
-
(2006)
Pharmacol Rep
, vol.58
, pp. 846-858
-
-
Domin, H.1
Kajta, M.2
Śmiałowska, M.3
-
22
-
-
0038555125
-
Characterisation of the actions of group I metabotropic glutamate receptor subtype selective ligands on excitatory amino acid release and sodium-dependent re-uptake in rat cerebrocortical minislices
-
Fazal A, Parker F, Palmer AM, Croucher MJ: Characterisation of the actions of group I metabotropic glutamate receptor subtype selective ligands on excitatory amino acid release and sodium-dependent re-uptake in rat cerebrocortical minislices. J Neurochem, 2003, 86, 1346-1358.
-
(2003)
J Neurochem
, vol.86
, pp. 1346-1358
-
-
Fazal, A.1
Parker, F.2
Palmer, A.M.3
Croucher, M.J.4
-
23
-
-
0020577545
-
Kainic acid selectively stimulates the release of endogenous excitatory acidic amino acids
-
Ferkany JW, Coyle JT: Kainic acid selectively stimulates the release of endogenous excitatory acidic amino acids. J Pharmacol Exp Ther, 1983, 225, 399-406.
-
(1983)
J Pharmacol Exp Ther
, vol.225
, pp. 399-406
-
-
Ferkany, J.W.1
Coyle, J.T.2
-
24
-
-
0019954365
-
Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors
-
Ferkany JW, Zaczek R, Coyle JT: Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors. Nature, 1982, 298, 757-759.
-
(1982)
Nature
, vol.298
, pp. 757-759
-
-
Ferkany, J.W.1
Zaczek, R.2
Coyle, J.T.3
-
25
-
-
0345894319
-
Neuroprotective activity of metabotropic glutamate receptor ligands
-
Flor PJ, Battaglia G, Nicoletti F, Gasparini F, Bruno V: Neuroprotective activity of metabotropic glutamate receptor ligands. Adv Exp Med Biol, 2002, 513, 197-223.
-
(2002)
Adv Exp Med Biol
, vol.513
, pp. 197-223
-
-
Flor, P.J.1
Battaglia, G.2
Nicoletti, F.3
Gasparini, F.4
Bruno, V.5
-
26
-
-
1642534515
-
Effect of the adenosine A2A receptor antagonist 8-(3-chlorostyryl) caffeine on L-DOPA biotransformation in rat striatum
-
Gołembiowska K, Dziubina A: Effect of the adenosine A2A receptor antagonist 8-(3-chlorostyryl)caffeine on L-DOPA biotransformation in rat striatum. Brain Res, 2004, 998, 208-217.
-
(2004)
Brain Res
, vol.998
, pp. 208-217
-
-
Gołembiowska, K.1
Dziubina, A.2
-
27
-
-
3242690678
-
2A receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats
-
2A receptor blockade increases extracellular dopamine release following l-DOPA administration in intact and dopamine-denervated rats. Neuropharmacology, 2004, 47, 414-426.
-
(2004)
Neuropharmacology
, vol.47
, pp. 414-426
-
-
Gołembiowska, K.1
Dziubina, A.2
-
28
-
-
0042698316
-
Neuroprotective action of MPEP, a selective mGluR5 antagonist, in methamphetamine-induced dopaminergic neurotoxicity is associated with a decrease in dopamine outflow and inhibition of hyperthermia in rats
-
Gołembiowska K, Konieczny J, Wolfarth S, Ossowska K: Neuroprotective action of MPEP, a selective mGluR5 antagonist, in methamphetamine-induced dopaminergic neurotoxicity is associated with a decrease in dopamine outflow and inhibition of hyperthermia in rats. Neuropharmacology, 2003, 45, 484-492.
-
(2003)
Neuropharmacology
, vol.45
, pp. 484-492
-
-
Gołembiowska, K.1
Konieczny, J.2
Wolfarth, S.3
Ossowska, K.4
-
29
-
-
84985280160
-
The efficiency of systematic sampling in stereology and its prediction
-
Gundersen HJ, Jensen EB: The efficiency of systematic sampling in stereology and its prediction. J Microsc, 1987, 147, 229-263.
-
(1987)
J Microsc
, vol.147
, pp. 229-263
-
-
Gundersen, H.J.1
Jensen, E.B.2
-
30
-
-
0141676771
-
Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury?
-
Ikonomidou C, Turski L: Why did NMDA receptor antagonists fail clinical trials for stroke and traumatic brain injury? Lancet Neurology, 2002, 1, 383-386.
-
(2002)
Lancet Neurology
, vol.1
, pp. 383-386
-
-
Ikonomidou, C.1
Turski, L.2
-
31
-
-
84984550355
-
Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats
-
Jesse CR, Savegnago L, Rocha JB, Nogueira CW: Neuroprotective effect caused by MPEP, an antagonist of metabotropic glutamate receptor mGluR5, on seizures induced by pilocarpine in 21-day-old rats. Brain Res, 2008, 1198, 197-203.
-
(2008)
Brain Res
, vol.1198
, pp. 197-203
-
-
Jesse, C.R.1
Savegnago, L.2
Rocha, J.B.3
Nogueira, C.W.4
-
32
-
-
0022802077
-
Liquid chromatographic determination of amino acids after gas-phase hydrolysis and derivatization with (dimethylamino)azobenzenesulfonyl chloride
-
Knecht R, Chang JY: Liquid chromatographic determination of amino acids after gas-phase hydrolysis and derivatization with (dimethylamino) azobenzenesulfonyl chloride. Anal Chem, 1986, 58, 2375-2379.
-
(1986)
Anal Chem
, vol.58
, pp. 2375-2379
-
-
Knecht, R.1
Chang, J.Y.2
-
33
-
-
1442275398
-
3H]R214127
-
3H]R214127. Neuropharmacology, 2004, 46, 609-619.
-
(2004)
Neuropharmacology
, vol.46
, pp. 609-619
-
-
Lavreysen, H.1
Pereira, S.N.2
Leysen, J.E.3
Langlois, X.4
Lesage, A.S.5
-
34
-
-
0345307648
-
Modulation of metabotropic glutamate receptors as potential treatment for acute and chronic neurodegenerative disorders
-
Lea IV PM, Faden AI: Modulation of metabotropic glutamate receptors as potential treatment for acute and chronic neurodegenerative disorders. Drug News Perspect, 2003, 16, 513-522.
-
(2003)
Drug News Perspect
, vol.16
, pp. 513-522
-
-
Lea IV, P.M.1
Faden, A.I.2
-
35
-
-
22044444318
-
Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors
-
Lea IV PM, Movsesyan VA, Faden AI: Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors. Br J Pharmacol, 2005, 145, 527-534.
-
(2005)
Br J Pharmacol
, vol.145
, pp. 527-534
-
-
Lea IV, P.M.1
Movsesyan, V.A.2
Faden, A.I.3
-
36
-
-
33645846952
-
Neuroprotective potential of group I metabotropic glutamate receptor antagonists in two ischemic models
-
Makarewicz D, Duszczyk M, Gadamski R, Danysz W, Łazarewicz JW: Neuroprotective potential of group I metabotropic glutamate receptor antagonists in two ischemic models. Neurochem Int, 2006, 48, 485-490.
-
(2006)
Neurochem Int
, vol.48
, pp. 485-490
-
-
Makarewicz, D.1
Duszczyk, M.2
Gadamski, R.3
Danysz, W.4
Łazarewicz, J.W.5
-
37
-
-
0031606083
-
Kainate receptors in hippocampal CA3 subregion: Evidence for a role in regulating neurotransmitter release
-
Malva JO, Carvalho AP, Carvalho CM: Kainate receptors in hippocampal CA3 subregion: evidence for a role in regulating neurotransmitter release. Neurochem Int, 1998, 32, 1-6.
-
(1998)
Neurochem Int
, vol.32
, pp. 1-6
-
-
Malva, J.O.1
Carvalho, A.P.2
Carvalho, C.M.3
-
38
-
-
34249092704
-
Calcium and neurodegeneration
-
Mattson MP: Calcium and neurodegeneration. Aging Cell, 2007, 6, 337-350.
-
(2007)
Aging Cell
, vol.6
, pp. 337-350
-
-
Mattson, M.P.1
-
39
-
-
0032562280
-
Presynaptic mGlu1 type receptors potentiate transmitter output in the rat cortex
-
Moroni F, Cozzi A, Lombardi G, Sourtcheva S, Leonardi P, Carfì M, Pellicciari R: Presynaptic mGlu1 type receptors potentiate transmitter output in the rat cortex. Eur J Pharmacol, 1998, 347, 189-195.
-
(1998)
Eur J Pharmacol
, vol.347
, pp. 189-195
-
-
Moroni, F.1
Cozzi, A.2
Lombardi, G.3
Sourtcheva, S.4
Leonardi, P.5
Carfì, M.6
Pellicciari, R.7
-
40
-
-
0035197286
-
mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6- (2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors
-
Movsesyan VA, O'Leary DM, Fan L, Bao W, Mullins PG, Knoblach SM, Faden AI: mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6- (2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors. J Pharmacol Exp Ther, 2001, 296, 41-47.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 41-47
-
-
Movsesyan, V.A.1
O'Leary, D.M.2
Fan, L.3
Bao, W.4
Mullins, P.G.5
Knoblach, S.M.6
Faden, A.I.7
-
41
-
-
0028897733
-
Clinical experience with excitatory amino acid antagonist drugs
-
Muir KW, Lees KR: Clinical experience with excitatory amino acid antagonist drugs. Stroke, 1995, 26, 503-513.
-
(1995)
Stroke
, vol.26
, pp. 503-513
-
-
Muir, K.W.1
Lees, K.R.2
-
42
-
-
0345016983
-
Distribution of mGluR1α and mGluR5 immunolabeling in primate prefrontal cortex
-
Muly EC, Maddox M, Smith Y: Distribution of mGluR1α and mGluR5 immunolabeling in primate prefrontal cortex. J Comp Neurol, 2003, 467, 521-535.
-
(2003)
J Comp Neurol
, vol.467
, pp. 521-535
-
-
Muly, E.C.1
Maddox, M.2
Smith, Y.3
-
43
-
-
0017844923
-
Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
-
Nadler JV, Perry BW, Cotman CW: Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells. Nature, 1978, 271, 676-677.
-
(1978)
Nature
, vol.271
, pp. 676-677
-
-
Nadler, J.V.1
Perry, B.W.2
Cotman, C.W.3
-
44
-
-
0032836680
-
Group-I metabotropic glutamate receptors: Hypotheses to explain their dual role in neurotoxicity and neuroprotection
-
Nicoletti F, Bruno V, Catania MV, Battaglia G, Copani A, Barbagallo G, Ceña V et al.: Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection. Neuropharmacology, 1999, 38, 1477-1484.
-
(1999)
Neuropharmacology
, vol.38
, pp. 1477-1484
-
-
Nicoletti, F.1
Bruno, V.2
Catania, M.V.3
Battaglia, G.4
Copani, A.5
Barbagallo, G.6
Ceña, V.7
-
45
-
-
0030029427
-
Metabotropic glutamate receptors: A new target for the therapy of neurodegenerative disorders?
-
Nicoletti F, Bruno V, Copani A, Casabona G, Knöpfel T: Metabotropic glutamate receptors: a new target for the therapy of neurodegenerative disorders? Trends Neurosci, 1996, 19, 267-271.
-
(1996)
Trends Neurosci
, vol.19
, pp. 267-271
-
-
Nicoletti, F.1
Bruno, V.2
Copani, A.3
Casabona, G.4
Knöpfel, T.5
-
46
-
-
0033638723
-
Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism
-
O'Leary DM, Movsesyan V, Vicini S, Faden AI: Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism. Br J Pharmacol, 2000, 131, 1429-1437.
-
(2000)
Br J Pharmacol
, vol.131
, pp. 1429-1437
-
-
O'Leary, D.M.1
Movsesyan, V.2
Vicini, S.3
Faden, A.I.4
-
47
-
-
0001933595
-
Neurotoxicity of excitatory amino acids
-
Ed. McGeer EG, Olney JW, McGeer PL, Raven Press, New York
-
Olney JW: Neurotoxicity of excitatory amino acids. In: Kainic Acid as a Tool in Neurobiology. Ed. McGeer EG, Olney JW, McGeer PL, Raven Press, New York, 1978, 95-121.
-
(1978)
Kainic Acid As a Tool in Neurobiology
, pp. 95-121
-
-
Olney, J.W.1
-
48
-
-
0002161368
-
Excitotoxic cell death
-
Ed. Koliatsos VE, Ratan RR, Humana Press, Totowa NJ
-
Olney JW, Ishimaru MJ: Excitotoxic cell death. In: Cell Death and Diseases of the Nervous System. Ed. Koliatsos VE, Ratan RR, Humana Press, Totowa NJ, 1999, 197-220.
-
(1999)
Cell Death and Diseases of the Nervous System
, pp. 197-220
-
-
Olney, J.W.1
Ishimaru, M.J.2
-
49
-
-
23844436731
-
MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats
-
Ossowska K, Konieczny J, Wolfarth S, Pilc A: MTEP, a new selective antagonist of the metabotropic glutamate receptor subtype 5 (mGluR5), produces antiparkinsonian-like effects in rats. Neuropharmacology, 2005, 49, 447-455.
-
(2005)
Neuropharmacology
, vol.49
, pp. 447-455
-
-
Ossowska, K.1
Konieczny, J.2
Wolfarth, S.3
Pilc, A.4
-
50
-
-
33747180080
-
Degeneration of dopaminergic mesocortical neurons and activation of compensatory processes induced by a long-term paraquat administration in rats: Implications for Parkinson's disease
-
Ossowska K, Śmiałowska M, Kuter K, Wieroñska J, Ziȩba B, Wardas J, Nowak P et al.: Degeneration of dopaminergic mesocortical neurons and activation of compensatory processes induced by a long-term paraquat administration in rats: implications for Parkinson's disease. Neuroscience, 2006, 141, 2155-2165.
-
(2006)
Neuroscience
, vol.141
, pp. 2155-2165
-
-
Ossowska, K.1
Śmiałowska, M.2
Kuter, K.3
Wieroñska, J.4
Ziȩba, B.5
Wardas, J.6
Nowak, P.7
-
51
-
-
26644457407
-
A slowly developing dysfunction of dopaminergic nigrostriatal neurons induced by long-term paraquat administration in rats: An animal model of preclinical stages of Parkinson's disease?
-
Ossowska K, Wardas J, Śmiałowska M, Kuter K, Lenda T, Wieroñska JM, Ziȩba B et al.: A slowly developing dysfunction of dopaminergic nigrostriatal neurons induced by long-term paraquat administration in rats: an animal model of preclinical stages of Parkinson's disease? Eur J Neurosci, 2005, 22, 1294-1304.
-
(2005)
Eur J Neurosci
, vol.22
, pp. 1294-1304
-
-
Ossowska, K.1
Wardas, J.2
Śmiałowska, M.3
Kuter, K.4
Lenda, T.5
Wieroñska, J.M.6
Ziȩba, B.7
-
52
-
-
23944453080
-
Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist
-
Pałucha A, Brañski P, Szewczyk B, Wieroñska JM, Kłak K, Pilc A: Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist. Pharmacol Biochem Behav, 2005, 81, 901-906.
-
(2005)
Pharmacol Biochem Behav
, vol.81
, pp. 901-906
-
-
Pałucha, A.1
Brañski, P.2
Szewczyk, B.3
Wieroñska, J.M.4
Kłak, K.5
Pilc, A.6
-
53
-
-
0003698235
-
-
2nd ed., Academic Press, San Diego, CA
-
Paxinos G, Watson C: The rat brain in stereotaxic coordinates, 2nd ed., Academic Press, San Diego, CA, 1986.
-
(1986)
The Rat Brain in Stereotaxic Coordinates
-
-
Paxinos, G.1
Watson, C.2
-
54
-
-
85031250379
-
The metabotropic glutamate receptors (mGluR) in neuroprotection
-
XX Winter School of the Institute of Pharmacology PAS, Mogilany. Ed. Śmiałowska M., IF PAS, Kraków
-
Pilc A: The metabotropic glutamate receptors (mGluR) in neuroprotection. In: Neuroprotection (in Polish). XX Winter School of the Institute of Pharmacology PAS, Mogilany. Ed. Śmiałowska M., IF PAS, Kraków 2003, 29-39.
-
(2003)
Neuroprotection (in Polish)
, pp. 29-39
-
-
Pilc, A.1
-
55
-
-
0034626632
-
The mGlu5 receptor agonist CHPG stimulates striatal glutamate release: Possible involvement of A2A receptors
-
Pintor A, Pèzzola A, Reggio R, Quarta D, Popoli P: The mGlu5 receptor agonist CHPG stimulates striatal glutamate release: possible involvement of A2A receptors. Neuroreport, 2000, 11, 3611-3614.
-
(2000)
Neuroreport
, vol.11
, pp. 3611-3614
-
-
Pintor, A.1
Pèzzola, A.2
Reggio, R.3
Quarta, D.4
Popoli, P.5
-
56
-
-
0035959976
-
Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons
-
Pisani A, Gubellini P, Bonsi P, Conquet F, Picconi B, Centonze D, Bernardi G, Calabresi P: Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons. Neuroscience, 2001, 106, 579-587.
-
(2001)
Neuroscience
, vol.106
, pp. 579-587
-
-
Pisani, A.1
Gubellini, P.2
Bonsi, P.3
Conquet, F.4
Picconi, B.5
Centonze, D.6
Bernardi, G.7
Calabresi, P.8
-
57
-
-
3042522901
-
Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: Involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity
-
Popoli P, Pintor A, Tebano MT, Frank C, Pepponi R, Nazzicone V, Grieco R et al.: Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity. J Neurochem, 2004, 89, 1479-1489.
-
(2004)
J Neurochem
, vol.89
, pp. 1479-1489
-
-
Popoli, P.1
Pintor, A.2
Tebano, M.T.3
Frank, C.4
Pepponi, R.5
Nazzicone, V.6
Grieco, R.7
-
58
-
-
0034693412
-
Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil
-
Rao AM, Hatcher JF, Dempsey RJ: Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil. Neurosci Lett, 2000, 293, 1-4.
-
(2000)
Neurosci Lett
, vol.293
, pp. 1-4
-
-
Rao, A.M.1
Hatcher, J.F.2
Dempsey, R.J.3
-
59
-
-
0029002053
-
Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain
-
Romano C, Sesma MA, McDonald CT, O'Malley K, Van den Pol AN, Olney JW: Distribution of metabotropic glutamate receptor mGluR5 immunoreactivity in rat brain. J Comp Neurol, 1995, 355, 455-469.
-
(1995)
J Comp Neurol
, vol.355
, pp. 455-469
-
-
Romano, C.1
Sesma, M.A.2
McDonald, C.T.3
O'Malley, K.4
Van Den Pol, A.N.5
Olney, J.W.6
-
60
-
-
0026716350
-
Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: An in situ hybridization study in adult and developing rat
-
Shigemoto R, Nakanishi S, Mizuno N: Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat. J Comp Neurol, 1992, 322, 121-135.
-
(1992)
J Comp Neurol
, vol.322
, pp. 121-135
-
-
Shigemoto, R.1
Nakanishi, S.2
Mizuno, N.3
-
61
-
-
0027378595
-
Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain
-
DOI 10.1016/0304-3940(93)90227-C
-
Shigemoto R, Nomura S, Ohishi H, Sugihara H, Nakanishi S, Mizuno N: Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain. Neurosci Lett, 1993, 163, 53-57. (Pubitemid 23349393)
-
(1993)
Neuroscience Letters
, vol.163
, Issue.1
, pp. 53-57
-
-
Shigemoto, R.1
Nomura, S.2
Ohishi, H.3
Sugihara, H.4
Nakanishi, S.5
Mizuno, N.6
-
62
-
-
0032983086
-
Antidepressants for the new millennium
-
Skolnick P: Antidepressants for the new millennium. Eur J Pharmacol, 1999, 375, 31-40.
-
(1999)
Eur J Pharmacol
, vol.375
, pp. 31-40
-
-
Skolnick, P.1
-
63
-
-
0037025273
-
The pharmacological manipulation of glutamate receptors and neuroprotection
-
Stone TW, Addae JI: The pharmacological manipulation of glutamate receptors and neuroprotection. Eur J Pharmacol, 2002, 447, 285-296.
-
(2002)
Eur J Pharmacol
, vol.447
, pp. 285-296
-
-
Stone, T.W.1
Addae, J.I.2
-
64
-
-
33751420737
-
Neuroprotective activity of selective mGlu1 and mGlu5 antagonists in vitro and in vivo
-
Szydlowska K, Kaminska B, Baude A, Parsons CG, Danysz W: Neuroprotective activity of selective mGlu1 and mGlu5 antagonists in vitro and in vivo. Eur J Pharmacol, 2007, 554, 18-29.
-
(2007)
Eur J Pharmacol
, vol.554
, pp. 18-29
-
-
Szydlowska, K.1
Kaminska, B.2
Baude, A.3
Parsons, C.G.4
Danysz, W.5
-
65
-
-
67349261064
-
Neuroprotective effects of neuropeptide Y-Y2 and Y5 receptor agonists in vitro and in vivo
-
Śmiałowska M, Domin H, Ziȩba B, Koźniewska E, Michalik R, Piotrowski P, Kajta M: Neuroprotective effects of neuropeptide Y-Y2 and Y5 receptor agonists in vitro and in vivo. Neuropeptides, 2009, 43, 235-249.
-
(2009)
Neuropeptides
, vol.43
, pp. 235-249
-
-
Śmiałowska, M.1
Domin, H.2
Ziȩba, B.3
Koźniewska, E.4
Michalik, R.5
Piotrowski, P.6
Kajta, M.7
-
66
-
-
18544401319
-
Neuroprotective effect of NPY on kainate neurotoxicity in the hippocampus
-
Śmiałowska M, Wieroñska JM, Szewczyk B: Neuroprotective effect of NPY on kainate neurotoxicity in the hippocampus. Pol J Pharmacol, 2003, 55, 979-986.
-
(2003)
Pol J Pharmacol
, vol.55
, pp. 979-986
-
-
Śmiałowska, M.1
Wieroñska, J.M.2
Szewczyk, B.3
-
67
-
-
0034861333
-
5 receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP): Complementary in vitro and in vivo evidence
-
5 receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP): complementary in vitro and in vivo evidence. Neuropharmacology, 2001, 41, 523-527.
-
(2001)
Neuropharmacology
, vol.41
, pp. 523-527
-
-
Thomas, L.S.1
Jane, D.E.2
Gasparini, F.3
Croucher, M.J.4
-
69
-
-
0032874391
-
Potentiation of NMDA and AMPA responses by the specific mGluR5 agonist CHPG in spinal cord motoneurons
-
Ugolini A, Corsi M, Bordi F: Potentiation of NMDA and AMPA responses by the specific mGluR5 agonist CHPG in spinal cord motoneurons. Neuropharmacology, 1999, 38, 1569-1576.
-
(1999)
Neuropharmacology
, vol.38
, pp. 1569-1576
-
-
Ugolini, A.1
Corsi, M.2
Bordi, F.3
-
70
-
-
26944465351
-
Neuroprotective effects of metabotropic glutamate receptor ligands in a 6-hydroxydopamine rodent model of Parkinson's disease
-
Vernon AC, Palmer S, Datla KP, Zbarsky V, Croucher MJ, Dexter DT: Neuroprotective effects of metabotropic glutamate receptor ligands in a 6-hydroxydopamine rodent model of Parkinson's disease. Eur J Neurosci, 2005, 22, 1799-1806.
-
(2005)
Eur J Neurosci
, vol.22
, pp. 1799-1806
-
-
Vernon, A.C.1
Palmer, S.2
Datla, K.P.3
Zbarsky, V.4
Croucher, M.J.5
Dexter, D.T.6
|