Characterisation of the actions of group I metabotropic glutamate receptor subtype selective ligands on excitatory amino acid release and sodium-dependent re-uptake in rat cerebrocortical minislices

Journal of Neurochemistry

Volumn 86, Issue 6, 2003, Pages 1346-1358

  Fazal, Abidali ^a   Parker, Fred ^b   Palmer, Alan M ^c   Croucher, Martin J ^a  

^a CHARING CROSS HOSPITAL   (United Kingdom)

^b Vernalis PLC   (United Kingdom)

^c Pharmidex   (United Kingdom)

Author keywords

Cerebral cortex; Excitatory amino acid release; Excitatory amino acid uptake; Facilitation; Group I mGlu receptors; Pre synaptic

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 1 AMINO 1,5 INDANDICARBOXYLIC ACID; 2 CHLORO 5 HYDROXYPHENYLGLYCINE; 2 METHYL 6 (PHENYLETHYNYL)PYRIDINE; 2,4 PYRROLIDINEDICARBOXYLIC ACID; 3 BENZYLOXYASPARTATE; 3,5 DIHYDROXYPHENYLGLYCINE; 4 CARBOXY 2 METHYLPHENYLGLYCINE; 6 METHYL 2 PHENYLAZO 3 PYRIDINOL; ALPHA METHYL 4 CARBOXYPHENYLGLYCINE; ASPARTIC ACID; ASPARTIC ACID DERIVATIVE; EXCITATORY AMINO ACID; GLUTAMATE RECEPTOR ANTAGONIST; METABOTROPIC GLUTAMATE RECEPTOR 1 AGONIST; METABOTROPIC GLUTAMATE RECEPTOR 1 ANTAGONIST; METABOTROPIC GLUTAMATE RECEPTOR 5 AGONIST; METABOTROPIC GLUTAMATE RECEPTOR 6 ANTAGONIST; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR AGONIST; NEUROPROTECTIVE AGENT; POTASSIUM ION; SODIUM ION; TRITIUM; UNCLASSIFIED DRUG;

AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN SLICE; CONCENTRATION RESPONSE; DRUG BIOAVAILABILITY; DRUG MECHANISM; DRUG POTENCY; FACILITATION; IC 50; MALE; NERVE ENDING; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BINDING, COMPETITIVE; BIOLOGICAL TRANSPORT; CEREBRAL CORTEX; D-ASPARTIC ACID; EXCITATORY AMINO ACID AGONISTS; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY AMINO ACIDS; GLYCINE; LIGANDS; MALE; POTASSIUM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; RESORCINOLS; SODIUM; TRITIUM;

ANIMALIA;

EID: 0038555125     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2003.01932.x     Document Type: Article

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