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Volumn 54, Issue 5, 2010, Pages 500-509

Hypoxia PET/CT imaging: Implications for radiation oncology

Author keywords

Cell hypoxia; Neoplasms; Radiation

Indexed keywords

2 (2 NITRO 1H IMIDAZOL 1 YL) N (2,2,3,3,3 PENTAFLUOROPROPYL)ACETAMIDE; COPPER DERIVATIVE; ETANIDAZOLE; FLUORODEOXYGLUCOSE F 18; FLUOROETANIDAZOLE; MISONIDAZOLE; NITROIMIDAZOLE DERIVATIVE; PIMONIDAZOLE; RADIOPHARMACEUTICAL AGENT; RADIOSENSITIZING AGENT; UNCLASSIFIED DRUG;

EID: 79251481188     PISSN: 18244785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (23)

References (100)
  • 1
    • 0025913227 scopus 로고
    • Oxygen in mammalian tissue: Methods of measurement and affinities of various reactions
    • Vanderkooi JM, Erecinska M, Silver IA. Oxygen in mammalian tissue: methods of measurement and affinities of various reactions. Am J Physiol 1991;260(6 Pt 1):C1131-50.
    • (1991) Am J Physiol , vol.260 , Issue.6 PART 1
    • Vanderkooi, J.M.1    Erecinska, M.2    Silver, I.A.3
  • 2
    • 0024598020 scopus 로고
    • Oxygen delivery and uptake by peripheral tissues: Physiology and pathophysiology
    • Schumacker PT, Samsel RW. Oxygen delivery and uptake by peripheral tissues: physiology and pathophysiology. Crit Care Clin 1989;5:255-69.
    • (1989) Crit Care Clin , vol.5 , pp. 255-269
    • Schumacker, P.T.1    Samsel, R.W.2
  • 3
    • 0006718386 scopus 로고    scopus 로고
    • Introducing fluorine-18 fluoromisonidazole positron emission tomography for the localisation and quantification of pig liver hypoxia
    • Piert M, Machulla H, Becker G, Stahlschmidt A, Patt M, Aldinger P et al. Introducing fluorine-18 fluoromisonidazole positron emission tomography for the localisation and quantification of pig liver hypoxia. Eur J Nucl Med 1999;26.95-109.
    • (1999) Eur J Nucl Med , vol.26 , pp. 95-109
    • Piert, M.1    Machulla, H.2    Becker, G.3    Stahlschmidt, A.4    Patt, M.5    Aldinger, P.6
  • 4
    • 0034353130 scopus 로고    scopus 로고
    • Dependency of the [18F]fluoromisonidazole uptake on oxygen delivery and tissue oxygenation in the porcine liver
    • Piert M, Machulla HJ, Becker G, Aldinger P, Winter E, Bares R. Dependency of the [18F]fluoromisonidazole uptake on oxygen delivery and tissue oxygenation in the porcine liver. Nucl Med Biol 2000;27:693-700.
    • (2000) Nucl Med Biol , vol.27 , pp. 693-700
    • Piert, M.1    Machulla, H.J.2    Becker, G.3    Aldinger, P.4    Winter, E.5    Bares, R.6
  • 6
    • 0026468180 scopus 로고
    • A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
    • Semenza GL, Wang GL. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Mol Cell Biol 1992;12:5447-54.
    • (1992) Mol Cell Biol , vol.12 , pp. 5447-5454
    • Semenza, G.L.1    Wang, G.L.2
  • 7
    • 69549138474 scopus 로고    scopus 로고
    • Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events
    • Lehmann S, Stiehl DP, Honer M, Dominietto M, Keist R, Kotevic I et al. Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events. Proc Natl Acad Sci U S A 2009;106:14004-9.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 14004-14009
    • Lehmann, S.1    Stiehl, D.P.2    Honer, M.3    Dominietto, M.4    Keist, R.5    Kotevic, I.6
  • 8
    • 0032033086 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis
    • Semenza GL. Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis. J Lab Clin Med 1998;131:207-14.
    • (1998) J Lab Clin Med , vol.131 , pp. 207-214
    • Semenza, G.L.1
  • 9
    • 3142587028 scopus 로고    scopus 로고
    • Tumor microenvironmental physiology and its implications for radiation oncology
    • Vaupel P. Tumor microenvironmental physiology and its implications for radiation oncology. Semin Radiat Oncol 2004;14:198-206.
    • (2004) Semin Radiat Oncol , vol.14 , pp. 198-206
    • Vaupel, P.1
  • 10
    • 0032502641 scopus 로고    scopus 로고
    • Effect of adenosine receptor agonists on release of the nucleoside analogue [3H]formycin B from cultured smooth muscle DDT1 MF-2 cells
    • Borgland SL, Parkinson FE. Effect of adenosine receptor agonists on release of the nucleoside analogue [3H]formycin B from cultured smooth muscle DDT1 MF-2 cells. Eur J Pharmacol 1998;346:339-44.
    • (1998) Eur J Pharmacol , vol.346 , pp. 339-344
    • Borgland, S.L.1    Parkinson, F.E.2
  • 11
    • 0034989311 scopus 로고    scopus 로고
    • Biological consequences of tumor hypoxia
    • Hockel M, Vaupel P. Biological consequences of tumor hypoxia. Semin Oncol 2001;28(2 Suppl 8):36-41.
    • (2001) Semin Oncol , vol.28 , Issue.2 SUPPL. 8 , pp. 36-41
    • Hockel, M.1    Vaupel, P.2
  • 12
    • 0036216692 scopus 로고    scopus 로고
    • HIF-1 and tumor progression: Pathophysiology and therapeutics
    • Semenza GL. HIF-1 and tumor progression: pathophysiology and therapeutics. Trends Mol Med 2002;8(4 Suppl):S62-7.
    • (2002) Trends Mol Med , vol.8 , Issue.4 SUPPL.
    • Semenza, G.L.1
  • 14
    • 0033790531 scopus 로고    scopus 로고
    • Tumor hypoxia and anemia: Impact on the efficacy of radiation therapy
    • Kumar P. Tumor hypoxia and anemia: impact on the efficacy of radiation therapy. Semin Hematol 2000;37(4 Suppl 6):4-8.
    • (2000) Semin Hematol , vol.37 , Issue.4 SUPPL. 6 , pp. 4-8
    • Kumar, P.1
  • 15
    • 66149110742 scopus 로고    scopus 로고
    • Enhancing radiosensitivity: Targeting the DNA repair pathways
    • Jorgensen TJ. Enhancing radiosensitivity: targeting the DNA repair pathways. Cancer Biol Ther 2009;8:665-70.
    • (2009) Cancer Biol Ther , vol.8 , pp. 665-670
    • Jorgensen, T.J.1
  • 16
    • 47949088666 scopus 로고    scopus 로고
    • Clinical target promiscuity: Lessons from ras molecular trials
    • Rengan R, Cengel KA, Hahn SM. Clinical target promiscuity: lessons from ras molecular trials. Cancer Metastasis Rev 2008;27:403-14.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 403-414
    • Rengan, R.1    Cengel, K.A.2    Hahn, S.M.3
  • 17
    • 34547121206 scopus 로고    scopus 로고
    • Hypoxia in cancer: Significance and impact on clinical outcome
    • DOI 10.1007/s10555-007-9055-1, Special issue on Hypoxia and Cancer, Guest Editor: Gregg L. Semenza
    • Vaupel P, Mayer A. Hypoxia in cancer: significance and impact on clinical outcome. Cancer Metastasis Rev 2007;26:225-39. (Pubitemid 47101660)
    • (2007) Cancer and Metastasis Reviews , vol.26 , Issue.2 , pp. 225-239
    • Vaupel, P.1    Mayer, A.2
  • 18
    • 0027379128 scopus 로고
    • Intrinsic radiosensitivity and prediction of patient response to radiotherapy for carcinoma of the cervix
    • West CM, Davidson SE, Roberts SA, Hunter RD. Intrinsic radiosensitivity and prediction of patient response to radiotherapy for carcinoma of the cervix. Br J Cancer 1993;68:819-23.
    • (1993) Br J Cancer , vol.68 , pp. 819-823
    • West, C.M.1    Davidson, S.E.2    Roberts, S.A.3    Hunter, R.D.4
  • 20
    • 0021723471 scopus 로고
    • Reduced oxygen enhancement ratio at low doses of ionizing radiation
    • Palcic B, Skarsgard LD. Reduced oxygen enhancement ratio at low doses of ionizing radiation. Radiat Res 1984;100:328-39.
    • (1984) Radiat Res , vol.100 , pp. 328-339
    • Palcic, B.1    Skarsgard, L.D.2
  • 22
    • 0033927677 scopus 로고    scopus 로고
    • Apoptosis and cancer chemotherapy
    • Makin G, Hickman JA. Apoptosis and cancer chemotherapy. Cell Tissue Res 2000;301:143-52.
    • (2000) Cell Tissue Res , vol.301 , pp. 143-152
    • Makin, G.1    Hickman, J.A.2
  • 24
    • 0029844596 scopus 로고    scopus 로고
    • Direct measurements of tumor-tissue pO2. A way of selecting patients for hyperoxic treatment
    • Nordsmark M. Direct measurements of tumor-tissue pO2. A way of selecting patients for hyperoxic treatment. Strahlenther Onkol 1996;172 Suppl 2:8-9.
    • (1996) Strahlenther Onkol , vol.172 , Issue.SUPPL. 2 , pp. 8-9
    • Nordsmark, M.1
  • 26
    • 44149092895 scopus 로고    scopus 로고
    • Hypoxia in prostate cancer: A powerful shield against tumour destruction?
    • Marignol L, Coffey M, Lawler M, Hollywood D. Hypoxia in prostate cancer: a powerful shield against tumour destruction? Cancer Treat Rev 2008;34:313-27.
    • (2008) Cancer Treat Rev , vol.34 , pp. 313-327
    • Marignol, L.1    Coffey, M.2    Lawler, M.3    Hollywood, D.4
  • 27
    • 0035917618 scopus 로고    scopus 로고
    • Hypoxia in human soft tissue sarcomas: Adverse impact on survival and no association with p53 mutations
    • Nordsmark M, Alsner J, Keller J, Nielsen OS, Jensen OM, Horsman MR et al. Hypoxia in human soft tissue sarcomas: adverse impact on survival and no association with p53 mutations. Br J Cancer 2001;84:1070-5.
    • (2001) Br J Cancer , vol.84 , pp. 1070-1075
    • Nordsmark, M.1    Alsner, J.2    Keller, J.3    Nielsen, O.S.4    Jensen, O.M.5    Horsman, M.R.6
  • 28
    • 33751277287 scopus 로고    scopus 로고
    • CA IX is an independent prognostic marker in premenopausal breast cancer patients with one to three positive lymph nodes and a putative marker of radiation resistance
    • DOI 10.1158/1078-0432.CCR-06-0480
    • Brennan DJ, Jirstrom K, Kronblad A, Millikan RC, Landberg G, Duffy MJ et al. CA LX is an independent prognostic marker in premenopausal breast cancer patients with one to three positive lymph nodes and a putative marker of radiation resistance. Clin Cancer Res 2006;12:6421-31. (Pubitemid 44799714)
    • (2006) Clinical Cancer Research , vol.12 , Issue.21 , pp. 6421-6431
    • Brennan, D.J.1    Jirstrom, K.2    Kronblad, A.3    Millikan, R.C.4    Landberg, G.5    Duffy, M.J.6    Ryden, L.7    Gallagher, W.M.8    O'Brien, S.L.9
  • 29
  • 30
    • 33644849887 scopus 로고    scopus 로고
    • Endogenous markers of two separate hypoxia response pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) are associated with radiotherapy failure in head and neck cancer patients recruited in the CHART randomized trial
    • Koukourakis MI, Bentzen SM, Giatromanolaki A, Wilson GD, Daley FM, Saunders MI et al. Endogenous markers of two separate hypoxia response pathways (hypoxia inducible factor 2 alpha and carbonic anhydrase 9) are associated with radiotherapy failure in head and neck cancer patients recruited in the CHART randomized trial. J Clin Oncol 2006;24:727-35.
    • (2006) J Clin Oncol , vol.24 , pp. 727-735
    • Koukourakis, M.I.1    Bentzen, S.M.2    Giatromanolaki, A.3    Wilson, G.D.4    Daley, F.M.5    Saunders, M.I.6
  • 32
    • 42049121462 scopus 로고    scopus 로고
    • Intratumoral Spatial Distribution of Hypoxia and Angiogenesis Assessed by 18F-FAZA and 125I-Gluco-RGD Autoradiography
    • Picchio M, Beck R, Haubner R, Seidl S, Machulla HJ, Johnson TD et al. Intratumoral Spatial Distribution of Hypoxia and Angiogenesis Assessed by 18F-FAZA and 125I-Gluco-RGD Autoradiography. J Nucl Med 2008;49:597-605.
    • (2008) J Nucl Med , vol.49 , pp. 597-605
    • Picchio, M.1    Beck, R.2    Haubner, R.3    Seidl, S.4    Machulla, H.J.5    Johnson, T.D.6
  • 33
    • 46749143345 scopus 로고    scopus 로고
    • Molecular imaging of hypoxia
    • Krohn KA, Link JM, Mason RP. Molecular imaging of hypoxia. J Nucl Med 2008;49 Suppl 2:129S-48S.
    • (2008) J Nucl Med , vol.49 , Issue.SUPPL. 2
    • Krohn, K.A.1    Link, J.M.2    Mason, R.P.3
  • 34
    • 77049163478 scopus 로고
    • A new antibiotic, azomycin
    • Tokyo
    • Maeda K, Osato T, Umezawa H. A new antibiotic, azomycin. J Antibiot (Tokyo) 1953;6:182.
    • (1953) J Antibiot , vol.6 , pp. 182
    • Maeda, K.1    Osato, T.2    Umezawa, H.3
  • 35
    • 0035869722 scopus 로고    scopus 로고
    • A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy
    • Chao KS, Bosch WR, Mutic S, Lewis JS, Dehdashti F, Mintun MA et al. A novel approach to overcome hypoxic tumor resistance: Cu-ATSM-guided intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 2001;49:1171-82.
    • (2001) Int J Radiat Oncol Biol Phys , vol.49 , pp. 1171-1182
    • Chao, K.S.1    Bosch, W.R.2    Mutic, S.3    Lewis, J.S.4    Dehdashti, F.5    Mintun, M.A.6
  • 36
    • 0018635742 scopus 로고
    • Hypoxic sensitizers - Implications for radiation therapy
    • Chapman JD. Hypoxic sensitizers - implications for radiation therapy. N Engl J Med 1979;301:1429-32.
    • (1979) N Engl J Med , vol.301 , pp. 1429-1432
    • Chapman, J.D.1
  • 37
    • 0004974884 scopus 로고
    • Molecular interactions and biological effects of the products of reduction of nitroimidazoles
    • Adams GE, Breccia A, Fiedlen EN, Wardman P, eds. New York: Plenum Press
    • Mc Clelland RA. Molecular interactions and biological effects of the products of reduction of nitroimidazoles. In: Adams GE, Breccia A, Fiedlen EN, Wardman P, eds. NATO Advanced Research Workshop on Selective Activation of Drugs by Redox Processes. New York: Plenum Press; 1990:125-36.
    • (1990) NATO Advanced Research Workshop on Selective Activation of Drugs by Redox Processes , pp. 125-136
    • Mc Clelland, R.A.1
  • 39
    • 34848893337 scopus 로고    scopus 로고
    • Hypoxia positron emission tomography imaging with 18F-Fluoromisonidazole
    • Lee ST, Scott AM. Hypoxia positron emission tomography imaging with 18F-Fluoromisonidazole. Semin Nucl Med 2007;37:451-61.
    • (2007) Semin Nucl Med , vol.37 , pp. 451-461
    • Lee, S.T.1    Scott, A.M.2
  • 42
    • 34547984111 scopus 로고    scopus 로고
    • 18F] fluorodeoxyglucose positron emission tomography: Validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia?
    • 18F] fluorodeoxyglucose positron emission tomography: validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia? BMC Cancer 2007;7:113.
    • (2007) BMC Cancer , vol.7 , pp. 113
    • Gagel, B.1    Piroth, M.2    Reinartz, P.3    Zimmy, M.4    Kaiser, H.J.5
  • 43
    • 0030249455 scopus 로고    scopus 로고
    • Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: A pretherapy study of 37 patients
    • Rasey J, Koh W, Evans M, Peterson L, Lewellen T, Graham M et al. Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: a pretherapy study of 37 patients. Int J Radiat Oncol Biol Phys 1996;24:417-28.
    • (1996) Int J Radiat Oncol Biol Phys , vol.24 , pp. 417-428
    • Rasey, J.1    Koh, W.2    Evans, M.3    Peterson, L.4    Lewellen, T.5    Graham, M.6
  • 45
    • 52049120148 scopus 로고    scopus 로고
    • Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: Correlation with time to progression and survival
    • Spence AM, Muzi M, Swanson KR, O'Sullivan F, Rockhill JK, Rajendran JG et al. Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: correlation with time to progression and survival. Clin Cancer Res 2008;14:2623-30.
    • (2008) Clin Cancer Res , vol.14 , pp. 2623-2630
    • Spence, A.M.1    Muzi, M.2    Swanson, K.R.3    O'Sullivan, F.4    Rockhill, J.K.5    Rajendran, J.G.6
  • 48
  • 51
    • 11144357375 scopus 로고    scopus 로고
    • Comparison of the biodistribution of two hypoxia markers [18F]FETNIM and [18F]FMISO in an experimental mammary carcinoma
    • Gronroos T, Bentzen L, Marjamaki P, Murata R, Horsman MR, Keiding S et al. Comparison of the biodistribution of two hypoxia markers [18F]FETNIM and [18F]FMISO in an experimental mammary carcinoma. Eur J Nucl Med Mol Imaging 2004;31:513-20.
    • (2004) Eur J Nucl Med Mol Imaging , vol.31 , pp. 513-520
    • Gronroos, T.1    Bentzen, L.2    Marjamaki, P.3    Murata, R.4    Horsman, M.R.5    Keiding, S.6
  • 54
  • 57
    • 34249313652 scopus 로고    scopus 로고
    • Imaging of tumor hypoxia with [124I]IAZA in comparison with [18F]FMISO and [18F]FAZA - First small animal PET results
    • Reischl G, Dorow DS, Cullinane C, Katsifis A, Roselt P, Binns D et al. Imaging of tumor hypoxia with [124I]IAZA in comparison with [18F]FMISO and [18F]FAZA - first small animal PET results. J Pharm Pharm Sci 2007;10:203-11.
    • (2007) J Pharm Pharm Sci , vol.10 , pp. 203-211
    • Reischl, G.1    Dorow, D.S.2    Cullinane, C.3    Katsifis, A.4    Roselt, P.5    Binns, D.6
  • 60
    • 70350532485 scopus 로고    scopus 로고
    • Initial results of hypoxia imaging using 1-alpha-D: -(5-deoxy-5-[(18)F]- fluoroarabinofuranosyl)-2-nitroimidazole ((18)F-FAZA)
    • Epub ahead of print
    • Postema EJ, McEwan AJ, Riauka TA, Kumar P, Richmond DA, Abrams DN et al. Initial results of hypoxia imaging using 1-alpha-D: -(5-deoxy-5-[(18)F]- fluoroarabinofuranosyl)-2-nitroimidazole ((18)F-FAZA). Eur J Nucl Med Mol Imaging 2009 [Epub ahead of print].
    • (2009) Eur J Nucl Med Mol Imaging
    • Postema, E.J.1    McEwan, A.J.2    Riauka, T.A.3    Kumar, P.4    Richmond, D.A.5    Abrams, D.N.6
  • 61
    • 0030811565 scopus 로고    scopus 로고
    • Copper-62-ATSM: A new hypoxia imaging agent with high membrane permeability and low redox potential
    • Fujibayashi Y, Taniuchi H, Yonekura Y, Ohtani H, Konishi J, Yokoyama A. Copper-62-ATSM: a new hypoxia imaging agent with high membrane permeability and low redox potential. J Nucl Med 1997;38:1155-60.
    • (1997) J Nucl Med , vol.38 , pp. 1155-1160
    • Fujibayashi, Y.1    Taniuchi, H.2    Yonekura, Y.3    Ohtani, H.4    Konishi, J.5    Yokoyama, A.6
  • 62
    • 0036943656 scopus 로고    scopus 로고
    • Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: Structure-activity relationships
    • Dearling JL, Lewis JS, Mullen GE, Welch MJ, Blower PJ. Copper bis(thiosemicarbazone) complexes as hypoxia imaging agents: structure-activity relationships. J Biol Inorg Chem 2002;7:249-59.
    • (2002) J Biol Inorg Chem , vol.7 , pp. 249-259
    • Dearling, J.L.1    Lewis, J.S.2    Mullen, G.E.3    Welch, M.J.4    Blower, P.J.5
  • 64
    • 69449094645 scopus 로고    scopus 로고
    • Assessing tumor hypoxia by positron emission tomography with Cu-ATSM
    • Holland JP, Lewis JS, Dehdashti F. Assessing tumor hypoxia by positron emission tomography with Cu-ATSM. Q J Nucl Med Mol Imaging 2009;53:193-200.
    • (2009) Q J Nucl Med Mol Imaging , vol.53 , pp. 193-200
    • Holland, J.P.1    Lewis, J.S.2    Dehdashti, F.3
  • 65
    • 20144387807 scopus 로고    scopus 로고
    • Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models
    • O'Donoghue JA, Zanzonico P, Pugachev A, Wen B, Smith-Jones P, Cai S et al. Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models. Int J Radiat Oncol Biol Phys 2005;61:1493-502.
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , pp. 1493-1502
    • O'Donoghue, J.A.1    Zanzonico, P.2    Pugachev, A.3    Wen, B.4    Smith-Jones, P.5    Cai, S.6
  • 67
    • 17444408174 scopus 로고    scopus 로고
    • Imaging of melanoma using 64Cu- and 86Y-DOTA-ReCCMSH(Arg11), a cyclized peptide analogue of alpha-MSH
    • McQuade P, Miao Y, Yoo J, Quinn TP, Welch MJ, Lewis JS. Imaging of melanoma using 64Cu- and 86Y-DOTA-ReCCMSH(Arg11), a cyclized peptide analogue of alpha-MSH. J Med Chem 2005;48:2985-92.
    • (2005) J Med Chem , vol.48 , pp. 2985-2992
    • McQuade, P.1    Miao, Y.2    Yoo, J.3    Quinn, T.P.4    Welch, M.J.5    Lewis, J.S.6
  • 71
    • 53649095183 scopus 로고    scopus 로고
    • Hyperbaric oxygenation for tumour sensitisation to radiotherapy: A systematic review of randomised controlled trials
    • Bennett M, Feldmeier J, Smee R, Milross C. Hyperbaric oxygenation for tumour sensitisation to radiotherapy: a systematic review of randomised controlled trials. Cancer Treat Rev 2008;34:577-91.
    • (2008) Cancer Treat Rev , vol.34 , pp. 577-591
    • Bennett, M.1    Feldmeier, J.2    Smee, R.3    Milross, C.4
  • 73
    • 0031661074 scopus 로고    scopus 로고
    • Bioreductive drugs into the next millennium
    • Stratford IJ, Workman P. Bioreductive drugs into the next millennium. Anticancer Drug Des 1998;13:519-28.
    • (1998) Anticancer Drug des , vol.13 , pp. 519-528
    • Stratford, I.J.1    Workman, P.2
  • 74
    • 0035415493 scopus 로고    scopus 로고
    • Prodrug strategies in cancer therapy
    • Denny WA. Prodrug strategies in cancer therapy. Eur J Med Chem 2001;36(7-8):577-95.
    • (2001) Eur J Med Chem , vol.36 , Issue.7-8 , pp. 577-595
    • Denny, W.A.1
  • 75
    • 34250326197 scopus 로고    scopus 로고
    • Pretreatment 18F-FAZA PET predicts success of hypoxia-directed radiochemotherapy using tirapazamine
    • Beck R, Roper B, Carlsen JM, Huisman MC, Lebschi JA, Andratschke N et al. Pretreatment 18F-FAZA PET predicts success of hypoxia-directed radiochemotherapy using tirapazamine. J Nucl Med 2007;48:973-80.
    • (2007) J Nucl Med , vol.48 , pp. 973-980
    • Beck, R.1    Roper, B.2    Carlsen, J.M.3    Huisman, M.C.4    Lebschi, J.A.5    Andratschke, N.6
  • 76
    • 77954600498 scopus 로고    scopus 로고
    • Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck TROG 02.02, HeadSTARD: A phase III trial of the Trans-Tasman Radiation Oncology Group
    • Rischin D, Peters LJ, O'Sullivan B, Giralt J, Fisher R, Yuen K et al. Tirapazamine, cisplatin, and radiation versus cisplatin and radiation for advanced squamous cell carcinoma of the head and neck (TROG 02.02, HeadSTARD: a phase III trial of the Trans-Tasman Radiation Oncology Group. J Clin Oncol 2010;28:2989-95.
    • (2010) J Clin Oncol , vol.28 , pp. 2989-2995
    • Rischin, D.1    Peters, L.J.2    O'Sullivan, B.3    Giralt, J.4    Fisher, R.5    Yuen, K.6
  • 77
    • 0344629821 scopus 로고    scopus 로고
    • NLCQ-1 (NSC 709257): Exploiting hypoxia with a weak DNA-intercalating bioreductive drug
    • Papadopoulou MV, Bloomer WD. NLCQ-1 (NSC 709257): exploiting hypoxia with a weak DNA-intercalating bioreductive drug. Clin Cancer Res 2003;9:5714-20.
    • (2003) Clin Cancer Res , vol.9 , pp. 5714-5720
    • Papadopoulou, M.V.1    Bloomer, W.D.2
  • 79
    • 0034213897 scopus 로고    scopus 로고
    • Towards multidimensional radiotherapy MD-CRD: Biological imaging and biological conformality
    • Ling CC, Humm J, Larson S, Amols H, Fuks Z, Leibel S et al. Towards multidimensional radiotherapy (MD-CRD: biological imaging and biological conformality. Int J Radiat Oncol Biol Phys 2000;47:551-60.
    • (2000) Int J Radiat Oncol Biol Phys , vol.47 , pp. 551-560
    • Ling, C.C.1    Humm, J.2    Larson, S.3    Amols, H.4    Fuks, Z.5    Leibel, S.6
  • 81
    • 33749344131 scopus 로고    scopus 로고
    • Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer
    • Rajendran JG, Schwartz DL, O'Sullivan J, Peterson LM, Ng P, Scharnhorst J et al. Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer. Clin Cancer Res 2006;12:5435-41.
    • (2006) Clin Cancer Res , vol.12 , pp. 5435-5441
    • Rajendran, J.G.1    Schwartz, D.L.2    O'Sullivan, J.3    Peterson, L.M.4    Ng, P.5    Scharnhorst, J.6
  • 84
    • 54949157918 scopus 로고    scopus 로고
    • Tumor Hypoxia detected by positron emission tomography with (60)Cu-ATSM as a predictor of response and survival in patients undergoing neoadjuvant chemoradiotherapy for rectal carcinoma: A pilot study
    • Dietz DW, Dehdashti F, Grigsby PW, Malyapa RS, Myerson RJ, Picus J et al. Tumor Hypoxia detected by positron emission tomography with (60)Cu-ATSM as a predictor of response and survival in patients undergoing neoadjuvant chemoradiotherapy for rectal carcinoma: a pilot study. Dis Colon Rectum 2008;51:1641-8
    • (2008) Dis Colon Rectum , vol.51 , pp. 1641-1648
    • Dietz, D.W.1    Dehdashti, F.2    Grigsby, P.W.3    Malyapa, R.S.4    Myerson, R.J.5    Picus, J.6
  • 85
    • 38949098088 scopus 로고    scopus 로고
    • Assessing tumor hypoxia in cervical cancer by PET with 60Cu-labeled diacetyl-bis(N4-methylthiosemicarbazone)
    • Dehdashti F, Grigsby PW, Lewis JS, Laforest R, Siegel BA, Welch MJ. Assessing tumor hypoxia in cervical cancer by PET with 60Cu-labeled diacetyl-bis(N4-methylthiosemicarbazone). J Nucl Med 2008;49:201-5.
    • (2008) J Nucl Med , vol.49 , pp. 201-205
    • Dehdashti, F.1    Grigsby, P.W.2    Lewis, J.S.3    Laforest, R.4    Siegel, B.A.5    Welch, M.J.6
  • 87
    • 39749194493 scopus 로고    scopus 로고
    • The Influence of Changes in Tumor Hypoxia on Dose-Painting Treatment Plans Based on (18)F-FMISO Positron Emission Tomography
    • Lin Z, Mechalakos J, Nehmeh S, Schoder H, Lee N, Humm J et al. The Influence of Changes in Tumor Hypoxia on Dose-Painting Treatment Plans Based on (18)F-FMISO Positron Emission Tomography. Int J Radiat Oncol Biol Phys 2008;70:1219-28.
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , pp. 1219-1228
    • Lin, Z.1    Mechalakos, J.2    Nehmeh, S.3    Schoder, H.4    Lee, N.5    Humm, J.6
  • 89
    • 66149106936 scopus 로고    scopus 로고
    • Prospective Trial Incorporating PreVMid-Treatment t(18)F-Misonidazole Positron Emission Tomography for Head-and-Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy
    • Lee N, Nehmeh S, Schoder H, Fury M, Chan K, Ling CC et al. Prospective Trial Incorporating PreVMid-Treatment t(18)F]-Misonidazole Positron Emission Tomography for Head-and-Neck Cancer Patients Undergoing Concurrent Chemoradiotherapy. Int J Radiat Oncol Biol Phys 2009.
    • (2009) Int J Radiat Oncol Biol Phys
    • Lee, N.1    Nehmeh, S.2    Schoder, H.3    Fury, M.4    Chan, K.5    Ling, C.C.6
  • 90
    • 34250334707 scopus 로고    scopus 로고
    • Hypoxia-imaging with (18)F-Misonidazole and PET: Changes of kinetics during radiotherapy of head-and-neck cancer
    • Eschmann SM, Paulsen F, Bedeshem C, Machulla HJ, Hehr T, Bamberg M et al. Hypoxia-imaging with (18)F-Misonidazole and PET: changes of kinetics during radiotherapy of head-and-neck cancer. Radiother Oncol 2007;83:406-10.
    • (2007) Radiother Oncol , vol.83 , pp. 406-410
    • Eschmann, S.M.1    Paulsen, F.2    Bedeshem, C.3    Machulla, H.J.4    Hehr, T.5    Bamberg, M.6
  • 91
    • 34247871556 scopus 로고    scopus 로고
    • A model of reoxygenation dynamics of head-and-neck tumors based on serial 18F-fluoromisonidazole positron emission tomography investigations
    • Thorwarth D, Eschmann SM, Paulsen F, Alber M. A model of reoxygenation dynamics of head-and-neck tumors based on serial 18F-fluoromisonidazole positron emission tomography investigations. Int J Radiat Oncol Biol Phys 2007;68:515-21.
    • (2007) Int J Radiat Oncol Biol Phys , vol.68 , pp. 515-521
    • Thorwarth, D.1    Eschmann, S.M.2    Paulsen, F.3    Alber, M.4
  • 92
    • 37048999558 scopus 로고    scopus 로고
    • Fluorine-18-Labeled Fluoromisonidazole Positron Emission and Computed Tomography-Guided Intensity-Modulated Radiotherapy for Head and Neck Cancer: A Feasibility Study
    • Lee NY, Mechalakos JG, Nehmeh S, Lin Z, Squire OD, Cai S et al. Fluorine-18-Labeled Fluoromisonidazole Positron Emission and Computed Tomography-Guided Intensity-Modulated Radiotherapy for Head and Neck Cancer: A Feasibility Study. Int J Radiat Oncol Biol Phys 2007;70:2-13.
    • (2007) Int J Radiat Oncol Biol Phys , vol.70 , pp. 2-13
    • Lee, N.Y.1    Mechalakos, J.G.2    Nehmeh, S.3    Lin, Z.4    Squire, O.D.5    Cai, S.6
  • 93
    • 34548511596 scopus 로고    scopus 로고
    • Hypoxia Imaging with FAZA-PET and Theoretical Considerations with Regard to Dose Painting for Individualization of Radiotherapy in Patients with Head and Neck Cancer
    • Grosu AL, Souvatzoglou M, Roper B, Dobritz M, Wiedenmann N, Jacob V et al. Hypoxia Imaging With FAZA-PET and Theoretical Considerations With Regard to Dose Painting for Individualization of Radiotherapy in Patients With Head and Neck Cancer. Int J Radiat Oncol Biol Phys 2007;69:541-51.
    • (2007) Int J Radiat Oncol Biol Phys , vol.69 , pp. 541-551
    • Grosu, A.L.1    Souvatzoglou, M.2    Roper, B.3    Dobritz, M.4    Wiedenmann, N.5    Jacob, V.6
  • 94
    • 67650075036 scopus 로고    scopus 로고
    • Dose painting in radiotherapy for head and neck squamous cell carcinoma: Value of repeated functional imaging with (18)F-FDG PET, (18)F- fluoromisonidazole PET, diffusion-weighted MRI, and dynamic contrast-enhanced MRI
    • Dirix P, Vandecaveye V, De Keyzer F, Stroobants S, Hermans R, Nuyts S. Dose painting in radiotherapy for head and neck squamous cell carcinoma: value of repeated functional imaging with (18)F-FDG PET, (18)F-fluoromisonidazole PET, diffusion-weighted MRI, and dynamic contrast-enhanced MRI. J Nucl Med 2009;50:1020-7.
    • (2009) J Nucl Med , vol.50 , pp. 1020-1027
    • Dirix, P.1    Vandecaveye, V.2    De Keyzer, F.3    Stroobants, S.4    Hermans, R.5    Nuyts, S.6
  • 95
    • 77956185768 scopus 로고    scopus 로고
    • Implementation of hypoxia imaging into treatment planning and delivery
    • Epub ahead of print
    • Thorwarth D, Alber M. Implementation of hypoxia imaging into treatment planning and delivery. Radiother Oncol 2010 [Epub ahead of print].
    • (2010) Radiother Oncol
    • Thorwarth, D.1    Alber, M.2
  • 98
    • 0038172576 scopus 로고    scopus 로고
    • Cancer: Out of air is not out of action
    • Bottaro DP, Liotta LA. Cancer: Out of air is not out of action. Nature 2003;423:593-5.
    • (2003) Nature , vol.423 , pp. 593-595
    • Bottaro, D.P.1    Liotta, L.A.2
  • 99
    • 33947713604 scopus 로고    scopus 로고
    • Optimization of tumour control probability in hypoxic tumours by radiation dose redistribution: A modelling study
    • Sovik A, Malinen E, Bruland OS, Bentzen SM, Olsen DR. Optimization of tumour control probability in hypoxic tumours by radiation dose redistribution: a modelling study. Phys Med Biol 2007;52:499-513.
    • (2007) Phys Med Biol , vol.52 , pp. 499-513
    • Sovik, A.1    Malinen, E.2    Bruland, O.S.3    Bentzen, S.M.4    Olsen, D.R.5
  • 100
    • 63649087353 scopus 로고    scopus 로고
    • Intra-voxel heterogeneity influences the dose prescription for dose-painting with radiotherapy: A modelling study
    • Petit SF, Dekker AL, Seigneuric R, Murrer L, van Riel NA, Nordsmark M et al. Intra-voxel heterogeneity influences the dose prescription for dose-painting with radiotherapy: a modelling study. Phys Med Biol 2009;54:2179-96.
    • (2009) Phys Med Biol , vol.54 , pp. 2179-2196
    • Petit, S.F.1    Dekker, A.L.2    Seigneuric, R.3    Murrer, L.4    Van Riel, N.A.5    Nordsmark, M.6


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