Direct measurements of tumor-tissue pO2. A way of selecting patients for hyperoxic treatment

Strahlentherapie und Onkologie

Volumn 172, Issue SUPPL. 2, 1996, Pages 8-9

  Nordsmark, Marianne ^a  

^a DANISH CANCER SOCIETY RESEARCH CENTER   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER; CONFERENCE PAPER; HUMAN; HYPERBARIC OXYGEN; HYPOXIA; OXYGEN TENSION;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL HYPOXIA; DATA INTERPRETATION, STATISTICAL; FEMALE; FOLLOW-UP STUDIES; HEAD AND NECK NEOPLASMS; HUMANS; HYPERBARIC OXYGENATION; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C3H; NEOPLASMS; OXYGEN; PATIENT SELECTION; POLAROGRAPHY; TIME FACTORS;

EID: 0029844596     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (24)

1. Thomlinson RH, Gray LH The histological structure of some human lung cancers and the possible implications for radiotherapy. Br J Cancer 1955; 9: 539-549.
2. Overgaard J Sensitization of hypoxic tumor cells - clinical experience. Int J Radiat Biol 1989; 56: 801-811.
3. Gray LH, Conger AD, Ebert M et al. The concentration of oxygen dissolved in tissues at the time of irradiation as a factor in radiotherapy Br J Radiol 1953; 26: 638-648.
4. Hewitt HB, and Sakamoto K. The comparative survival of clonogenic cells of murine epithelioma after irradiation in mice breathing air, oxygen and carbon dioxide, or hyperbaric oxygen. Brit J Radiol 1971;44:457-463.
5. Grau C, Horsman MR, Overgaard J. Improving radiation response in a C3H mouse mammary carcinoma during normobaric oxygen and carbogen breathing. Int J Radiat Oncol Biol Phys 1992;22:415-419.
6. Overgaard J, Horsman MR. Modification of hypoxia-induced radioresistance in tumors by the use of oxygen and sensitizers Sem Rad Oncol 1996;6:10-21
7. Rubin P, Hanley J, Keys HM, Marcial V, Brady L. Carbogen breathing during radiation therapy The radiation therapy oncology group study Int J Radiat Oncol Biol Phys 1979;5:1963-1970
8. Rojas A. ARCON: accelerated radiotherapy with carbogen and nicotinamide. In Radiation Science of Molecules, Mice and Men Eds. J. Denekamp & DG Hirst Brit J Radiol. (suppl) 1992;241:174-178
9. Kolstad P Vascularisation, oxygen tension, and radiocurability in cancer of the Cervix. Norwegian Monographs on Medical Science, Oslo Scandinavian University Books, 1968.
10. 2-Histography Int J Radiat Oncol Biol Phys 1990;19: 953-961
11. 2 tension measurements. Cancer Res 1991;51: 3316-3322.
12. 2 tension measurements. Cancer Res 1991;51 6098-6102
13. Lartigau E, Le Ridant AM, Lambin P, Weeger P, Martin L, Sigal R, Lusinchi A, Luboinski B, Eschwege F, Guichard M. Oxygenation of head and neck tumors. Cancer 1993;71: 2319-25.
14. 2 histography Br J Cancer 1992;66: 919-924
15. Nordsmark M, Bentzen SM, Overgaard J. Measurement of human tumor oxygenation status by polarographic needle electrode. An analysis of inter- and intratumor heterogeneity. Acta Oncol 1994;33:383-389
16. Bjergsö P and Kolstad P. Clinical trial with atmospheric oxygen breathing during radiotherapy of cancer of the cervix. Scand J Clin Lab 1968;106:167-171.
17. Pappova N, Siracka E, Vacek A, Durkovsky J., Neoplasm 1982;29:669-674.
18. Martin L, Lartigau E, Weeger P, Lambin P, Le Ridant AM, Lusinchi A, Wibault P, Eschwege F, Luboinsky B, Guichard M. Changes in the oxygenation of head and neck tumors during carbogen breathing Radiother Oncol 1993;27:123-130.
19. Nordsmark M, Grau C, Horsman MR, Jörgensen HS, Overgaard J. Relationship between tumor oxygenation, bioenergetic status and radiobiological hypoxia in an experimental model Acta Oncol 1995;34 329-334.
20. Hoeckel M, Schlenger K, Mitze M, Schäffer U, Vaupel P Hypoxia and radiation response in human tumors. Sem Rad Oncol 1996;6 3-9
21. Gatenby RA, Kessler HB, Rosenblum JS, Coia LR, Moldofsky PJ, Hartz WH, Broder GJ. Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiation therapy. Int J Radiat Oncol Biol Phys 1988; 14: 831-838.
22. Nordsmark M, Overgaard M, Overgaard J. Pretreatment oxygenation predicts radiation response in advanced squamous cell carcinoma of the head and neck Radiother Oncol 1996. In press.
23. Brizel DM, Rosner GL, Prosnitz LR, Dewhirst MW. Tumor oxygenation predicts for likelihood of distant metastases in human soft tissue sarcoma. Cancer Res 1996;56:941-943
24. Beck-Bornholdt, HP and Dubben HH., Potential pitfalls in the use of p-values and in interpretation of significance levels. Radiother Oncol 1994;33:171-176.