Tissue-specific dysregulation of hexose-6-phosphate dehydrogenase and glucose-6-phosphate transporter production in db/db mice as a model of type 2 diabetes

Diabetologia

Volumn 54, Issue 2, 2011, Pages 440-450

  Wang, Y ^a   Nakagawa, Y ^b   Liu, L ^c   Wang, W ^a   Ren, X ^a   Anghel, A ^a   Lutfy, K ^a   Friedman, T C ^a   Liu, Y ^a  

^a CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

11 HSD1; G6PT; G6PT inhibitor; H6PDH; H6PDH siRNA; Insulin resistance; NADPH; Type 2 diabetes

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; CARRIER PROTEIN; CORTICOSTERONE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUCOSE 6 PHOSPHATE TRANSPORTER; MIFEPRISTONE; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTEROID METABOLISM; CORTICOSTERONE BLOOD LEVEL; ENZYME ACTIVITY; G6PT GENE; GENE; GENE EXPRESSION; H6PD GENE; HYPERGLYCEMIA; INSULIN RESISTANCE; LIVER; LIVER CELL; MALE; METABOLIC SYNDROME X; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; UPREGULATION;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ANIMALS; BLOTTING, WESTERN; CARBOHYDRATE DEHYDROGENASES; CELLS, CULTURED; DIABETES MELLITUS, TYPE 2; HEPATOCYTES; MALE; MICE; MICE, INBRED STRAINS; MONOSACCHARIDE TRANSPORT PROTEINS; POLYMERASE CHAIN REACTION;

EID: 78951483893     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-010-1956-9     Document Type: Article

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