Expression of Concern: The Dual Roles of c-Jun NH2-Terminal Kinase Signaling in Cr(VI)-Induced Apoptosis in JB6 Cells (Toxicological Sciences (2011) 119: 2 (335-345) DOI: 10.1093/toxsci/kfq335);The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells

Toxicological Sciences

Volumn 119, Issue 2, 2011, Pages 335-345

  Son, Young Ok ^a   Hitron, John Andrew ^a   Cheng, Senping ^a   Budhraja, Amit ^a   Zhang, Zhuo ^a   Guo, Nancy Lan ^b   Lee, Jeong Chae ^c   Shi, Xianglin ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b WEST VIRGINIA UNIVERSITY   (United States)

^c Chonbuk National University   (South Korea)

Author keywords

Apoptosis; c Jun; Cr(VI); JNK; ROS

Indexed keywords

CASPASE; CHROMIUM; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN; CELL STRAIN JB6; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; EPIDERMIS CELL; GENETIC TRANSFECTION; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION;

EID: 78751682020     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfaa012     Document Type: Erratum

References (55)

1. Bagchi, D., Bagchi, M., and Stohs, S. J. (2001). Chromium (VI)-induced oxidative stress, apoptotic cell death and modulation of p53 tumor suppressor gene. Mol. Cell. Biochem. 222, 149-158.
2. Chang, L., and Karin, M. (2001). Mammalian MAP kinase signalling cascades. Nature 410, 37-40.
3. Chen, L., Ovesen, J. L., Puga, A., and Xia, Y. (2009). Distinct contributions of JNK and p38 to chromium cytotoxicity and inhibition of murine embryonic stem cell differentiation. Environ. Health Perspect. 117, 1124-1130.
4. Chuang, S. M., Liou, G. Y., and Yang, J. L. (2000). Activation of JNK, p38 and ERK mitogen-activated protein kinases by chromium(VI) is mediated through oxidative stress but does not affect cytotoxicity. Carcinogenesis 21, 1491-1500.
5. Clerk, A., Fuller, S. J., Michael, A., and Sugden, P. H. (1998). Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stresses. J. Biol. Chem. 273, 7228-7234.
6. Cohen, M. D., Kargacin, B., Klein, C. B., and Costa, M. (1993). Mechanisms of chromium carcinogenicity and toxicity. Crit. Rev. Toxicol. 23, 255-281.
7. Cossarizza, A., Baccarani-Contri, M., Kalashnikova, G., and Franceschi, C. (1993). A new method for the cytofluorimetric analysis of mitochondrial membrane potential using the J-aggregate forming lipophilic cation 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolcarbocyanine iodide (JC-1). Bio-chem. Biophys. Res. Commun. 197, 40-45.
8. Costa, M. (1997). Toxicity and carcinogenicity of Cr(VI) in animal models and humans. Crit. Rev. Toxicol. 27, 431-442.
9. Davis, R. J. (1995). Transcriptional regulation by MAP kinases. Mol. Reprod. Dev. 42, 459-467.
10. Derijard, B., Hibi, M., Wu, I. H., Barrett, T., Su, B., Deng, T., Karin, M., and Davis, R. J. (1994). JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76, 1025-1037.
11. Ding, M., and Shi, X. (2002). Molecular mechanisms of Cr(VI)-induced carcinogenesis. Mol. Cell. Biochem. 234-235, 293-300.
12. Ding, M., Shi, X., Dong, Z., Chen, F., Lu, Y., Castranova, V., and Vallyathan, V. (1999). Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK. J. Biol. Chem. 274, 30611-30616.
13. Eferl, R., Sibilia, M., Hilberg, F., Fuchsbichler, A., Kufferath, I., Guertl, B., Zenz, R., Wagner, E. F., and Zatloukal, K. (1999). Functions of c-Jun in liver and heart development. J. Cell Biol. 145, 1049-1061.
14. Ge, X., Liu, Z., Qi, W., Shi, X., and Zhai, Q. (2008). Chromium (VI) induces insulin resistance in 3T3-L1 adipocytes through elevated reactive oxygen species generation. Free Radic. Res. 42, 554-563.
15. Gross, A., McDonnell, J. M., and Korsmeyer, S. J. (1999). BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13, 1899-1911.
16. Hansen, M. B., Menne, T., and Johansen, J. D. (2006). Cr(III) and Cr(VI) in leather and elicitation of eczema. Contact Dermatitis 54, 278-282.
17. Harris, M. H., and Thompson, C. B. (2000). The role of the Bcl-2 family in the regulation of outer mitochondrial membrane permeability. Cell Death Differ. 7, 1182-1191.
18. Hilberg, F., Aguzzi, A., Howells, N., and Wagner, E. F. (1993). c-Jun is essential for normal mouse development and hepatogenesis. Nature 365, 179-181.
19. Hodges,N.J.,Adam,B.,Lee,A.J.,Cross,H.J.,andChipman,J.K. (2001). Induction of DNA-strand breaks in human peripheral blood lymphocytes and A549 lung cells by sodium dichromate: association with 8-oxo-2-deoxyguanosine formation and inter-individual variability. Mutagenesis 16, 467-474.
20. Johnson, R. S., van Lingen, B., Papaioannou, V. E., and Spiegelman, B. M. (1993). A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev. 7, 1309-1317.
21. Joseph, P., He, Q., and Umbright, C. (2008). Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts. Toxicol. Sci. 103, 325-334.
22. Kim, G., and Yurkow, E. J. (1996). Chromium induces a persistent activation of mitogen-activated protein kinases by a redox-sensitive mechanism in H4 rat hepatoma cells. Cancer Res. 56, 2045-2051.
23. Kyriakis, J. M., Banerjee, P.N.ikolakakiE., Dai, T., Rubie, E. A., Ahmad, M. F., Avruch, J., and Woodgett, J. R. (1994). The stress-activated protein kinase subfamily of c-Jun kinases. Nature 369, 156-160.
24. Leppa, S., and Bohmann, D. (1999). Diverse functions of JNK signaling and c-Jun in stress response and apoptosis. Oncogene 18, 6158-6162.
25. Li, J. J., Westergaard, C., Ghosh, P., and Colburn, N. H. (1997). Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response. Cancer Res. 57, 3569-3576.
26. Liu, S. L., Lin, X., Shi, D. Y., Cheng, J., Wu, C. Q., and Zhang, Y. D. (2002). Reactive oxygen species stimulated human hepatoma cell proliferation via cross-talk between PI3-K/PKB and JNK signaling pathways. Arch. Biochem. Biophys. 406, 173-182.
27. Munoz, C., Pascual-Salcedo, D., Castellanos, M. C., Alfranca, A., Aragones, J., Vara, A., Redondo, J. M., and de Landazuri, M. O. (1996). Pyrrolidine dithiocarbamate inhibits the production of interleukin-6, interleukin-8, and granulocyte-macrophage colony-stimulating factor by human endothelial cells in response to inflammatory mediators: modulation of NF-kappa B and AP-1 transcription factors activity. Blood 88, 3482-3490.
28. Nechushtan, A., Smith, C. L., Lamensdorf, I., Yoon, S. H., and Youle, R. J. (2001). Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis. J. Cell Biol. 153, 1265-1276.
29. OSHA. (2006). Occupational exposure to hexavalent chromium. Final rule. Fed. Regist. 71, 10099-10385.
30. Pritchard, D. E., Ceryak, S., Ha, L., Fornsaglio, J. L., Hartman, S. K., O'Brien, T. J., and Patierno, S. R. (2001). Mechanism of apoptosis and determination of cellular fate in chromium(VI)-exposed populations of telomerase-immortalized human fibroblasts. Cell Growth Differ. 12, 487-496.
31. Qian, Y., Luo, J., Leonard, S. S., Harris, G. K., Millecchia, L., Flynn, D. C., and Shi, X. (2003). Hydrogen peroxide formation and actin filament reorganization by Cdc42 are essential for ethanol-induced in vitro angiogenesis. J. Biol. Chem. 278, 16189-16197.
32. Samet, J. M., Graves, L. M., Quay, J., Dailey, L. A., Devlin, R. B., Ghio, A. J., Wu, W., Bromberg, P. A., and Reed, W. (1998). Activation of MAPKs in human bronchial epithelial cells exposed to metals. Am. J. Physiol. 275, L551-L558.
33. Schreiber, M., Kolbus, A., Piu, F., Szabowski, A., Mohle-Steinlein, U., Tian, J., Karin, M., Angel, P., and Wagner, E. F. (1999). Control of cell cycle progression by c-Jun is p53 dependent. Genes Dev. 13, 607-619.
34. Shelnutt, S. R., Goad, P., and Belsito, D. V. (2007). Dermatological toxicity of hexavalent chromium. Crit. Rev. Toxicol. 37, 375-387.
35. Shen, H. M., and Liu, Z. G. (2006). JNK signaling pathway is a key modulator in cell death mediated by reactive oxygen and nitrogen species. Free Radic. Biol. Med. 40, 928-939.
36. Shi, X., Chiu, A., Chen, C. T., Halliwell, B., Castranova, V., and Vallyathan, V. (1999). Reduction of chromium(VI) and its relationship to carcinogenesis. J. Toxicol. Environ. Health B Crit. Rev. 2, 87-104.
37. Shi, X. G., and Dalal, N. S. (1990a). On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated chromium(V) species. Arch. Biochem. Biophys. 277, 342-350.
38. Shi, X. L., and Dalal, N. S. (1988). On the mechanism of the chromate reduction by glutathione: ESR evidence for the glutathionyl radical and an isolable Cr(V) intermediate. Biochem. Biophys. Res. Commun. 156, 137-142.
39. Shi, X. L., and Dalal, N. S. (1989). Chromium (V) and hydroxyl radical formation during the glutathione reductase-catalyzed reduction of chromium (VI). Biochem. Biophys. Res. Commun. 163, 627-634.
40. Shi, X. L., and Dalal, N. S. (1990b). ESR spin trapping detection of hydroxyl radicals in the reactions of Cr(V) complexes with hydrogen peroxide. Free Radic. Res. Commun. 10, 17-26.
41. Shi, X. L., and Dalal, N. S. (1990c). Evidence for a Fenton-type mechanism for the generation of dOH radicals in the reduction of Cr(VI) in cellular media. Arch. Biochem. Biophys. 281, 90-95.
42. Shi, X. L., and Dalal, N. S. (1990d). NADPH-dependent flavoenzymes catalyze one electron reduction of metal ions and molecular oxygen and generate hydroxyl radicals. FEBS Lett. 276, 189-191.
43. Singh, J., Carlisle, D. L., Pritchard, D. E., and Patierno, S. R. (1998). Chromium-induced genotoxicity and apoptosis: relationship to chromium carcinogenesis (review). Oncol. Rep. 5, 1307-1318.
44. Son, Y. O., Hitron, J. A., Wang, X., Chang, Q., Pan, J., Zhang, Z., Liu, J., Wang, S., Lee, J. C., and Shi, X. (2010a). Cr(VI) induces mitochondrial-mediated and caspase-dependent apoptosis through reactive oxygen speciesmediated p53 activation in JB6 Cl41 cells. Toxicol. Appl. Pharmacol. 245, 226-235.
45. Son, Y. O., Jang, Y. S., Shi, X., and Lee, J. C. (2009). Activation of JNK and c-Jun is involved in glucose oxidase-mediated cell death of human lymphoma cells. Mol. Cells 28, 545-551.
46. Son, Y. O., Lee, J. C., Hitron, J. A., Pan, J., Zhang, Z., and Shi, X. (2010b). Cadmium induces intracellular Ca2+-and H2O2-dependent apoptosis through JNK-and p53-mediated pathways in skin epidermal cell line. Toxicol. Sci. 113, 127-137.
47. Stohs, S. J., Bagchi, D., Hassoun, E., and Bagchi, M. (2000). Oxidative mechanisms in the toxicity of chromium and cadmium ions. J. Environ. Pathol. Toxicol. Oncol. 19, 201-213.
48. Tobiume, K., Matsuzawa, A., Takahashi, T., Nishitoh, H., Morita, K., Takeda, K., Minowa, O., Miyazono, K., Noda, T., and Ichijo, H. (2001). ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep. 2, 222-228.
49. Ventura, J. J., Kennedy, N. J., Lamb, J. A., Flavell, R. A., and Davis, R. J. (2003). c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor. Mol. Cell. Biol. 23, 2871-2882.
50. Wang, S., Leonard, S. S., Ye, J., Ding, M., and Shi, X. (2000). The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation. Am. J. Physiol. Cell Physiol. 279, C868-C875.
51. Wang, X., Martindale, J. L., Liu, Y., and Holbrook, N. J. (1998).Thecellular response to oxidative stress: influences of mitogen-activated protein kinase signalling pathways on cell survival. Biochem. J. 333(Pt 2), 291-300.
52. Wisdom, R., Johnson, R. S., and Moore, C. (1999). c-Jun regulates cell cycle progression and apoptosis by distinct mechanisms. EMBO J. 18, 188-197.
53. Xu, J., Wise, J. P., and Patierno, S. R. (1992). DNA damage induced by carcinogenic lead chromate particles in cultured mammalian cells. Mutat. Res. 280, 129-136.
54. Ye, J., Zhang, X., Young, H. A., Mao, Y., and Shi, X. (1995). Chromium(VI)-induced nuclear factor-kappa B activation in intact cells via free radical reactions. Carcinogenesis 16, 2401-2405.
55. Zamzami, N., Marchetti, P., Castedo, M., Decaudin, D., Macho, A., Hirsch, T., Susin, S. A., Petit, P. X., Mignotte, B., and Kroemer, G. (1995). Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J. Exp. Med. 182, 367-377.