Distinct contributions of JNK and p38 to chromium cytotoxicity and inhibition of murine embryonic stem cell differentiation

Environmental Health Perspectives

Volumn 117, Issue 7, 2009, Pages 1124-1130

  Chen, Liang ^a   Ovesen, Jerald L ^a   Puga, Alvaro ^a   Xia, Ying ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Chromium; Cytotoxicity; Embryonic stem cell differentiation; ERK; JNK; MAPKs; P38; ROS

Indexed keywords

ACETYLCYSTEINE; ACTIVATING TRANSCRIPTION FACTOR 2; CHROMIUM; DICHROMATE POTASSIUM; GLUTATHIONE; GLUTATHIONE DISULFIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR ELK 1;

ACUTE TOXICITY; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; EMBRYO; EMBRYONIC STEM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HEART MUSCLE CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL; WILD TYPE;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELLS, CULTURED; CHROMIUM; EMBRYONIC STEM CELLS; ENVIRONMENTAL POLLUTANTS; ENZYME ACTIVATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 7; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MURINAE;

EID: 67650891869     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0800157     Document Type: Article

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