-
1
-
-
0037283601
-
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
-
Kahn, SE. (2003) The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes. Diabetologia, 46, pp. 3-19.
-
(2003)
Diabetologia
, vol.46
, pp. 3-19
-
-
Kahn, S.E.1
-
2
-
-
1642377274
-
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
-
Petersen, KF, Dufour, S., Befroy, D., Garcia, R. and Shulman, GI. (2004) Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med, 350, pp. 664-671.
-
(2004)
N Engl J Med
, vol.350
, pp. 664-671
-
-
Petersen, K.F.1
Dufour, S.2
Befroy, D.3
Garcia, R.4
Shulman, G.I.5
-
3
-
-
0026731869
-
Glucose toxicity
-
Yki-Jarvinen, H. (1992) Glucose toxicity. Endocr Rev, 13, pp. 415-431.
-
(1992)
Endocr Rev
, vol.13
, pp. 415-431
-
-
Yki-Jarvinen, H.1
-
4
-
-
34248140740
-
High-fat diet, muscular lipotoxicity and insulin resistance
-
Schrauwen, P. (2007) High-fat diet, muscular lipotoxicity and insulin resistance. Proc Nutr Soc, 66, pp. 33-41.
-
(2007)
Proc Nutr Soc
, vol.66
, pp. 33-41
-
-
Schrauwen, P.1
-
5
-
-
33745861300
-
Inflammation and insulin resistance
-
Shoelson, SE, Lee, J. and Goldfine, AB. (2006) Inflammation and insulin resistance. J Clin Invest, 116, pp. 1793-1801.
-
(2006)
J Clin Invest
, vol.116
, pp. 1793-1801
-
-
Shoelson, S.E.1
Lee, J.2
Goldfine, A.B.3
-
6
-
-
0348222671
-
Inflammation: The link between insulin resistance, obesity and diabetes
-
Dandona, P., Aljada, A. and Bandyopadhyay, A. (2004) Inflammation: The link between insulin resistance, obesity and diabetes. Trends Immunol, 25, pp. 4-7.
-
(2004)
Trends Immunol
, vol.25
, pp. 4-7
-
-
Dandona, P.1
Aljada, A.2
Bandyopadhyay, A.3
-
7
-
-
0036787345
-
Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: An adipokine-mediated process?
-
Gabriely, I., Ma, XH, Yang, XM, Atzmon, G., Rajala, MW, Berg, AH, Scherer, P., Rossetti, L. and Barzilai, N. (2002) Removal of visceral fat prevents insulin resistance and glucose intolerance of aging: An adipokine-mediated process?. Diabetes, 51, pp. 2951-2958.
-
(2002)
Diabetes
, vol.51
, pp. 2951-2958
-
-
Gabriely, I.1
Ma, X.H.2
Yang, X.M.3
Atzmon, G.4
Rajala, M.W.5
Berg, A.H.6
Scherer, P.7
Rossetti, L.8
Barzilai, N.9
-
8
-
-
33751400561
-
Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance
-
Vianna, CR, Huntgeburth, M., Coppari, R., Choi, CS, Lin, J., Krauss, S., Barbatelli, G., Tzameli, I., Kim, YB, Cinti, S., Shulman, GI, Spiegelman, BM and Lowell, BB. (2006) Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance. Cell Metab, 4, pp. 453-464.
-
(2006)
Cell Metab
, vol.4
, pp. 453-464
-
-
Vianna, C.R.1
Huntgeburth, M.2
Coppari, R.3
Choi, C.S.4
Lin, J.5
Krauss, S.6
Barbatelli, G.7
Tzameli, I.8
Kim, Y.B.9
Cinti, S.10
Shulman, G.I.11
Spiegelman, B.M.12
Lowell, B.B.13
-
9
-
-
0038025371
-
Mitochondrial dysfunction in the elderly: Possible role in insulin resistance
-
Petersen, KF, Befroy, D., Dufour, S., Dziura, J., Ariyan, C., Rothman, DL, DiPietro, L., Cline, GW and Shulman, GI. (2003) Mitochondrial dysfunction in the elderly: Possible role in insulin resistance. Science, 300, pp. 1140-1142.
-
(2003)
Science
, vol.300
, pp. 1140-1142
-
-
Petersen, K.F.1
Befroy, D.2
Dufour, S.3
Dziura, J.4
Ariyan, C.5
Rothman, D.L.6
DiPietro, L.7
Cline, G.W.8
Shulman, G.I.9
-
10
-
-
21544471229
-
Oxidative stress, ER stress, and the JNK pathway in type 2 diabetes
-
Kaneto, H., Matsuoka, TA, Nakatani, Y., Kawamori, D., Miyatsuka, T., Matsuhisa, M. and Yamasaki, Y. (2005) Oxidative stress, ER stress, and the JNK pathway in type 2 diabetes. J Mol Med, 83, pp. 429-439.
-
(2005)
J Mol Med
, vol.83
, pp. 429-439
-
-
Kaneto, H.1
Matsuoka, T.A.2
Nakatani, Y.3
Kawamori, D.4
Miyatsuka, T.5
Matsuhisa, M.6
Yamasaki, Y.7
-
11
-
-
34548419344
-
Adipocyte stress: The endoplasmic reticulum and metabolic disease
-
Gregor, MG and Hotamisligil, GS. (2007) Adipocyte stress: The endoplasmic reticulum and metabolic disease. J Lipid Res, 48, pp. 1905-1914.
-
(2007)
J Lipid Res
, vol.48
, pp. 1905-1914
-
-
Gregor, M.G.1
Hotamisligil, G.S.2
-
12
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
Ozcan, U., Yilmaz, E., Ozcan, L., Furuhashi, M., Vaillancourt, E., Smith, RO, Gorgun, CZ and Hotamisligil, GS. (2006) Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science, 313, pp. 1137-1140.
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Gorgun, C.Z.7
Hotamisligil, G.S.8
-
13
-
-
34447331279
-
Soluble RAGE in type 2 diabetes: Association with oxidative stress
-
Devangelio, E., Santilli, F., Formoso, G., Ferroni, P., Bucciarelli, L., Michetti, N., Clissa, C., Ciabattoni, G., Consoli, A. and Davi, G. (2007) Soluble RAGE in type 2 diabetes: Association with oxidative stress. Free Radic Biol Med, 43, pp. 511-518.
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 511-518
-
-
Devangelio, E.1
Santilli, F.2
Formoso, G.3
Ferroni, P.4
Bucciarelli, L.5
Michetti, N.6
Clissa, C.7
Ciabattoni, G.8
Consoli, A.9
Davi, G.10
-
14
-
-
33644768153
-
Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome
-
Fortuno, A., San Jose, G, Moreno, MU, Beloqui, O., Diez, J. and Zalba, G. (2006) Phagocytic NADPH oxidase overactivity underlies oxidative stress in metabolic syndrome. Diabetes, 55, pp. 209-215.
-
(2006)
Diabetes
, vol.55
, pp. 209-215
-
-
Fortuno, A.1
San Jose, G.2
Moreno, M.U.3
Beloqui, O.4
Diez, J.5
Zalba, G.6
-
15
-
-
0141727767
-
N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: Possible role of oxidative stress
-
Haber, CA, Lam, TK, Yu, Z., Gupta, N., Goh, T., Bogdanovic, E., Giacca, A. and Fantus, IG. (2003) N-acetylcysteine and taurine prevent hyperglycemia-induced insulin resistance in vivo: Possible role of oxidative stress. Am J Physiol Endocrinol Metab, 285, pp. E744-E753.
-
(2003)
Am J Physiol Endocrinol Metab
, vol.285
-
-
Haber, C.A.1
Lam, T.K.2
Yu, Z.3
Gupta, N.4
Goh, T.5
Bogdanovic, E.6
Giacca, A.7
Fantus, I.G.8
-
16
-
-
33645860825
-
Reactive oxygen species have a causal role in multiple forms of insulin resistance
-
Houstis, N., Rosen, ED and Lander, ES. (2006) Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature, 440, pp. 944-948.
-
(2006)
Nature
, vol.440
, pp. 944-948
-
-
Houstis, N.1
Rosen, E.D.2
Lander, E.S.3
-
17
-
-
33749070956
-
Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetes-induced oxidative stress
-
Kowluru, RA, Kowluru, V., Xiong, Y. and Ho, YS. (2006) Overexpression of mitochondrial superoxide dismutase in mice protects the retina from diabetes-induced oxidative stress. Free Radic Biol Med, 41, pp. 1191-1196.
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 1191-1196
-
-
Kowluru, R.A.1
Kowluru, V.2
Xiong, Y.3
Ho, Y.S.4
-
18
-
-
0742289404
-
Role of reactive oxygen species and Cr(VI) in Ras-mediated signal transduction
-
Wang, S., Leonard, SS, Ye, J., Gao, N., Wang, L. and Shi, X. (2004) Role of reactive oxygen species and Cr(VI) in Ras-mediated signal transduction. Mol Cell Biochem, 255, pp. 119-127.
-
(2004)
Mol Cell Biochem
, vol.255
, pp. 119-127
-
-
Wang, S.1
Leonard, S.S.2
Ye, J.3
Gao, N.4
Wang, L.5
Shi, X.6
-
19
-
-
34548857700
-
SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
-
Sun, C., Zhang, F., Ge, X., Yan, T., Chen, X., Shi, X. and Zhai, Q. (2007) SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab, 6, pp. 307-319.
-
(2007)
Cell Metab
, vol.6
, pp. 307-319
-
-
Sun, C.1
Zhang, F.2
Ge, X.3
Yan, T.4
Chen, X.5
Shi, X.6
Zhai, Q.7
-
20
-
-
1342304048
-
The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction
-
Mahadev, K., Motoshima, H., Wu, X., Ruddy, JM, Arnold, RS, Cheng, G., Lambeth, JD and Goldstein, BJ. (2004) The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction. Mol Cell Biol, 24, pp. 1844-1854.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1844-1854
-
-
Mahadev, K.1
Motoshima, H.2
Wu, X.3
Ruddy, J.M.4
Arnold, R.S.5
Cheng, G.6
Lambeth, J.D.7
Goldstein, B.J.8
-
21
-
-
0028369668
-
Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells
-
Carter, WO, Narayanan, PK and Robinson, JP. (1994) Intracellular hydrogen peroxide and superoxide anion detection in endothelial cells. J Leukoc Biol, 55, pp. 253-258.
-
(1994)
J Leukoc Biol
, vol.55
, pp. 253-258
-
-
Carter, W.O.1
Narayanan, P.K.2
Robinson, J.P.3
-
22
-
-
0033520938
-
Role of reactive oxygen species and p53 in chromium(VI)-induced apoptosis
-
Ye, J., Wang, S., Leonard, SS, Sun, Y., Butterworth, L., Antonini, J., Ding, M., Rojanasakul, Y., Vallyathan, V., Castranova, V. and Shi, X. (1999) Role of reactive oxygen species and p53 in chromium(VI)-induced apoptosis. J Biol Chem, 274, pp. 34974-34980.
-
(1999)
J Biol Chem
, vol.274
, pp. 34974-34980
-
-
Ye, J.1
Wang, S.2
Leonard, S.S.3
Sun, Y.4
Butterworth, L.5
Antonini, J.6
Ding, M.7
Rojanasakul, Y.8
Vallyathan, V.9
Castranova, V.10
Shi, X.11
-
23
-
-
0033829708
-
The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation
-
Wang, S., Leonard, SS, Ye, J., Ding, M. and Shi, X. (2000) The role of hydroxyl radical as a messenger in Cr(VI)-induced p53 activation. Am J Physiol Cell Physiol, 279, pp. C868-C875.
-
(2000)
Am J Physiol Cell Physiol
, vol.279
-
-
Wang, S.1
Leonard, S.S.2
Ye, J.3
Ding, M.4
Shi, X.5
-
24
-
-
14844327760
-
Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases
-
Kamata, H., Honda, S., Maeda, S., Chang, L., Hirata, H. and Karin, M. (2005) Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell, 120, pp. 649-661.
-
(2005)
Cell
, vol.120
, pp. 649-661
-
-
Kamata, H.1
Honda, S.2
Maeda, S.3
Chang, L.4
Hirata, H.5
Karin, M.6
-
25
-
-
38549085690
-
Involvement of oxidative stress and the JNK pathway in glucose toxicity
-
Kaneto, H., Nakatani, Y., Kawamori, D., Miyatsuka, T. and Matsuoka, TA. (2004) Involvement of oxidative stress and the JNK pathway in glucose toxicity. Rev Diabet Stud, 1, pp. 165-174.
-
(2004)
Rev Diabet Stud
, vol.1
, pp. 165-174
-
-
Kaneto, H.1
Nakatani, Y.2
Kawamori, D.3
Miyatsuka, T.4
Matsuoka, T.A.5
-
26
-
-
0037153158
-
A central role for JNK in obesity and insulin resistance
-
Hirosumi, J., Tuncman, G., Chang, L., Gorgun, CZ, Uysal, KT, Maeda, K., Karin, M. and Hotamisligil, GS. (2002) A central role for JNK in obesity and insulin resistance. Nature, 420, pp. 333-336.
-
(2002)
Nature
, vol.420
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
27
-
-
7044230885
-
Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide
-
Kaneto, H., Nakatani, Y., Miyatsuka, T., Kawamori, D., Matsuoka, TA, Matsuhisa, M., Kajimoto, Y., Ichijo, H., Yamasaki, Y. and Hori, M. (2004) Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide. Nat Med, 10, pp. 1128-1132.
-
(2004)
Nat Med
, vol.10
, pp. 1128-1132
-
-
Kaneto, H.1
Nakatani, Y.2
Miyatsuka, T.3
Kawamori, D.4
Matsuoka, T.A.5
Matsuhisa, M.6
Kajimoto, Y.7
Ichijo, H.8
Yamasaki, Y.9
Hori, M.10
-
28
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
-
Bedard, K. and Krause, KH. (2007) The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology. Physiol Rev, 87, pp. 245-313.
-
(2007)
Physiol Rev
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
29
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M. and Shimomura, I. (2004) Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest, 114, pp. 1752-1761.
-
(2004)
J Clin Invest
, vol.114
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
Nakayama, O.7
Makishima, M.8
Matsuda, M.9
Shimomura, I.10
-
30
-
-
0142053961
-
Inflammation in the prediabetic state is related to increased insulin resistance rather than decreased insulin secretion
-
Festa, A., Hanley, AJ, Tracy, RP, D'Agostino Jr, R. and Haffner, SM. (2003) Inflammation in the prediabetic state is related to increased insulin resistance rather than decreased insulin secretion. Circulation, 108, pp. 1822-1830.
-
(2003)
Circulation
, vol.108
, pp. 1822-1830
-
-
Festa, A.1
Hanley, A.J.2
Tracy, R.P.3
D'Agostino Jr., R.4
Haffner, S.M.5
-
31
-
-
33746270279
-
Increased oxidative stress is associated with decreased circulating levels of adiponectin in Japanese metabolically obese, normal-weight men with normal glucose tolerance
-
Katsuki, A., Suematsu, M., Gabazza, EC, Murashima, S., Nakatani, K., Togashi, K., Yano, Y., Adachi, Y. and Sumida, Y. (2006) Increased oxidative stress is associated with decreased circulating levels of adiponectin in Japanese metabolically obese, normal-weight men with normal glucose tolerance. Diabetes Res Clin Pract, 73, pp. 310-314.
-
(2006)
Diabetes Res Clin Pract
, vol.73
, pp. 310-314
-
-
Katsuki, A.1
Suematsu, M.2
Gabazza, E.C.3
Murashima, S.4
Nakatani, K.5
Togashi, K.6
Yano, Y.7
Adachi, Y.8
Sumida, Y.9
-
32
-
-
33845914986
-
Mechanisms linking obesity with cardiovascular disease
-
Van Gaal, LF, Mertens, IL and De Block, CE. (2006) Mechanisms linking obesity with cardiovascular disease. Nature, 444, pp. 875-880.
-
(2006)
Nature
, vol.444
, pp. 875-880
-
-
Van Gaal, L.F.1
Mertens, I.L.2
De Block, C.E.3
-
33
-
-
34247857663
-
Obesity, inflammation, and insulin resistance
-
Shoelson, SE, Herrero, L. and Naaz, A. (2007) Obesity, inflammation, and insulin resistance. Gastroenterology, 132, pp. 2169-2180.
-
(2007)
Gastroenterology
, vol.132
, pp. 2169-2180
-
-
Shoelson, S.E.1
Herrero, L.2
Naaz, A.3
-
34
-
-
22044443268
-
The molecular basis for oxidative stress-induced insulin resistance
-
Evans, JL, Maddux, BA and Goldfine, ID. (2005) The molecular basis for oxidative stress-induced insulin resistance. Antioxid Redox Signal, 7, pp. 1040-1052.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 1040-1052
-
-
Evans, J.L.1
Maddux, B.A.2
Goldfine, I.D.3
-
35
-
-
33644750396
-
Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes
-
Hotamisligil, GS. (2005) Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes. Diabetes, 54, pp. S73-S78.
-
(2005)
Diabetes
, vol.54
-
-
Hotamisligil, G.S.1
-
36
-
-
17644377918
-
Mismatch repair proteins are activators of toxic responses to chromium-DNA damage
-
Peterson-Roth, E., Reynolds, M., Quievryn, G. and Zhitkovich, A. (2005) Mismatch repair proteins are activators of toxic responses to chromium-DNA damage. Mol Cell Biol, 25, pp. 3596-3607.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3596-3607
-
-
Peterson-Roth, E.1
Reynolds, M.2
Quievryn, G.3
Zhitkovich, A.4
-
37
-
-
0024035192
-
Review of occupational epidemiology of chromium chemicals and respiratory cancer
-
Hayes, RB. (1988) Review of occupational epidemiology of chromium chemicals and respiratory cancer. Sci Total Environ, 71, pp. 331-339.
-
(1988)
Sci Total Environ
, vol.71
, pp. 331-339
-
-
Hayes, R.B.1
-
38
-
-
0025986877
-
Chromium and disease: Review of epidemiologic studies with particular reference to etiologic information provided by measures of exposure
-
Lees, PS. (1991) Chromium and disease: Review of epidemiologic studies with particular reference to etiologic information provided by measures of exposure. Environ Health Perspect, 92, pp. 93-104.
-
(1991)
Environ Health Perspect
, vol.92
, pp. 93-104
-
-
Lees, P.S.1
-
39
-
-
0033374068
-
Reduction of chromium(VI) and its relationship to carcinogenesis
-
Shi, X., Chiu, A., Chen, CT, Halliwell, B., Castranova, V. and Vallyathan, V. (1999) Reduction of chromium(VI) and its relationship to carcinogenesis. J Toxicol Environ Health B Crit Rev, 2, pp. 87-104.
-
(1999)
J Toxicol Environ Health B Crit Rev
, vol.2
, pp. 87-104
-
-
Shi, X.1
Chiu, A.2
Chen, C.T.3
Halliwell, B.4
Castranova, V.5
Vallyathan, V.6
-
40
-
-
0025241038
-
On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated chromium(V) species
-
Shi, XG and Dalal, NS. (1990) On the hydroxyl radical formation in the reaction between hydrogen peroxide and biologically generated chromium(V) species. Arch Biochem Biophys, 277, pp. 342-350.
-
(1990)
Arch Biochem Biophys
, vol.277
, pp. 342-350
-
-
Shi, X.G.1
Dalal, N.S.2
-
41
-
-
0024427134
-
Chromium (V) and hydroxyl radical formation during the glutathione reductase-catalyzed reduction of chromium (VI)
-
Shi, XL and Dalal, NS. (1989) Chromium (V) and hydroxyl radical formation during the glutathione reductase-catalyzed reduction of chromium (VI). Biochem Biophys Res Commun, 163, pp. 627-634.
-
(1989)
Biochem Biophys Res Commun
, vol.163
, pp. 627-634
-
-
Shi, X.L.1
Dalal, N.S.2
-
42
-
-
0030924918
-
Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes
-
Rudich, A., Kozlovsky, N., Potashnik, R. and Bashan, N. (1997) Oxidant stress reduces insulin responsiveness in 3T3-L1 adipocytes. Am J Physiol, 272, pp. E935-E940.
-
(1997)
Am J Physiol
, vol.272
-
-
Rudich, A.1
Kozlovsky, N.2
Potashnik, R.3
Bashan, N.4
-
43
-
-
0032799487
-
Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes
-
Rudich, A., Tirosh, A., Potashnik, R., Khamaisi, M. and Bashan, N. (1999) Lipoic acid protects against oxidative stress induced impairment in insulin stimulation of protein kinase B and glucose transport in 3T3-L1 adipocytes. Diabetologia, 42, pp. 949-957.
-
(1999)
Diabetologia
, vol.42
, pp. 949-957
-
-
Rudich, A.1
Tirosh, A.2
Potashnik, R.3
Khamaisi, M.4
Bashan, N.5
-
44
-
-
0033537830
-
Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes
-
Tirosh, A., Potashnik, R., Bashan, N. and Rudich, A. (1999) Oxidative stress disrupts insulin-induced cellular redistribution of insulin receptor substrate-1 and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. A putative cellular mechanism for impaired protein kinase B activation and GLUT4 translocation. J Biol Chem, 274, pp. 10595-10602.
-
(1999)
J Biol Chem
, vol.274
, pp. 10595-10602
-
-
Tirosh, A.1
Potashnik, R.2
Bashan, N.3
Rudich, A.4
-
45
-
-
0036796875
-
Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
-
Evans, JL, Goldfine, ID, Maddux, BA and Grodsky, GM. (2002) Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes. Endocr Rev, 23, pp. 599-622.
-
(2002)
Endocr Rev
, vol.23
, pp. 599-622
-
-
Evans, J.L.1
Goldfine, I.D.2
Maddux, B.A.3
Grodsky, G.M.4
-
46
-
-
33745324596
-
Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes
-
Natali, A., Toschi, E., Baldeweg, S., Ciociaro, D., Favilla, S., Sacca, L. and Ferrannini, E. (2006) Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes. Diabetes, 55, pp. 1133-1140.
-
(2006)
Diabetes
, vol.55
, pp. 1133-1140
-
-
Natali, A.1
Toschi, E.2
Baldeweg, S.3
Ciociaro, D.4
Favilla, S.5
Sacca, L.6
Ferrannini, E.7
-
47
-
-
20044387026
-
IKK-beta links inflammation to obesity-induced insulin resistance
-
Arkan, MC, Hevener, AL, Greten, FR, Maeda, S., Li, ZW, Long, JM, Wynshaw-Boris, A., Poli, G., Olefsky, J. and Karin, M. (2005) IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med, 11, pp. 191-198.
-
(2005)
Nat Med
, vol.11
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.W.5
Long, J.M.6
Wynshaw-Boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
|