Distinct Nrf1/2-independent mechanisms mediate As3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes

Free Radical Biology and Medicine

Volumn 46, Issue 12, 2009, Pages 1614-1625

  Thompson, James A ^a   White, Collin C ^a   Cox, David P ^a   Chan, Jefferson Y ^b   Kavanagh, Terrance J ^a   Fausto, Nelson ^a   Franklin, Christopher C ^c,d  

^a UNIVERSITY OF WASHINGTON   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

Arsenic; Arsenite; Free radicals; Gene transcription; Glutamate cysteine ligase; Glutathione; Hepatocyte; Nrf2

Indexed keywords

ACETYLCYSTEINE; ARSENIC TRIOXIDE; GLUTAMATE CYSTEINE LIGASE; MITOGEN ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF1; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ARTICLE; GENE EXPRESSION; GENETIC TRANSCRIPTION; LIVER CELL; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ARSENITES; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMATE-CYSTEINE LIGASE; HEPATOCYTES; MICE; MICE, TRANSGENIC; NUCLEAR RESPIRATORY FACTOR 1; RNA, MESSENGER; TRANSCRIPTION, GENETIC; UP-REGULATION;

MURINAE;

EID: 67349186705     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.03.016     Document Type: Article

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