메뉴 건너뛰기




Volumn 19, Issue 11, 2010, Pages 1359-1367

Liposomal formulations of thrombomodulin increase engraftment after intraportal islet transplantation

Author keywords

Engraftment; Inflammation; Islet transplantation; Thrombomodulin; Thrombosis

Indexed keywords

FIBRIN; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MESSENGER RNA; THROMBOMODULIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 78651483943     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368910X513964     Document Type: Article
Times cited : (16)

References (78)
  • 1
    • 0028199745 scopus 로고
    • Effects of recombinant human soluble thrombomodulin (rhs-TM) on a rat model of disseminated intravascular coagulation with decreased levels of plasma antithrombin III
    • Aoki, Y.; Ohishi, R.; Takei, R.; Matsuzaki, O.; Mohri, M.; Saitoh, K.; Gomi, K.; Sugihara, T.; Kiyota, T.; Yamamoto, S. Effects of recombinant human soluble thrombomodulin (rhs-TM) on a rat model of disseminated intravascular coagulation with decreased levels of plasma antithrombin III. Thromb. Haemost. 71(4):452-455; 1994.
    • (1994) Thromb. Haemost. , vol.71 , Issue.4 , pp. 452-455
    • Aoki, Y.1    Ohishi, R.2    Takei, R.3    Matsuzaki, O.4    Mohri, M.5    Saitoh, K.6    Gomi, K.7    Sugihara, T.8    Kiyota, T.9    Yamamoto, S.10
  • 3
  • 4
    • 18244364592 scopus 로고    scopus 로고
    • Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: Implications for intrahepatic grafts
    • Barshes, N. R.; Wyllie, S.; Goss, J. A. Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: Implications for intrahepatic grafts. J. Leukoc. Biol. 77(5):587-597; 2005.
    • (2005) J. Leukoc. Biol. , vol.77 , Issue.5 , pp. 587-597
    • Barshes, N.R.1    Wyllie, S.2    Goss, J.A.3
  • 5
    • 0034576863 scopus 로고    scopus 로고
    • Isolated human islets trigger an instant blood mediated inflammatory reaction: Implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes
    • Bennet, W.; Groth, C. G.; Larsson, R.; Nilsson, B.; Korsgren, O. Isolated human islets trigger an instant blood mediated inflammatory reaction: Implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes. Ups. J. Med. Sci. 105(2):125-133; 2000.
    • (2000) Ups. J. Med. Sci. , vol.105 , Issue.2 , pp. 125-133
    • Bennet, W.1    Groth, C.G.2    Larsson, R.3    Nilsson, B.4    Korsgren, O.5
  • 9
    • 0028090678 scopus 로고
    • Activation of intragraft endothelial and mononuclear cells during discordant xenograft rejection
    • Blakely, M. L.; Van der Werf, W. J.; Berndt, M. C.; Dalmasso, A. P.; Bach, F. H.; Hancock, W. W. Activation of intragraft endothelial and mononuclear cells during discordant xenograft rejection. Transplantation 58(10):1059-1066; 1994.
    • (1994) Transplantation , vol.58 , Issue.10 , pp. 1059-1066
    • Blakely, M.L.1    Van Der Werf, W.J.2    Berndt, M.C.3    Dalmasso, A.P.4    Bach, F.H.5    Hancock, W.W.6
  • 10
    • 0031890972 scopus 로고    scopus 로고
    • Transplantation of allogeneic islets of Langerhans in the rat liver: Effects of macrophage depletion on graft survival and microenvironment activation
    • Bottino, R.; Fernandez, L. A.; Ricordi, C.; Lehmann, R.; Tsan, M. F.; Oliver, R.; Inverardi, L. Transplantation of allogeneic islets of Langerhans in the rat liver: Effects of macrophage depletion on graft survival and microenvironment activation. Diabetes 47(3):316-323; 1998.
    • (1998) Diabetes , vol.47 , Issue.3 , pp. 316-323
    • Bottino, R.1    Fernandez, L.A.2    Ricordi, C.3    Lehmann, R.4    Tsan, M.F.5    Oliver, R.6    Inverardi, L.7
  • 11
    • 0036191244 scopus 로고    scopus 로고
    • Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N
    • Campbell, W. D.; Lazoura, E.; Okada, N.; Okada, H. Inactivation of C3a and C5a octapeptides by carboxypeptidase R and carboxypeptidase N. Microbiol. Immunol. 46(2): 131-134; 2002.
    • (2002) Microbiol. Immunol. , vol.46 , Issue.2 , pp. 131-134
    • Campbell, W.D.1    Lazoura, E.2    Okada, N.3    Okada, H.4
  • 12
    • 0032502978 scopus 로고    scopus 로고
    • Linkage between inflammation and coagulation: An update on the molecular basis of the crosstalk
    • Cicala, C.; Cirino, G. Linkage between inflammation and coagulation: An update on the molecular basis of the crosstalk. Life Sci. 62(20):1817-1824; 1998.
    • (1998) Life Sci , vol.62 , Issue.20 , pp. 1817-1824
    • Cicala, C.1    Cirino, G.2
  • 13
    • 7044229738 scopus 로고    scopus 로고
    • Activated protein C preserves functional islet mass after intraportal transplantation: A novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death
    • Contreras, J. L.; Eckstein, C.; Smyth, C. A.; Bilbao, G.; Vilatoba, M.; Ringland, S. E.; Young, C.; Thompson, J. A.; Fernandez, J. A.; Griffin, J. H.; Eckhoff, D. E. Activated protein C preserves functional islet mass after intraportal transplantation: A novel link between endothelial cell activation, thrombosis, inflammation, and islet cell death. Diabetes 53(11):2804-2814; 2004.
    • (2004) Diabetes , vol.53 , Issue.11 , pp. 2804-2814
    • Contreras, J.L.1    Eckstein, C.2    Smyth, C.A.3    Bilbao, G.4    Vilatoba, M.5    Ringland, S.E.6    Young, C.7    Thompson, J.A.8    Fernandez, J.A.9    Griffin, J.H.10    Eckhoff, D.E.11
  • 14
    • 0036719075 scopus 로고    scopus 로고
    • The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways
    • Conway, E. M.; Van de Wouwer, M.; Pollefeyt, S.; Jurk, K.; Van Aken, H.; De Vriese, A.; Weitz, J. I.; Weiler, H.; Hellings, P. W.; Schaeffer, P.; Herbert, J. M.; Collen, D.; Theilmeier, G. The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways. J. Exp. Med. 196(5):565-577; 2002.
    • (2002) J. Exp. Med. , vol.196 , Issue.5 , pp. 565-577
    • Conway, E.M.1    Van De Wouwer, M.2    Pollefeyt, S.3    Jurk, K.4    Van Aken, H.5    De Vriese, A.6    Weitz, J.I.7    Weiler, H.8    Hellings, P.W.9    Schaeffer, P.10    Herbert, J.M.11    Collen, D.12    Theilmeier, G.13
  • 15
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • Coughlin, S. R. Thrombin signalling and protease-activated receptors. Nature 407:258-264; 2000.
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 17
    • 0028963533 scopus 로고
    • A selective decrease in the beta cell mass of human islets transplanted into diabetic nude mice
    • Davalli, A. M.; Ogawa, Y.; Ricordi, C.; Scharp, D. W.; Bonner-Weir, S.; Weir, G. C. A selective decrease in the beta cell mass of human islets transplanted into diabetic nude mice. Transplantation 59(6):817-820; 1995.
    • (1995) Transplantation , vol.59 , Issue.6 , pp. 817-820
    • Davalli, A.M.1    Ogawa, Y.2    Ricordi, C.3    Scharp, D.W.4    Bonner-Weir, S.5    Weir, G.C.6
  • 18
    • 0029821899 scopus 로고    scopus 로고
    • Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function
    • Davalli, A. M.; Scaglia, L.; Zangen, D. H.; Hollister, J.; Bonner-Weir, S.; Weir, G. C. Vulnerability of islets in the immediate posttransplantation period. Dynamic changes in structure and function. Diabetes 45(9):1161-1167; 1996.
    • (1996) Diabetes , vol.45 , Issue.9 , pp. 1161-1167
    • Davalli, A.M.1    Scaglia, L.2    Zangen, D.H.3    Hollister, J.4    Bonner-Weir, S.5    Weir, G.C.6
  • 19
    • 0036357526 scopus 로고    scopus 로고
    • Receptors of the PAR family as a link between blood coagulation and inflammation
    • Mosc.
    • Dugina, T. N.; Kiseleva, E. V.; Chistov, I. V.; Umarova, B. A.; Strukova, S. M. Receptors of the PAR family as a link between blood coagulation and inflammation. Biochemistry (Mosc.) 67(1):65-74; 2002.
    • (2002) Biochemistry , vol.67 , Issue.1 , pp. 65-74
    • Dugina, T.N.1    Kiseleva, E.V.2    Chistov, I.V.3    Umarova, B.A.4    Strukova, S.M.5
  • 20
    • 0038683379 scopus 로고    scopus 로고
    • Coagulation and inflammation
    • Esmon, C. T. Coagulation and inflammation. J. Endotoxin Res. 9(3):192-198; 2003.
    • (2003) J. Endotoxin Res. , vol.9 , Issue.3 , pp. 192-198
    • Esmon, C.T.1
  • 21
    • 1942439753 scopus 로고    scopus 로고
    • Crosstalk between inflammation and thrombosis
    • Esmon, C. T. Crosstalk between inflammation and thrombosis. Maturitas 47(4):305-314; 2004.
    • (2004) Maturitas , vol.47 , Issue.4 , pp. 305-314
    • Esmon, C.T.1
  • 22
    • 33646480218 scopus 로고    scopus 로고
    • Inflammation and the activated protein C anticoagulant pathway
    • Esmon, C. T. Inflammation and the activated protein C anticoagulant pathway. Semin. Thromb. Hemost. 32(Suppl. 1):49-60; 2006.
    • (2006) Semin. Thromb. Hemost. , vol.32 , Issue.SUPPL. 1 , pp. 49-60
    • Esmon, C.T.1
  • 23
    • 0029023233 scopus 로고
    • Inflammation and thrombosis: The impact of inflammation on the protein C anticoagulant pathway
    • Esmon, C. T. Inflammation and thrombosis: The impact of inflammation on the protein C anticoagulant pathway. Haematologica 80(2 Suppl.):49-56; 1995.
    • (1995) Haematologica , vol.80 , Issue.2 SUPPL. , pp. 49-56
    • Esmon, C.T.1
  • 24
    • 0034912330 scopus 로고    scopus 로고
    • Role of coagulation inhibitors in inflammation
    • Esmon, C. T. Role of coagulation inhibitors in inflammation. Thromb. Haemost. 86(1):51-56; 2001.
    • (2001) Thromb. Haemost. , vol.86 , Issue.1 , pp. 51-56
    • Esmon, C.T.1
  • 25
    • 0033830963 scopus 로고    scopus 로고
    • The anticoagulant and anti-inflammatory roles of the protein C anticoagulant pathway
    • Esmon, C. T. The anticoagulant and anti-inflammatory roles of the protein C anticoagulant pathway. J. Autoimmun. 15(2):113-116; 2000.
    • (2000) J. Autoimmun. , vol.15 , Issue.2 , pp. 113-116
    • Esmon, C.T.1
  • 26
    • 7044262108 scopus 로고    scopus 로고
    • The impact of the inflammatory response on coagulation
    • Esmon, C. T. The impact of the inflammatory response on coagulation. Thromb. Res. 114(5-6):321-327; 2004.
    • (2004) Thromb. Res. , vol.114 , Issue.5-6 , pp. 321-327
    • Esmon, C.T.1
  • 27
    • 33644801469 scopus 로고    scopus 로고
    • The interactions between inflammation and coagulation
    • Esmon, C. T. The interactions between inflammation and coagulation. Br. J. Haematol. 131(4):417-430; 2005.
    • (2005) Br. J. Haematol. , vol.131 , Issue.4 , pp. 417-430
    • Esmon, C.T.1
  • 28
    • 0035222641 scopus 로고    scopus 로고
    • The normal role of activated protein C in maintaining homeostasis and its relevance to critical illness
    • Esmon, C. T. The normal role of activated protein C in maintaining homeostasis and its relevance to critical illness. Crit. Care 5(2):S7-12; 2001.
    • (2001) Crit. Care , vol.5 , Issue.2
    • Esmon, C.T.1
  • 32
    • 8444244831 scopus 로고    scopus 로고
    • Recombinant human activated protein C in the treatment of severe sepsis: An evidence-based review
    • Fourrier, F. Recombinant human activated protein C in the treatment of severe sepsis: An evidence-based review. Crit. Care Med. 32(11 Suppl.):S534-541; 2004.
    • (2004) Crit. Care Med. , vol.32 , Issue.11 SUPPL.
    • Fourrier, F.1
  • 33
    • 0030832761 scopus 로고    scopus 로고
    • Fatal disseminated intravascular coagulation after autologous islet transplantation
    • Froberg, M. K.; Leone, J. P.; Jessurun, J.; Sutherland, D. E. Fatal disseminated intravascular coagulation after autologous islet transplantation. Hum. Pathol. 28:1295-1298; 1997.
    • (1997) Hum. Pathol. , vol.28 , pp. 1295-1298
    • Froberg, M.K.1    Leone, J.P.2    Jessurun, J.3    Sutherland, D.E.4
  • 35
    • 0027291336 scopus 로고
    • Antithrombotic effect of recombinant human soluble thrombomodulin on endotoxin-induced disseminated intravascular coagulation in rats
    • Gonda, Y.; Hirata, S.; Saitoh, K.; Aoki, Y.; Mohri, M.; Gomi, K.; Sugihara, T.; Kiyota, T.; Yamamoto, S.; Ishida, T. Antithrombotic effect of recombinant human soluble thrombomodulin on endotoxin-induced disseminated intravascular coagulation in rats. Thromb. Res. 71(4):325-335; 1993.
    • (1993) Thromb. Res. , vol.71 , Issue.4 , pp. 325-335
    • Gonda, Y.1    Hirata, S.2    Saitoh, K.3    Aoki, Y.4    Mohri, M.5    Gomi, K.6    Sugihara, T.7    Kiyota, T.8    Yamamoto, S.9    Ishida, T.10
  • 36
    • 1442289560 scopus 로고    scopus 로고
    • Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood-mediated inflammatory reaction
    • Goto, M.; Groth, C. G.; Nilsson, B.; Korsgren, O. Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood-mediated inflammatory reaction. Xenotransplantation 11(2):195-202; 2004.
    • (2004) Xenotransplantation , vol.11 , Issue.2 , pp. 195-202
    • Goto, M.1    Groth, C.G.2    Nilsson, B.3    Korsgren, O.4
  • 37
    • 2942687195 scopus 로고    scopus 로고
    • Low-molecular weight dextran sulfate abrogates the instant blood-mediated inflammatory reaction induced by adult porcine islets both in vitro and in vivo
    • Goto, M.; Johansson, H.; Maeda, A.; Elgue, G.; Korsgren, O.; Nilsson, B. Low-molecular weight dextran sulfate abrogates the instant blood-mediated inflammatory reaction induced by adult porcine islets both in vitro and in vivo. Transplant. Proc. 36(4):1186-1187; 2004.
    • (2004) Transplant. Proc. , vol.36 , Issue.4 , pp. 1186-1187
    • Goto, M.1    Johansson, H.2    Maeda, A.3    Elgue, G.4    Korsgren, O.5    Nilsson, B.6
  • 38
    • 0029873131 scopus 로고    scopus 로고
    • A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes
    • Grey, S. T.; Hancock, W. W. A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes. J. Immunol. 156(6):2256-2263; 1996.
    • (1996) J. Immunol. , vol.156 , Issue.6 , pp. 2256-2263
    • Grey, S.T.1    Hancock, W.W.2
  • 39
    • 0027998013 scopus 로고
    • Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN-gamma, or phorbol ester
    • Grey, S. T.; Tsuchida, A.; Hau, H.; Orthner, C. L.; Salem, H. H.; Hancock, W. W. Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN-gamma, or phorbol ester. J. Immunol. 153(8):3664-3672; 1994.
    • (1994) J. Immunol. , vol.153 , Issue.8 , pp. 3664-3672
    • Grey, S.T.1    Tsuchida, A.2    Hau, H.3    Orthner, C.L.4    Salem, H.H.5    Hancock, W.W.6
  • 40
    • 0028299926 scopus 로고
    • Human protein C inhibits selectin-mediated cell adhesion: Role of unique fucosylated oligosaccharide
    • Grinnell, B. W.; Hermann, R. B.; Yan, S. B. Human protein C inhibits selectin-mediated cell adhesion: Role of unique fucosylated oligosaccharide. Glycobiology 4:221-226; 1994.
    • (1994) Glycobiology , vol.4 , pp. 221-226
    • Grinnell, B.W.1    Hermann, R.B.2    Yan, S.B.3
  • 41
    • 0024556368 scopus 로고
    • Inhibition of platelet-dependent thrombus formation by human activated protein C in a primate model
    • Gruber, A.; Griffin, J. H.; Harker, L. A.; Hanson, S. R. Inhibition of platelet-dependent thrombus formation by human activated protein C in a primate model. Blood 73(3):639-642; 1989.
    • (1989) Blood , vol.73 , Issue.3 , pp. 639-642
    • Gruber, A.1    Griffin, J.H.2    Harker, L.A.3    Hanson, S.R.4
  • 42
    • 33645738564 scopus 로고    scopus 로고
    • Reconstitution of CD39 in liposomes amplifies nucleoside triphsphate diphosphohydrolase activity and restores thromboregulatory properties
    • Haller, C. A.; Cui, W.; Wen, J.; Robson, S. C.; Chaikof, E. L. Reconstitution of CD39 in liposomes amplifies nucleoside triphsphate diphosphohydrolase activity and restores thromboregulatory properties. J. Vasc. Surg. 43(4):816-823; 2006.
    • (2006) J. Vasc. Surg. , vol.43 , Issue.4 , pp. 816-823
    • Haller, C.A.1    Cui, W.2    Wen, J.3    Robson, S.C.4    Chaikof, E.L.5
  • 43
    • 0030755533 scopus 로고    scopus 로고
    • Immunobiology and therapeutic applications of protein C/protein S/thrombomodulin in human and experimental allotransplantation and xenotransplantation
    • Hancock, W. W.; Bach, F. H. Immunobiology and therapeutic applications of protein C/protein S/thrombomodulin in human and experimental allotransplantation and xenotransplantation. Trends Cardiovasc. Med. 7:174-183; 1997.
    • (1997) Trends Cardiovasc. Med. , vol.7 , pp. 174-183
    • Hancock, W.W.1    Bach, F.H.2
  • 44
    • 32144450677 scopus 로고    scopus 로고
    • Activated protein C and the ovarian hyperstimulation syndrome: Possible therapeutic implications
    • Hitkari, J. A.; Rowe, T. P.; von Dadelszen, P. Activated protein C and the ovarian hyperstimulation syndrome: Possible therapeutic implications. Med. Hypotheses 66(5):929-933; 2006.
    • (2006) Med. Hypotheses , vol.66 , Issue.5 , pp. 929-933
    • Hitkari, J.A.1    Rowe, T.P.2    Von Dadelszen, P.3
  • 45
    • 0344443722 scopus 로고    scopus 로고
    • Thrombomodulin-mediated cell adhesion: Involvement of its lectin-like domain
    • Huang, H. C.; Shi, G. Y.; Jiang, S. J.; Shi, C. S.; Wu, C. M.; Yang, H. Y.; Wu, H. L. Thrombomodulin-mediated cell adhesion: Involvement of its lectin-like domain. J. Biol. Chem. 278(47):46750-46759; 2003.
    • (2003) J. Biol. Chem. , vol.278 , Issue.47 , pp. 46750-46759
    • Huang, H.C.1    Shi, G.Y.2    Jiang, S.J.3    Shi, C.S.4    Wu, C.M.5    Yang, H.Y.6    Wu, H.L.7
  • 47
    • 0028225856 scopus 로고
    • Effect of 15-deoxyspergualin on immediate function and long-term survival of transplanted islets in murine recipients of a marginal islet mass
    • Kaufman, D. B.; Gores, P. F.; Field, M. J.; Farney, A. C.; Gruber, S. A.; Stephanian, E.; Sutherland, D. E. Effect of 15-deoxyspergualin on immediate function and long-term survival of transplanted islets in murine recipients of a marginal islet mass. Diabetes 43(6):778-783; 1994.
    • (1994) Diabetes , vol.43 , Issue.6 , pp. 778-783
    • Kaufman, D.B.1    Gores, P.F.2    Field, M.J.3    Farney, A.C.4    Gruber, S.A.5    Stephanian, E.6    Sutherland, D.E.7
  • 48
    • 23844438376 scopus 로고    scopus 로고
    • Dose-response study of recombinant human soluble thrombomodulin (ART-123) in the prevention of venous thromboembolism after total hip replacement
    • Kearon, C.; Comp, P.; Douketis, J.; Royds, R.; Yamada, K.; Gent, M. Dose-response study of recombinant human soluble thrombomodulin (ART-123) in the prevention of venous thromboembolism after total hip replacement. J. Thromb. Haemost. 3(5):962-968; 2005.
    • (2005) J. Thromb. Haemost. , vol.3 , Issue.5 , pp. 962-968
    • Kearon, C.1    Comp, P.2    Douketis, J.3    Royds, R.4    Yamada, K.5    Gent, M.6
  • 49
    • 0015804157 scopus 로고
    • Transplantation of isolated pancreatic islets into the portal vein of diabetic rats
    • Kemp, C. B.; Knight, M. J.; Scharp, D. W.; Lacy, P. E.; Ballinger, W. F. Transplantation of isolated pancreatic islets into the portal vein of diabetic rats. Nature 244(5416):447; 1973.
    • (1973) Nature , vol.244 , Issue.5416 , pp. 447
    • Kemp, C.B.1    Knight, M.J.2    Scharp, D.W.3    Lacy, P.E.4    Ballinger, W.F.5
  • 50
    • 0029981458 scopus 로고    scopus 로고
    • Protection of mouse islet isografts from nonspecific inflammatory damage by recipient treatment with nicotinamide and 15-deoxyspergualin
    • Kenmochi, T.; Miyamoto, M.; Mullen, Y. Protection of mouse islet isografts from nonspecific inflammatory damage by recipient treatment with nicotinamide and 15-deoxyspergualin. Cell Transplant. 5(1):41-47; 1996.
    • (1996) Cell Transplant , vol.5 , Issue.1 , pp. 41-47
    • Kenmochi, T.1    Miyamoto, M.2    Mullen, Y.3
  • 51
    • 0023924509 scopus 로고
    • A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice
    • Kumada, T.; Dittman, W. A.; Majerus, P. W. A role for thrombomodulin in the pathogenesis of thrombin-induced thromboembolism in mice. Blood 71(3):728-733; 1988.
    • (1988) Blood , vol.71 , Issue.3 , pp. 728-733
    • Kumada, T.1    Dittman, W.A.2    Majerus, P.W.3
  • 52
    • 40649102666 scopus 로고    scopus 로고
    • Recombinant human activated protein C: Current insights into its mechanism of action
    • Levi, M.; van der Poll, T. Recombinant human activated protein C: Current insights into its mechanism of action. Crit. Care 11(Suppl. 5):S3; 2007.
    • (2007) Crit. Care , vol.11 , Issue.SUPPL. 5
    • Levi, M.1    Van Der Poll, T.2
  • 53
    • 26444440564 scopus 로고    scopus 로고
    • Two-way interactions between inflammation and coagulation
    • Levi, M.; van der Poll, T. Two-way interactions between inflammation and coagulation. Trends Cardiovasc. Med. 15(7):254-259; 2005.
    • (2005) Trends Cardiovasc. Med. , vol.15 , Issue.7 , pp. 254-259
    • Levi, M.1    Van Der Poll, T.2
  • 54
    • 62549132686 scopus 로고    scopus 로고
    • Intrahepatic islet transplant in the mouse: Functional and morphological characterization
    • Melzi, R.; Sanvito, F.; Mercalli, A.; Andralojc, K.; Bonifacio, E.; Piemonti, L. Intrahepatic islet transplant in the mouse: Functional and morphological characterization. Cell Transplant. 17(12):1361-1370; 2008.
    • (2008) Cell Transplant , vol.17 , Issue.12 , pp. 1361-1370
    • Melzi, R.1    Sanvito, F.2    Mercalli, A.3    Andralojc, K.4    Bonifacio, E.5    Piemonti, L.6
  • 56
    • 0028230847 scopus 로고
    • Intravenous extended infusion of recombinant human soluble thrombomodulin prevented tissue factor-induced disseminated intravascular coagulation in rats
    • Mohri, M.; Oka, M.; Aoki, Y.; Gonda, Y.; Hirata, S.; Gomi, K.; Kiyota, T.; Sugihara, T.; Yamamoto, S.; Ishida, T. Intravenous extended infusion of recombinant human soluble thrombomodulin prevented tissue factor-induced disseminated intravascular coagulation in rats. Am. J. Hematol. 45(4):298-303; 1994.
    • (1994) Am. J. Hematol. , vol.45 , Issue.4 , pp. 298-303
    • Mohri, M.1    Oka, M.2    Aoki, Y.3    Gonda, Y.4    Hirata, S.5    Gomi, K.6    Kiyota, T.7    Sugihara, T.8    Yamamoto, S.9    Ishida, T.10
  • 57
    • 34147119744 scopus 로고    scopus 로고
    • The cytoprotective protein C pathway
    • Mosnier, L. O.; Zlokovic, B. V.; Griffin, J. H. The cytoprotective protein C pathway. Blood 109(8):3161-3172; 2007.
    • (2007) Blood , vol.109 , Issue.8 , pp. 3161-3172
    • Mosnier, L.O.1    Zlokovic, B.V.2    Griffin, J.H.3
  • 58
    • 0035707639 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by natural anticoagulants
    • Okajima, K. Regulation of inflammatory responses by natural anticoagulants. Immunol. Rev. 184:258-274; 2001.
    • (2001) Immunol. Rev. , vol.184 , pp. 258-274
    • Okajima, K.1
  • 59
    • 0242351640 scopus 로고    scopus 로고
    • Interactions between coagulation and inflammation
    • Opal, S. M. Interactions between coagulation and inflammation. Scand. J. Infect. Dis. 35(9):545-554; 2003.
    • (2003) Scand. J. Infect. Dis. , vol.35 , Issue.9 , pp. 545-554
    • Opal, S.M.1
  • 60
    • 0019861825 scopus 로고
    • Functional properties of an endothelial cell cofactor for thrombin-catalyzed activation of protein C
    • Owen, W. G.; Esmon, C. T. Functional properties of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. J. Biol. Chem. 256(11):5532-5535; 1981.
    • (1981) J. Biol. Chem. , vol.256 , Issue.11 , pp. 5532-5535
    • Owen, W.G.1    Esmon, C.T.2
  • 61
    • 0036263218 scopus 로고    scopus 로고
    • Inhibition of thrombin aborgates the instant blood-mediated inflammatory reaction triggered by isolated human islets: Possible application of the thrombin inhibitor melagatran in clinical islet transplantation
    • Ozmen, L.; Ekdahl, K. N.; Elgue, G.; Larsson, R.; Korsgren, O.; Nilsson, B. Inhibition of thrombin aborgates the instant blood-mediated inflammatory reaction triggered by isolated human islets: Possible application of the thrombin inhibitor melagatran in clinical islet transplantation. Diabetes 51(6):1779-1784; 2002.
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1779-1784
    • Ozmen, L.1    Ekdahl, K.N.2    Elgue, G.3    Larsson, R.4    Korsgren, O.5    Nilsson, B.6
  • 62
    • 33845513582 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: Results of a phase III, randomized, double-blind clinical trial
    • Saito, H.; Maruyama, I.; Shimazaki, S.; Yamamoto, Y.; Aikawa, N.; Ohno, R.; Hirayama, A.; Matsuda, T.; Asakura, H.; Nakashima, M.; Aoki, N. Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial. J. Thromb. Haemost. 5(1):31-41; 2007.
    • (2007) J. Thromb. Haemost. , vol.5 , Issue.1 , pp. 31-41
    • Saito, H.1    Maruyama, I.2    Shimazaki, S.3    Yamamoto, Y.4    Aikawa, N.5    Ohno, R.6    Hirayama, A.7    Matsuda, T.8    Asakura, H.9    Nakashima, M.10    Aoki, N.11
  • 64
    • 0028966594 scopus 로고
    • Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft
    • Shapiro, A. M.; Lakey, J. R.; Rajotte, R. V. Portal vein thrombosis after transplantation of partially purified pancreatic islets in a combined human liver/islet allograft. Transplantation 59:1060-1063; 1995.
    • (1995) Transplantation , vol.59 , pp. 1060-1063
    • Shapiro, A.M.1    Lakey, J.R.2    Rajotte, R.V.3
  • 65
    • 55749115786 scopus 로고    scopus 로고
    • Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response
    • Shi, C. S.; Shi, G. Y.; Hsiao, S. M.; Kao, Y. C.; Kuo, K. L.; Ma, C. Y.; Kuo, C. H.; Chang, B. I.; Chang, C. F.; Lin, C. H.; Wong, C. H.; Wu, H. L. Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response. Blood 112(9):3661-3670; 2008.
    • (2008) Blood , vol.112 , Issue.9 , pp. 3661-3670
    • Shi, C.S.1    Shi, G.Y.2    Hsiao, S.M.3    Kao, Y.C.4    Kuo, K.L.5    Ma, C.Y.6    Kuo, C.H.7    Chang, B.I.8    Chang, C.F.9    Lin, C.H.10    Wong, C.H.11    Wu, H.L.12
  • 67
    • 0034064131 scopus 로고    scopus 로고
    • Neuroprotection by recombinant thrombomodulin
    • Taoka, Y.; Okajima, K.; Uchiba, M.; Johno, M. Neuroprotection by recombinant thrombomodulin. Thromb. Haemost. 83(3):462-468; 2000.
    • (2000) Thromb. Haemost. , vol.83 , Issue.3 , pp. 462-468
    • Taoka, Y.1    Okajima, K.2    Uchiba, M.3    Johno, M.4
  • 68
    • 54949115420 scopus 로고    scopus 로고
    • Protective effects of activated protein C in sepsis
    • Toltl, L. J.; Swystun, L. L.; Pepler, L.; Liaw, P. C. Protective effects of activated protein C in sepsis. Thromb. Haemost. 100(4):582-592; 2008.
    • (2008) Thromb. Haemost. , vol.100 , Issue.4 , pp. 582-592
    • Toltl, L.J.1    Swystun, L.L.2    Pepler, L.3    Liaw, P.C.4
  • 69
    • 0026775230 scopus 로고
    • Functional domains of membrane-bound human thrombomodulin. EGF-like domains four to six and the serine/threonine-rich domain are required for cofactor activity
    • Tsiang, M.; Lentz, S. R.; Sadler, J. E. Functional domains of membrane-bound human thrombomodulin. EGF-like domains four to six and the serine/threonine-rich domain are required for cofactor activity. J. Biol. Chem. 267(9):6164-6170; 1992.
    • (1992) J. Biol. Chem. , vol.267 , Issue.9 , pp. 6164-6170
    • Tsiang, M.1    Lentz, S.R.2    Sadler, J.E.3
  • 70
    • 0030658104 scopus 로고    scopus 로고
    • rhs-TM prevents ET-induced increase in pulmonary vascular permeability through protein C activation
    • Uchiba, M.; Okajima, K.; Murakami, K.; Johno, M.; Mohri, M.; Okabe, H.; Takatsuki, K. rhs-TM prevents ET-induced increase in pulmonary vascular permeability through protein C activation. Am. J. Physiol. 273(4 Pt. 1):L889-894; 1997.
    • (1997) Am. J. Physiol. , vol.273 , Issue.4 PART. 1
    • Uchiba, M.1    Okajima, K.2    Murakami, K.3    Johno, M.4    Mohri, M.5    Okabe, H.6    Takatsuki, K.7
  • 71
    • 0029819270 scopus 로고    scopus 로고
    • Recombinant thrombomodulin prevents endotoxin-induced lung injury in rats by inhibiting leukocyte activation
    • Uchiba, M.; Okajima, K.; Murakami, K.; Johno, M.; Okabe, H.; Takatsuki, K. Recombinant thrombomodulin prevents endotoxin-induced lung injury in rats by inhibiting leukocyte activation. Am. J. Physiol. 271(3 Pt. 1):L470-475; 1996.
    • (1996) Am. J. Physiol. , vol.271 , Issue.3 PART. 1
    • Uchiba, M.1    Okajima, K.2    Murakami, K.3    Johno, M.4    Okabe, H.5    Takatsuki, K.6
  • 73
    • 3943060904 scopus 로고    scopus 로고
    • Thrombomodulin-protein C-EPCR system: Integrated to regulate coagulation and inflammation
    • Van de Wouwer, M.; Collen, D.; Conway, E. M. Thrombomodulin-protein C-EPCR system: integrated to regulate coagulation and inflammation. Arterioscler. Thromb. Vasc. Biol. 24(8):1374-1383; 2004.
    • (2004) Arterioscler. Thromb. Vasc. Biol. , vol.24 , Issue.8 , pp. 1374-1383
    • Van De Wouwer, M.1    Collen, D.2    Conway, E.M.3
  • 76
    • 34250364079 scopus 로고    scopus 로고
    • Pancreatic islet transplantation, what has been achieved since Edmonton break-through
    • discussion 32-43
    • Witkowski, P.; Zakai, S. B.; Rana, A.; Sledzinski, Z.; Hardy, M. A. Pancreatic islet transplantation, what has been achieved since Edmonton break-through. Ann. Transplant. 11(2):5-13; discussion 32-43; 2006.
    • (2006) Ann. Transplant. , vol.11 , Issue.2 , pp. 5-13
    • Witkowski, P.1    Zakai, S.B.2    Rana, A.3    Sledzinski, Z.4    Hardy, M.A.5
  • 77
    • 0028271718 scopus 로고
    • The role of nitric oxide in IL-1 beta-mediated dysfunction of rodent islets of Langerhans. Implications for the function of intrahepatic islet grafts
    • Xenos, E. S.; Stevens, R. B.; Sutherland, D. E.; Lokeh, A.; Ansite, J. D.; Casanova, D.; Gores, P. F.; Platt, J. L. The role of nitric oxide in IL-1 beta-mediated dysfunction of rodent islets of Langerhans. Implications for the function of intrahepatic islet grafts. Transplantation 57(8):1208-1212; 1994.
    • (1994) Transplantation , vol.57 , Issue.8 , pp. 1208-1212
    • Xenos, E.S.1    Stevens, R.B.2    Sutherland, D.E.3    Lokeh, A.4    Ansite, J.D.5    Casanova, D.6    Gores, P.F.7    Platt, J.L.8
  • 78
    • 33644870417 scopus 로고    scopus 로고
    • Liver ischemia contributes to early islet failure following intraportal transplantation: Benefits of liver ischemic-preconditioning
    • Yin, D.; Ding, J. W.; Shen, J.; Ma, L.; Hara, M.; Chong, A. S. Liver ischemia contributes to early islet failure following intraportal transplantation: Benefits of liver ischemic-preconditioning. Am. J. Transplant. 6(1):60-68; 2006.
    • (2006) Am. J. Transplant. , vol.6 , Issue.1 , pp. 60-68
    • Yin, D.1    Ding, J.W.2    Shen, J.3    Ma, L.4    Hara, M.5    Chong, A.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.