메뉴 건너뛰기




Volumn 5, Issue SUPPL. 2, 2001, Pages

The normal role of Activated Protein C in maintaining homeostasis and its relevance to critical illness

Author keywords

Activated Protein C; Coagulation; Endothelial cell Protein C receptor (EPCR); Inflammation, thrombomodulin

Indexed keywords

PROTEIN C; THROMBOMODULIN;

EID: 0035222641     PISSN: 13648535     EISSN: None     Source Type: Journal    
DOI: 10.1186/cc1333     Document Type: Article
Times cited : (66)

References (23)
  • 1
    • 0027424531 scopus 로고
    • Cell mediated events that control blood coagulation and vascular injury
    • Esmon C: Cell mediated events that control blood coagulation and vascular injury. Ann Rev Cell Devel Biol 1993, 9:1-26.
    • (1993) Ann Rev Cell Devel Biol , vol.9 , pp. 1-26
    • Esmon, C.1
  • 3
    • 24344446880 scopus 로고    scopus 로고
    • Natural anticoagulants and their pathways
    • Edited by Uprichard ACG, Gallagher KP. Heidelberg: Springer-Verlag
    • Esmon CT: Natural anticoagulants and their pathways. In: Antithrombotics (Handbook of Experiemental Pharmacology, vol 132. Edited by Uprichard ACG, Gallagher KP. Heidelberg: Springer-Verlag; 1999:447-476.
    • (1999) Antithrombotics Handbook of Experiemental Pharmacology , vol.132 , pp. 447-476
    • Esmon, C.T.1
  • 4
    • 0027943163 scopus 로고
    • Identification, cloning and regulation of a novel endothelial cell protein C/activated protein C receptor
    • Fukudome K, Esmon CT: Identification, cloning and regulation of a novel endothelial cell protein C/activated protein C receptor. J Biol Chem 1994, 269:26486-26491.
    • (1994) J Biol Chem , vol.269 , pp. 26486-26491
    • Fukudome, K.1    Esmon, C.T.2
  • 5
    • 0034059213 scopus 로고    scopus 로고
    • The endothelial cell protein C receptor
    • Esmon CT: The endothelial cell protein C receptor. Thromb Haemost 2000, 83:639-643.
    • (2000) Thromb Haemost , vol.83 , pp. 639-643
    • Esmon, C.T.1
  • 6
    • 0020370172 scopus 로고
    • Use of endothelium cultured on microcarriers as a model for the microcirculation
    • Busch C, Cancilla P, DeBault L, Goldsmith J, Owen W: Use of endothelium cultured on microcarriers as a model for the microcirculation. Lab Invest 1982, 47:498-504..
    • (1982) Lab Invest , vol.47 , pp. 498-504
    • Busch, C.1    Cancilla, P.2    DeBault, L.3    Goldsmith, J.4    Owen, W.5
  • 8
    • 0032956187 scopus 로고    scopus 로고
    • Infectious purpura fulminans: Diagnosis and treatment
    • Smith OP, White B: Infectious purpura fulminans: diagnosis and treatment Br J Haematol 1999, 104:202-207.
    • (1999) Br J Haematol , vol.104 , pp. 202-207
    • Smith, O.P.1    White, B.2
  • 9
    • 0031971176 scopus 로고    scopus 로고
    • Inflammation and thrombosis: Mutual regulation by protein C
    • Esmon CT: Inflammation and thrombosis: mutual regulation by protein C. The Immunologist 1998, 6:84-89.
    • (1998) The Immunologist , vol.6 , pp. 84-89
    • Esmon, C.T.1
  • 13
    • 0021958273 scopus 로고
    • Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity
    • Sakata Y, Curriden S, Lawrence D, Griffin JH, Loskutoff DJ: Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity. Proc Natl Acad Sci USA 1985, 82:1121-1125.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 1121-1125
    • Sakata, Y.1    Curriden, S.2    Lawrence, D.3    Griffin, J.H.4    Loskutoff, D.J.5
  • 14
    • 0029895009 scopus 로고    scopus 로고
    • TAFI or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex
    • Bajzar L, Morser J, Nesheim M: TAFI or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex. J Biol Chem 1996, 271:16603-16608.
    • (1996) J Biol Chem , vol.271 , pp. 16603-16608
    • Bajzar, L.1    Morser, J.2    Nesheim, M.3
  • 15
    • 0029044322 scopus 로고
    • Purification and characterization of TAFI, a thrombin-activable fibrinolysis inhibitor
    • Bajzar L, Manuel R, Nesheim ME: Purification and characterization of TAFI, a thrombin-activable fibrinolysis inhibitor. J Biol Chem 1995, 270:14477-14484.
    • (1995) J Biol Chem , vol.270 , pp. 14477-14484
    • Bajzar, L.1    Manuel, R.2    Nesheim, M.E.3
  • 16
    • 0032519883 scopus 로고    scopus 로고
    • Activated protein C reduces the severity of compression-induced spinal cord injury in rats by inhibiting activation of leukocytes
    • Taoka Y, Okajima K, Uchiba M, Murakami K, Harada N, Johno M, Naruo M: Activated protein C reduces the severity of compression-induced spinal cord injury in rats by inhibiting activation of leukocytes. J Neurosci 1998, 18:1393-1398.
    • (1998) J Neurosci , vol.18 , pp. 1393-1398
    • Taoka, Y.1    Okajima, K.2    Uchiba, M.3    Murakami, K.4    Harada, N.5    Johno, M.6    Naruo, M.7
  • 17
    • 0034660464 scopus 로고    scopus 로고
    • Activated protein C reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation
    • Mizutani A, Okajima K, Uchiba M, Noguchi T: Activated protein C reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation. Blood 2000, 95:3781-3787.
    • (2000) Blood , vol.95 , pp. 3781-3787
    • Mizutani, A.1    Okajima, K.2    Uchiba, M.3    Noguchi, T.4
  • 18
    • 24344493019 scopus 로고    scopus 로고
    • London: ReMedica Publishing; in press
    • Esmon CT: Activated Protein C. London: ReMedica Publishing; 2001:in press.
    • (2001) Activated Protein C
    • Esmon, C.T.1
  • 19
    • 0034668005 scopus 로고    scopus 로고
    • The soluble endothelial protein C receptor binds to activated neutrophils: Involvement of proteinase-3 and CD11b/CD18
    • Kurosawa S, Esmon CT, Stearns-Kurosawa DJ: The soluble endothelial protein C receptor binds to activated neutrophils: involvement of proteinase-3 and CD11b/CD18. J Immunol 2000, 165:4697-4703.
    • (2000) J Immunol , vol.165 , pp. 4697-4703
    • Kurosawa, S.1    Esmon, C.T.2    Stearns-Kurosawa, D.J.3
  • 20
    • 0033880884 scopus 로고    scopus 로고
    • Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor κB (NF-κB) and tumour necrosis factor α (TNF-α) production in the THP-1 monocytic cell line
    • White B, Schmidt M, Murphy C, Livingstone W, O'Toole D, Lawler M, O'Neill L, Kelleher D, Schwarz HP, Smith OP: Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor κB (NF-κB) and tumour necrosis factor α (TNF-α) production in the THP-1 monocytic cell line. Br J Haematol 2000, 110:130-134.
    • (2000) Br J Haematol , vol.110 , pp. 130-134
    • White, B.1    Schmidt, M.2    Murphy, C.3    Livingstone, W.4    O'Toole, D.5    Lawler, M.6    O'Neill, L.7    Kelleher, D.8    Schwarz, H.P.9    Smith, O.P.10
  • 21
    • 0029626658 scopus 로고
    • Binding of activated protein C to a specific receptor on human mononuclear phagocytes inhibits intracellular calcium signaling and monocyte-dependent proliferative responses
    • Hancock WW, Grey ST, Hau L, Akalin E, Orthner C, Sayegh MH, Salem HH: Binding of activated protein C to a specific receptor on human mononuclear phagocytes inhibits intracellular calcium signaling and monocyte-dependent proliferative responses. Transplantation 1995, 60:1525-1532.
    • (1995) Transplantation , vol.60 , pp. 1525-1532
    • Hancock, W.W.1    Grey, S.T.2    Hau, L.3    Akalin, E.4    Orthner, C.5    Sayegh, M.H.6    Salem, H.H.7
  • 22
    • 0034698261 scopus 로고    scopus 로고
    • Activated protein C suppresses tissue factor expression on U937 cells in the endothelial protein C receptor-dependent manner
    • Shu F, Kobayashi H, Fukudome K, Tsuneyoshi N, Kimoto M, Terao T: Activated protein C suppresses tissue factor expression on U937 cells in the endothelial protein C receptor-dependent manner. FEBS Lett 2000, 477:208-212.
    • (2000) FEBS Lett , vol.477 , pp. 208-212
    • Shu, F.1    Kobayashi, H.2    Fukudome, K.3    Tsuneyoshi, N.4    Kimoto, M.5    Terao, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.