메뉴 건너뛰기




Volumn 35, Issue 12, 2010, Pages 2199-2207

Translocation of the serine protease Omi/HtrA2 from mitochondria into the cytosol upon seizure-induced hippocampal injury in the neonatal rat brain

Author keywords

Cell death; Omi HtrA2; Seizures; Status epilepticus; XIAP

Indexed keywords

CASPASE 3; LITHIUM; PILOCARPINE; SERINE PROTEINASE OMI; X LINKED INHIBITOR OF APOPTOSIS;

EID: 78651303005     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-010-0322-0     Document Type: Article
Times cited : (15)

References (31)
  • 1
    • 0033925325 scopus 로고    scopus 로고
    • Purification and use of recombinant inhibitor of apoptosis proteins as caspase inhibitors
    • 1:CAS:528:DC%2BD3cXls1yitbo%3D 10.1016/S0076-6879(00)22015-6 10914012
    • QL Deveraux K Welsh JC Reed 2000 Purification and use of recombinant inhibitor of apoptosis proteins as caspase inhibitors Meth Enzymol 322 154 156 1:CAS:528:DC%2BD3cXls1yitbo%3D 10.1016/S0076-6879(00)22015-6 10914012
    • (2000) Meth Enzymol , vol.322 , pp. 154-156
    • Deveraux, Q.L.1    Welsh, K.2    Reed, J.C.3
  • 2
    • 0037427441 scopus 로고    scopus 로고
    • Mammalian mitochondrial IAP binding proteins
    • 1:CAS:528:DC%2BD3sXjt1Kisrc%3D 10.1016/S0006-291X(03)00622-3 12729584
    • DL Vaux J Silke 2003 Mammalian mitochondrial IAP binding proteins Biochem Biophys Res Commun 304 499 504 1:CAS:528:DC%2BD3sXjt1Kisrc%3D 10.1016/S0006-291X(03)00622-3 12729584
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 499-504
    • Vaux, D.L.1    Silke, J.2
  • 4
    • 9644272539 scopus 로고    scopus 로고
    • Regulation of XIAP and Smac/DIABLO in the rat hippocampus following transient forebrain ischemia
    • 1:CAS:528:DC%2BD2cXhtVagsr7O 10.1016/j.neuint.2004.07.009 15567514
    • MD Siegelin LS Kossatz J Winckler A Rami 2005 Regulation of XIAP and Smac/DIABLO in the rat hippocampus following transient forebrain ischemia Neurochem Int 46 41 51 1:CAS:528:DC%2BD2cXhtVagsr7O 10.1016/j.neuint.2004.07.009 15567514
    • (2005) Neurochem Int , vol.46 , pp. 41-51
    • Siegelin, M.D.1    Kossatz, L.S.2    Winckler, J.3    Rami, A.4
  • 5
    • 26944489976 scopus 로고    scopus 로고
    • Induction and redistribution of the XAF1, antagonist of XIAP in the rat brain after transient focal ischemia
    • 1:CAS:528:DC%2BD2MXhtFCjs7fO 10.1016/j.nbd.2005.04.006 15905097
    • M Siegelin O Touzani J Toutain P Liston A Rami 2005 Induction and redistribution of the XAF1, antagonist of XIAP in the rat brain after transient focal ischemia Neurobiol Dis 20 509 518 1:CAS:528:DC%2BD2MXhtFCjs7fO 10.1016/j.nbd.2005.04.006 15905097
    • (2005) Neurobiol Dis , vol.20 , pp. 509-518
    • Siegelin, M.1    Touzani, O.2    Toutain, J.3    Liston, P.4    Rami, A.5
  • 6
    • 46449095702 scopus 로고    scopus 로고
    • Exploiting endogenous anti-apoptotic proteins for novel therapeutic strategies in cerebral ischemia
    • 1:CAS:528:DC%2BD1cXosVymurs%3D 10.1016/j.pneurobio.2008.04.003 18511172
    • A Rami I Bechmann J Stehle 2008 Exploiting endogenous anti-apoptotic proteins for novel therapeutic strategies in cerebral ischemia Prog Neurobiol 85 273 296 1:CAS:528:DC%2BD1cXosVymurs%3D 10.1016/j.pneurobio.2008.04.003 18511172
    • (2008) Prog Neurobiol , vol.85 , pp. 273-296
    • Rami, A.1    Bechmann, I.2    Stehle, J.3
  • 7
    • 2542632121 scopus 로고    scopus 로고
    • Oxidative stress is associated with XIAP and Smac/DIABLO signaling pathways in mouse brains after transient focal cerebral ischemia
    • 1:CAS:528:DC%2BD2cXktFyku78%3D 10.1161/01.STR.0000128416.28778.7a 15118177
    • A Saito T Hayashi S Okuno T Nishi PH Chan 2004 Oxidative stress is associated with XIAP and Smac/DIABLO signaling pathways in mouse brains after transient focal cerebral ischemia Stroke 35 1443 1448 1:CAS:528: DC%2BD2cXktFyku78%3D 10.1161/01.STR.0000128416.28778.7a 15118177
    • (2004) Stroke , vol.35 , pp. 1443-1448
    • Saito, A.1    Hayashi, T.2    Okuno, S.3    Nishi, T.4    Chan, P.H.5
  • 8
    • 0038722727 scopus 로고    scopus 로고
    • Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis
    • 1:CAS:528:DC%2BD3sXkvFSisrc%3D 10.1101/gad.1097903 12815069
    • QH Yang R Church-Hajduk J Ren ML Newton C Du 2003 Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis Genes Dev 17 1487 1496 1:CAS:528:DC%2BD3sXkvFSisrc%3D 10.1101/gad.1097903 12815069
    • (2003) Genes Dev , vol.17 , pp. 1487-1496
    • Yang, Q.H.1    Church-Hajduk, R.2    Ren, J.3    Newton, M.L.4    Du, C.5
  • 9
    • 4344624526 scopus 로고    scopus 로고
    • Intramitochondrial serine protease activity of Omi/HtrA2 is required for caspase-independent cell death of human neutrophils
    • 10.1038/sj.cdd.4401409
    • E Blink NA Maianski ES Alnemri AS Zervos D Roos TW Kuijpers 2003 Intramitochondrial serine protease activity of Omi/HtrA2 is required for caspase-independent cell death of human neutrophils Cell Death Differ 11 937 949 10.1038/sj.cdd.4401409
    • (2003) Cell Death Differ , vol.11 , pp. 937-949
    • Blink, E.1    Maianski, N.A.2    Alnemri, E.S.3    Zervos, A.S.4    Roos, D.5    Kuijpers, T.W.6
  • 10
    • 0037022922 scopus 로고    scopus 로고
    • Apoptosis: Letting slip the dogs of war
    • 10.1016/S0960-9822(02)00736-4
    • BB Wolf DR Green 2003 Apoptosis: letting slip the dogs of war Curr Biol 12 177 179 10.1016/S0960-9822(02)00736-4
    • (2003) Curr Biol , vol.12 , pp. 177-179
    • Wolf, B.B.1    Green, D.R.2
  • 12
    • 33845380541 scopus 로고    scopus 로고
    • The serine protease Omi/HtrA2 is involved in XIAP cleavage and in neuronal cell death following focal cerebral ischemia/reperfusion
    • 1:CAS:528:DC%2BD28Xht12msrnK 10.1016/j.neuint.2006.07.018 16978742
    • J Althaus MD Siegelin F Dehghani L Cilenti AS Zervos A Rami 2007 The serine protease Omi/HtrA2 is involved in XIAP cleavage and in neuronal cell death following focal cerebral ischemia/reperfusion Neurochem Int 50 172 180 1:CAS:528:DC%2BD28Xht12msrnK 10.1016/j.neuint.2006.07.018 16978742
    • (2007) Neurochem Int , vol.50 , pp. 172-180
    • Althaus, J.1    Siegelin, M.D.2    Dehghani, F.3    Cilenti, L.4    Zervos, A.S.5    Rami, A.6
  • 13
    • 0032531738 scopus 로고    scopus 로고
    • Patterns of status epilepticus-induced neuronal injury during development and long-term consequences
    • 1:CAS:528:DyaK1cXms1ehurs%3D 9763481
    • DH Sankar H Shin A Liu A Mazarati Pereira de Vasconcelos CG Wasterlain 1998 Patterns of status epilepticus-induced neuronal injury during development and long-term consequences J Neurosci 18 8382 8393 1:CAS:528:DyaK1cXms1ehurs%3D 9763481
    • (1998) J Neurosci , vol.18 , pp. 8382-8393
    • Sankar, D.H.1    Shin, H.2    Liu, A.3    Mazarati, A.4    De Vasconcelos Pereira5    Wasterlain, C.G.6
  • 14
    • 0015309163 scopus 로고
    • Modification of seizure activity by electrical stimulation II. Motor seizure
    • 1:STN:280:DyaE387gvFCltg%3D%3D 10.1016/0013-4694(72)90177-0 4110397
    • RJ Racine 1972 Modification of seizure activity by electrical stimulation II. Motor seizure Electroencephalogr Clin Neurophysiol 32 281 294 1:STN:280:DyaE387gvFCltg%3D%3D 10.1016/0013-4694(72)90177-0 4110397
    • (1972) Electroencephalogr Clin Neurophysiol , vol.32 , pp. 281-294
    • Racine, R.J.1
  • 15
    • 0037154781 scopus 로고    scopus 로고
    • Differential induction of p53 in immature and adult rat brain following lithium-pilocarpine status epilepticus
    • 1:CAS:528:DC%2BD38Xht1ahsb8%3D 10.1016/S0006-8993(01)03359-5 11844486
    • Z Tan R Sankar D Shin N Sun H Liu CG Wasterlain SS Schreiber 2002 Differential induction of p53 in immature and adult rat brain following lithium-pilocarpine status epilepticus Brain Res 928 187 193 1:CAS:528:DC%2BD38Xht1ahsb8%3D 10.1016/S0006-8993(01)03359-5 11844486
    • (2002) Brain Res , vol.928 , pp. 187-193
    • Tan, Z.1    Sankar, R.2    Shin, D.3    Sun, N.4    Liu, H.5    Wasterlain, C.G.6    Schreiber, S.S.7
  • 16
    • 0037418292 scopus 로고    scopus 로고
    • Hypoxic neuronal necrosis: Protein synthesis-independent activation of a cell death program
    • 1:CAS:528:DC%2BD3sXitVaitLY%3D 10.1073/pnas.0530113100 12606726
    • J Niquet RA Baldwin SG Allen DG Fujikawa CG Wasterlain 2003 Hypoxic neuronal necrosis: protein synthesis-independent activation of a cell death program Proc Natl Acad Sci USA 100 2825 2830 1:CAS:528:DC%2BD3sXitVaitLY%3D 10.1073/pnas.0530113100 12606726
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2825-2830
    • Niquet, J.1    Baldwin, R.A.2    Allen, S.G.3    Fujikawa, D.G.4    Wasterlain, C.G.5
  • 17
    • 33746932314 scopus 로고    scopus 로고
    • Hypoxia in presence of blockers of excitotoxicity induces a caspase-dependent neuronal necrosis
    • 1:CAS:528:DC%2BD28Xms1elsrg%3D 10.1016/j.neuroscience.2006.03.073 16697116
    • J Niquet AllenSG SeoDW CG Wasterlain 2006 Hypoxia in presence of blockers of excitotoxicity induces a caspase-dependent neuronal necrosis Neuroscience 141 77 86 1:CAS:528:DC%2BD28Xms1elsrg%3D 10.1016/j.neuroscience.2006.03.073 16697116
    • (2006) Neuroscience , vol.141 , pp. 77-86
    • Niquet, J.1    Allensg, S.2    Wasterlain, C.G.3
  • 18
    • 72749092838 scopus 로고    scopus 로고
    • Vulnerability of postnatal hippocampal neurons to seizures varies regionally with their maturational stage
    • 1:CAS:528:DC%2BC3cXos1Gj 10.1016/j.nbd.2009.10.019 19879360
    • ML Lopez-Meraz CG Wasterlain L Rocha S Allen J Niquet 2010 Vulnerability of postnatal hippocampal neurons to seizures varies regionally with their maturational stage Neurobiol Dis 37 394 402 1:CAS:528:DC%2BC3cXos1Gj 10.1016/j.nbd.2009.10.019 19879360
    • (2010) Neurobiol Dis , vol.37 , pp. 394-402
    • Lopez-Meraz, M.L.1    Wasterlain, C.G.2    Rocha, L.3    Allen, S.4    Niquet, J.5
  • 19
    • 34249805412 scopus 로고    scopus 로고
    • Status epilepticus triggers caspase-3 activation and necrosis in the immature rat brain
    • 10.1111/j.1528-1167.2007.01102.x 17441993
    • J Niquet S Auvin M Archie DW Seo S Allen R Sankar CW Wasterlain 2007 Status epilepticus triggers caspase-3 activation and necrosis in the immature rat brain Epilepsia 48 1203 1206 10.1111/j.1528-1167.2007.01102.x 17441993
    • (2007) Epilepsia , vol.48 , pp. 1203-1206
    • Niquet, J.1    Auvin, S.2    Archie, M.3    Seo, D.W.4    Allen, S.5    Sankar, R.6    Wasterlain, C.W.7
  • 20
    • 0034905394 scopus 로고    scopus 로고
    • XIAP: Apoptotic brake and promising therapeutic
    • 1:CAS:528:DC%2BD3MXmsF2qu7g%3D 10.1023/A:1011379307472 11445667
    • M Holcik H Gibson RG Korneluk 2001 XIAP: apoptotic brake and promising therapeutic Apoptosis 6 253 261 1:CAS:528:DC%2BD3MXmsF2qu7g%3D 10.1023/A:1011379307472 11445667
    • (2001) Apoptosis , vol.6 , pp. 253-261
    • Holcik, M.1    Gibson, H.2    Korneluk, R.G.3
  • 21
    • 0034785591 scopus 로고    scopus 로고
    • A serine protease, Omi/HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
    • 1:CAS:528:DC%2BD3MXnslGmtrk%3D 10.1016/S1097-2765(01)00341-0 11583623
    • Y Suzuki Y Imai H Nakayama K Takahashi K Takio R Takahashi 2001 A serine protease, Omi/HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death Mol Cell 8 613 621 1:CAS:528:DC%2BD3MXnslGmtrk%3D 10.1016/S1097-2765(01)00341-0 11583623
    • (2001) Mol Cell , vol.8 , pp. 613-621
    • Suzuki, Y.1    Imai, Y.2    Nakayama, H.3    Takahashi, K.4    Takio, K.5    Takahashi, R.6
  • 22
    • 18544386724 scopus 로고    scopus 로고
    • Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
    • 1:CAS:528:DC%2BD38XjslGhug%3D%3D 10.1074/jbc.M109721200 11606597
    • R Hegde SM Srinivasula Z Zhang R Wassell R Mukattash L Cilenti G DuBois Y Lazebnik AS Zervos T Fernandes-Alnemri ES Alnemri 2002 Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction J Biol Chem 277 432 438 1:CAS:528:DC%2BD38XjslGhug%3D%3D 10.1074/jbc.M109721200 11606597
    • (2002) J Biol Chem , vol.277 , pp. 432-438
    • Hegde, R.1    Srinivasula, S.M.2    Zhang, Z.3    Wassell, R.4    Mukattash, R.5    Cilenti, L.6    Dubois, G.7    Lazebnik, Y.8    Zervos, A.S.9    Fernandes-Alnemri, T.10    Alnemri, E.S.11
  • 24
    • 0037562009 scopus 로고    scopus 로고
    • Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2
    • 1:CAS:528:DC%2BD3sXit1KgtL8%3D 10.1074/jbc.M212819200 12529364
    • L Cilenti Y Lee S Hess S Srinivasula KM Park D Junqueira H Davis JV Bonventre ES Alnemri AS Zervos 2003 Characterization of a novel and specific inhibitor for the pro-apoptotic protease Omi/HtrA2 J Biol Chem 278 11489 11494 1:CAS:528:DC%2BD3sXit1KgtL8%3D 10.1074/jbc.M212819200 12529364
    • (2003) J Biol Chem , vol.278 , pp. 11489-11494
    • Cilenti, L.1    Lee, Y.2    Hess, S.3    Srinivasula, S.4    Park, K.M.5    Junqueira, D.6    Davis, H.7    Bonventre, J.V.8    Alnemri, E.S.9    Zervos, A.S.10
  • 25
    • 0034723201 scopus 로고    scopus 로고
    • Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia
    • 1:CAS:528:DC%2BD3cXpvFCgsw%3D%3D 10.1074/jbc.275.4.2581 10644717
    • L Faccio C Fusco A Chen S Martinotti JV Bonventre AS Zervos 2000 Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia J Biol Chem 275 2581 2588 1:CAS:528:DC%2BD3cXpvFCgsw%3D%3D 10.1074/jbc.275.4.2581 10644717
    • (2000) J Biol Chem , vol.275 , pp. 2581-2588
    • Faccio, L.1    Fusco, C.2    Chen, A.3    Martinotti, S.4    Bonventre, J.V.5    Zervos, A.S.6
  • 27
    • 0342684483 scopus 로고    scopus 로고
    • Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy
    • 1:CAS:528:DyaK2sXmtleiu7s%3D 10.1016/S0169-328X(97)00162-9 9406913
    • F Gillardon B Böttiger B Schmitz M Zimmermann KA Hossmann 1997 Activation of CPP-32 protease in hippocampal neurons following ischemia and epilepsy Mol Brain Res 50 16 22 1:CAS:528:DyaK2sXmtleiu7s%3D 10.1016/S0169-328X(97)00162-9 9406913
    • (1997) Mol Brain Res , vol.50 , pp. 16-22
    • Gillardon, F.1    Böttiger, B.2    Schmitz, B.3    Zimmermann, M.4    Hossmann, K.A.5
  • 28
    • 0037072873 scopus 로고    scopus 로고
    • Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases
    • 1:CAS:528:DC%2BD38Xnt1Squ70%3D 10.1074/jbc.M205167200 12097334
    • CM Troy JE Friedman WJ Friedman 2002 Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases J Biol Chem 277 34295 34302 1:CAS:528:DC%2BD38Xnt1Squ70%3D 10.1074/jbc.M205167200 12097334
    • (2002) J Biol Chem , vol.277 , pp. 34295-34302
    • Troy, C.M.1    Friedman, J.E.2    Friedman, W.J.3
  • 29
    • 14744289621 scopus 로고    scopus 로고
    • Expressiontime course and spatial distribution of activated caspase-3 after experimental status epilepticus: Contribution of delayed neuronalcell death to seizure-induced neuronal injury
    • 1:CAS:528:DC%2BD2MXhvFynsLc%3D 10.1016/j.nbd.2004.10.025 15755684
    • J Weise T Engelhorn A Dorfler S Aker M Bahr A Hufnagel 2005 Expressiontime course and spatial distribution of activated caspase-3 after experimental status epilepticus: contribution of delayed neuronalcell death to seizure-induced neuronal injury Neurobiol Dis 18 582 590 1:CAS:528: DC%2BD2MXhvFynsLc%3D 10.1016/j.nbd.2004.10.025 15755684
    • (2005) Neurobiol Dis , vol.18 , pp. 582-590
    • Weise, J.1    Engelhorn, T.2    Dorfler, A.3    Aker, S.4    Bahr, M.5    Hufnagel, A.6
  • 30
    • 0035888112 scopus 로고    scopus 로고
    • Domoic acid-induced neuronal damage in the rat hippocampus: Changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response
    • 1:CAS:528:DC%2BD3MXnsVyktLc%3D 10.1002/jnr.1210 11592113
    • C Ananth S Thameem Dheen P Gopalakrishnakone C Kaur 2001 Domoic acid-induced neuronal damage in the rat hippocampus: changes in apoptosis related genes (bcl-2, bax, caspase-3) and microglial response J Neurosci Res 66 177 190 1:CAS:528:DC%2BD3MXnsVyktLc%3D 10.1002/jnr.1210 11592113
    • (2001) J Neurosci Res , vol.66 , pp. 177-190
    • Ananth, C.1    Thameem Dheen, S.2    Gopalakrishnakone, P.3    Kaur, C.4
  • 31
    • 0036789084 scopus 로고    scopus 로고
    • Caspase-3 is not activated in seizure-induced neuronal necrosis with internucleosomal DNA cleavage
    • 1:CAS:528:DC%2BD38XnvVGgtrs%3D 10.1046/j.1471-4159.2002.01152.x 12358747
    • DG Fujikawa X Ke RB Trinidad SS Shinmei A Wu 2002 Caspase-3 is not activated in seizure-induced neuronal necrosis with internucleosomal DNA cleavage J Neurochem 83 229 240 1:CAS:528:DC%2BD38XnvVGgtrs%3D 10.1046/j.1471-4159.2002.01152.x 12358747
    • (2002) J Neurochem , vol.83 , pp. 229-240
    • Fujikawa, D.G.1    Ke, X.2    Trinidad, R.B.3    Shinmei, S.S.4    Wu, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.