Apoptosis: Letting slip the dogs of war

Current Biology

Volumn 12, Issue 5, 2002, Pages

  Wolf, Beni B ^a   Green, Douglas R ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANIS FAMILIARIS;

CASPASE; INHIBITOR OF APOPTOSIS PROTEIN; INSECT PROTEIN; MITOCHONDRIAL PROTEIN; PROTEIN; SERINE PROTEINASE; SERINE PROTEINASE OMI;

AMINO ACID SEQUENCE; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; ENZYME ACTIVATION; GENETICS; METABOLISM; PHYSIOLOGY; REVIEW; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CASPASES; ENZYME ACTIVATION; INHIBITOR OF APOPTOSIS PROTEINS; INSECT PROTEINS; MITOCHONDRIAL PROTEINS; MODELS, BIOLOGICAL; PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES;

EID: 0037022922     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00736-4     Document Type: Review

References (20)

1. Apoptotic pathways: Paper wraps stone blunts scissors
2. Suicidal tendencies: Apoptotic cell death by caspase family proteinases
3. A serine protease, HtrA2, is released from mitochondria and interacts with XIAP, inducing cell death
4. The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
5. HtrA2 promotes cell death through its serine protease activity and its ability to antagonize inhibitor of apoptosis proteins
6. Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts IAP-caspase interaction
7. Two CD95 (Apo-1/Fas) signaling pathways
8. Inhibitor of apoptosis proteins and their inhibitors: IAPs and other BIRPs
9. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
10. Identification of DIABOLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
11. A conserved XIAP-interacting motif in caspase-9 and Smac/Diabolo regulates caspase activity and apoptosis
12. An emerging blueprint for apoptosis in Drosophila
13. Inhibitor of apoptosis proteins physically interact with and block apoptosis induced by Drosophila proteins HID and GRIM
14. Induction of apoptosis by Drosophila reaper, hid, and grim through inhibition of IAP function
15. The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity
16. A functional role for death proteases in s-Myc- and c-Myc-mediated apoptosis
17. Requirements for proteolysis during apoptosis
18. Activation of pro-caspase-7 by serine proteases includes non-cannonical specificity
19. A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein
20. Characterization of a novel human serine protease that has extensive homology to bacterial heat shock endoprotease HtrA and is regulated by kidney ischemia