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Volumn 3, Issue 3, 2010, Pages 219-229

Clearance of Amyloid-β peptide across the choroid plexus in alzheimer's disease

Author keywords

Aging; Alzheimer's disease; Amyloid beta; Choroid plexus; Epithelial cells; Megalin; Tight junctions; Vesicular transport proteins

Indexed keywords

ADRENOMEDULLIN; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ARGININE; BASIC FIBROBLAST GROWTH FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CLUSTERIN; ENDOTHELIN 1; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MEGALIN; NERVE GROWTH FACTOR; NEUROTROPHIN 3; NEUROTROPHIN 4; PREALBUMIN; PROSTAGLANDIN D SYNTHASE; SCATTER FACTOR; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 2; SOMATOMEDIN BINDING PROTEIN 6; TRANSFERRIN; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; VASCULOTROPIN; VASOPRESSIN;

EID: 78651273605     PISSN: 18746098     EISSN: 18746128     Source Type: Journal    
DOI: 10.2174/1874609811003030219     Document Type: Review
Times cited : (67)

References (102)
  • 1
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease:progress and problems on the road to therapeutics. Science 2002; 297(5580): 353-6.
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 2
    • 4444276735 scopus 로고    scopus 로고
    • Clearance of Alzheimer's Abetapeptide: The many roads to perdition
    • Tanzi RE, Moir RD, Wagner SL. Clearance of Alzheimer's Abetapeptide: the many roads to perdition. Neuron 2004; 43(5): 605-8.
    • (2004) Neuron , vol.43 , Issue.5 , pp. 605-608
    • Tanzi, R.E.1    Moir, R.D.2    Wagner, S.L.3
  • 3
  • 4
    • 4544322402 scopus 로고    scopus 로고
    • The aging brain: Morphomolecular senescenceof cortical circuits
    • Hof PR, Morrison JH. The aging brain: morphomolecular senescenceof cortical circuits. Trends Neurosci 2004; 27(10): 607-13.
    • (2004) Trends Neurosci , vol.27 , Issue.10 , pp. 607-613
    • Hof, P.R.1    Morrison, J.H.2
  • 5
    • 2542475986 scopus 로고    scopus 로고
    • Clearing amyloid through the blood-brain barrier
    • Zlokovic BV. Clearing amyloid through the blood-brain barrier. JNeurochem 2004; 89(4): 807-11.
    • (2004) JNeurochem , vol.89 , Issue.4 , pp. 807-811
    • Zlokovic, B.V.1
  • 6
    • 2442594971 scopus 로고    scopus 로고
    • Early-onset and robust cerebral microvascular accumulation ofamyloid beta-protein in transgenic mice expressing low levels of avasculotropic Dutch/Iowa mutant form of amyloid beta-proteinprecursor
    • Davis J, Xu F, Deane R, Romanov G, Previti ML, Zeigler K, et al. Early-onset and robust cerebral microvascular accumulation ofamyloid beta-protein in transgenic mice expressing low levels of avasculotropic Dutch/Iowa mutant form of amyloid beta-proteinprecursor. J Biol Chem 2004; 279(19): 20296-306.
    • (2004) J Biol Chem , vol.279 , Issue.19 , pp. 20296-20306
    • Davis, J.1    Xu, F.2    Deane, R.3    Romanov, G.4    Previti, M.L.5    Zeigler, K.6
  • 7
    • 7644225312 scopus 로고    scopus 로고
    • RAGE (yin) versus LRP (yang)balance regulates alzheimer amyloid beta-peptide clearance throughtransport across the blood-brain barrier
    • Deane R, Wu Z, Zlokovic BV. RAGE (yin) versus LRP (yang)balance regulates alzheimer amyloid beta-peptide clearance throughtransport across the blood-brain barrier. Stroke 2004; 35(11 Suppl 1): 2628-31.
    • (2004) Stroke , vol.35 , Issue.11 SUPPL 1 , pp. 2628-2631
    • Deane, R.1    Wu, Z.2    Zlokovic, B.V.3
  • 8
    • 28044466172 scopus 로고    scopus 로고
    • Choroidplexus megalin is involved in neuroprotection by serum insulinlikegrowth factor I
    • Carro E, Spuch C, Trejo JL, Antequera D, Torres-Aleman I. Choroidplexus megalin is involved in neuroprotection by serum insulinlikegrowth factor I. J Neurosci 2005; 25(47): 10884-93.
    • (2005) J Neurosci , vol.25 , Issue.47 , pp. 10884-10893
    • Carro, E.1    Spuch, C.2    Trejo, J.L.3    Antequera, D.4    Torres-Aleman, I.5
  • 9
    • 0029920929 scopus 로고    scopus 로고
    • Glycoprotein 330/megalin: Probable role inreceptor-mediated transport of apolipoprotein J alone and in a complexwith Alzheimer disease amyloid beta at the blood-brain andblood-cerebrospinal fluid barriers
    • Zlokovic BV, Martel CL, Matsubara E, McComb JG, Zheng G, McCluskey RT, et al. Glycoprotein 330/megalin: probable role inreceptor-mediated transport of apolipoprotein J alone and in a complexwith Alzheimer disease amyloid beta at the blood-brain andblood-cerebrospinal fluid barriers. Proc Natl Acad Sci USA 1996; 93(9): 4229-34.
    • (1996) Proc Natl Acad Sci USA , vol.93 , Issue.9 , pp. 4229-4234
    • Zlokovic, B.V.1    Martel, C.L.2    Matsubara, E.3    McComb, J.G.4    Zheng, G.5    McCluskey, R.T.6
  • 10
    • 0030753654 scopus 로고    scopus 로고
    • Interaction of apolipoprotein J-amyloid beta-peptide complexwith low density lipoprotein receptor-related protein-2/megalin. Amechanism to prevent pathological accumulation of amyloid betapeptide
    • Hammad SM, Ranganathan S, Loukinova E, Twal WO, Argraves WS. Interaction of apolipoprotein J-amyloid beta-peptide complexwith low density lipoprotein receptor-related protein-2/megalin. Amechanism to prevent pathological accumulation of amyloid betapeptide. J Biol Chem 1997; 272(30): 18644-9.
    • (1997) J Biol Chem , vol.272 , Issue.30 , pp. 18644-18649
    • Hammad, S.M.1    Ranganathan, S.2    Loukinova, E.3    Twal, W.O.4    Argraves, W.S.5
  • 11
    • 1542778656 scopus 로고    scopus 로고
    • Choroid plexus, aging of the brain, and Alzheimer's disease
    • Serot JM, Bene MC, Faure GC. Choroid plexus, aging of the brain, and Alzheimer's disease. Front Biosci 2003; 8: s515-21.
    • (2003) Front Biosci , vol.8
    • Serot, J.M.1    Bene, M.C.2    Faure, G.C.3
  • 12
    • 0035148720 scopus 로고    scopus 로고
    • Ageing choroid plexus-cerebrospinal fluid system
    • Preston JE. Ageing choroid plexus-cerebrospinal fluid system. Microsc Res Tech 2001; 52(1): 31-7.
    • (2001) Microsc Res Tech , vol.52 , Issue.1 , pp. 31-37
    • Preston, J.E.1
  • 13
    • 0035151602 scopus 로고    scopus 로고
    • Choroid plexus: Target forpolypeptides and site of their synthesis
    • Chodobski A, Szmydynger-Chodobska J. Choroid plexus: target forpolypeptides and site of their synthesis. Microsc Res Tech 2001; 52(1): 65-82.
    • (2001) Microsc Res Tech , vol.52 , Issue.1 , pp. 65-82
    • Chodobski, A.1    Szmydynger-Chodobska, J.2
  • 14
    • 0037081177 scopus 로고    scopus 로고
    • Cell proliferation and differentiation fromependymal, subependymal and choroid plexus cells in response tostroke in rats
    • Li Y, Chen J, Chopp M. Cell proliferation and differentiation fromependymal, subependymal and choroid plexus cells in response tostroke in rats. J Neurol Sci 2002; 193(2): 137-46.
    • (2002) J Neurol Sci , vol.193 , Issue.2 , pp. 137-146
    • Li, Y.1    Chen, J.2    Chopp, M.3
  • 15
    • 0035126559 scopus 로고    scopus 로고
    • Grafting of choroid plexus ependymal cellspromotes the growth of regenerating axons in the dorsal funiculusof rat spinal cord: A preliminary report
    • Ide C, Kitada M, Chakrabortty S, Taketomi M, Matsumoto N, Kikukawa S, et al. Grafting of choroid plexus ependymal cellspromotes the growth of regenerating axons in the dorsal funiculusof rat spinal cord: a preliminary report. Exp Neurol 2001; 167(2): 242-51.
    • (2001) Exp Neurol , vol.167 , Issue.2 , pp. 242-251
    • Ide, C.1    Kitada, M.2    Chakrabortty, S.3    Taketomi, M.4    Matsumoto, N.5    Kikukawa, S.6
  • 16
    • 0014930828 scopus 로고
    • The choroid plexus: A historical review
    • Dohrmann GJ. The choroid plexus: a historical review. Brain Res 1970; 18(2): 197-218.
    • (1970) Brain Res , vol.18 , Issue.2 , pp. 197-218
    • Dohrmann, G.J.1
  • 17
    • 0014872949 scopus 로고
    • Human choroid plexus: A light and electronmicroscopic study
    • Dohrmann GJ, Bucy PC. Human choroid plexus: a light and electronmicroscopic study. J Neurosurg 1970; 33(5): 506-16.
    • (1970) J Neurosurg , vol.33 , Issue.5 , pp. 506-516
    • Dohrmann, G.J.1    Bucy, P.C.2
  • 18
    • 0025126177 scopus 로고
    • A morphometric study on the development ofthe lateral ventricle choroid plexus, choroid plexus capillaries andventricular ependyma in the rat
    • Keep RF, Jones HC. A morphometric study on the development ofthe lateral ventricle choroid plexus, choroid plexus capillaries andventricular ependyma in the rat. Brain Res Dev Brain Res 1990; 56(1): 47-53.
    • (1990) Brain Res Dev Brain Res , vol.56 , Issue.1 , pp. 47-53
    • Keep, R.F.1    Jones, H.C.2
  • 22
    • 1442352660 scopus 로고    scopus 로고
    • Aquaporin-1 deletionreduces osmotic water permeability and cerebrospinal fluid production
    • Oshio K, Song Y, Verkman AS, Manley GT. Aquaporin-1 deletionreduces osmotic water permeability and cerebrospinal fluid production. Acta Neurochir Suppl 2003; 86: 525-8.
    • (2003) Acta Neurochir Suppl , vol.86 , pp. 525-528
    • Oshio, K.1    Song, Y.2    Verkman, A.S.3    Manley, G.T.4
  • 23
    • 0035921150 scopus 로고    scopus 로고
    • Dynamics of brain-derived proteins in cerebrospinalfluid
    • Reiber H. Dynamics of brain-derived proteins in cerebrospinalfluid. Clin Chim Acta 2001; 310(2): 173-86.
    • (2001) Clin Chim Acta , vol.310 , Issue.2 , pp. 173-186
    • Reiber, H.1
  • 25
    • 0035151478 scopus 로고    scopus 로고
    • Human choroid plexus growth factors: What are theimplications for CSF dynamics in Alzheimer's disease?
    • Stopa EG, Berzin TM, Kim S, Song P, Kuo-LeBlanc V, Rodriguez-Wolf M, et al. Human choroid plexus growth factors: What are theimplications for CSF dynamics in Alzheimer's disease? Exp Neurol 2001; 167(1): 40-7.
    • (2001) Exp Neurol , vol.167 , Issue.1 , pp. 40-47
    • Stopa, E.G.1    Berzin, T.M.2    Kim, S.3    Song, P.4    Kuo-LeBlanc, V.5    Rodriguez-Wolf, M.6
  • 26
    • 0032904490 scopus 로고    scopus 로고
    • Distribution andretrograde transport of trophic factors in the central nervous system: Functional implications for the treatment of neurodegenerativediseases
    • Mufson EJ, Kroin JS, Sendera TJ, Sobreviela T. Distribution andretrograde transport of trophic factors in the central nervous system:functional implications for the treatment of neurodegenerativediseases. Prog Neurobiol 1999; 57(4): 451-84.
    • (1999) Prog Neurobiol , vol.57 , Issue.4 , pp. 451-484
    • Mufson, E.J.1    Kroin, J.S.2    Sendera, T.J.3    Sobreviela, T.4
  • 27
    • 44349084306 scopus 로고    scopus 로고
    • Transplants of encapsulated rat choroid plexus cells exert neuroprotectionin a rodent model of Huntington's disease
    • Borlongan CV, Thanos CG, Skinner SJ, Geaney M, Emerich DF. Transplants of encapsulated rat choroid plexus cells exert neuroprotectionin a rodent model of Huntington's disease. Cell Transplant 2008; 16(10): 987-92.
    • (2008) Cell Transplant , vol.16 , Issue.10 , pp. 987-992
    • Borlongan, C.V.1    Thanos, C.G.2    Skinner, S.J.3    Geaney, M.4    Emerich, D.F.5
  • 28
    • 70449520476 scopus 로고    scopus 로고
    • Potential of choroid plexus epithelialcell grafts for neuroprotection in Huntington's disease: What remainsbefore considering clinical trials
    • Emerich DF, Borlongan CV. Potential of choroid plexus epithelialcell grafts for neuroprotection in Huntington's disease: what remainsbefore considering clinical trials. Neurotox Res 2009; 15(3): 205-11.
    • (2009) Neurotox Res , vol.15 , Issue.3 , pp. 205-211
    • Emerich, D.F.1    Borlongan, C.V.2
  • 29
    • 0031843633 scopus 로고    scopus 로고
    • Thepolarity of choroid plexus epithelial cells in vitro is improved in serum-free medium
    • Hakvoort A, Haselbach M, Wegener J, Hoheisel D, Galla HJ. Thepolarity of choroid plexus epithelial cells in vitro is improved in serum-free medium. J Neurochem 1998; 71(3): 1141-50.
    • (1998) J Neurochem , vol.71 , Issue.3 , pp. 1141-1150
    • Hakvoort, A.1    Haselbach, M.2    Wegener, J.3    Hoheisel, D.4    Galla, H.J.5
  • 30
    • 0035542982 scopus 로고    scopus 로고
    • Differentiation of choroid plexus ependymal cells into astrocytesafter grafting into the pre-lesioned spinal cord in mice
    • Kitada M, Chakrabortty S, Matsumoto N, Taketomi M, Ide C. Differentiation of choroid plexus ependymal cells into astrocytesafter grafting into the pre-lesioned spinal cord in mice. Glia 2001; 36(3): 364-74.
    • (2001) Glia , vol.36 , Issue.3 , pp. 364-374
    • Kitada, M.1    Chakrabortty, S.2    Matsumoto, N.3    Taketomi, M.4    Ide, C.5
  • 31
    • 4243691501 scopus 로고    scopus 로고
    • Altered cerebrospinalfluid secretion rate and 125I-labelled II-amyloid transport inthe aged sheep isolated perfused choroid plexus
    • Wilson MR, Preston JE, Thomas SA, Segal MB. Altered cerebrospinalfluid secretion rate and 125I-labelled II-amyloid transport inthe aged sheep isolated perfused choroid plexus. J Physiol 1999; 515P: 7-8P.
    • (1999) J Physiol , vol.515 P
    • Wilson, M.R.1    Preston, J.E.2    Thomas, S.A.3    Segal, M.B.4
  • 32
    • 84924184981 scopus 로고    scopus 로고
    • Choroid plexus andageing in rats: A morphometric and ultrastructural study
    • Serot JM, Foliguet B, Bene MC, Faure GC. Choroid plexus andageing in rats: a morphometric and ultrastructural study. Eur J Neurosci 2001; 14(5): 794-8.
    • (2001) Eur J Neurosci , vol.14 , Issue.5 , pp. 794-798
    • Serot, J.M.1    Foliguet, B.2    Bene, M.C.3    Faure, G.C.4
  • 33
    • 0023936781 scopus 로고
    • An ultrastructural study of the choroid plexus of agedmice
    • Sturrock RR. An ultrastructural study of the choroid plexus of agedmice. Anat Anz 1988; 165(5): 379-85.
    • (1988) Anat Anz , vol.165 , Issue.5 , pp. 379-385
    • Sturrock, R.R.1
  • 34
    • 0342545852 scopus 로고    scopus 로고
    • Morphological alterationsof the choroid plexus in late-onset Alzheimer's disease
    • Serot JM, Bene MC, Foliguet B, Faure GC. Morphological alterationsof the choroid plexus in late-onset Alzheimer's disease. ActaNeuropathol 2000; 99(2): 105-8.
    • (2000) ActaNeuropathol , vol.99 , Issue.2 , pp. 105-108
    • Serot, J.M.1    Bene, M.C.2    Foliguet, B.3    Faure, G.C.4
  • 35
    • 0033583934 scopus 로고    scopus 로고
    • Biondi ring tangles in thechoroid plexus of Alzheimer's disease and normal aging brains: Aquantitative study
    • Wen GY, Wisniewski HM, Kascsak RJ. Biondi ring tangles in thechoroid plexus of Alzheimer's disease and normal aging brains: aquantitative study. Brain Res 1999; 832(1-2): 40-6.
    • (1999) Brain Res , vol.832 , Issue.1-2 , pp. 40-46
    • Wen, G.Y.1    Wisniewski, H.M.2    Kascsak, R.J.3
  • 36
    • 0014792190 scopus 로고
    • Human choroid plexus: Morphologicand histochemical alterations with age
    • Shuangshoti S, Netsky MG. Human choroid plexus: morphologicand histochemical alterations with age. Am J Anat 1970; 128(1): 73-95.
    • (1970) Am J Anat , vol.128 , Issue.1 , pp. 73-95
    • Shuangshoti, S.1    Netsky, M.G.2
  • 40
    • 0025957221 scopus 로고
    • Analysis of brain and cerebrospinal fluid volumeswith MR imaging: Impact on PET data correction for atrophy. PartII. Aging and Alzheimer dementia
    • Tanna NK, Kohn MI, Horwich DN, Jolles PR, Zimmerman RA, Alves WM, et al. Analysis of brain and cerebrospinal fluid volumeswith MR imaging: impact on PET data correction for atrophy. PartII. Aging and Alzheimer dementia. Radiology 1991; 178(1): 123-30.
    • (1991) Radiology , vol.178 , Issue.1 , pp. 123-130
    • Tanna, N.K.1    Kohn, M.I.2    Horwich, D.N.3    Jolles, P.R.4    Zimmerman, R.A.5    Alves, W.M.6
  • 41
    • 0031797783 scopus 로고    scopus 로고
    • Curly fiber and tangle-like inclusions in the ependyma andchoroid plexus--a pathogenetic relationship with the cortical Alzheimer-type changes?
    • Miklossy J, Kraftsik R, Pillevuit O, Lepori D, Genton C, Bosman FT. Curly fiber and tangle-like inclusions in the ependyma andchoroid plexus--a pathogenetic relationship with the cortical Alzheimer-type changes? J Neuropathol Exp Neurol 1998; 57(12): 1202-12.
    • (1998) J Neuropathol Exp Neurol , vol.57 , Issue.12 , pp. 1202-1212
    • Miklossy, J.1    Kraftsik, R.2    Pillevuit, O.3    Lepori, D.4    Genton, C.5    Bosman, F.T.6
  • 42
    • 0027937687 scopus 로고
    • Comparative immunohistochemicalcharacteristics of human choroid plexus in vascular and Alzheimer'sdementia
    • Serot JM, Bene MC, Faure GC. Comparative immunohistochemicalcharacteristics of human choroid plexus in vascular and Alzheimer'sdementia. Hum Pathol 1994; 25(11): 1185-90.
    • (1994) Hum Pathol , vol.25 , Issue.11 , pp. 1185-1190
    • Serot, J.M.1    Bene, M.C.2    Faure, G.C.3
  • 44
    • 4344577078 scopus 로고
    • La cysternographie isotopique dans les détériorations mentaleset les démences du sujet âgé
    • Serot JM, Bertrand A, Penin F, Hocquard C, Mietkiewicz MC, Cunt C. La cysternographie isotopique dans les détériorations mentaleset les démences du sujet âgé. Med Hyg 1987; 36: 1928-30.
    • (1987) Med Hyg , vol.36 , pp. 1928-1930
    • Serot, J.M.1    Bertrand, A.2    Penin, F.3    Hocquard, C.4    Mietkiewicz, M.C.5    Cunt, C.6
  • 45
    • 0035960650 scopus 로고    scopus 로고
    • The cerebrospinal fluid production rate is reducedin dementia of the Alzheimer's type
    • Silverberg GD, Heit G, Huhn S, Jaffe RA, Chang SD, Bronte-Stewart H, et al. The cerebrospinal fluid production rate is reducedin dementia of the Alzheimer's type. Neurology 2001; 57(10): 1763-6.
    • (2001) Neurology , vol.57 , Issue.10 , pp. 1763-1766
    • Silverberg, G.D.1    Heit, G.2    Huhn, S.3    Jaffe, R.A.4    Chang, S.D.5    Bronte-Stewart, H.6
  • 46
    • 0031661418 scopus 로고    scopus 로고
    • Cerebrospinal fluid productionis normal in Down syndrome
    • Atack JR, Rapoport SI, Schapiro MB. Cerebrospinal fluid productionis normal in Down syndrome. Neurobiol Aging 1998; 19(4): 307-9.
    • (1998) Neurobiol Aging , vol.19 , Issue.4 , pp. 307-309
    • Atack, J.R.1    Rapoport, S.I.2    Schapiro, M.B.3
  • 47
    • 0025197214 scopus 로고
    • Vitamin B12 levels in serum and cerebrospinal fluid of people withAlzheimer's disease
    • Ikeda T, Furukawa Y, Mashimoto S, Takahashi K, Yamada M. Vitamin B12 levels in serum and cerebrospinal fluid of people withAlzheimer's disease. Acta Psychiatr Scand 1990; 82(4): 327-9.
    • (1990) Acta Psychiatr Scand , vol.82 , Issue.4 , pp. 327-329
    • Ikeda, T.1    Furukawa, Y.2    Mashimoto, S.3    Takahashi, K.4    Yamada, M.5
  • 48
    • 27444437550 scopus 로고    scopus 로고
    • Homocysteine and methylmalonic acid concentrations incerebrospinal fluid: Relation with age and Alzheimer's disease
    • Serot JM, Barbe F, Arning E, Bottiglieri T, Franck P, Montagne P, et al. Homocysteine and methylmalonic acid concentrations incerebrospinal fluid: relation with age and Alzheimer's disease. JNeurol Neurosurg Psychiatry 2005; 76(11): 1585-7.
    • (2005) JNeurol Neurosurg Psychiatry , vol.76 , Issue.11 , pp. 1585-1587
    • Serot, J.M.1    Barbe, F.2    Arning, E.3    Bottiglieri, T.4    Franck, P.5    Montagne, P.6
  • 49
    • 0036224435 scopus 로고    scopus 로고
    • The effect of increased concentrationsof homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer'sdisease
    • Selley ML, Close DR, Stern SE. The effect of increased concentrationsof homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer'sdisease. Neurobiol Aging 2002; 23(3): 383-8.
    • (2002) Neurobiol Aging , vol.23 , Issue.3 , pp. 383-388
    • Selley, M.L.1    Close, D.R.2    Stern, S.E.3
  • 50
    • 0028177379 scopus 로고
    • Concentrations of alpha-tocopherol and its quinone derivative incerebrospinal fluid from patients with vascular dementia of theBinswanger type and Alzheimer type dementia
    • Tohgi H, Abe T, Nakanishi M, Hamato F, Sasaki K, Takahashi S. Concentrations of alpha-tocopherol and its quinone derivative incerebrospinal fluid from patients with vascular dementia of theBinswanger type and Alzheimer type dementia. Neurosci Lett 1994; 174(1): 73-6.
    • (1994) Neurosci Lett , vol.174 , Issue.1 , pp. 73-76
    • Tohgi, H.1    Abe, T.2    Nakanishi, M.3    Hamato, F.4    Sasaki, K.5    Takahashi, S.6
  • 52
    • 0032933750 scopus 로고    scopus 로고
    • Increased DNA oxidationand decreased levels of repair products in Alzheimer's diseaseventricular CSF
    • Lovell MA, Gabbita SP, Markesbery WR. Increased DNA oxidationand decreased levels of repair products in Alzheimer's diseaseventricular CSF. J Neurochem 1999; 72(2): 771-6.
    • (1999) J Neurochem , vol.72 , Issue.2 , pp. 771-776
    • Lovell, M.A.1    Gabbita, S.P.2    Markesbery, W.R.3
  • 54
    • 0029680635 scopus 로고    scopus 로고
    • Early contribution of oxidativeglycation in Alzheimer disease
    • Smith MA, Tabaton M, Perry G. Early contribution of oxidativeglycation in Alzheimer disease. Neurosci Lett 1996; 217(2-3): 210-1.
    • (1996) Neurosci Lett , vol.217 , Issue.2-3 , pp. 210-211
    • Smith, M.A.1    Tabaton, M.2    Perry, G.3
  • 56
    • 0042611250 scopus 로고    scopus 로고
    • Alzheimer's disease--synergistic effects of glucose deficit, oxidativestress and advanced glycation endproducts
    • Münch G, Schinzel R, Loske C, Wong A, Durany N, Li JJ, et al. Alzheimer's disease--synergistic effects of glucose deficit, oxidativestress and advanced glycation endproducts. J Neural Transm 1998; 105(4-5): 439-61.
    • (1998) J Neural Transm , vol.105 , Issue.4-5 , pp. 439-461
    • Münch, G.1    Schinzel, R.2    Loske, C.3    Wong, A.4    Durany, N.5    Li, J.J.6
  • 58
    • 69949119382 scopus 로고    scopus 로고
    • Abeta accumulation in choroid plexus is associated withmitochondrial-induced apoptosis
    • [Epubahead of print]
    • Vargas T, Ugalde C, Spuch C, Antequera D, Moran MJ, Martin MA, et al. Abeta accumulation in choroid plexus is associated withmitochondrial-induced apoptosis. Neurobiol Aging 2008 [Epubahead of print].
    • (2008) Neurobiol Aging
    • Vargas, T.1    Ugalde, C.2    Spuch, C.3    Antequera, D.4    Moran, M.J.5    Martin, M.A.6
  • 59
    • 69949118812 scopus 로고    scopus 로고
    • Oxidativestress damage and oxidative stress responses in the choroidplexus in Alzheimer's disease
    • Perez-Gracia E, Blanco R, Carmona M, Carro E, Ferrer I. Oxidativestress damage and oxidative stress responses in the choroidplexus in Alzheimer's disease. Acta Neuropathol 2009; 118(4): 497-504.
    • (2009) Acta Neuropathol , vol.118 , Issue.4 , pp. 497-504
    • Perez-Gracia, E.1    Blanco, R.2    Carmona, M.3    Carro, E.4    Ferrer, I.5
  • 60
    • 13944276825 scopus 로고    scopus 로고
    • Twenty years of the Alzheimer's diseaseamyloid hypothesis: A genetic perspective
    • Tanzi RE, Bertram L. Twenty years of the Alzheimer's diseaseamyloid hypothesis: a genetic perspective. Cell 2005; 120(4): 545-55.
    • (2005) Cell , vol.120 , Issue.4 , pp. 545-555
    • Tanzi, R.E.1    Bertram, L.2
  • 61
    • 0035081475 scopus 로고    scopus 로고
    • Alzheimer's disease results from the cerebral accumulationand cytotoxicity of amyloid beta-protein
    • Selkoe DJ. Alzheimer's disease results from the cerebral accumulationand cytotoxicity of amyloid beta-protein. J Alzheimers Dis 2001; 3(1): 75-80.
    • (2001) J Alzheimers Dis , vol.3 , Issue.1 , pp. 75-80
    • Selkoe, D.J.1
  • 62
    • 33947191364 scopus 로고    scopus 로고
    • Pittsburgh compound B retention and verificationof amyloid deposition
    • Holtzman DM. Pittsburgh compound B retention and verificationof amyloid deposition. Arch Neurol 2007; 64(3): 315-6.
    • (2007) Arch Neurol , vol.64 , Issue.3 , pp. 315-316
    • Holtzman, D.M.1
  • 63
    • 0037703255 scopus 로고    scopus 로고
    • RAGE mediates amyloid-beta peptide transportacross the blood-brain barrier and accumulation in brain
    • Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, et al. RAGE mediates amyloid-beta peptide transportacross the blood-brain barrier and accumulation in brain. Nat Med 2003; 9(7): 907-13.
    • (2003) Nat Med , vol.9 , Issue.7 , pp. 907-913
    • Deane, R.1    Du Yan, S.2    Submamaryan, R.K.3    LaRue, B.4    Jovanovic, S.5    Hogg, E.6
  • 64
    • 4043061467 scopus 로고    scopus 로고
    • LRP/amyloid beta-peptide interaction mediates differential brainefflux of Abeta isoforms
    • Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, et al. LRP/amyloid beta-peptide interaction mediates differential brainefflux of Abeta isoforms. Neuron 2004; 43(3): 333-44.
    • (2004) Neuron , vol.43 , Issue.3 , pp. 333-344
    • Deane, R.1    Wu, Z.2    Sagare, A.3    Davis, J.4    Du Yan, S.5    Hamm, K.6
  • 65
    • 34247506244 scopus 로고    scopus 로고
    • Transport pathways for clearance of human Alzheimer'samyloid beta-peptide and apolipoproteins E and J in themouse central nervous system
    • Bell RD, Sagare AP, Friedman AE, Bedi GS, Holtzman DM, Deane R, et al. Transport pathways for clearance of human Alzheimer'samyloid beta-peptide and apolipoproteins E and J in themouse central nervous system. J Cereb Blood Flow Metab 2007; 27(5): 909-18.
    • (2007) J Cereb Blood Flow Metab , vol.27 , Issue.5 , pp. 909-918
    • Bell, R.D.1    Sagare, A.P.2    Friedman, A.E.3    Bedi, G.S.4    Holtzman, D.M.5    Deane, R.6
  • 66
    • 0034521392 scopus 로고    scopus 로고
    • Clearance of Alzheimer's amyloid-ss(1-40) peptide frombrain by LDL receptor-related protein-1 at the blood-brain barrier
    • Shibata M, Yamada S, Kumar SR, Calero M, Bading J, Frangione B, et al. Clearance of Alzheimer's amyloid-ss(1-40) peptide frombrain by LDL receptor-related protein-1 at the blood-brain barrier. JClin Invest 2000; 106(12): 1489-99.
    • (2000) JClin Invest , vol.106 , Issue.12 , pp. 1489-1499
    • Shibata, M.1    Yamada, S.2    Kumar, S.R.3    Calero, M.4    Bading, J.5    Frangione, B.6
  • 67
    • 0036917631 scopus 로고    scopus 로고
    • Serum insulin-like growth factor I regulates brain amyloid-betalevels
    • Carro E, Trejo JL, Gomez-Isla T, LeRoith D, Torres-Aleman I. Serum insulin-like growth factor I regulates brain amyloid-betalevels. Nat Med 2002; 8(12): 1390-7.
    • (2002) Nat Med , vol.8 , Issue.12 , pp. 1390-1397
    • Carro, E.1    Trejo, J.L.2    Gomez-Isla, T.3    LeRoith, D.4    Torres-Aleman, I.5
  • 68
    • 27644457417 scopus 로고    scopus 로고
    • The choroid plexus removes betaamyloidfrom brain cerebrospinal fluid
    • Crossgrove JS, Li GJ, Zheng W. The choroid plexus removes betaamyloidfrom brain cerebrospinal fluid. Exp Biol Med (Maywood)2005; 230(10): 771-6.
    • (2005) Exp Biol Med (Maywood) , vol.230 , Issue.10 , pp. 771-776
    • Crossgrove, J.S.1    Li, G.J.2    Zheng, W.3
  • 69
    • 0038038284 scopus 로고    scopus 로고
    • Alzheimer'sdisease, normal-pressure hydrocephalus, and senescentchanges in CSF circulatory physiology: A hypothesis
    • Silverberg GD, Mayo M, Saul T, Rubenstein E, McGuire D. Alzheimer'sdisease, normal-pressure hydrocephalus, and senescentchanges in CSF circulatory physiology: a hypothesis. Lancet Neurol 2003; 2(8): 506-11.
    • (2003) Lancet Neurol , vol.2 , Issue.8 , pp. 506-511
    • Silverberg, G.D.1    Mayo, M.2    Saul, T.3    Rubenstein, E.4    McGuire, D.5
  • 70
    • 0033178980 scopus 로고    scopus 로고
    • Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brainprotection toward xenobiotics
    • Strazielle N, Ghersi-Egea JF. Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brainprotection toward xenobiotics. J Neurosci 1999; 19(15): 6275-89.
    • (1999) J Neurosci , vol.19 , Issue.15 , pp. 6275-6289
    • Strazielle, N.1    Ghersi-Egea, J.F.2
  • 71
    • 0036361639 scopus 로고    scopus 로고
    • The blood-CSF barrier in culture. Developmentof a primary culture and transepithelial transport model from choroidalepithelial cells
    • Zheng W, Zhao Q. The blood-CSF barrier in culture. Developmentof a primary culture and transepithelial transport model from choroidalepithelial cells. Methods Mol Biol 2002; 188: 99-114.
    • (2002) Methods Mol Biol , vol.188 , pp. 99-114
    • Zheng, W.1    Zhao, Q.2
  • 72
    • 0032934627 scopus 로고    scopus 로고
    • Glycoprotein330/megalin (LRP-2) has low prevalence as mRNA andprotein in brain microvessels and choroid plexus
    • Chun JT, Wang L, Pasinetti GM, Finch CE, Zlokovic BV. Glycoprotein330/megalin (LRP-2) has low prevalence as mRNA andprotein in brain microvessels and choroid plexus. Exp Neurol 1999; 157(1): 194-201.
    • (1999) Exp Neurol , vol.157 , Issue.1 , pp. 194-201
    • Chun, J.T.1    Wang, L.2    Pasinetti, G.M.3    Finch, C.E.4    Zlokovic, B.V.5
  • 73
    • 1842633868 scopus 로고    scopus 로고
    • The role of insulin and insulin-likegrowth factor I in the molecular and cellular mechanisms underlyingthe pathology of Alzheimer's disease
    • Carro E, Torres-Aleman I. The role of insulin and insulin-likegrowth factor I in the molecular and cellular mechanisms underlyingthe pathology of Alzheimer's disease. Eur J Pharmacol 2004; 490(1-3): 127-33.
    • (2004) Eur J Pharmacol , vol.490 , Issue.1-3 , pp. 127-133
    • Carro, E.1    Torres-Aleman, I.2
  • 74
    • 0034814749 scopus 로고    scopus 로고
    • Phosphoinositide3-kinase inhibits megalin-mediated transcytosis of thyroglobulinacross thyroid epithelial cells at a post-sorting level
    • Marinò M, Chiovato L, Lisi S, Pinchera A, McCluskey RT. Phosphoinositide3-kinase inhibits megalin-mediated transcytosis of thyroglobulinacross thyroid epithelial cells at a post-sorting level. EurJ Endocrinol 2001; 145(4): 477-83.
    • (2001) EurJ Endocrinol , vol.145 , Issue.4 , pp. 477-483
    • Marinò, M.1    Chiovato, L.2    Lisi, S.3    Pinchera, A.4    McCluskey, R.T.5
  • 75
    • 0035940434 scopus 로고    scopus 로고
    • Megalin-dependent cubilin-mediated endocytosis isa major pathway for the apical uptake of transferrin in polarizedepithelia
    • Kozyraki R, Fyfe J, Verroust PJ, Jacobsen C, Dautry-Varsat A, Gburek J, et al. Megalin-dependent cubilin-mediated endocytosis isa major pathway for the apical uptake of transferrin in polarizedepithelia. Proc Natl Acad Sci USA 2001; 98(22): 12491-6.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.22 , pp. 12491-12496
    • Kozyraki, R.1    Fyfe, J.2    Verroust, P.J.3    Jacobsen, C.4    Dautry-Varsat, A.5    Gburek, J.6
  • 76
    • 0035902619 scopus 로고    scopus 로고
    • Peripheral anti-A beta antibody alters CNS andplasma A beta clearance and decreases brain A beta burden in amouse model of Alzheimer's disease
    • DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, Holtzman DM. Peripheral anti-A beta antibody alters CNS andplasma A beta clearance and decreases brain A beta burden in amouse model of Alzheimer's disease. Proc Natl Acad Sci USA2001; 98(15): 8850-5.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.15 , pp. 8850-8855
    • DeMattos, R.B.1    Bales, K.R.2    Cummins, D.J.3    Dodart, J.C.4    Paul, S.M.5    Holtzman, D.M.6
  • 77
    • 0141867783 scopus 로고    scopus 로고
    • Efflux of humanand mouse amyloid beta proteins 1-40 and 1-42 from brain: Impairmentin a mouse model of Alzheimer's disease
    • Banks WA, Robinson SM, Verma S, Morley JE. Efflux of humanand mouse amyloid beta proteins 1-40 and 1-42 from brain: impairmentin a mouse model of Alzheimer's disease. Neuroscience 2003; 121(2): 487-92.
    • (2003) Neuroscience , vol.121 , Issue.2 , pp. 487-492
    • Banks, W.A.1    Robinson, S.M.2    Verma, S.3    Morley, J.E.4
  • 78
    • 0030035294 scopus 로고    scopus 로고
    • Fate of cerebrospinal fluid-borne amyloid betapeptide: Rapid clearance into blood and appreciable accumulationby cerebral arteries
    • Ghersi-Egea JF, Gorevic PD, Ghiso J, Frangione B, Patlak CS, Fenstermacher JD. Fate of cerebrospinal fluid-borne amyloid betapeptide:rapid clearance into blood and appreciable accumulationby cerebral arteries. J Neurochem 1996; 67(2): 880-3.
    • (1996) J Neurochem , vol.67 , Issue.2 , pp. 880-883
    • Ghersi-Egea, J.F.1    Gorevic, P.D.2    Ghiso, J.3    Frangione, B.4    Patlak, C.S.5    Fenstermacher, J.D.6
  • 80
    • 42149122012 scopus 로고    scopus 로고
    • Functional role of lipoprotein receptors inAlzheimer's disease
    • Jaeger S, Pietrzik CU. Functional role of lipoprotein receptors inAlzheimer's disease. Curr Alzheimer Res 2008; 5(1): 15-25.
    • (2008) Curr Alzheimer Res , vol.5 , Issue.1 , pp. 15-25
    • Jaeger, S.1    Pietrzik, C.U.2
  • 81
    • 34247557490 scopus 로고    scopus 로고
    • The LDL receptor-relatedprotein (LRP) family: An old family of proteins with new physiologicalfunctions
    • May P, Woldt E, Matz RL, Boucher P. The LDL receptor-relatedprotein (LRP) family: an old family of proteins with new physiologicalfunctions. Ann Med 2007; 39(3): 219-28.
    • (2007) Ann Med , vol.39 , Issue.3 , pp. 219-228
    • May, P.1    Woldt, E.2    Matz, R.L.3    Boucher, P.4
  • 82
    • 0039516463 scopus 로고    scopus 로고
    • Cloning and sequencing of human gp330, a Ca(2+)-binding receptor with potential intracellular signaling properties
    • Hjälm G, Murray E, Crumley G, Harazim W, Lundgren S, Onyango I, et al. Cloning and sequencing of human gp330, a Ca(2+)-binding receptor with potential intracellular signaling properties. Eur J Biochem 1996; 239(1): 132-7.
    • (1996) Eur J Biochem , vol.239 , Issue.1 , pp. 132-137
    • Hjälm, G.1    Murray, E.2    Crumley, G.3    Harazim, W.4    Lundgren, S.5    Onyango, I.6
  • 83
    • 0028019068 scopus 로고
    • Complete cloningand sequencing of rat gp330/"megalin," a distinctive member ofthe low density lipoprotein receptor gene family
    • Saito A, Pietromonaco S, Loo AK, Farquhar MG. Complete cloningand sequencing of rat gp330/"megalin," a distinctive member ofthe low density lipoprotein receptor gene family. Proc Natl AcadSci USA 1994; 91(21): 9725-9.
    • (1994) Proc Natl AcadSci USA , vol.91 , Issue.21 , pp. 9725-9729
    • Saito, A.1    Pietromonaco, S.2    Loo, A.K.3    Farquhar, M.G.4
  • 84
    • 84984766757 scopus 로고    scopus 로고
    • Megalin and cubilin: Multifunctionalendocytic receptors
    • Christensen EI, Birn H. Megalin and cubilin: multifunctionalendocytic receptors. Nat Rev Mol Cell Biol 2002; 3(4): 256-66.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.4 , pp. 256-266
    • Christensen, E.I.1    Birn, H.2
  • 85
    • 0041975828 scopus 로고    scopus 로고
    • From holoprosencephaly toosteopathology: Role of multifunctional endocytic receptors in absorptiveepithelia
    • Müller D, Nykjaer A, Willnow TE. From holoprosencephaly toosteopathology: role of multifunctional endocytic receptors in absorptiveepithelia. Ann Med 2003; 35(5): 290-9.
    • (2003) Ann Med , vol.35 , Issue.5 , pp. 290-299
    • Müller, D.1    Nykjaer, A.2    Willnow, T.E.3
  • 86
    • 7744226396 scopus 로고    scopus 로고
    • Immunolocalization of cubilin, megalin, apolipoprotein J, and apolipoprotein A-I in the uterus andoviduct
    • Argraves WS, Morales CR. Immunolocalization of cubilin, megalin, apolipoprotein J, and apolipoprotein A-I in the uterus andoviduct. Mol Reprod Dev 2004; 69(4): 419-27.
    • (2004) Mol Reprod Dev , vol.69 , Issue.4 , pp. 419-427
    • Argraves, W.S.1    Morales, C.R.2
  • 87
    • 0034941332 scopus 로고    scopus 로고
    • Megalin- and cubilin-mediated endocytosisof protein-bound vitamins, lipids, and hormones in polarizedepithelia
    • Moestrup SK, Verroust PJ. Megalin- and cubilin-mediated endocytosisof protein-bound vitamins, lipids, and hormones in polarizedepithelia. Annu Rev Nutr 2001; 21: 407-28.
    • (2001) Annu Rev Nutr , vol.21 , pp. 407-428
    • Moestrup, S.K.1    Verroust, P.J.2
  • 88
    • 0037296697 scopus 로고    scopus 로고
    • Co-expression and interactionof cubilin and megalin in the adult male rat reproductive system
    • Van Praet O, Argraves WS, Morales CR. Co-expression and interactionof cubilin and megalin in the adult male rat reproductive system. Mol Reprod Dev 2003; 64(2): 129-35.
    • (2003) Mol Reprod Dev , vol.64 , Issue.2 , pp. 129-135
    • Van Praet, O.1    Argraves, W.S.2    Morales, C.R.3
  • 89
    • 0035195421 scopus 로고    scopus 로고
    • Cubilin and megalinexpression and their interaction in the rat intestine: Effect of thyroidectomy
    • Yammani RR, Seetharam S, Seetharam B. Cubilin and megalinexpression and their interaction in the rat intestine: effect of thyroidectomy. Am J Physiol Endocrinol Metab 2001; 281(5): E900-7.
    • (2001) Am J Physiol Endocrinol Metab , vol.281 , Issue.5
    • Yammani, R.R.1    Seetharam, S.2    Seetharam, B.3
  • 90
    • 0028067714 scopus 로고
    • Immunological localization of glycoprotein 330, low density lipoproteinreceptor related protein and 39 kDa receptor associated proteinin embryonic mouse tissues
    • Kounnas MZ, Haudenschild CC, Strickland DK, Argraves WS. Immunological localization of glycoprotein 330, low density lipoproteinreceptor related protein and 39 kDa receptor associated proteinin embryonic mouse tissues. In Vivo 1994; 8(3): 343-51.
    • (1994) In Vivo , vol.8 , Issue.3 , pp. 343-351
    • Kounnas, M.Z.1    Haudenschild, C.C.2    Strickland, D.K.3    Argraves, W.S.4
  • 91
    • 26644440897 scopus 로고    scopus 로고
    • Low-density lipoproteinreceptor-related protein (LRP)-2/megalin is transiently expressedin a subpopulation of neural progenitors in the embryonicmouse spinal cord
    • Wicher G, Larsson M, Rask L, Aldskogius H. Low-density lipoproteinreceptor-related protein (LRP)-2/megalin is transiently expressedin a subpopulation of neural progenitors in the embryonicmouse spinal cord. J Comp Neurol 2005; 492(2): 123-31.
    • (2005) J Comp Neurol , vol.492 , Issue.2 , pp. 123-131
    • Wicher, G.1    Larsson, M.2    Rask, L.3    Aldskogius, H.4
  • 92
    • 33645314067 scopus 로고    scopus 로고
    • Low density lipoprotein receptor-related protein-2/megalin is expressed in oligodendrocytes in the mouse spinalcord white matter
    • Wicher G, Larsson M, Fex Svenningsen A, Gyllencreutz E, Rask L, Aldskogius H. Low density lipoprotein receptor-related protein-2/megalin is expressed in oligodendrocytes in the mouse spinalcord white matter. J Neurosci Res 2006; 83(5): 864-73.
    • (2006) J Neurosci Res , vol.83 , Issue.5 , pp. 864-873
    • Wicher, G.1    Larsson, M.2    Fex Svenningsen, A.3    Gyllencreutz, E.4    Rask, L.5    Aldskogius, H.6
  • 93
    • 48249096748 scopus 로고    scopus 로고
    • Megalin is a receptor for albumin in astrocytesand is required for the synthesis of the neurotrophic factoroleic acid
    • Bento-Abreu A, Velasco A, Polo-Hernández E, Párez-Reyes PL, Tabernero A, Medina JM. Megalin is a receptor for albumin in astrocytesand is required for the synthesis of the neurotrophic factoroleic acid. J Neurochem 2008; 106(3): 1149-59.
    • (2008) J Neurochem , vol.106 , Issue.3 , pp. 1149-1159
    • Bento-Abreu, A.1    Velasco, A.2    Polo-Hernández, E.3    Párez-Reyes, P.L.4    Tabernero, A.5    Medina, J.M.6
  • 94
    • 37249056581 scopus 로고    scopus 로고
    • Metallothionein and a peptide modeled aftermetallothionein, EmtinB, induce neuronal differentiation and survivalthrough binding to receptors of the low-density lipoproteinreceptor family
    • Ambjørn M, Asmussen JW, Lindstam M, Gotfryd K, Jacobsen C, Kiselyov VV, et al. Metallothionein and a peptide modeled aftermetallothionein, EmtinB, induce neuronal differentiation and survivalthrough binding to receptors of the low-density lipoproteinreceptor family. J Neurochem 2008; 104(1): 21-37.
    • (2008) J Neurochem , vol.104 , Issue.1 , pp. 21-37
    • Ambjørn, M.1    Asmussen, J.W.2    Lindstam, M.3    Gotfryd, K.4    Jacobsen, C.5    Kiselyov, V.V.6
  • 95
    • 0030793522 scopus 로고    scopus 로고
    • Neuronal cell death in Alzheimer's disease correlates with apoE uptakeand intracellular Abeta stabilization
    • LaFerla FM, Troncoso JC, Strickland DK, Kawas CH, Jay G. Neuronal cell death in Alzheimer's disease correlates with apoE uptakeand intracellular Abeta stabilization. J Clin Invest 1997; 100(2): 310-20.
    • (1997) J Clin Invest , vol.100 , Issue.2 , pp. 310-320
    • LaFerla, F.M.1    Troncoso, J.C.2    Strickland, D.K.3    Kawas, C.H.4    Jay, G.5
  • 96
    • 1942453793 scopus 로고    scopus 로고
    • Potential role of the low-density lipoproteinreceptor family as mediators of cellular drug uptake
    • Chung NS, Wasan KM. Potential role of the low-density lipoproteinreceptor family as mediators of cellular drug uptake. Adv DrugDeliv Rev 2004; 56(9): 1315-34.
    • (2004) Adv DrugDeliv Rev , vol.56 , Issue.9 , pp. 1315-1334
    • Chung, N.S.1    Wasan, K.M.2
  • 97
    • 33646708967 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis of megalin: Linking urinary protein and gene regulation in proximal tubule?
    • Biemesderfer D. Regulated intramembrane proteolysis of megalin:linking urinary protein and gene regulation in proximal tubule? Kidney Int 2006; 69(10): 1717-21.
    • (2006) Kidney Int , vol.69 , Issue.10 , pp. 1717-1721
    • Biemesderfer, D.1
  • 98
    • 0037387838 scopus 로고    scopus 로고
    • Integration of endocytosis and signaltransduction by lipoprotein receptors
    • May P, Bock HH, Herz J. Integration of endocytosis and signaltransduction by lipoprotein receptors. Sci STKE 2003; 2003(176): PE12.
    • (2003) Sci STKE , vol.2003 , Issue.176
    • May, P.1    Bock, H.H.2    Herz, J.3
  • 99
    • 0038795645 scopus 로고    scopus 로고
    • Signals for sorting of transmembraneproteins to endosomes and lysosomes
    • Bonifacino JS, Traub LM. Signals for sorting of transmembraneproteins to endosomes and lysosomes. Annu Rev Biochem 2003; 72: 395-447.
    • (2003) Annu Rev Biochem , vol.72 , pp. 395-447
    • Bonifacino, J.S.1    Traub, L.M.2


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