Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics

Journal of Neuroscience

Volumn 19, Issue 15, 1999, Pages 6275-6289

  Strazielle, Nathalie ^b   Ghersi Egea, Jean François ^a  

^a UNIVERSITÉ LYON 1   (France)

^b NONE

Author keywords

Blood brain barrier; Brain protection; Choroid plexus epithelial cell culture; Drug metabolism; Glutathione S transferase; Multidrug resistance associated protein; UDP glucuronosyl transferase

Indexed keywords

1 NAPHTHOL; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; PREALBUMIN; PROBENECID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; XENOBIOTIC AGENT;

ANIMAL CELL; ARTICLE; BLOOD CEREBROSPINAL FLUID BARRIER; CHOROID PLEXUS; CONJUGATION; CONTROLLED STUDY; DRUG TRANSPORT; GLUTATHIONE METABOLISM; NEUROPROTECTION; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; TIGHT JUNCTION; XENOBIOTIC METABOLISM;

EID: 0033178980     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-15-06275.1999     Document Type: Article

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