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Volumn 8, Issue 1, 2011, Pages 69-82

Current perspective of stem cell therapies for cardiac regeneration

Author keywords

acute myocardial infarction; bone marrow derived cells; cardiac progenitor cells; embryonic stem cells; induced pluripotent stem cells; myocardial ischemia; skeletal myoblasts

Indexed keywords

ACUTE HEART INFARCTION; ADIPOSE TISSUE; ANGINA PECTORIS; ANGIOGENESIS; AUTOLOGOUS STEM CELL TRANSPLANTATION; CARDIAC REGENERATION; CARDIOMYOPATHY; CELL TRANSDIFFERENTIATION; CONGESTIVE HEART FAILURE; CORONARY ARTERY DISEASE; EMBRYONIC STEM CELL; ENDOTHELIAL PROGENITOR CELL; FUNCTIONAL STATUS; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE ISCHEMIA; HEMATOPOIETIC STEM CELL; HUMAN; ISCHEMIC CARDIOMYOPATHY; MESENCHYMAL STEM CELL; MYOBLAST; NONHUMAN; PLURIPOTENT STEM CELL; REVIEW; STEM CELL TRANSPLANTATION; TISSUE REGENERATION; UMBILICAL CORD BLOOD;

EID: 78650933990     PISSN: 14750708     EISSN: 1744831X     Source Type: Journal    
DOI: 10.2217/thy.10.81     Document Type: Review
Times cited : (1)

References (119)
  • 1
    • 33846345462 scopus 로고    scopus 로고
    • The double burden: Emerging epidemics and persistent problems
    • WHO, Geneva, Switzerland
    • Dean TJ, Creese A, Prentice T: The double burden: emerging epidemics and persistent problems. In: The World Health Report 1999. WHO, Geneva, Switzerland, 13 27 (1999).
    • (1999) The World Health Report 1999 , pp. 13-27
    • Dean, T.J.1    Creese, A.2    Prentice, T.3
  • 2
    • 57149134513 scopus 로고    scopus 로고
    • Long term trends in the incidence of heart failure after myocardial infarction
    • Velagaleti RS, Pencina MJ, Murabito JM et al. Long term trends in the incidence of heart failure after myocardial infarction. Circulation 118, 2057 2062 (2008).
    • (2008) Circulation , vol.118 , pp. 2057-2062
    • Velagaleti, R.S.1    Pencina, M.J.2    Murabito, J.M.3
  • 3
    • 64249107059 scopus 로고    scopus 로고
    • Evidence for cardiomyocyte renewal in humans
    • Bergmann O, Bhardwaj RD, Bernard S et al. Evidence for cardiomyocyte renewal in humans. Science 324, 98 102 (2009).
    • (2009) Science , vol.324 , pp. 98-102
    • Bergmann, O.1    Bhardwaj, R.D.2    Bernard, S.3
  • 4
    • 0037423671 scopus 로고    scopus 로고
    • Myocyte death growth and regeneration in cardiac hypertrophy and failure
    • Nadal Ginard B, Kajstura J, Leri A, Anversa P: Myocyte death, growth, and regeneration in cardiac hypertrophy and failure. Circ. Res. 92, 139 150 (2003).
    • (2003) Circ. Res. , vol.92 , pp. 139-150
    • Nadal Ginard, B.1    Kajstura, J.2    Leri, A.3    Anversa, P.4
  • 5
    • 0037112559 scopus 로고    scopus 로고
    • Derivation and potential applications of human embryonic stem cells
    • Gepstein L: Derivation and potential applications of human embryonic stem cells. Circ. Res. 91, 866 876 (2002).
    • (2002) Circ. Res. , vol.91 , pp. 866-876
    • Gepstein, L.1
  • 6
    • 39749105397 scopus 로고    scopus 로고
    • Stem cell therapy for cardiac disease
    • Segers VF, Lee RT: Stem cell therapy for cardiac disease. Nature 451, 937 942 (2008).
    • (2008) Nature , vol.451 , pp. 937-942
    • Segers, V.F.1    Lee, R.T.2
  • 7
    • 49249127331 scopus 로고    scopus 로고
    • Paracrine effects of cell transplantation: Strategies to augment the efficacy of cell therapies
    • Cheng AS, Yau TM: Paracrine effects of cell transplantation: strategies to augment the efficacy of cell therapies. Semin. Thorac. Cardiovasc. Surg. 20, 94 101 (2008).
    • (2008) Semin. Thorac Cardiovasc. Surg. , vol.20 , pp. 94-101
    • Cheng, A.S.1    Yau, T.M.2
  • 8
    • 37249084757 scopus 로고    scopus 로고
    • Prospective randomized trial of direct endomyocardial implantation of bone marrow cells for treatment of severe coronary artery diseases PROTECT CAD trial
    • Tse HF, Thambar S, Kwong YL et al. Prospective randomized trial of direct endomyocardial implantation of bone marrow cells for treatment of severe coronary artery diseases (PROTECT CAD trial). Eur. Heart J. 28, 2998 3005 (2007).
    • (2007) Eur. Heart J. , vol.28 , pp. 2998-3005
    • Tse, H.F.1    Thambar, S.2    Kwong, Y.L.3
  • 10
    • 58149347238 scopus 로고    scopus 로고
    • Paracrine mechanisms in adult stem cell signaling and therapy
    • Gnecchi M, Zhang Z, Ni A, Dzau VJ: Paracrine mechanisms in adult stem cell signaling and therapy. Circ. Res. 103, 1204 1219 (2008).
    • (2008) Circ. Res. , vol.103 , pp. 1204-1219
    • Gnecchi, M.1    Zhang, Z.2    Ni, A.3    Dzau, V.J.4
  • 12
    • 11144356049 scopus 로고    scopus 로고
    • Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts
    • Murry CE, Soonpaa MH, Reinecke H et al. Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts. Nature 428, 664 668 (2004).
    • (2004) Nature , vol.428 , pp. 664-668
    • Murry, C.E.1    Soonpaa, M.H.2    Reinecke, H.3
  • 13
    • 49149122875 scopus 로고    scopus 로고
    • Comparison of different adult stem cell types for treatment of myocardial ischemia
    • van der Bogt KE, Sheikh AY, Schrepfer S et al. Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation 118, S121 S129 (2008).
    • (2008) Circulation , vol.118
    • Van Der Bogt, K.E.1    Sheikh, A.Y.2    Schrepfer, S.3
  • 14
    • 49049115952 scopus 로고    scopus 로고
    • Paracrine effects of cell transplantation: Modifying ventricular remodeling in the failing heart
    • Fedak PW: Paracrine effects of cell transplantation: modifying ventricular remodeling in the failing heart. Semin. Thorac. Cardiovasc. Surg. 20, 87 93 (2008).
    • (2008) Semin. Thorac. Cardiovasc. Surg. , vol.20 , pp. 87-93
    • Fedak, P.W.1
  • 15
    • 67649865604 scopus 로고    scopus 로고
    • Injection of bone marrow cell extract into infarcted hearts results in functional improvement comparable to intact cell therapy
    • Yeghiazarians Y, Zhang Y, Prasad M et al. Injection of bone marrow cell extract into infarcted hearts results in functional improvement comparable to intact cell therapy. Mol. Ther. 17(7), 1250 1256 (2009).
    • (2009) Mol. Ther. , vol.17 , Issue.7 , pp. 1250-1256
    • Yeghiazarians, Y.1    Zhang, Y.2    Prasad, M.3
  • 16
    • 0037420105 scopus 로고    scopus 로고
    • Autologous skeletal myoblasts transplanted to ischemia damaged myocardium in humans Histological analysis of cell survival and differentiation
    • Pagani FD, DerSimonian H, Zawadzka A et al. Autologous skeletal myoblasts transplanted to ischemia damaged myocardium in humans. Histological analysis of cell survival and differentiation. J. Am. Coll. Cardiol. 41, 879 888 (2003).
    • (2003) J. Am. Coll. Cardiol. , vol.41 , pp. 879-888
    • Pagani, F.D.1    DerSimonian, H.2    Zawadzka, A.3
  • 17
    • 0029037189 scopus 로고
    • Cellular cardiomyoplasty: Myocardial regeneration with satellite cell implantation
    • Chiu RC, Zibaitis A, Kao RL: Cellular cardiomyoplasty: myocardial regeneration with satellite cell implantation. Ann. Thorac. Surg. 60, 12 18 (1995).
    • (1995) Ann. Thorac. Surg. , vol.60 , pp. 12-18
    • Chiu, R.C.1    Zibaitis, A.2    Kao, R.L.3
  • 18
    • 0035836582 scopus 로고    scopus 로고
    • Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction
    • Jain M, DerSimonian H, Brenner DA et al. Cell therapy attenuates deleterious ventricular remodeling and improves cardiac performance after myocardial infarction. Circulation 103, 1920 1927 (2001).
    • (2001) Circulation , vol.103 , pp. 1920-1927
    • Jain, M.1    DerSimonian, H.2    Brenner, D.A.3
  • 20
    • 0034619566 scopus 로고    scopus 로고
    • Intramyocardial transplantation of autologous myoblasts: Can tissue processing be optimized
    • III210 III215 (
    • Pouzet B, Vilquin JT, Hagege AA et al. Intramyocardial transplantation of autologous myoblasts: can tissue processing be optimized? Circulation 102, III210 III215 (2000).
    • (2000) Circulation , vol.102
    • Pouzet, B.1    Vilquin, J.T.2    Hagege, A.A.3
  • 22
    • 0034042954 scopus 로고    scopus 로고
    • Comparison of the effects of fetal cardiomyocyte and skeletal myoblast transplantation on postinfarction left ventricular function
    • Scorsin M, Hagege A, Vilquin JT et al. Comparison of the effects of fetal cardiomyocyte and skeletal myoblast transplantation on postinfarction left ventricular function. J. Thorac. Cardiovasc. Surg. 119, 1169 1175 (2000).
    • (2000) J. Thorac. Cardiovasc. Surg. , vol.119 , pp. 1169-1175
    • Scorsin, M.1    Hagege, A.2    Vilquin, J.T.3
  • 23
    • 0031928026 scopus 로고    scopus 로고
    • Regenerating functional myocardium: Improved performance after skeletal myoblast transplantation
    • Taylor DA, Atkins BZ, Hungspreugs P et al. Regenerating functional myocardium: improved performance after skeletal myoblast transplantation. Nat. Med. 4, 929 933 (1998).
    • (1998) Nat. Med. , vol.4 , pp. 929-933
    • Taylor, D.A.1    Atkins, B.Z.2    Hungspreugs, P.3
  • 24
    • 0035956699 scopus 로고    scopus 로고
    • Myoblast transplantation for heart failure
    • Menasche P, Hagege AA, Scorsin M et al. Myoblast transplantation for heart failure. Lancet 357, 279 280 (2001).
    • (2001) Lancet , vol.357 , pp. 279-0280
    • Menasche, P.1    Hagege, A.A.2    Scorsin, M.3
  • 26
    • 33645384474 scopus 로고    scopus 로고
    • Autologous skeletal myoblast transplantation in patients with nonacute myocardial infarction: 1 year follow up
    • Gavira JJ, Herreros J, Perez A et al. Autologous skeletal myoblast transplantation in patients with nonacute myocardial infarction: 1 year follow up. J. Thorac. Cardiovasc. Surg. 131, 799 804 (2006).
    • (2006) J. Thorac. Cardiovasc. Surg. , vol.131 , pp. 799-804
    • Gavira, J.J.1    Herreros, J.2    Perez, A.3
  • 27
    • 0037414086 scopus 로고    scopus 로고
    • Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction
    • Menasche P, Hagege AA, Vilquin JT et al. Autologous skeletal myoblast transplantation for severe postinfarction left ventricular dysfunction. J. Am. Coll. Cardiol. 41, 1078 1083 (2003).
    • (2003) J. Am. Coll. Cardiol. , vol.41 , pp. 1078-1083
    • Menasche, P.1    Hagege, A.A.2    Vilquin, J.T.3
  • 28
    • 0346881738 scopus 로고    scopus 로고
    • Przezsḱrny przeszczep autologicznych mioblastów w leczeniu pozawałowych zaburzeń kurczliwości mieśnia sercowego: Opis dwóch przypadków
    • Siminiak T, Fiszer D, Jerzykowska O, Grygielska B, Kalmucki P, Kurpisz M: Percutaneous autologous myoblast transplantation in the treatment of post infarction myocardial contractility impairment report on two cases. Kardiol. Pol. 59, 492 501 (2003). (Pubitemid 38017162)
    • (2003) Kardiologia Polska , vol.59 , Issue.12 , pp. 492-501
    • Siminiak, T.1    Fiszer, D.2    Jerzykowska, O.3    Grygielska, B.4    Kalmucki, P.5    Kurpisz, M.6
  • 29
    • 4644367092 scopus 로고    scopus 로고
    • Autologous skeletal myoblast transplantation for the treatment of postinfarction myocardial injury: Phase I clinical study with 12 months of follow up
    • Siminiak T, Kalawski R, Fiszer D et al. Autologous skeletal myoblast transplantation for the treatment of postinfarction myocardial injury: Phase I clinical study with 12 months of follow up. Am. Heart J. 148, 531 537 (2004).
    • (2004) Am. Heart J. , vol.148 , pp. 531-537
    • Siminiak, T.1    Kalawski, R.2    Fiszer, D.3
  • 30
    • 0035497306 scopus 로고    scopus 로고
    • Overexpression of connexin 43 in skeletal myoblasts: Relevance to cell transplantation to the heart
    • Suzuki K, Brand NJ, Allen S et al. Overexpression of connexin 43 in skeletal myoblasts: relevance to cell transplantation to the heart. J. Thorac. Cardiovasc. Surg. 122, 759 766 (2001).
    • (2001) J. Thorac. Cardiovasc. Surg. , vol.122 , pp. 759-766
    • Suzuki, K.1    Brand, N.J.2    Allen, S.3
  • 31
    • 0042917728 scopus 로고    scopus 로고
    • Comparison of intracardiac cell transplantation: Autologous skeletal myoblasts versus bone marrow cells
    • II264 II271
    • Thompson RB, Emani SM, Davis BH et al. Comparison of intracardiac cell transplantation: autologous skeletal myoblasts versus bone marrow cells. Circulation 108(Suppl. 1), II264 II271 (2003).
    • (2003) Circulation , vol.108 , Issue.1
    • Thompson, R.B.1    Emani, S.M.2    Davis, B.H.3
  • 32
    • 0035810240 scopus 로고    scopus 로고
    • Bone marrow cells regenerate infarcted myocardium
    • Orlic D, Kajstura J, Chimenti S et al. Bone marrow cells regenerate infarcted myocardium. Nature 410, 701 705 (2001).
    • (2001) Nature , vol.410 , pp. 701-705
    • Orlic, D.1    Kajstura, J.2    Chimenti, S.3
  • 33
    • 2442675144 scopus 로고    scopus 로고
    • Bone marrow derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion but not transdifferentiation
    • Nygren JM, Jovinge S, Breitbach M et al. Bone marrow derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation. Nat. Med. 10, 494 501 (2004).
    • (2004) Nat. Med. , vol.10 , pp. 494-501
    • Nygren, J.M.1    Jovinge, S.2    Breitbach, M.3
  • 34
    • 34247882004 scopus 로고    scopus 로고
    • Bone marrow stem cell therapy for myocardial angiogenesis
    • Tse HF, Yiu KH, Lau CP: Bone marrow stem cell therapy for myocardial angiogenesis. Curr. Vasc. Pharmacol. 5, 103 112 (2007).
    • (2007) Curr. Vasc. Pharmacol. , vol.5 , pp. 103-112
    • Tse, H.F.1    Yiu, K.H.2    Lau, C.P.3
  • 35
    • 38749111837 scopus 로고    scopus 로고
    • New insights on endothelial progenitor cell subpopulations and their angiogenic properties
    • Shantsila E, Watson T, Tse HF, Lip GY: New insights on endothelial progenitor cell subpopulations and their angiogenic properties. J. Am. Coll. Cardiol. 51, 669 671 (2008).
    • (2008) J. Am. Coll. Cardiol. , vol.51 , pp. 669-671
    • Shantsila, E.1    Watson, T.2    Tse, H.F.3    Lip, G.Y.4
  • 36
    • 0031019745 scopus 로고    scopus 로고
    • Isolation of putative progenitor endothelial cells for angiogenesis
    • Asahara T, Murohara T, Sullivan A et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275, 964 967 (1997).
    • (1997) Science , vol.275 , pp. 964-967
    • Asahara, T.1    Murohara, T.2    Sullivan, A.3
  • 38
    • 0032528555 scopus 로고    scopus 로고
    • Evidence for circulating bone marrow derived endothelial cells
    • Shi Q, Rafii S, Wu MH et al. Evidence for circulating bone marrow derived endothelial cells. Blood 92, 362 367 (1998).
    • (1998) Blood , vol.92 , pp. 362-367
    • Shi, Q.1    Rafii, S.2    Wu, M.H.3
  • 39
    • 0033515827 scopus 로고    scopus 로고
    • Multilineage potential of adult human mesenchymal stem cells
    • Pittenger MF, Mackay AM, Beck SC et al. Multilineage potential of adult human mesenchymal stem cells. Science 284, 143 147 (1999).
    • (1999) Science , vol.284 , pp. 143-147
    • Pittenger, M.F.1    Mackay, A.M.2    Beck, S.C.3
  • 40
    • 0033106384 scopus 로고    scopus 로고
    • Cardiomyocytes can be generated from marrow stromal cells in vitro
    • Makino S, Fukuda K, Miyoshi S et al. Cardiomyocytes can be generated from marrow stromal cells in vitro. J. Clin. Invest. 103, 697 705 (1999).
    • (1999) J. Clin. Invest. , vol.103 , pp. 697-705
    • Makino, S.1    Fukuda, K.2    Miyoshi, S.3
  • 41
    • 23844475067 scopus 로고    scopus 로고
    • Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction
    • Amado LC, Saliaris AP, Schuleri KH et al. Cardiac repair with intramyocardial injection of allogeneic mesenchymal stem cells after myocardial infarction. Proc. Natl Acad. Sci. USA 102, 11474 11479 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 11474-11479
    • Amado, L.C.1    Saliaris, A.P.2    Schuleri, K.H.3
  • 42
    • 3142663241 scopus 로고    scopus 로고
    • Mesenchymal stem cells and their potential as cardiac therapeutics
    • Pittenger MF, Martin BJ: Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res. 95, 9 20 (2004).
    • (2004) Circ. Res. , vol.95 , pp. 9-20
    • Pittenger, M.F.1    Martin, B.J.2
  • 43
    • 0037019337 scopus 로고    scopus 로고
    • Pluripotency of mesenchymal stem cells derived from adult marrow
    • Jiang Y, Jahagirdar BN, Reinhardt RL et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature 418, 41 49 (2002).
    • (2002) Nature , vol.418 , pp. 41-49
    • Jiang, Y.1    Jahagirdar, B.N.2    Reinhardt, R.L.3
  • 44
    • 20144362576 scopus 로고    scopus 로고
    • Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction
    • Yoon YS, Wecker A, Heyd L et al. Clonally expanded novel multipotent stem cells from human bone marrow regenerate myocardium after myocardial infarction. J. Clin. Invest. 115, 326 338 (2005).
    • (2005) J. Clin. Invest. , vol.115 , pp. 326-338
    • Yoon, Y.S.1    Wecker, A.2    Heyd, L.3
  • 45
    • 1042302786 scopus 로고    scopus 로고
    • Spontaneous cardiomyocyte differentiation from adipose tissue stroma cells
    • Planat Benard V, Menard C, Andre M et al. Spontaneous cardiomyocyte differentiation from adipose tissue stroma cells. Circ. Res. 94, 223 229 (2004).
    • (2004) Circ. Res. , vol.94 , pp. 223-229
    • Planat Benard, V.1    Menard, C.2    Andre, M.3
  • 46
    • 10744222119 scopus 로고    scopus 로고
    • Plasticity of human adipose lineage cells toward endothelial cells: Physiological and therapeutic perspectives
    • Planat Benard V, Silvestre JS, Cousin B et al. Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives. Circulation 109, 656 663 (2004).
    • (2004) Circulation , vol.109 , pp. 656-663
    • Planat Benard, V.1    Silvestre, J.S.2    Cousin, B.3
  • 47
    • 33645740062 scopus 로고    scopus 로고
    • Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction
    • Miyahara Y, Nagaya N, Kataoka M et al. Monolayered mesenchymal stem cells repair scarred myocardium after myocardial infarction. Nat. Med. 12, 459 465 (2006).
    • (2006) Nat. Med. , vol.12 , pp. 459-465
    • Miyahara, Y.1    Nagaya, N.2    Kataoka, M.3
  • 48
    • 34248332602 scopus 로고    scopus 로고
    • Adipose derived stem cells for regenerative medicine
    • Gimble JM, Katz AJ, Bunnell BA: Adipose derived stem cells for regenerative medicine. Circ. Res. 100, 1249 1260 (2007).
    • (2007) Circ. Res. , vol.100 , pp. 1249-1260
    • Gimble, J.M.1    Katz, A.J.2    Bunnell, B.A.3
  • 49
    • 67449087553 scopus 로고    scopus 로고
    • Ex vivo nanofiber expansion and genetic modification of human cord blood derived progenitor/stem cells enhances vasculogenesis
    • Das H, Abdulhameed N, Joseph M, Sakthivel R, Mao HQ, Pompili VJ: Ex vivo nanofiber expansion and genetic modification of human cord blood derived progenitor/stem cells enhances vasculogenesis. Cell Transplant. 18, 305 318 (2009).
    • (2009) Cell Transplant. , vol.18 , pp. 305-318
    • Das, H.1    Abdulhameed, N.2    Joseph, M.3    Sakthivel, R.4    Mao, H.Q.5    Pompili, V.J.6
  • 50
    • 20144380166 scopus 로고    scopus 로고
    • Human cord blood cells induce angiogenesis following myocardial infarction in NOD/scid mice
    • Ma N, Stamm C, Kaminski A et al. Human cord blood cells induce angiogenesis following myocardial infarction in NOD/scid mice. Cardiovasc. Res. 66, 45 54 (2005).
    • (2005) Cardiovasc. Res , vol.66 , pp. 45-54
    • Ma, N.1    Stamm, C.2    Kaminski, A.3
  • 51
    • 58349097296 scopus 로고    scopus 로고
    • Transplanted human cord blood derived unrestricted somatic stem cells improve left ventricular function and prevent left ventricular dilation and scar formation after acute myocardial infarction
    • Ghodsizad A, Niehaus M, Kogler G et al. Transplanted human cord blood derived unrestricted somatic stem cells improve left ventricular function and prevent left ventricular dilation and scar formation after acute myocardial infarction. Heart 95, 27 35 (2009).
    • (2009) Heart , vol.95 , pp. 27-35
    • Ghodsizad, A.1    Niehaus, M.2    Kogler, G.3
  • 52
    • 10744228523 scopus 로고    scopus 로고
    • Adult cardiac stem cells are multipotent and support myocardial regeneration
    • Beltrami AP, Barlucchi L, Torella D et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114, 763 776 (2003).
    • (2003) Cell , vol.114 , pp. 763-776
    • Beltrami, A.P.1    Barlucchi, L.2    Torella, D.3
  • 54
    • 63049114516 scopus 로고    scopus 로고
    • Imaging survival and function of transplanted cardiac resident stem cells
    • Li Z, Lee A, Huang M et al. Imaging survival and function of transplanted cardiac resident stem cells. J. Am. Coll. Cardiol. 53, 1229 1240 (2009).
    • (2009) J. Am. Coll. Cardiol. , vol.53 , pp. 1229-1240
    • Li, Z.1    Lee, A.2    Huang, M.3
  • 55
    • 33847145871 scopus 로고    scopus 로고
    • Regenerative potential of cardiosphere derived cells expanded from percutaneous endomyocardial biopsy specimens
    • Smith RR, Barile L, Cho HC et al. Regenerative potential of cardiosphere derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 115, 896 908 (2007).
    • (2007) Circulation , vol.115 , pp. 896-908
    • Smith, R.R.1    Barile, L.2    Cho, H.C.3
  • 56
    • 68049123595 scopus 로고    scopus 로고
    • Murine cardiospheres are not a source of stem cells with cardiomyogenic potential
    • Andersen DC, Andersen P, Schneider M, Jensen HB, Sheikh SP: Murine cardiospheres are not a source of stem cells with cardiomyogenic potential. Stem Cells 27, 1571 1581 (2009).
    • (2009) Stem Cells , vol.27 , pp. 1571-1581
    • Andersen, D.C.1    Andersen, P.2    Schneider, M.3    Jensen, H.B.4    Sheikh, S.P.5
  • 57
    • 0034983625 scopus 로고    scopus 로고
    • Multilineage differentiation from human embryonic stem cell lines
    • Odorico JS, Kaufman DS, Thomson JA: Multilineage differentiation from human embryonic stem cell lines. Stem Cells 19, 193 204 (2001).
    • (2001) Stem Cells , vol.19 , pp. 193-204
    • Odorico, J.S.1    Kaufman, D.S.2    Thomson, J.A.3
  • 58
    • 0034101804 scopus 로고    scopus 로고
    • Embryonic stem cell lines from human blastocysts: Somatic differentiation in vitro
    • Reubinoff BE, Pera MF, Fong CY, Trounson A, Bongso A: Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro. Nat. Biotechnol. 18, 399 404 (2000).
    • (2000) Nat. Biotechnol. , vol.18 , pp. 399-404
    • Reubinoff, B.E.1    Pera, M.F.2    Fong, C.Y.3    Trounson, A.4    Bongso, A.5
  • 59
    • 0034904645 scopus 로고    scopus 로고
    • Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes
    • Kehat I, Kenyagin Karsenti D, Snir M et al. Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J. Clin. Invest. 108, 407 414 (2001).
    • (2001) J. Clin. Invest. , vol.108 , pp. 407-414
    • Kehat, I.1    Kenyagin Karsenti, D.2    Snir, M.3
  • 60
    • 0038300672 scopus 로고    scopus 로고
    • Human embryonic stem cells develop into multiple types of cardiac myocytes: Action potential characterization
    • He JQ, Ma Y, Lee Y, Thomson JA, Kamp TJ: Human embryonic stem cells develop into multiple types of cardiac myocytes: action potential characterization. Circ. Res. 93, 32 39 (2003).
    • (2003) Circ. Res. , vol.93 , pp. 32-39
    • He, J.Q.1    Ma, Y.2    Lee, Y.3    Thomson, J.A.4    Kamp, T.J.5
  • 61
    • 54249093380 scopus 로고    scopus 로고
    • Human embryonic stem cells for cardiomyogenesis
    • Habib M, Caspi O, Gepstein L: Human embryonic stem cells for cardiomyogenesis. J. Mol. Cell. Cardiol. 45, 462 474 (2008).
    • (2008) J. Mol. Cell. Cardiol. , vol.45 , pp. 462-474
    • Habib, M.1    Caspi, O.2    Gepstein, L.3
  • 62
    • 65349084436 scopus 로고    scopus 로고
    • Stem cell therapy is proarrhythmic
    • Macia E, Boyden PA: Stem cell therapy is proarrhythmic. Circulation 119, 1814 1823 (2009).
    • (2009) Circulation , vol.119 , pp. 1814-1823
    • Macia, E.1    Boyden, P.A.2
  • 64
    • 37549001280 scopus 로고    scopus 로고
    • Human embryonic stem cells are prone to generate primitive undifferentiated tumors in engrafted human fetal tissues in severe combined immunodeficient mice
    • Shih CC, Forman SJ, Chu P, Slovak M: Human embryonic stem cells are prone to generate primitive, undifferentiated tumors in engrafted human fetal tissues in severe combined immunodeficient mice. Stem Cells Dev. 16, 893 902 (2007).
    • (2007) Stem Cells Dev. , vol.16 , pp. 893-902
    • Shih, C.C.1    Forman, S.J.2    Chu, P.3    Slovak, M.4
  • 65
    • 37549067673 scopus 로고    scopus 로고
    • Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation
    • Cao F, van der Bogt KE, Sadrzadeh A et al. Spatial and temporal kinetics of teratoma formation from murine embryonic stem cell transplantation. Stem Cells Dev. 16, 883 891 (2007).
    • (2007) Stem Cells Dev. , vol.16 , pp. 883-891
    • Cao, F.1    Van Der Bogt, K.E.2    Sadrzadeh, A.3
  • 66
    • 38049187707 scopus 로고    scopus 로고
    • Reprogramming of human somatic cells to pluripotency with defined factors
    • Park IH, Zhao R, West JA et al. Reprogramming of human somatic cells to pluripotency with defined factors. Nature 451, 141 146 (2008).
    • (2008) Nature , vol.451 , pp. 141-146
    • Park, I.H.1    Zhao, R.2    West, J.A.3
  • 67
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861 872 (2007).
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 68
    • 36749043230 scopus 로고    scopus 로고
    • Induced pluripotent stem cell lines derived from human somatic cells
    • Yu J, Vodyanik MA, Smuga Otto K et al. Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917 1920 (2007).
    • (2007) Science , vol.318 , pp. 1917-1920
    • Yu, J.1    Vodyanik, M.A.2    Smuga Otto, K.3
  • 69
    • 49649096192 scopus 로고    scopus 로고
    • Generation of functional murine cardiac myocytes from induced pluripotent stem cells
    • Mauritz C, Schwanke K, Reppel M et al. Generation of functional murine cardiac myocytes from induced pluripotent stem cells. Circulation 118, 507 517 (2008).
    • (2008) Circulation , vol.118 , pp. 507-517
    • Mauritz, C.1    Schwanke, K.2    Reppel, M.3
  • 70
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline competent induced pluripotent stem cells
    • Okita K, Ichisaka T, Yamanaka S: Generation of germline competent induced pluripotent stem cells. Nature 448, 313 317 (2007).
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 71
    • 55849117368 scopus 로고    scopus 로고
    • Generation of mouse induced pluripotent stem cells without viral vectors
    • Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S: Generation of mouse induced pluripotent stem cells without viral vectors. Science 322, 949 953 (2008).
    • (2008) Science , vol.322 , pp. 949-953
    • Okita, K.1    Nakagawa, M.2    Hyenjong, H.3    Ichisaka, T.4    Yamanaka, S.5
  • 72
    • 55849115999 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated without viral integration
    • Stadtfeld M, Nagaya M, Utikal J, Weir G, Hochedlinger K: Induced pluripotent stem cells generated without viral integration. Science 322, 945 949 (2008).
    • (2008) Science , vol.322 , pp. 945-949
    • Stadtfeld, M.1    Nagaya, M.2    Utikal, J.3    Weir, G.4    Hochedlinger, K.5
  • 73
    • 65449154892 scopus 로고    scopus 로고
    • Generation of transgene free induced pluripotent mouse stem cells by the piggybac transposon
    • Yusa K, Rad R, Takeda J, Bradley A: Generation of transgene free induced pluripotent mouse stem cells by the piggyBac transposon. Nat. Methods 6, 363 369 (2009).
    • (2009) Nat. Methods , vol.6 , pp. 363-369
    • Yusa, K.1    Rad, R.2    Takeda, J.3    Bradley, A.4
  • 74
    • 64749083939 scopus 로고    scopus 로고
    • PiggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
    • Woltjen K, Michael IP, Mohseni P et al. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766 770 (2009).
    • (2009) Nature , vol.458 , pp. 766-770
    • Woltjen, K.1    Michael, I.P.2    Mohseni, P.3
  • 75
    • 64749111225 scopus 로고    scopus 로고
    • Virus free induction of pluripotency and subsequent excision of reprogramming factors
    • Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K: Virus free induction of pluripotency and subsequent excision of reprogramming factors. Nature 458, 771 775 (2009).
    • (2009) Nature , vol.458 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3    Mileikovsky, M.4    Mohseni, P.5    Woltjen, K.6
  • 76
    • 61349100729 scopus 로고    scopus 로고
    • Parkinson's disease patient derived induced pluripotent stem cells free of viral reprogramming factors
    • Soldner F, Hockemeyer D, Beard C et al. Parkinson's disease patient derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136, 964 977 (2009).
    • (2009) Cell , vol.136 , pp. 964-977
    • Soldner, F.1    Hockemeyer, D.2    Beard, C.3
  • 77
    • 66049143859 scopus 로고    scopus 로고
    • Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
    • Kim D, Kim CH, Moon JI et al. Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4, 472 476 (2009).
    • (2009) Cell Stem Cell , vol.4 , pp. 472-476
    • Kim, D.1    Kim, C.H.2    Moon, J.I.3
  • 78
    • 45149116677 scopus 로고    scopus 로고
    • The stem cell movement
    • Smart N, Riley PR: The stem cell movement. Circ. Res. 102, 1155 1168 (2008).
    • (2008) Circ. Res. , vol.102 , pp. 1155-1168
    • Smart, N.1    Riley, P.R.2
  • 80
    • 33947305414 scopus 로고    scopus 로고
    • Adult bone marrow derived cells for cardiac repair: A systematic review and meta analysis
    • Abdel Latif A, Bolli R, Tleyjeh IM et al. Adult bone marrow derived cells for cardiac repair: a systematic review and meta analysis. Arch. Intern. Med. 167, 989 997 (2007).
    • (2007) Arch. Intern. Med. , vol.167 , pp. 989-997
    • Abdel Latif, A.1    Bolli, R.2    Tleyjeh, I.M.3
  • 81
    • 35349008966 scopus 로고    scopus 로고
    • Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: A collaborative systematic review and meta analysis of controlled clinical trials
    • Lipinski MJ, Biondi Zoccai GG, Abbate A et al. Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta analysis of controlled clinical trials. J. Am. Coll. Cardiol. 50, 1761 1767 (2007).
    • (2007) J. Am. Coll. Cardiol. , vol.50 , pp. 1761-1767
    • Lipinski, M.J.1    Biondi Zoccai, G.G.2    Abbate, A.3
  • 82
    • 40349110711 scopus 로고    scopus 로고
    • Clinical applications of blood derived and marrow derived stem cells for nonmalignant diseases
    • Burt RK, Loh Y, Pearce W et al. Clinical applications of blood derived and marrow derived stem cells for nonmalignant diseases. JAMA 299, 925 936 (2008).
    • (2008) JAMA , vol.299 , pp. 925-936
    • Burt, R.K.1    Loh, Y.2    Pearce, W.3
  • 83
    • 33748910402 scopus 로고    scopus 로고
    • Intracoronary bone marrow derived progenitor cells in acute myocardial infarction
    • Schachinger V, Erbs S, Elsasser A et al. Intracoronary bone marrow derived progenitor cells in acute myocardial infarction. N. Engl. J. Med. 355, 1210 1221 (2006).
    • (2006) N. Engl. J. Med. , vol.355 , pp. 1210-1221
    • Schachinger, V.1    Erbs, S.2    Elsasser, A.3
  • 84
    • 64949137802 scopus 로고    scopus 로고
    • Cell therapy success does not come easy
    • Tendera M, Wojakowski W: Cell therapy success does not come easy. Eur. Heart J. 30, 640 641 (2009).
    • (2009) Eur. Heart J. , vol.30 , pp. 640-641
    • Tendera, M.1    Wojakowski, W.2
  • 85
    • 58249087047 scopus 로고    scopus 로고
    • Promise of blood and bone marrow derived stem cell transplantation for functional cardiac repair: Putting it in perspective with existing therapy
    • Reffelmann T, Konemann S, Kloner RA: Promise of blood and bone marrow derived stem cell transplantation for functional cardiac repair: putting it in perspective with existing therapy. J. Am. Coll. Cardiol. 53, 305 308 (2009).
    • (2009) J. Am. Coll. Cardiol. , vol.53 , pp. 305-308
    • Reffelmann, T.1    Konemann, S.2    Kloner, R.A.3
  • 86
    • 34347402502 scopus 로고    scopus 로고
    • Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: A phase I/IIa double blind, randomized controlled trial
    • Losordo DW, Schatz RA, White CJ et al. Intramyocardial transplantation of autologous CD34+ stem cells for intractable angina: a phase I/IIa double blind, randomized controlled trial. Circulation 115, 3165 3172 (2007).
    • (2007) Circulation , vol.115 , pp. 3165-3172
    • Losordo, D.W.1    Schatz, R.A.2    White, C.J.3
  • 87
    • 65649129319 scopus 로고    scopus 로고
    • Intramyocardial bone marrow cell injection for chronic myocardial ischemia: A randomized controlled trial
    • van Ramshorst J, Bax JJ, Beeres SL et al. Intramyocardial bone marrow cell injection for chronic myocardial ischemia: a randomized controlled trial. JAMA 301, 1997 2004 (2009).
    • (2009) JAMA , vol.301 , pp. 1997-2004
    • Van Ramshorst, J.1    Bax, J.J.2    Beeres, S.L.3
  • 88
    • 41149106402 scopus 로고    scopus 로고
    • The myoblast autologous grafting in ischemic cardiomyopathy magic trial: First randomized placebo controlled study of myoblast transplantation
    • Menasche P, Alfieri O, Janssens S et al. The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo controlled study of myoblast transplantation. Circulation 117, 1189 1200 (2008).
    • (2008) Circulation , vol.117 , pp. 1189-1200
    • Menasche, P.1    Alfieri, O.2    Janssens, S.3
  • 89
    • 33746930399 scopus 로고    scopus 로고
    • Skeletal myoblast transplantation in ischemic heart failure: Long term follow up of the first Phase I cohort of patients
    • Hagege AA, Marolleau JP, Vilquin JT et al. Skeletal myoblast transplantation in ischemic heart failure: long term follow up of the first Phase I cohort of patients. Circulation 114, I108 I113 (2006).
    • (2006) Circulation , vol.114
    • Hagege, A.A.1    Marolleau, J.P.2    Vilquin, J.T.3
  • 90
    • 33847099628 scopus 로고    scopus 로고
    • If I can stop one heart from breaking
    • Anversa P, Kajstura J, Leri A: If I can stop one heart from breaking. Circulation 115, 829 832 (2007).
    • (2007) Circulation , vol.115 , pp. 829-832
    • Anversa, P.1    Kajstura, J.2    Leri, A.3
  • 91
    • 20544450374 scopus 로고    scopus 로고
    • Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction
    • discussion 236-237
    • Tang YL, Zhao Q, Qin X et al. Paracrine action enhances the effects of autologous mesenchymal stem cell transplantation on vascular regeneration in rat model of myocardial infarction. Ann. Thorac. Surg. 80, 229 236; discussion 236 237 (2005).
    • (2005) Ann. Thorac. Surg. , vol.80 , pp. 229-236
    • Tang, Y.L.1    Zhao, Q.2    Qin, X.3
  • 92
    • 34447309095 scopus 로고    scopus 로고
    • Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: Restoration by the peroxisome proliferator activated receptor g agonist rosiglitazone
    • Sorrentino SA, Bahlmann FH, Besler C et al. Oxidant stress impairs in vivo reendothelialization capacity of endothelial progenitor cells from patients with Type 2 diabetes mellitus: restoration by the peroxisome proliferator activated receptor g agonist rosiglitazone. Circulation 116, 163 173 (2007).
    • (2007) Circulation , vol.116 , pp. 163-173
    • Sorrentino, S.A.1    Bahlmann, F.H.2    Besler, C.3
  • 93
    • 34249995713 scopus 로고    scopus 로고
    • Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure
    • Kissel CK, Lehmann R, Assmus B et al. Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure. J. Am. Coll. Cardiol. 49, 2341 2349 (2007).
    • (2007) J. Am. Coll. Cardiol. , vol.49 , pp. 2341-2349
    • Kissel, C.K.1    Lehmann, R.2    Assmus, B.3
  • 94
    • 33947310406 scopus 로고    scopus 로고
    • Cell isolation procedures matter: A comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction
    • Seeger FH, Tonn T, Krzossok N, Zeiher AM, Dimmeler S: Cell isolation procedures matter: a comparison of different isolation protocols of bone marrow mononuclear cells used for cell therapy in patients with acute myocardial infarction. Eur. Heart J. 28, 766 772 (2007).
    • (2007) Eur. Heart J. , vol.28 , pp. 766-772
    • Seeger, F.H.1    Tonn, T.2    Krzossok, N.3    Zeiher, A.M.4    Dimmeler, S.5
  • 95
    • 57349172661 scopus 로고    scopus 로고
    • Bone marrow cells are a rich source of growth factors and cytokines: Implications for cell therapy trials after myocardial infarction
    • Korf Klingebiel M, Kempf T, Sauer T et al. Bone marrow cells are a rich source of growth factors and cytokines: implications for cell therapy trials after myocardial infarction. Eur. Heart J. 29, 2851 2858 (2008).
    • (2008) Eur. Heart J. , vol.29 , pp. 2851-2858
    • Korf Klingebiel, M.1    Kempf, T.2    Sauer, T.3
  • 96
    • 33749239638 scopus 로고    scopus 로고
    • Ex vivo pretreatment of bone marrow mononuclear cells with endothelial no synthase enhancer AVE9488 enhances their functional activity for cell therapy
    • USA
    • Sasaki K, Heeschen C, Aicher A et al. Ex vivo pretreatment of bone marrow mononuclear cells with endothelial NO synthase enhancer AVE9488 enhances their functional activity for cell therapy. Proc. Natl Acad. Sci. USA 103, 14537 14541 (2006).
    • (2006) Proc. Natl. Acad. Sci. , vol.103 , pp. 14537-14541
    • Sasaki, K.1    Heeschen, C.2    Aicher, A.3
  • 97
    • 34247096395 scopus 로고    scopus 로고
    • Bioenergetic and functional consequences of bone marrow derived multipotent progenitor cell transplantation in hearts with postinfarction left ventricular remodeling
    • Zeng L, Hu Q, Wang X et al. Bioenergetic and functional consequences of bone marrow derived multipotent progenitor cell transplantation in hearts with postinfarction left ventricular remodeling. Circulation 115, 1866 1875 (2007).
    • (2007) Circulation , vol.115 , pp. 1866-1875
    • Zeng, L.1    Hu, Q.2    Wang, X.3
  • 98
    • 34047130642 scopus 로고    scopus 로고
    • Ex vivo delivered stromal cell derived factor 1a promotes stem cell homing and induces angiomyogenesis in the infarcted myocardium
    • Elmadbouh I, Haider H, Jiang S, Idris NM, Lu G, Ashraf M: Ex vivo delivered stromal cell derived factor 1a promotes stem cell homing and induces angiomyogenesis in the infarcted myocardium. J. Mol. Cell. Cardiol. 42, 792 803 (2007).
    • (2007) J. Mol. Cell. Cardiol. , vol.42 , pp. 792-803
    • Elmadbouh, I.1    Haider, H.2    Jiang, S.3    Idris, N.M.4    Lu, G.5    Ashraf, M.6
  • 99
    • 14944371450 scopus 로고    scopus 로고
    • Endothelial progenitor cells are rapidly recruited to myocardium and mediate protective effect of ischemic preconditioning via imported nitric oxide synthase activity
    • Ii M, Nishimura H, Iwakura A et al. Endothelial progenitor cells are rapidly recruited to myocardium and mediate protective effect of ischemic preconditioning via 'imported' nitric oxide synthase activity. Circulation 111, 1114 1120 (2005).
    • (2005) Circulation , vol.111 , pp. 1114-1120
    • Ii, M.1    Nishimura, H.2    Iwakura, A.3
  • 100
    • 38849108084 scopus 로고    scopus 로고
    • Stable therapeutic effects of mesenchymal stem cell based multiple gene delivery for cardiac repair
    • Shujia J, Haider HK, Idris NM, Lu G, Ashraf M: Stable therapeutic effects of mesenchymal stem cell based multiple gene delivery for cardiac repair. Cardiovasc. Res. 77, 525 533 (2008).
    • (2008) Cardiovasc. Res. , vol.77 , pp. 525-533
    • Shujia, J.1    Haider, H.K.2    Idris, N.M.3    Lu, G.4    Ashraf, M.5
  • 101
    • 36949035990 scopus 로고    scopus 로고
    • Engraftment of connexin 43 expressing cells prevents post infarct arrhythmia
    • Roell W, Lewalter T, Sasse P et al. Engraftment of connexin 43 expressing cells prevents post infarct arrhythmia. Nature 450, 819 824 (2007).
    • (2007) Nature , vol.450 , pp. 819-824
    • Roell, W.1    Lewalter, T.2    Sasse, P.3
  • 102
    • 27144526686 scopus 로고    scopus 로고
    • In search of the best candidate for regeneration of ischemic tissues: Are embryonic/fetal stem cells more advantageous than adult counterparts
    • Emanueli C, Lako M, Stojkovic M, Madeddu P: In search of the best candidate for regeneration of ischemic tissues: are embryonic/fetal stem cells more advantageous than adult counterparts? Thromb. Haemost. 94, 738 749 (2005).
    • (2005) Thromb. Haemost. , vol.94 , pp. 738-749
    • Emanueli, C.1    Lako, M.2    Stojkovic, M.3    Madeddu, P.4
  • 103
    • 0030016231 scopus 로고    scopus 로고
    • Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts
    • Klug MG, Soonpaa MH, Koh GY, Field LJ: Genetically selected cardiomyocytes from differentiating embronic stem cells form stable intracardiac grafts. J. Clin. Invest. 98, 216 224 (1996).
    • (1996) J. Clin. Invest. , vol.98 , pp. 216-224
    • Klug, M.G.1    Soonpaa, M.H.2    Koh, G.Y.3    Field, L.J.4
  • 104
    • 0036092735 scopus 로고    scopus 로고
    • Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats
    • Min JY, Yang Y, Converso KL et al. Transplantation of embryonic stem cells improves cardiac function in postinfarcted rats. J. Appl. Physiol. 92, 288 296 (2002).
    • (2002) J. Appl. Physiol. , vol.92 , pp. 288-296
    • Min, J.Y.1    Yang, Y.2    Converso, K.L.3
  • 105
    • 0036793540 scopus 로고    scopus 로고
    • Stem cell differentiation requires a paracrine pathway in the heart
    • Behfar A, Zingman LV, Hodgson DM et al. Stem cell differentiation requires a paracrine pathway in the heart. FASEB J. 16, 1558 1566 (2002).
    • (2002) FASEB J. , vol.16 , pp. 1558-1566
    • Behfar, A.1    Zingman, L.V.2    Hodgson, D.M.3
  • 106
    • 0036707851 scopus 로고    scopus 로고
    • VEGF enhances functional improvement of postinfarcted hearts by transplantation of ESC differentiated cells
    • Yang Y, Min JY, Rana JS et al. VEGF enhances functional improvement of postinfarcted hearts by transplantation of ESC differentiated cells. J. Appl. Physiol. 93, 1140 1151 (2002).
    • (2002) J. Appl. Physiol. , vol.93 , pp. 1140-1151
    • Yang, Y.1    Min, J.Y.2    Rana, J.S.3
  • 107
    • 0037326459 scopus 로고    scopus 로고
    • Long term improvement of cardiac function in rats after infarction by transplantation of embryonic stem cells
    • Min JY, Yang Y, Sullivan MF et al. Long term improvement of cardiac function in rats after infarction by transplantation of embryonic stem cells. J. Thorac. Cardiovasc. Surg. 125, 361 369 (2003).
    • (2003) J. Thorac. Cardiovasc. Surg. , vol.125 , pp. 361-369
    • Min, J.Y.1    Yang, Y.2    Sullivan, M.F.3
  • 110
    • 7544241273 scopus 로고    scopus 로고
    • In vivo MRI of embryonic stem cells in a mouse model of myocardial infarction
    • Himes N, Min JY, Lee R et al. In vivo MRI of embryonic stem cells in a mouse model of myocardial infarction. Magn. Reson. Med. 52, 1214 1219 (2004).
    • (2004) Magn. Reson. Med. , vol.52 , pp. 1214-1219
    • Himes, N.1    Min, J.Y.2    Lee, R.3
  • 111
    • 4644356795 scopus 로고    scopus 로고
    • Injectable bioartificial myocardial tissue for large scale intramural cell transfer and functional recovery of injured heart muscle
    • Kofidis T, de Bruin JL, Hoyt G et al. Injectable bioartificial myocardial tissue for large scale intramural cell transfer and functional recovery of injured heart muscle. J. Thorac. Cardiovasc. Surg. 128, 571 578 (2004).
    • (2004) J. Thorac. Cardiovasc. Surg. , vol.128 , pp. 571-578
    • Kofidis, T.1    De Bruin, J.L.2    Hoyt, G.3
  • 112
    • 10444259877 scopus 로고    scopus 로고
    • Insulin like growth factor promotes engraftment differentiation and functional improvement after transfer of embryonic stem cells for myocardial restoration
    • Kofidis T, de Bruin JL, Yamane T et al. Insulin like growth factor promotes engraftment, differentiation, and functional improvement after transfer of embryonic stem cells for myocardial restoration. Stem Cells 22, 1239 1245 (2004).
    • (2004) Stem Cells , vol.22 , pp. 1239-1245
    • Kofidis, T.1    De Bruin, J.L.2    Yamane, T.3
  • 113
    • 9244242548 scopus 로고    scopus 로고
    • Xenogeneic embryonic stem cell derived cardiomyocyte transplantation
    • Naito H, Nishizaki K, Yoshikawa M et al. Xenogeneic embryonic stem cell derived cardiomyocyte transplantation. Transplant. Proc. 36, 2507 2508 (2004).
    • (2004) Transplant. Proc. , vol.36 , pp. 2507-2508
    • Naito, H.1    Nishizaki, K.2    Yoshikawa, M.3
  • 114
    • 24044551612 scopus 로고    scopus 로고
    • Formation of human myocardium in the rat heart from human embryonic stem cells
    • Laflamme MA, Gold J, Xu C et al. Formation of human myocardium in the rat heart from human embryonic stem cells. Am. J. Pathol. 167, 663 671 (2005).
    • (2005) Am. J. Pathol. , vol.167 , pp. 663-671
    • Laflamme, M.A.1    Gold, J.2    Xu, C.3
  • 115
    • 34247870540 scopus 로고    scopus 로고
    • Embryonic stem cells cultured in biodegradable scaffold repair infarcted myocardium in mice
    • Ke Q, Yang Y, Rana JS, Chen Y, Morgan JP, Xiao YF: Embryonic stem cells cultured in biodegradable scaffold repair infarcted myocardium in mice. Sheng Li Xue Bao 57, 673 681 (2005).
    • (2005) Sheng Li Xue Bao , vol.57 , pp. 673-681
    • Ke, Q.1    Yang, Y.2    Rana, J.S.3    Chen, Y.4    Morgan, J.P.5    Xiao, Y.F.6
  • 116
    • 24944499607 scopus 로고    scopus 로고
    • Transplantation of cardiac committed mouse embryonic stem cells to infarcted sheep myocardium: A preclinical study
    • Menard C, Hagege AA, Agbulut O et al. Transplantation of cardiac committed mouse embryonic stem cells to infarcted sheep myocardium: a preclinical study. Lancet 366, 1005 1012 (2005).
    • (2005) Lancet , vol.366 , pp. 1005-1012
    • Menard, C.1    Hagege, A.A.2    Agbulut, O.3
  • 117
    • 24644519816 scopus 로고    scopus 로고
    • Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium
    • Swijnenburg RJ, Tanaka M, Vogel H et al. Embryonic stem cell immunogenicity increases upon differentiation after transplantation into ischemic myocardium. Circulation 112, I166 I172 (2005).
    • (2005) Circulation , vol.112
    • Swijnenburg, R.J.1    Tanaka, M.2    Vogel, H.3
  • 118
    • 11244249952 scopus 로고    scopus 로고
    • Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: Insights into the development of cell based pacemakers
    • Xue T, Cho HC, Akar FG et al. Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell based pacemakers. Circulation 111, 11 20 (2005).
    • (2005) Circulation , vol.111 , pp. 11-20
    • Xue, T.1    Cho, H.C.2    Akar, F.G.3
  • 119
    • 29444434297 scopus 로고    scopus 로고
    • Transplantation of embryonic stem cells into the infarcted mouse heart: Formation of multiple cell types
    • Singla DK, Hacker TA, Ma L et al. Transplantation of embryonic stem cells into the infarcted mouse heart: formation of multiple cell types. J. Mol. Cell. Cardiol. 40, 195 200 (2006).
    • (2006) J. Mol. Cell. Cardiol. , vol.40 , pp. 195-200
    • Singla, D.K.1    Hacker, T.A.2    Ma, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.