Imaging Survival and Function of Transplanted Cardiac Resident Stem Cells

Journal of the American College of Cardiology

Volumn 53, Issue 14, 2009, Pages 1229-1240

  Li, Zongjin ^a   Lee, Andrew ^a   Huang, Mei ^a   Chun, Hyung ^a   Chung, Jaehoon ^a   Chu, Pauline ^a   Hoyt, Grant ^a   Yang, Phillip ^a   Rosenberg, Jarrett ^a   Robbins, Robert C ^a   Wu, Joseph C ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cardiac stem cells; cell fate; differentiation; ischemic heart disease; molecular imaging

Indexed keywords

ATAXIN 1; ENHANCED GREEN FLUORESCENT PROTEIN; FIREFLY LUCIFERASE; FLUORODEOXYGLUCOSE F 18; PHOSPHATE BUFFERED SALINE; STEM CELL FACTOR; THY 1 ANTIGEN; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY LIGATION; ARTICLE; AUTOPSY; BIOLUMINESCENCE; CELL FUNCTION; CELL ISOLATION; CELL SURVIVAL; CELL TRANSPLANTATION; CONTROL GROUP; CONTROLLED STUDY; DONOR; ECHOCARDIOGRAPHY; ENGRAFTMENT; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HEART; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEMODYNAMICS; HOST; IMMUNOHISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; INJECTION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MESENCHYMAL STEM CELL; MOLECULAR IMAGING; MOUSE; MOUSE STRAIN; NON INVASIVE PROCEDURE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRESSURE VOLUME CURVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPORTER GENE; STEM CELL; THERAPY EFFECT; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; DISEASE MODELS, ANIMAL; MICE; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 63049114516     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2008.12.036     Document Type: Article

References (45)

1. Rosenzweig A. Cardiac cell therapy-mixed results from mixed cells. N Engl J Med 355 (2006) 1274-1277
2. Assmus B., Honold J., Schachinger V., et al. Transcoronary transplantation of progenitor cells after myocardial infarction. N Engl J Med 355 (2006) 1222-1232
3. Wollert K.C., Meyer G.P., Lotz J., et al. Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 364 (2004) 141-148
4. Cao F., Lin S., Xie X., et al. In vivo visualization of embryonic stem cell survival, proliferation, and migration after cardiac delivery. Circulation 113 (2006) 1005-1014
5. Menasche P., Alfieri O., Janssens S., et al. The Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation. Circulation 117 (2008) 1189-1200
6. Balsam L.B., Wagers A.J., Christensen J.L., Kofidis T., Weissman I.L., and Robbins R.C. Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium. Nature 428 (2004) 668-673
7. Orlic D., Kajstura J., Chimenti S., et al. Bone marrow cells regenerate infarcted myocardium. Nature 410 (2001) 701-705
8. Beltrami A.P., Barlucchi L., Torella D., et al. Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114 (2003) 763-776
9. Dawn B., Stein A.B., Urbanek K., et al. Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function. Proc Natl Acad Sci U S A 102 (2005) 3766-3771
10. Messina E., De Angelis L., Frati G., et al. Isolation and expansion of adult cardiac stem cells from human and murine heart. Circ Res 95 (2004) 911-921
11. Oh H., Bradfute S.B., Gallardo T.D., et al. Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A 100 (2003) 12313-12318
12. Smith R.R., Barile L., Cho H.C., et al. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens. Circulation 115 (2007) 896-908
13. van der Bogt K.E., Sheikh A.Y., Schrepfer S., et al. Comparison of different adult stem cell types for treatment of myocardial ischemia. Circulation 118 (2008) S121-S129
14. Sheikh A.Y., Lin S.A., Cao F., et al. Molecular imaging of bone marrow mononuclear cell homing and engraftment in ischemic myocardium. Stem Cells 25 (2007) 2677-2684
15. Gonzalez A., Rota M., Nurzynska D., et al. Activation of cardiac progenitor cells reverses the failing heart senescent phenotype and prolongs lifespan. Circ Res 102 (2008) 597-606
16. Ott H.C., Matthiesen T.S., Brechtken J., et al. The adult human heart as a source for stem cells: repair strategies with embryonic-like progenitor cells. Nat Clin Pract Cardiovasc Med 4 (2007) Suppl 1:S27-39
17. Cao Y.A., Wagers A.J., Beilhack A., et al. Shifting foci of hematopoiesis during reconstitution from single stem cells. Proc Natl Acad Sci U S A 101 (2004) 221-226
18. Sun S., Guo Z., Xiao X., et al. Isolation of mouse marrow mesenchymal progenitors by a novel and reliable method. Stem Cells 21 (2003) 527-535
19. Li Z., Wu J.C., Sheikh A.Y., et al. Differentiation, survival, and function of embryonic stem cell derived endothelial cells for ischemic heart disease. Circulation 116 (2007) I46-I54
20. Li Z.J., Wang Z.Z., Zheng Y.Z., et al. Kinetic expression of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) during embryonic stem cell differentiation. J Cell Biochem 95 (2005) 559-570
21. Matsuura K., Nagai T., Nishigaki N., et al. Adult cardiac Sca-1-positive cells differentiate into beating cardiomyocytes. J Biol Chem 279 (2004) 11384-11391
22. Toyama H., Ichise M., Liow J.S., et al. Evaluation of anesthesia effects on [18F]FDG uptake in mouse brain and heart using small animal PET. Nucl Med Biol 31 (2004) 251-256
23. Kudo T., Fukuchi K., Annala A.J., et al. Noninvasive measurement of myocardial activity concentrations and perfusion defect sizes in rats with a new small-animal positron emission tomograph. Circulation 106 (2002) 118-123
24. Xu M., Uemura R., Dai Y., Wang Y., Pasha Z., and Ashraf M. In vitro and in vivo effects of bone marrow stem cells on cardiac structure and function. J Mol Cell Cardiol 42 (2007) 441-448
25. Engel F.B., Hsieh P.C., Lee R.T., and Keating M.T. FGF1/p38 MAP kinase inhibitor therapy induces cardiomyocyte mitosis, reduces scarring, and rescues function after myocardial infarction. Proc Natl Acad Sci U S A 103 (2006) 15546-15551
26. Tateishi K., Ashihara E., Honsho S., et al. Human cardiac stem cells exhibit mesenchymal features and are maintained through Akt/GSK-3beta signaling. Biochem Biophys Res Commun 352 (2007) 635-641
27. Barile L., Chimenti I., Gaetani R., et al. Cardiac stem cells: isolation, expansion and experimental use for myocardial regeneration. Nat Clin Pract Cardiovasc Med 4 (2007) Suppl 1:S9-14
28. Bearzi C., Rota M., Hosoda T., et al. Human cardiac stem cells. Proc Natl Acad Sci U S A 104 (2007) 14068-14073
29. Schelbert H.R., Inubushi M., and Ross R.S. PET imaging in small animals. J Nucl Cardiol 10 (2003) 513-520
30. Lyngbaek S., Schneider M., Hansen J.L., and Sheikh S.P. Cardiac regeneration by resident stem and progenitor cells in the adult heart. Basic Res Cardiol 102 (2007) 101-114
31. Oyama T., Nagai T., Wada H., et al. Cardiac side population cells have a potential to migrate and differentiate into cardiomyocytes in vitro and in vivo. J Cell Biol 176 (2007) 329-341
32. Rosenblatt-Velin N., Lepore M.G., Cartoni C., Beermann F., and Pedrazzini T. FGF-2 controls the differentiation of resident cardiac precursors into functional cardiomyocytes. J Clin Invest 115 (2005) 1724-1733
33. Tateishi K., Ashihara E., Takehara N., et al. Clonally amplified cardiac stem cells are regulated by Sca-1 signaling for efficient cardiovascular regeneration. J Cell Sci 120 (2007) 1791-1800
34. Garry D.J., and Martin C.M. Cardiac regeneration: self-service at the pump. Circ Res 95 (2004) 852-854
35. McLaughlin L., Zhu G., Mistry M., et al. Apolipoprotein J/clusterin limits the severity of murine autoimmune myocarditis. J Clin Invest 106 (2000) 1105-1113
36. Zhang M., Methot D., Poppa V., Fujio Y., Walsh K., and Murry C.E. Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies. J Mol Cell Cardiol 33 (2001) 907-921
37. van der Bogt K.E., Schrepfer S., Sheikh A.Y., et al. Comparison of transplantation of adipose tissue- and bone marrow-derived mesenchymal stem cells in the infarcted heart. Transplantation 87 (2009) 642-652
38. Cao F., Wagner R.A., Wilson K.D., et al. Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes. PLoS ONE 3 (2008) e3474
39. Mendell J.R., Kissel J.T., Amato A.A., et al. Myoblast transfer in the treatment of Duchenne's muscular dystrophy. N Engl J Med 333 (1995) 832-838
40. Wollert K.C., and Drexler H. Clinical applications of stem cells for the heart. Circ Res 96 (2005) 151-163
41. Gnecchi M., He H., Liang O.D., et al. Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells. Nat Med 11 (2005) 367-368
42. Cao F., Sadrzadeh Rafie A.H., Abilez O.J., et al. In vivo imaging and evaluation of different biomatrices for improvement of stem cell survival. J Tissue Eng Regen Med 1 (2007) 465-468
43. Laflamme M.A., Chen K.Y., Naumova A.V., et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol 25 (2007) 1015-1024
44. Muraski J.A., Rota M., Misao Y., et al. Pim-1 regulates cardiomyocyte survival downstream of Akt. Nat Med 13 (2007) 1467-1475
45. Tillmanns J., Rota M., Hosoda T., et al. Formation of large coronary arteries by cardiac progenitor cells. Proc Natl Acad Sci U S A 105 (2008) 1668-1673