The heat is on: Thermodynamic analysis in fragment-based drug discovery

Drug Discovery Today: Technologies

Volumn 7, Issue 3, 2010, Pages

  Edink, Ewald ^a   Jansen, Chimed ^a   Leurs, Rob ^a   De Esch, Iwan J P ^a  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A1 RECEPTOR; CAFFEINE; MAJOR URINARY PROTEIN; MATRIX METALLOPROTEINASE; MATRIX METALLOPROTEINASE INHIBITOR; PHEROMONE DERIVATIVE; THEOPHYLLINE; UNCLASSIFIED DRUG; XANTHINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BIOSENSOR; COMPLEX FORMATION; DRUG DEVELOPMENT; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG RESEARCH; ENTHALPY; ENTROPY; INTERMETHOD COMPARISON; ISOTHERMAL TITRATION CALORIMETRY; MOLECULAR INTERACTION; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN INTERACTION; SURFACE PLASMON RESONANCE; THERMODYNAMICS;

EID: 78650750341     PISSN: 17406749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ddtec.2010.12.001     Document Type: Review

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