Thermodynamics of 5-HT3 receptor binding discriminates agonistic from antagonistic behaviour

European Journal of Pharmacology

Volumn 298, Issue 3, 1996, Pages 329-334

  Borea, Pier Andrea ^a,b   Dalpiaz, Alessandro ^a   Gessi, Stefania ^a   Gilli, Gastone ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b Istituto di Farmacologia   (Italy)

Author keywords

5 HT3 receptor; Agonist and antagonist discrimination; Binding thermodynamics; Thermodynamic compensation

Indexed keywords

1 (3 CHOROPHENYL)PIPERAZINE; 1 (3 TRIFLUOROMETHYLPHENYL)PIPERAZINE; 1 METHYL 3 INDAZOLECARBOXYLIC ACID N TROPANYLAMIDE; 2 METHYLSEROTONIN; 5 METHOXYTRYPTAMINE; GRANISETRON; MEMBRANE RECEPTOR; METOCLOPRAMIDE; MIANSERIN; PHENYLBIGUANIDE; QUIPAZINE; RADIOLIGAND; RECEPTOR SUBTYPE; SEROTONIN; SEROTONIN 3 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; UNCLASSIFIED DRUG; SEROTONIN RECEPTOR;

ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BRAIN CORTEX; BRAIN MEMBRANE; CONTROLLED STUDY; ENTHALPY; ENTROPY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; RECEPTOR BINDING; TEMPERATURE; THERMODYNAMICS; ANIMAL; DRUG EFFECT; IN VITRO STUDY; METABOLISM; WISTAR RAT;

ANIMALS; CEREBRAL CORTEX; MALE; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; THERMODYNAMICS;

EID: 0029670134     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-2999(95)00813-6     Document Type: Article

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