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78649509155
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For examples of asymmetric hydrogenation of imines involving P-OP ligands, see refs 3j-3l; however, examples on the use of P-OP ligands in the asymmetric hydrogenation of heteroaromatic compounds are scarce (Rubio, M.; Pizzano, A. Molecules 2010, 15, 7732)
-
For examples of asymmetric hydrogenation of imines involving P-OP ligands, see refs 3j-3l; however, examples on the use of P-OP ligands in the asymmetric hydrogenation of heteroaromatic compounds are scarce (Rubio, M.; Pizzano, A. Molecules 2010, 15, 7732).
-
-
-
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88
-
-
78650672545
-
-
See the Supporting Information for full details
-
See the Supporting Information for full details.
-
-
-
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89
-
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0032476793
-
-
See for example
-
See for example: Lightfoot, A.; Schnider, P.; Pfaltz, A. Angew. Chem., Int. Ed. 1998, 37, 2897
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Schnider, P.2
Pfaltz, A.3
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90
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0038634036
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Pfaltz, A.; Blankenstein, J.; Hilgraf, R.; Hormann, E.; McIntyre, S.; Menges, F.; Schonleber, M.; Smidt, S. P.; Wustenberg, B.; Zimmermann, N. Adv. Synth. Catal. 2003, 345, 33
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Menges, F.6
Schonleber, M.7
Smidt, S.P.8
Wustenberg, B.9
Zimmermann, N.10
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91
-
-
78650652494
-
-
This assumption was made on the basis of the coincidental NMR data (see the Supporting Information for details) for 5 and for 6 (whose structure was unequivocally elucidated by X-ray analysis)
-
This assumption was made on the basis of the coincidental NMR data (see the Supporting Information for details) for 5 and for 6 (whose structure was unequivocally elucidated by X-ray analysis).
-
-
-
-
92
-
-
0030739748
-
-
The steric environment at this position has proven critical to the catalytic activity of other chiral ligands derived from Sharpless epoxy alcohols, in several asymmetric transformations. See, for example
-
The steric environment at this position has proven critical to the catalytic activity of other chiral ligands derived from Sharpless epoxy alcohols, in several asymmetric transformations. See, for example: Vidal-Ferran, A.; Moyano, A.; Pericas, M. A.; Riera, A. J. Org. Chem. 1997, 62, 4970
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Vidal-Ferran, A.; Moyano, A.; Pericas, M. A.; Riera, A. Tetrahedron Lett. 1997, 38, 8773
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Vidal-Ferran, A.; Bampos, N.; Moyano, A.; Pericas, M. A.; Riera, A.; Sanders, J. K. M. J. Org. Chem. 1998, 63, 6309
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Puigjaner, C.; Vidal-Ferran, A.; Moyano, A.; Pericas, M. A.; Riera, A. J. Org. Chem. 1999, 64, 7902
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96
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0037120175
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Pericas, M. A.; Puigjaner, C.; Riera, A.; Vidal-Ferran, A.; Gómez, M.; Jiménez, F.; Muller, G.; Rocamora, M. Chem. Eur. J. 2002, 8, 4164
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Jiménez, F.6
Muller, G.7
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33748941575
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Jimeno, C.; Vidal-Ferran, A.; Pericas, M. A. Org. Lett. 2006, 8, 3895
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98
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35948959734
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Popa, D.; Puigjaner, C.; Gómez, M.; Benet-Buchholz, J.; Vidal-Ferran, A.; Pericas, M. A. Adv. Synth. Catal. 2007, 349, 2265
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Popa, D.1
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Benet-Buchholz, J.4
Vidal-Ferran, A.5
Pericas, M.A.6
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99
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67650506915
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Popa, D.; Marcos, R.; Sayalero, S.; Vidal-Ferran, A.; Pericas, M. A. Adv. Synth. Catal. 2009, 351, 1539
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Popa, D.1
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Vidal-Ferran, A.4
Pericas, M.A.5
-
100
-
-
0345711474
-
-
For a general reference on additive effects, see: For details on specific additives, see: References 6u and 7c, for NBS
-
For a general reference on additive effects, see: Vogl, E. M.; Groger, H.; Shibasaki, M. Angew. Chem., Int. Ed. 1999, 38, 1570 For details on specific additives, see: References 6u and 7c, for NBS.
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-
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Vogl, E.M.1
Groger, H.2
Shibasaki, M.3
-
101
-
-
78650639094
-
-
Reference 5a, for iodine
-
Reference 5a, for iodine.
-
-
-
-
102
-
-
78650646467
-
-
Reference 7b, for TFA and p -toluenesulfonic and triflic acids
-
Reference 7b, for TFA and p -toluenesulfonic and triflic acids.
-
-
-
-
103
-
-
78650643851
-
-
Reference 5t, for camphorsulfonic acids
-
Reference 5t, for camphorsulfonic acids.
-
-
-
-
104
-
-
78650651105
-
-
The use of ammonium or quinolinium chloride as additive has been reported by Feringa (6t) and Zhou. (7l) We chose adding anhydrous HCl (10 mol %) to generate in situ the corresponding hydrochloride of each substrate. Greater amounts of HCl (up to stoichiometric quantity) did not provide any improvement
-
The use of ammonium or quinolinium chloride as additive has been reported by Feringa (6t) and Zhou. (7l) We chose adding anhydrous HCl (10 mol %) to generate in situ the corresponding hydrochloride of each substrate. Greater amounts of HCl (up to stoichiometric quantity) did not provide any improvement.
-
-
-
-
105
-
-
0345211465
-
-
Balint, J.; Egri, G.; Fogassy, E.; Bocskei, Z.; Simon, K.; Gajary, A.; Friesz, A. Tetrahedron: Asymmetry 1999, 10, 1079
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(1999)
Tetrahedron: Asymmetry
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, pp. 1079
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Balint, J.1
Egri, G.2
Fogassy, E.3
Bocskei, Z.4
Simon, K.5
Gajary, A.6
Friesz, A.7
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