Quercetin induces tumor-selective apoptosis through downregulation of Mcl-1 and activation of bax

Clinical Cancer Research

Volumn 16, Issue 23, 2010, Pages 5679-5691

  Cheng, Senping ^a   Gao, Ning ^a   Zhang, Zhuo ^a   Chen, Gang ^a   Budhraja, Amit ^a   Ke, Zunji ^a   Son, Young Ok ^a   Wang, Xin ^a   Luo, Jia ^a   Shi, Xianglin ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CYTOCHROME C; PROTEIN BAX; PROTEIN MCL 1; QUERCETIN; SMALL INTERFERING RNA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN U937; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; TUMOR GROWTH; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HL-60 CELLS; HUMANS; JURKAT CELLS; MICE; MICE, NUDE; PROTO-ONCOGENE PROTEINS C-BCL-2; QUERCETIN; RNA, SMALL INTERFERING; SUBSTRATE SPECIFICITY; TRANSCRIPTIONAL ACTIVATION; U937 CELLS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 78650334862     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-10-1565     Document Type: Article

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