-
1
-
-
1842513660
-
Effects of peucedanum praeruptorum dunn and dl-Praeruptorin A on IL-6 Level and Fas, bax, bcl-2 protein expressions in ischemiareperfusion myocardium of rats
-
Chang TH, Liu XY, Zhang XH, Xing J, Wang HL. (2003). Effects of Peucedanum Praeruptorum Dunn and dl-Praeruptorin A on IL-6 Level and Fas, bax, bcl-2 protein expressions in ischemiareperfusion myocardium of rats. Zhongguo Yi Ke Da Xue Xue Bao 32: 1-6.
-
(2003)
Zhongguo Yi Ke Da Xue Xue Bao
, vol.32
, pp. 1-6
-
-
Chang, T.H.1
Liu, X.Y.2
Zhang, X.H.3
Xing, J.4
Wang, H.L.5
-
2
-
-
0022899067
-
Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: An overview
-
Drayer DE. (1986). Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: An overview. Clin Pharmacol Ther 40:125-133.
-
(1986)
Clin Pharmacol Ther
, vol.40
, pp. 125-133
-
-
Drayer, D.E.1
-
3
-
-
0033680461
-
Rotavirus alters paracellular permeability and energy metabolism in Caco-2 cells
-
Dickman KG, Hempson SJ, Anderson J, Lippe S, Zhao L, Burakoff R, Shaw RD. (2000). Rotavirus alters paracellular permeability and energy metabolism in Caco-2 cells. Am J Physiol Gastrointest Liver Physiol 279:G757-G766.
-
(2000)
Am J Physiol Gastrointest Liver Physiol
, vol.279
-
-
Dickman, K.G.1
Hempson, S.J.2
Anderson, J.3
Lippe, S.4
Zhao, L.5
Burakoff, R.6
Shaw, R.D.7
-
4
-
-
0035152853
-
CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies
-
Engman HA, Lennernäs H, Taipalensuu J, Otter C, Leidvik B, Artursson P. (2001). CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies. J Pharm Sci 90:1736-1751.
-
(2001)
J Pharm Sci
, vol.90
, pp. 1736-1751
-
-
Engman, H.A.1
Lennernäs, H.2
Taipalensuu, J.3
Otter, C.4
Leidvik, B.5
Artursson, P.6
-
5
-
-
0032468256
-
Effect of Pd-Ia on elctrophysiological proterties of guinea pig wenticular cell
-
Feng WY, Li JM, Zhang KY. (1998). Effect of Pd-Ia on elctrophysiological proterties of guinea pig wenticular cell. Zhongguo Yao Xue Za Zhi 33: 660-662.
-
(1998)
Zhongguo Yao Xue Za Zhi
, vol.33
, pp. 660-662
-
-
Feng, W.Y.1
Li, J.M.2
Zhang, K.Y.3
-
6
-
-
0027180795
-
Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers
-
Hunter J, Hirst BH, Simmons NL. (1993). Drug absorption limited by P-glycoprotein-mediated secretory drug transport in human intestinal epithelial Caco-2 cell layers. Pharm Res 10:743-749.
-
(1993)
Pharm Res
, vol.10
, pp. 743-749
-
-
Hunter, J.1
Hirst, B.H.2
Simmons, N.L.3
-
7
-
-
22944464763
-
IDentification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption
-
Imai T, Imoto M, Sakamoto H, Hashimoto M. (2005). IDentification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption. Drug Metab Dispos 33:1185-1190.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1185-1190
-
-
Imai, T.1
Imoto, M.2
Sakamoto, H.3
Hashimoto, M.4
-
8
-
-
33748901615
-
Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine
-
Imai T, Taketani M, Shii M, Hosokawa M, Chiba K. (2006). Substrate specificity of carboxylesterase isozymes and their contribution to hydrolase activity in human liver and small intestine. Drug Metab Dispos 34:1734-1741.
-
(2006)
Drug Metab Dispos
, vol.34
, pp. 1734-1741
-
-
Imai, T.1
Taketani, M.2
Shii, M.3
Hosokawa, M.4
Chiba, K.5
-
9
-
-
0035396501
-
Isolation of praeruptorins A and B from Peucedanum praeruptorum Dunn., and their general pharmacological evaluation in comparison with extracts of drug
-
Mei L, Nicoletti M, Battinelli L, Mazzanti G. (2001). Isolation of praeruptorins A and B from Peucedanum praeruptorum Dunn., and their general pharmacological evaluation in comparison with extracts of drug. Il Farmaco 56: 417-420.
-
(2001)
Il Farmaco
, vol.56
, pp. 417-420
-
-
Mei, L.1
Nicoletti, M.2
Battinelli, L.3
Mazzanti, G.4
-
10
-
-
0030444801
-
Stereoselective and carrier-mediated transport of monocarboxylic acids across Caco-2 cells
-
Ogihara T, Tamai I, Takanaga H, Sai Y, Tsuji A. (1996). Stereoselective and carrier-mediated transport of monocarboxylic acids across Caco-2 cells. Pharm Res 13:1828-1832.
-
(1996)
Pharm Res
, vol.13
, pp. 1828-1832
-
-
Ogihara, T.1
Tamai, I.2
Takanaga, H.3
Sai, Y.4
Tsuji, A.5
-
11
-
-
4344594700
-
Transport characteristics of fexofenadine in the Caco-2 cell model
-
Petri N, Tannergren C, Rungstad D, Lennernäs H. (2004). Transport characteristics of fexofenadine in the Caco-2 cell model. Pharm Res 21:1398-1404.
-
(2004)
Pharm Res
, vol.21
, pp. 1398-1404
-
-
Petri, N.1
Tannergren, C.2
Rungstad, D.3
Lennernäs, H.4
-
12
-
-
0642276740
-
2+, Mg(2+)-ATPase activity in renovascular hypertensive rats
-
2+, Mg(2+)-ATPase activity in renovascular hypertensive rats. Yao Xue Xue Bao 37:401-404.
-
(2002)
Yao Xue Xue Bao
, vol.37
, pp. 401-404
-
-
Rao, M.R.1
Sun, L.2
Zhang, X.W.3
-
13
-
-
77952138043
-
Characterization of metabolism and in vitro permeability study of notoginsenoside R1 from radix notoginseng
-
Ruan JQ, Leong WI, Yan R, Wang YT. (2010). Characterization of metabolism and in vitro permeability study of notoginsenoside R1 from Radix notoginseng. J Agric Food Chem 58:5770-5776.
-
(2010)
J Agric Food Chem
, vol.58
, pp. 5770-5776
-
-
Ruan, J.Q.1
Leong, W.I.2
Yan, R.3
Wang, Y.T.4
-
14
-
-
0036805724
-
Comparison of human duoDenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs
-
Sun D, Lennernas H, Welage LS, Barnett JL, Landowski CP, Foster D, Fleisher D, Lee KD, Amidon GL. (2002). Comparison of human duoDenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs. Pharm Res 19:1400-1416.
-
(2002)
Pharm Res
, vol.19
, pp. 1400-1416
-
-
Sun, D.1
Lennernas, H.2
Welage, L.S.3
Barnett, J.L.4
Landowski, C.P.5
Foster, D.6
Fleisher, D.7
Lee, K.D.8
Amidon, G.L.9
-
15
-
-
0033739725
-
Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine
-
Suzuki H, Sugiyama Y. (2000). Role of metabolic enzymes and efflux transporters in the absorption of drugs from the small intestine. Eur J Pharm Sci 12:3-12.
-
(2000)
Eur J Pharm Sci
, vol.12
, pp. 3-12
-
-
Suzuki, H.1
Sugiyama, Y.2
-
16
-
-
0034811602
-
Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers
-
Taipalensuu J, Törnblom H, Lindberg G, Einarsson C, Sjöqvist F, Melhus H, Garberg P, Sjöström B, Lundgren B, Artursson P. (2001). Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers. J Pharmacol Exp Ther 299:164-170.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 164-170
-
-
Taipalensuu, J.1
Törnblom, H.2
Lindberg, G.3
Einarsson, C.4
Sjöqvist, F.5
Melhus, H.6
Garberg, P.7
Sjöström, B.8
Lundgren, B.9
Artursson, P.10
-
17
-
-
0035997335
-
Characterization of mefenamic acid-guaiacol ester: Stability and transport across Caco-2 cell monolayers
-
Tantishaiyakul V, Wiwattanawongsa K, Pinsuwan S, Kasiwong S, Phadoongsombut N, Kaewnopparat S, Kaewnopparat N, Rojanasakul Y. (2002). Characterization of mefenamic acid-guaiacol ester: Stability and transport across Caco-2 cell monolayers. Pharm Res 19:1013-1018.
-
(2002)
Pharm Res
, vol.19
, pp. 1013-1018
-
-
Tantishaiyakul, V.1
Wiwattanawongsa, K.2
Pinsuwan, S.3
Kasiwong, S.4
Phadoongsombut, N.5
Kaewnopparat, S.6
Kaewnopparat, N.7
Rojanasakul, Y.8
-
18
-
-
0030845278
-
Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver
-
Takai S, Matsuda A, Usami Y, Adachi T, Sugiyama T, Katagiri Y, Tatematsu M, Hirano K. (1997). Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver. Biol Pharm Bull 20:869-873.
-
(1997)
Biol Pharm Bull
, vol.20
, pp. 869-873
-
-
Takai, S.1
Matsuda, A.2
Usami, Y.3
Adachi, T.4
Sugiyama, T.5
Katagiri, Y.6
Tatematsu, M.7
Hirano, K.8
-
19
-
-
33751171573
-
Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol
-
Tang M, Mukundan M, Yang J, Charpentier N, LeCluyse EL, Black C, Yang D, Shi D, Yan B. (2006). Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol. J Pharmacol Exp Ther 319:1467-1476.
-
(2006)
J Pharmacol Exp Ther
, vol.319
, pp. 1467-1476
-
-
Tang, M.1
Mukundan, M.2
Yang, J.3
Charpentier, N.4
LeCluyse, E.L.5
Black, C.6
Yang, D.7
Shi, D.8
Yan, B.9
-
20
-
-
22944464763
-
IDentification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption
-
Teruko I, Masumi L, Hisae S, Mitsuru H. (2005). IDentification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption. Drug Metab Dispos 33: 1185-1190.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 1185-1190
-
-
Teruko, I.1
Masumi, L.2
Hisae, S.3
Mitsuru, H.4
-
21
-
-
84915774788
-
-
The state pharmacopoeia commission of P. R. China. Peucedani Radix. Beijing, China: Chemical industry press
-
The state pharmacopoeia commission of P. R. China. (2010). Peucedani Radix. In: Pharmacopoeia of people's republic of China, Beijing, China: Chemical industry press. Vol I:187.
-
(2010)
Pharmacopoeia of people's republic of China
, vol.1
, pp. 187
-
-
-
22
-
-
0037159193
-
EviDence for a plasma membrane-mediated permeability barrier to Tat basic domain in well-differentiated epithelial cells: Lack of correlation with heparan sulfate
-
Violini S, Sharma V, Prior JL, Dyszlewski M, Worms DP. (2002). EviDence for a plasma membrane-mediated permeability barrier to Tat basic domain in well-differentiated epithelial cells: Lack of correlation with heparan sulfate. BioChemistry 41: 12652-12661.
-
(2002)
BioChemistry
, vol.41
, pp. 12652-12661
-
-
Violini, S.1
Sharma, V.2
Prior, J.L.3
Dyszlewski, M.4
Worms, D.P.5
-
23
-
-
0032524982
-
Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells
-
Walgren RA, Walle UK, Walle T. (1998). Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells. Biochem Pharmacol 55:1721-1727.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1721-1727
-
-
Walgren, R.A.1
Walle, U.K.2
Walle, T.3
-
24
-
-
0029166902
-
Effect of dl-praeruptorin A on delayed outward potassium current in single ventricular cell of guunea pig
-
Wang LJ, Li JM, Chang TH, Hao LY. (1995). Effect of dl-praeruptorin A on delayed outward potassium current in single ventricular cell of guunea pig. Chinese Journal of pharmacology and toxicology 9:192-195.
-
(1995)
Chinese Journal of pharmacology and toxicology
, vol.9
, pp. 192-195
-
-
Wang, L.J.1
Li, J.M.2
Chang, T.H.3
Hao, L.Y.4
-
25
-
-
78650197054
-
Effect of Pd-Ia on angiotensin II induced c-Jun protein expression in cadiocytes
-
Wang Y, Yan SX, Jia L, Tian L, Tu X, Lu JX. (2006). Effect of Pd-Ia on angiotensin II induced c-Jun protein expression in cadiocytes. China Pharmacist 9: 685-687.
-
(2006)
China Pharmacist
, vol.9
, pp. 685-687
-
-
Wang, Y.1
Yan, S.X.2
Jia, L.3
Tian, L.4
Tu, X.5
Lu, J.X.6
-
26
-
-
0036158574
-
Inhibitory effects of praeruptorin C on cattle aortic smooth muscle cell proliferation
-
Wei EH, Rao MR, Chen XY, Fan LM, Chen Q. (2002). Inhibitory effects of praeruptorin C on cattle aortic smooth muscle cell proliferation. Acta Pharmacol Sin 23:129-132.
-
(2002)
Acta Pharmacol Sin
, vol.23
, pp. 129-132
-
-
Wei, E.H.1
Rao, M.R.2
Chen, X.Y.3
Fan, L.M.4
Chen, Q.5
-
27
-
-
0042382976
-
Studies of structure modification of (+)-Praeruptorin A
-
Wu XL, Kong LY, Min ZD. (2002). Studies of structure modification of (+)-Praeruptorin A. Acta Pharm Sin 37: 527-534.
-
(2002)
Acta Pharm Sin
, vol.37
, pp. 527-534
-
-
Wu, X.L.1
Kong, L.Y.2
Min, Z.D.3
-
28
-
-
0030990079
-
In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man-fact or myth
-
Yee S. (1997). In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man-fact or myth. Pharm Res 14:763-766.
-
(1997)
Pharm Res
, vol.14
, pp. 763-766
-
-
Yee, S.1
-
29
-
-
77953538497
-
(+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis
-
Xu Z, Wang X, Dai Y, Kong L, Wang F, Xu H, Lu D, Song J, Hou Z. (2010). (+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis. Chem Biol Interact 186:239-246.
-
(2010)
Chem Biol Interact
, vol.186
, pp. 239-246
-
-
Xu, Z.1
Wang, X.2
Dai, Y.3
Kong, L.4
Wang, F.5
Xu, H.6
Lu, D.7
Song, J.8
Hou, Z.9
-
30
-
-
0034842409
-
Effect of dl-praeruptorin A on ATP sensitive potassium channels in human cortical neurons
-
Zhang SL, Li JM, Xiao QH, Wu AH, Zhao Q, Yang GR, Zhang KY. (2001). Effect of dl-praeruptorin A on ATP sensitive potassium channels in human cortical neurons. Acta Pharmacol Sin 22:813-816.
-
(2001)
Acta Pharmacol Sin
, vol.22
, pp. 813-816
-
-
Zhang, S.L.1
Li, J.M.2
Xiao, Q.H.3
Wu, A.H.4
Zhao, Q.5
Yang, G.R.6
Zhang, K.Y.7
-
31
-
-
0032879905
-
Relaxant effects of pyranocoumarin compounds isolated from a chinese medical plant, bai-hua qian-hu, on isolated rabbit tracheas and pulmonary arteries
-
Zhao NC, Jin WB, Zhang XH, Guan FL, Sun YB, Adachi H, Okuyama T. (1999). Relaxant effects of pyranocoumarin compounds isolated from a Chinese medical plant, Bai-Hua Qian-Hu, on isolated rabbit tracheas and pulmonary arteries. Biol Pharm Bull 22:984-987.
-
(1999)
Biol Pharm Bull
, vol.22
, pp. 984-987
-
-
Zhao, N.C.1
Jin, W.B.2
Zhang, X.H.3
Guan, F.L.4
Sun, Y.B.5
Adachi, H.6
Okuyama, T.7
-
32
-
-
33645841349
-
Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana
-
Zhu HJ, Wang JS, Markowitz JS, DonoVan JL, Gibson BB, Gefroh HA, DeVane CL. (2006). Characterization of P-glycoprotein inhibition by major cannabinoids from marijuana. J Pharmacol Exp Ther 317: 850-857.
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 850-857
-
-
Zhu, H.J.1
Wang, J.S.2
Markowitz, J.S.3
DonoVan, J.L.4
Gibson, B.B.5
Gefroh, H.A.6
DeVane, C.L.7
|