-
1
-
-
45549092417
-
Mechanisms of high-glucose/insulin-mediated desensitization of acute insulin-stimulated glucose transport and Akt activation
-
Robinson KA, Buse MG. Mechanisms of high-glucose/insulin-mediated desensitization of acute insulin-stimulated glucose transport and Akt activation. Am J Physiol Endocrinol Metab 2008;294:E870-E881
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Robinson, K.A.1
Buse, M.G.2
-
2
-
-
8744272467
-
Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin
-
Marchetti P, Del Guerra S, Marselli L, Lupi R, Masini M, Pollera M, Bugliani M, Boggi U, Vistoli F, Mosca F, Del Prato S. Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin. J Clin Endocrinol Metab 2004;89:5535-5541
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5535-5541
-
-
Marchetti, P.1
Del Guerra, S.2
Marselli, L.3
Lupi, R.4
Masini, M.5
Pollera, M.6
Bugliani, M.7
Boggi, U.8
Vistoli, F.9
Mosca, F.10
Del Prato, S.11
-
3
-
-
0026602267
-
Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance
-
Mitrakou A, Kelley D, Mokan M, Veneman T, Pangburn T, Reilly J, Gerich J. Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance. N Engl J Med 1992;326:22-29
-
(1992)
N Engl J Med
, vol.326
, pp. 22-29
-
-
Mitrakou, A.1
Kelley, D.2
Mokan, M.3
Veneman, T.4
Pangburn, T.5
Reilly, J.6
Gerich, J.7
-
4
-
-
0035125001
-
β-cell dysfunction and failure in type 2 diabetes: Potential mechanisms
-
Porte D Jr, Kahn SE. β-cell dysfunction and failure in type 2 diabetes: potential mechanisms. Diabetes 2001;1(Suppl.):S160-S163
-
(2001)
Diabetes
, vol.1
, Issue.SUPPL.
-
-
Porte Jr., D.1
Kahn, S.E.2
-
5
-
-
33749211033
-
β cell failure: Causes and consequences
-
September:13-18
-
Kahn SE. β cell failure: causes and consequences. Int J Clin Pract 2001;September:13-18
-
(2001)
Int J Clin Pract
-
-
Kahn, S.E.1
-
6
-
-
0034678739
-
The importance of the β-cell in the pathogenesis of type 2 diabetes mellitus
-
Kahn SE. The importance of the β-cell in the pathogenesis of type 2 diabetes mellitus. Am J Med 2000;108(Suppl. 6a):2S-8S
-
(2000)
Am J Med
, vol.108
, Issue.SUPPL. 6A
-
-
Kahn, S.E.1
-
7
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes. Diabetes 2003;52:102-110
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
8
-
-
12344323484
-
Type 2 diabetes - A matter of β-cell life and death?
-
Rhodes CJ. Type 2 diabetes - a matter of β-cell life and death? Science 2005;307:380-384
-
(2005)
Science
, vol.307
, pp. 380-384
-
-
Rhodes, C.J.1
-
9
-
-
0036315888
-
Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: Evidence that α-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated
-
Lupi R, Dotta F, Marselli L, Del Guerra S, Masini M, Santangelo C, Patane G, Boggi U, Piro S, Anello M, Bergamini E, Mosca F, Di Mario U, Del Prato S, Marchetti P. Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that α-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated. Diabetes 2002;51:1437-1442
-
(2002)
Diabetes
, vol.51
, pp. 1437-1442
-
-
Lupi, R.1
Dotta, F.2
Marselli, L.3
Del Guerra, S.4
Masini, M.5
Santangelo, C.6
Patane, G.7
Boggi, U.8
Piro, S.9
Anello, M.10
Bergamini, E.11
Mosca, F.12
Di Mario, U.13
Del Prato, S.14
Marchetti, P.15
-
10
-
-
0033524937
-
Tissue-specific knockout of the insulin receptor in pancreatic α cells creates an insulin secretory defect similar to that in type 2 diabetes
-
Kulkarni RN, Bruning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR. Tissue-specific knockout of the insulin receptor in pancreatic α cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell 1999;96:329-339
-
(1999)
Cell
, vol.96
, pp. 329-339
-
-
Kulkarni, R.N.1
Bruning, J.C.2
Winnay, J.N.3
Postic, C.4
Magnuson, M.A.5
Kahn, C.R.6
-
11
-
-
0348048485
-
Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in αIRKO mice
-
Otani K, Kulkarni RN, Baldwin AC, Krutzfeldt J, Ueki K, Stoffel M, Kahn CR, Polonsky KS. Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in αIRKO mice. Am J Physiol Endocrinol Metab 2004;286:E41-E49
-
(2004)
Am J Physiol Endocrinol Metab
, vol.286
-
-
Otani, K.1
Kulkarni, R.N.2
Baldwin, A.C.3
Krutzfeldt, J.4
Ueki, K.5
Stoffel, M.6
Kahn, C.R.7
Polonsky, K.S.8
-
12
-
-
0036578921
-
α-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass
-
Kulkarni RN, Holzenberger M, Shih DQ, Ozcan U, Stoffel M, Magnuson MA, Kahn CR. α-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter β-cell mass. Nat Genet 2002;31:111-115
-
(2002)
Nat Genet
, vol.31
, pp. 111-115
-
-
Kulkarni, R.N.1
Holzenberger, M.2
Shih, D.Q.3
Ozcan, U.4
Stoffel, M.5
Magnuson, M.A.6
Kahn, C.R.7
-
13
-
-
0036791398
-
Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor
-
Xuan S, Kitamura T, Nakae J, Politi K, Kido Y, Fisher PE, Morroni M, Cinti S, White MF, Herrera PL, Accili D, Efstratiadis A. Defective insulin secretion in pancreatic β cells lacking type 1 IGF receptor. J Clin Invest 2002;110:1011-1019
-
(2002)
J Clin Invest
, vol.110
, pp. 1011-1019
-
-
Xuan, S.1
Kitamura, T.2
Nakae, J.3
Politi, K.4
Kido, Y.5
Fisher, P.E.6
Morroni, M.7
Cinti, S.8
White, M.F.9
Herrera, P.L.10
Accili, D.11
Efstratiadis, A.12
-
14
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001;414:799-806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
15
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic V, Suzuki A, de la Pompa JL, Brothers GM, Mirtsos C, Sasaki T, Ruland J, Penninger JM, Siderovski DP, Mak TW. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell 1998;95:29-39
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
16
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck PA, Pershouse MA, Jasser SA, Yung WK, Lin H, Ligon AH, Langford LA, Baumgard ML, Hattier T, Davis T, Frye C, Hu R, Swedlund B, Teng DH, Tavtigian SV. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet 1997;15:356-362
-
(1997)
Nat Genet
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.14
Tavtigian, S.V.15
-
17
-
-
0038067837
-
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production
-
Kimura T, Suzuki A, Fujita Y, Yomogida K, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T. Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production. Development 2003;130:1691-1700
-
(2003)
Development
, vol.130
, pp. 1691-1700
-
-
Kimura, T.1
Suzuki, A.2
Fujita, Y.3
Yomogida, K.4
Lomeli, H.5
Asada, N.6
Ikeuchi, M.7
Nagy, A.8
Mak, T.W.9
Nakano, T.10
-
18
-
-
34147198367
-
Role of tumor suppressor PTEN in tumor necrosis factor α-induced inhibition of insulin signaling in murine skeletal muscle C2C12 cells
-
Lo YT, Tzeng TF, Liu IM. Role of tumor suppressor PTEN in tumor necrosis factor α-induced inhibition of insulin signaling in murine skeletal muscle C2C12 cells. Horm Metab Res 2007;39:173-178
-
(2007)
Horm Metab Res
, vol.39
, pp. 173-178
-
-
Lo, Y.T.1
Tzeng, T.F.2
Liu, I.M.3
-
19
-
-
19944430614
-
Muscle-specific Pten deletion protects against insulin resistance and diabetes
-
Wijesekara N, Konrad D, Eweida M, Jefferies C, Liadis N, Giacca A, Crackower M, Suzuki A, Mak TW, Kahn CR, Klip A, Woo M. Muscle-specific Pten deletion protects against insulin resistance and diabetes. Mol Cell Biol 2005;25:1135-1145
-
(2005)
Mol Cell Biol
, vol.25
, pp. 1135-1145
-
-
Wijesekara, N.1
Konrad, D.2
Eweida, M.3
Jefferies, C.4
Liadis, N.5
Giacca, A.6
Crackower, M.7
Suzuki, A.8
Mak, T.W.9
Kahn, C.R.10
Klip, A.11
Woo, M.12
-
20
-
-
85047694402
-
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas
-
Horie Y, Suzuki A, Kataoka E, Sasaki T, Hamada K, Sasaki J, Mizuno K, Hasegawa G, Kishimoto H, Iizuka M, Naito M, Enomoto K, Watanabe S, Mak TW, Nakano T. Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J Clin Invest 2004;113:1774-1783
-
(2004)
J Clin Invest
, vol.113
, pp. 1774-1783
-
-
Horie, Y.1
Suzuki, A.2
Kataoka, E.3
Sasaki, T.4
Hamada, K.5
Sasaki, J.6
Mizuno, K.7
Hasegawa, G.8
Kishimoto, H.9
Iizuka, M.10
Naito, M.11
Enomoto, K.12
Watanabe, S.13
Mak, T.W.14
Nakano, T.15
-
21
-
-
14844340146
-
Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue
-
Kurlawalla-Martinez C, Stiles B, Wang Y, Devaskar SU, Kahn BB, Wu H. Insulin hypersensitivity and resistance to streptozotocin-induced diabetes in mice lacking PTEN in adipose tissue. Mol Cell Biol 2005;25:2498-2510
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2498-2510
-
-
Kurlawalla-Martinez, C.1
Stiles, B.2
Wang, Y.3
Devaskar, S.U.4
Kahn, B.B.5
Wu, H.6
-
22
-
-
10744222107
-
Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity
-
corrected
-
Stiles B, Wang Y, Stahl A, Bassilian S, Lee WP, Kim YJ, Sherwin R, Devaskar S, Lesche R, Magnuson MA, Wu H. Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity [corrected]. Proc Natl Acad Sci U S A 2004;101:2082-2087
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 2082-2087
-
-
Stiles, B.1
Wang, Y.2
Stahl, A.3
Bassilian, S.4
Lee, W.P.5
Kim, Y.J.6
Sherwin, R.7
Devaskar, S.8
Lesche, R.9
Magnuson, M.A.10
Wu, H.11
-
23
-
-
33745030531
-
Essential role of Pten in body size determination and pancreatic β-cell homeostasis in vivo
-
Nguyen KT, Tajmir P, Lin CH, Liadis N, Zhu XD, Eweida M, Tolasa-Karaman G, Cai F, Wang R, Kitamura T, Belsham DD, Wheeler MB, Suzuki A, Mak TW, Woo M. Essential role of Pten in body size determination and pancreatic β-cell homeostasis in vivo. Mol Cell Biol 2006;26:4511-4518
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4511-4518
-
-
Nguyen, K.T.1
Tajmir, P.2
Lin, C.H.3
Liadis, N.4
Zhu, X.D.5
Eweida, M.6
Tolasa-Karaman, G.7
Cai, F.8
Wang, R.9
Kitamura, T.10
Belsham, D.D.11
Wheeler, M.B.12
Suzuki, A.13
Mak, T.W.14
Woo, M.15
-
24
-
-
33645217126
-
Selective deletion of Pten in pancreatic β cells leads to increased islet mass and resistance to STZ-induced diabetes
-
Stiles BL, Kuralwalla-Martinez C, Guo W, Gregorian C, Wang Y, Tian J, Magnuson MA, Wu H. Selective deletion of Pten in pancreatic β cells leads to increased islet mass and resistance to STZ-induced diabetes. Mol Cell Biol 2006;26:2772-2781
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2772-2781
-
-
Stiles, B.L.1
Kuralwalla-Martinez, C.2
Guo, W.3
Gregorian, C.4
Wang, Y.5
Tian, J.6
Magnuson, M.A.7
Wu, H.8
-
25
-
-
33646351975
-
Total insulin and IGF-I resistance in pancreatic β cells causes overt diabetes
-
Ueki K, Okada T, Hu J, Liew CW, Assmann A, Dahlgren GM, Peters JL, Shackman JG, Zhang M, Artner I, Satin LS, Stein R, Holzenberger M, Kennedy RT, Kahn CR, Kulkarni RN. Total insulin and IGF-I resistance in pancreatic β cells causes overt diabetes. Nat Genet 2006;38:583-588
-
(2006)
Nat Genet
, vol.38
, pp. 583-588
-
-
Ueki, K.1
Okada, T.2
Hu, J.3
Liew, C.W.4
Assmann, A.5
Dahlgren, G.M.6
Peters, J.L.7
Shackman, J.G.8
Zhang, M.9
Artner, I.10
Satin, L.S.11
Stein, R.12
Holzenberger, M.13
Kennedy, R.T.14
Kahn, C.R.15
Kulkarni, R.N.16
-
26
-
-
34948834713
-
PTEN expression contributes to the regulation of muscle protein degradation in diabetes
-
Hu Z, Lee IH, Wang X, Sheng H, Zhang L, Du J, Mitch WE. PTEN expression contributes to the regulation of muscle protein degradation in diabetes. Diabetes 2007;56:2449-2456
-
(2007)
Diabetes
, vol.56
, pp. 2449-2456
-
-
Hu, Z.1
Lee, I.H.2
Wang, X.3
Sheng, H.4
Zhang, L.5
Du, J.6
Mitch, W.E.7
-
27
-
-
8444235415
-
Increase of PTEN gene expression in insulin resistance
-
Lo YT, Tsao CJ, Liu IM, Liou SS, Cheng JT. Increase of PTEN gene expression in insulin resistance. Horm Metab Res 2004;36:662-666
-
(2004)
Horm Metab Res
, vol.36
, pp. 662-666
-
-
Lo, Y.T.1
Tsao, C.J.2
Liu, I.M.3
Liou, S.S.4
Cheng, J.T.5
-
28
-
-
0034680877
-
Regulation of gene expression by glucose in pancreatic β-cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3′-kinase
-
da Silva Xavier G, Varadi A, Ainscow EK, Rutter GA. Regulation of gene expression by glucose in pancreatic β-cells (MIN6) via insulin secretion and activation of phosphatidylinositol 3′-kinase. J Biol Chem 2000;275:36269-36277
-
(2000)
J Biol Chem
, vol.275
, pp. 36269-36277
-
-
Da Silva Xavier, G.1
Varadi, A.2
Ainscow, E.K.3
Rutter, G.A.4
-
29
-
-
34548418170
-
Distinct in vivo roles of caspase-8 in β-cells in physiological and diabetes models
-
Liadis N, Salmena L, Kwan E, Tajmir P, Schroer SA, Radziszewska A, Li X, Sheu L, Eweida M, Xu S, Gaisano HY, Hakem R, Woo M. Distinct in vivo roles of caspase-8 in β-cells in physiological and diabetes models. Diabetes 2007;56:2302-2311
-
(2007)
Diabetes
, vol.56
, pp. 2302-2311
-
-
Liadis, N.1
Salmena, L.2
Kwan, E.3
Tajmir, P.4
Schroer, S.A.5
Radziszewska, A.6
Li, X.7
Sheu, L.8
Eweida, M.9
Xu, S.10
Gaisano, H.Y.11
Hakem, R.12
Woo, M.13
-
30
-
-
50449102364
-
Partial deletion of Pten in the hypothalamus leads to growth defects that cannot be rescued by exogenous growth hormone
-
Choi D, Nguyen KT, Wang L, Schroer SA, Suzuki A, Mak TW, Woo M. Partial deletion of Pten in the hypothalamus leads to growth defects that cannot be rescued by exogenous growth hormone. Endocrinology 2008;149:4382-4386
-
(2008)
Endocrinology
, vol.149
, pp. 4382-4386
-
-
Choi, D.1
Nguyen, K.T.2
Wang, L.3
Schroer, S.A.4
Suzuki, A.5
Mak, T.W.6
Woo, M.7
-
31
-
-
0026669756
-
Roles of insulin resistance and β-cell dysfunction in dexamethasone-induced diabetes
-
Ogawa A, Johnson JH, Ohneda M, McAllister CT, Inman L, Alam T, Unger RH. Roles of insulin resistance and β-cell dysfunction in dexamethasone-induced diabetes. J Clin Invest 1992;90:497-504
-
(1992)
J Clin Invest
, vol.90
, pp. 497-504
-
-
Ogawa, A.1
Johnson, J.H.2
Ohneda, M.3
McAllister, C.T.4
Inman, L.5
Alam, T.6
Unger, R.H.7
-
32
-
-
0027146263
-
The relationship of diabetes, loss of glucose-induced insulin secretion, and GLUT2
-
Weir GC. The relationship of diabetes, loss of glucose-induced insulin secretion, and GLUT2. J Diabetes Complications 1993;7:124-129
-
(1993)
J Diabetes Complications
, vol.7
, pp. 124-129
-
-
Weir, G.C.1
-
33
-
-
2942595906
-
Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose
-
da Silva Xavier G, Rutter J, Rutter GA. Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose. Proc Natl Acad Sci U S A 2004;101:8319-8324
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8319-8324
-
-
Da Silva Xavier, G.1
Rutter, J.2
Rutter, G.A.3
-
34
-
-
42449106571
-
Prediabetes and type 2 diabetes in youth: An emerging epidemic disease?
-
Cali AM, Caprio S. Prediabetes and type 2 diabetes in youth: an emerging epidemic disease? Curr Opin Endocrinol Diabetes Obes 2008;15:123-127
-
(2008)
Curr Opin Endocrinol Diabetes Obes
, vol.15
, pp. 123-127
-
-
Cali, A.M.1
Caprio, S.2
-
35
-
-
0842269769
-
Impaired glucose tolerance and reduced β-cell function in overweight Latino children with a positive family history for type 2 diabetes
-
Goran MI, Bergman RN, Avila Q, Watkins M, Ball GD, Shaibi GQ, Weigensberg MJ, Cruz ML. Impaired glucose tolerance and reduced β-cell function in overweight Latino children with a positive family history for type 2 diabetes. J Clin Endocrinol Metab 2004;89:207-212
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 207-212
-
-
Goran, M.I.1
Bergman, R.N.2
Avila, Q.3
Watkins, M.4
Ball, G.D.5
Shaibi, G.Q.6
Weigensberg, M.J.7
Cruz, M.L.8
-
36
-
-
59149089346
-
PTEN deletion and concomitant c-Myc activation do not lead to tumor formation in pancreatic β cells
-
Radziszewska A, Choi D, Nguyen KT, Schroer SA, Tajmir P, Wang L, Suzuki A, Mak TW, Evan GI, Woo M. PTEN deletion and concomitant c-Myc activation do not lead to tumor formation in pancreatic β cells. J Biol Chem 2009;284:2917-2922
-
(2009)
J Biol Chem
, vol.284
, pp. 2917-2922
-
-
Radziszewska, A.1
Choi, D.2
Nguyen, K.T.3
Schroer, S.A.4
Tajmir, P.5
Wang, L.6
Suzuki, A.7
Mak, T.W.8
Evan, G.I.9
Woo, M.10
-
37
-
-
0035210374
-
Islet β cell expression of constitutively active Akt1/PKB α induces striking hypertrophy, hyperplasia, and hyperinsulinemia
-
Bernal-Mizrachi E, Wen W, Stahlhut S, Welling CM, Permutt MA. Islet β cell expression of constitutively active Akt1/PKB α induces striking hypertrophy, hyperplasia, and hyperinsulinemia. J Clin Invest 2001;108:1631-1638
-
(2001)
J Clin Invest
, vol.108
, pp. 1631-1638
-
-
Bernal-Mizrachi, E.1
Wen, W.2
Stahlhut, S.3
Welling, C.M.4
Ma, P.5
-
38
-
-
0034781057
-
Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα
-
Tuttle RL, Gill NS, Pugh W, Lee JP, Koeberlein B, Furth EE, Polonsky KS, Naji A, Birnbaum MJ. Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα. Nat Med 2001;7:1133-1137
-
(2001)
Nat Med
, vol.7
, pp. 1133-1137
-
-
Tuttle, R.L.1
Gill, N.S.2
Pugh, W.3
Lee, J.P.4
Koeberlein, B.5
Furth, E.E.6
Polonsky, K.S.7
Naji, A.8
Birnbaum, M.J.9
|