Partial deletion of Pten in the hypothalamus leads to growth defects that cannot be rescued by exogenous growth hormone

Endocrinology

Volumn 149, Issue 9, 2008, Pages 4382-4386

  Choi, Diana ^a   Nguyen, Kinh Tung T ^a   Wang, Linyuan ^a   Schroer, Stephanie A ^a   Suzuki, Akira ^c   Mak, Tak W ^a,b   Woo, Minna ^a,d,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c AKITA UNIVERSITY   (Japan)

^d ST MICHAEL'S HOSPITAL   (Canada)

^e PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

DRUG VEHICLE; INSULIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RECOMBINANT GROWTH HORMONE; SOMATOMEDIN BINDING PROTEIN 1; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C;

ADENOHYPOPHYSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY GROWTH; BODY SIZE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GENE DELETION; GLUCOSE BLOOD LEVEL; GROWTH DISORDER; GROWTH REGULATION; HORMONE RELEASE; HYPOTHALAMUS; INSULIN BLOOD LEVEL; MALE; MOUSE; NERVE CELL; NERVE CONDUCTION; NONHUMAN; PANCREAS ISLET BETA CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; BODY SIZE; DRUG RESISTANCE; FEMALE; GENE DELETION; GROWTH DISORDERS; GROWTH HORMONE; HYPOTHALAMUS; INSULIN; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PTEN PHOSPHOHYDROLASE; RNA, MESSENGER; TREATMENT FAILURE;

EID: 50449102364     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-1761     Document Type: Article

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