Platelet toll-like receptor expression: The link between "danger" ligands and inflammation

Inflammation and Allergy - Drug Targets

Volumn 9, Issue 5, 2010, Pages 322-333

  Garraud, Olivier ^a,b,c,d   Cognasse, Fabrice ^a,b,c,d  

^a ETABLISSEMENT FRANÇAIS DU SANG   (France)

^b UNIVERSITÉ DE LYON   (France)

^c UNIVERSITÉ JEAN MONNET   (France)

^d GIMAP EA3064   (France)

Author keywords

Inflammation; Innate and adaptive immune response; Platelets; Toll like receptor

Indexed keywords

CHEMOKINE; CYTOKINE; IMMUNOGLOBULIN; INTERLEUKIN 1 RECEPTOR; TOLL LIKE RECEPTOR;

ADAPTIVE IMMUNITY; ARTICLE; EUKARYOTE; HEMOSTASIS; HUMAN; IMMUNOMODULATION; INFECTION; INFLAMMATION; INNATE IMMUNITY; MICROBIAL COLONIZATION; NONHUMAN; PROTEIN DOMAIN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THROMBOCYTE; THROMBOCYTE FUNCTION;

EID: 78650028451     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152810793937991     Document Type: Article

References (168)

1. Weyrich, A.S.; Zimmerman, G.A. Platelets: signaling cells in the immune continuum. Trends Immunol., 2004, 25, 489-95.
2. Elzey, B.D.; Sprague, D.L.; Ratliff, T.L. The emerging role of platelets in adaptive immunity. Cell Immunol., 2005, 238, 1-9.
3. Cognasse, F.; Hamzeh, H.; Chavarin, P.; Acquart, S.; Genin, C.; Garraud, O. Evidence of Toll Like Receptor molecules on human platelets. Immunol. Cell Biol., 2005, 83, 196-98.
4. Cognasse, F.; Boussoulade, F.; Chavarin, P.; Acquart, S.; Fabrigli, P.; Lamy, B.; Garraud, O. Release of potential immunomodulatory factors during platelet storage. Transfusion, 2006, 46, 1184-9.
5. Cognasse, F.; Payrat, J.M.; Corash, L.; Osselaer, J.C.; Garraud, O. Platelet components associated with acute transfusion reactions: the role of platelet-derived soluble CD40 ligand. Blood, 2008, 112, 4779-80.
6. Aslam, R.; Speck, E.R.; Kim, M.; Crow, A.R.; Bang, K.W.; Nestel, F.P.; Ni, H.; Lazarus, A.H.; Freedman, J.; Semple, J.W. Platelet Toll-like receptor expression modulates lipopolysaccharideinduced thrombocytopenia and tumor necrosis factor-alpha production in vivo. Blood, 2006, 107, 637-41.
7. Damas, J.K.; Jensenius, M.; Ueland, T.; Otterdal, K.; Yndestad, A.; Froland, S.S.; Rolain, J.M.; Myrvang, B.; Raoult, D.; Aukrust, P. Increased levels of soluble CD40L in African tick bite fever: possible involvement of TLRs in the pathogenic interaction between Rickettsia africae, endothelial cells, and platelets. J. Immunol., 2006, 177, 2699-706.
8. Fillon, S.; Soulis, K.; Rajasekaran, S.; Benedict-Hamilton, H.; Radin, J.N.; Orihuela, C.J.; El Kasmi, K.C.; Murti, G.; Kaushal, D.; Gaber, M.W.; Weber, J.R.; Murray, P.J.; Tuomanen, E.I. Plateletactivating factor receptor and innate immunity: uptake of grampositive bacterial cell wall into host cells and cell-specific pathophysiology. J. Immunol., 2006, 177, 6182-91.
9. Blair, P.; Rex, S.; Vitseva, O.; Beaulieu, L.; Tanriverdi, K.; Chakrabarti, S.; Hayashi, C.; Genco, C.A.; Iafrati, M.; Freedman, J.E. Stimulation of Toll-Like Receptor 2 in Human Platelets Induces a Thromboinflammatory Response Through Activation of Phosphoinositide 3-Kinase. Circ. Res., 2008, 104, 346-54.
10. Rex, S.; Beaulieu, L.M.; Perlman, D.H.; Vitseva, O.; Blair, P.S.; McComb, M.E.; Costello, C.E.; Freedman, J.E. Immune versus thrombotic stimulation of platelets differentially regulates signalling pathways, intracellular protein-protein interactions, and alpha-granule release. Thromb. Haemost., 2009, 102, 97-110.
11. Andonegui, G.; Kerfoot, S.M.; McNagny, K.; Ebbert, K.V.; Patel, K.D.; Kubes, P. Platelets express functional Toll-like receptor-4. Blood, 2005, 106, 2417-23.
12. Stahl, A.L.; Svensson, M.; Morgelin, M.; Svanborg, C.; Tarr, P.I.; Mooney, J.C.; Watkins, S.L.; Johnson, R.; Karpman, D. Lipopolysaccharide from enterohemorrhagic Escherichia coli binds to platelets via TLR4 and CD62 and is detected on circulating platelets in patients with hemolytic uremic syndrome. Blood, 2006, 108, 167-76.
13. Jayachandran, M.; Brunn, G.J.; Karnicki, K.; Miller, R.S.; Owen, W.G.; Miller, V.M. In vivo effects of lipopolysaccharide and TLR4 on platelet production and activity: implications for thrombotic risk. J. Appl. Physiol., 2007, 102, 429-33.
14. Clark, S.R.; Ma, A.C.; Tavener, S.A.; McDonald, B.; Goodarzi, Z.; Kelly, M.M.; Patel, K.D.; Chakrabarti, S.; McAvoy, E.; Sinclair, G.D.; Keys, E.M.; Allen-Vercoe, E.; Devinney, R.; Doig, C.J.; Green, F.H.; Kubes, P. Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood. Nat. Med. 2007, 13, 463-9.
15. Semple, J.W.; Aslam, R.; Kim, M.; Speck, E.R.; Freedman, J. Platelet-bound lipopolysaccharide enhances Fc receptor-mediated phagocytosis of IgG-opsonized platelets. Blood, 2007, 109, 4803-5.
16. Cognasse, F.; Hamzeh-Cognasse, H.; Lafarge, S.; Delezay, O.; Pozzetto, B.; McNicol, A.; Garraud, O. Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets. Br. J. Haematol., 2008, 141, 84-91.
17. Zhang, G.; Han, J.; Welch, E.J.; Ye, R.D.; Voyno-Yasenetskaya, T.A.; Malik, A.B.; Du, X.; Li, Z. Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway. J. Immunol., 2009, 182, 7997-8004.
18. Shashkin, P.N.; Brown, G.T.; Ghosh, A.; Marathe, G.K.; McIntyre, T.M. Lipopolysaccharide is a direct agonist for platelet RNA splicing. J. Immunol., 2008, 181, 3495-502.
19. Cognasse, F.; Lafarge, S.; Chavarin, P.; Acquart, S.; Garraud, O. Lipopolysaccharide induces sCD40L release through human platelets TLR4, but not TLR2 and TLR9. Intensive Care Med., 2007, 33, 382-4.
20. Janeway, C.A., Jr.; Medzhitov, R. Introduction: the role of innate immunity in the adaptive immune response. Semin. Immunol., 1998, 10, 349-50.
21. Janeway, C.A., Jr.; Medzhitov, R. Innate immune recognition. Annu. Rev. Immunol., 2002, 20, 197-216.
22. Medzhitov, R.; Janeway, C., Jr. Innate immune recognition: mechanisms and pathways. Immunol. Rev., 2000, 173, 89-97.
23. Medzhitov, R.; Janeway, C.A., Jr. Innate immunity: the virtues of a nonclonal system of recognition. Cell, 1997, 91, 295-8.
24. Medzhitov, R.; Janeway, C.A., Jr. Innate immune recognition and control of adaptive immune responses. Semin. Immunol., 1998, 10, 351-3.
25. Kawai, T.; Akira, S. TLR signaling. Semin. Immunol., 2007, 19, 24-32.
26. Lindemann, S.; Tolley, N.D.; Dixon, D.A.; McIntyre, T.M.; Prescott, S.M.; Zimmerman, G.A.; Weyrich, A.S. Activated platelets mediate inflammatory signaling by regulated interleukin 1beta synthesis. J. Cell. Biol., 2001, 154, 485-90.
27. Schwertz, H.; Tolley, N.D.; Foulks, J.M.; Denis, M.M.; Risenmay, B.W.; Buerke, M.; Tilley, R.E.; Rondina, M.T.; Harris, E.M.; Kraiss, L.W.; Mackman, N.; Zimmerman, G.A.; Weyrich, A.S. Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets. J. Exp. Med., 2006, 203, 2433-40.
28. Smyth, S.S.; McEver, R.P.; Weyrich, A.S.; Morrell, C.N.; Hoffman, M.R.; Arepally, G.M.; French, P.A.; Dauerman, H.L.; Becker, R.C. Platelet functions beyond haemostasis. J. Thromb. Haemost., 2009, 7, 1759-66.
29. Andre, P.; Nannizzi-Alaimo, L.; Prasad, S.K.; Phillips, D.R. Platelet-derived CD40L: the switch-hitting player of cardiovascular disease. Circulation, 2002, 106, 896-9.
30. Freedman, J.E. CD40-CD40L and platelet function: beyond hemostasis. Circ. Res., 2003, 92, 944-6.
31. Hamzeh-Cognasse, H.; Cognasse, F.; Palle, S.; Chavarin, P.; Olivier, T.; Delezay, O.; Pozzetto, B.; Garraud, O. Direct contact of platelets and their released products exert different effects on human dendritic cell maturation. BMC Immunol., 2008, 9, 54.
32. Fujii, S.; Liu, K.; Smith, C.; Bonito, A.J.; Steinman, R.M. The linkage of innate to adaptive immunity via maturing dendritic cells in vivo requires CD40 ligation in addition to antigen presentation and CD80/86 costimulation. J. Exp. Med., 2004, 199, 1607-18.
33. Clark, E.A.; Craxton, A. A CD40 bridge between innate and adaptive immunity. Immunity., 2003, 18, 724-5.
34. Clemetson, K.J.; Clemetson, J.M.; Proudfoot, A.E.; Power, C.A.; Baggiolini, M.; Wells, T.N. Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets. Blood, 2000, 96, 4046-54.
35. Gear, A.R.; Camerini, D. Platelet chemokines and chemokine receptors: linking hemostasis, inflammation, and host defense. Microcirculation, 2003, 10, 335-50.
36. Lemaitre, B.; Nicolas, E.; Michaut, L.; Reichhart, J.M.; Hoffmann, J.A. The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell, 1996, 86, 973-83.
37. Netea, M.G.; van der Graaf, C.; Van der Meer, J.W.; Kullberg, B.J. Toll-like receptors and the host defense against microbial pathogens: bringing specificity to the innate-immune system. J. Leukoc. Biol., 2004, 75, 749-55.
38. Pasare, C.; Medzhitov, R. Toll-like receptors and acquired immunity. Semin. Immunol., 2004, 16, 23-6.
39. Werling, D.; Jungi, T.W. TOLL-like receptors linking innate and adaptive immune response. Vet. Immunol. Immunopathol., 2003, 91, 1-12.
40. Krutzik, S.R.; Sieling, P.A.; Modlin, R.L. The role of Toll-like receptors in host defense against microbial infection. Curr. Opin. Immunol., 2001, 13, 104-8.
41. Beg, A.A. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends Immunol., 2002, 23, 509-12.
42. Marshak-Rothstein, A. Toll-like receptors in systemic autoimmune disease. Nat. Rev. Immunol., 2006, 6, 823-35.
43. Akira, S.; Takeda, K. Toll-like receptor signalling. Nat. Rev. Immunol., 2004, 4, 499-511.
44. Moynagh, P.N. TLR signalling and activation of IRFs: revisiting old friends from the NF-kappaB pathway. Trends Immunol., 2005, 26, 469-76.
45. Shiraki, R.; Inoue, N.; Kawasaki, S.; Takei, A.; Kadotani, M.; Ohnishi, Y.; Ejiri, J.; Kobayashi, S.; Hirata, K.; Kawashima, S.; Yokoyama, M. Expression of Toll-like receptors on human platelets. Thromb. Res., 2004, 113, 379-85.
46. Gallucci, S.; Matzinger, P. Danger signals: SOS to the immune system. Curr. Opin. Immunol., 2001, 13, 114-9.
47. Cognasse, F.; Garraud, O. Human platelets exhibit infectiouspathogen binding ligands and participate to inflammation (and more?). Exp. Hematol., 2005, 33, 1081-2.
48. Cognasse, F.; Semple, J.W.; Garraud, O. Platelets as potential immunomodulators: is there a role for platelet toll-like receptors? Curr. Immunol. Rev., 2007, 3, 109-15.
49. Ward, J.R.; Bingle, L.; Judge, H.M.; Brown, S.B.; Storey, R.F.; Whyte, M.K.; Dower, S.K.; Buttle, D.J.; Sabroe, I. Agonists of tolllike receptor (TLR)2 and TLR4 are unable to modulate platelet activation by adenosine diphosphate and platelet activating factor. Thromb Haemost., 2005, 94, 831-8.
50. Malhotra, R.; Priest, R.; Foster, M.R.; Bird, M.I. P-selectin binds to bacterial lipopolysaccharide. Eur. J. Immunol., 1998, 28, 983-8.
51. Patrignani, P.; Di Febbo, C.; Tacconelli, S.; Moretta, V.; Baccante, G.; Sciulli, M.G.; Ricciotti, E.; Capone, M.L.; Antonucci, I.; Guglielmi, M.D.; Stuppia, L.; Porreca, E. Reduced thromboxane biosynthesis in carriers of toll-like receptor 4 polymorphisms in vivo. Blood, 2006, 107, 3572-4.
52. Denis, M.M.; Tolley, N.D.; Bunting, M.; Schwertz, H.; Jiang, H.; Lindemann, S.; Yost, C.C.; Rubner, F.J.; Albertine, K.H.; Swoboda, K.J.; Fratto, C.M.; Tolley, E.; Kraiss, L.W.; McIntyre, T.M.; Zimmerman, G.A.; Weyrich, A.S. Escaping the nuclear confines: signal-dependent pre-mRNA splicing in anucleate platelets. Cell, 2005, 122, 379-91.
53. Bours, V.; Bentires-Alj, M.; Hellin, A.C.; Viatour, P.; Robe, P.; Delhalle, S.; Benoit, V.; Merville, M.P. Nuclear factor-kappa B, cancer, and apoptosis. Biochem. Pharmacol., 2000, 60, 1085-9.
54. Perkins, N.D. Achieving transcriptional specificity with NF-kappa B. Int. J. Biochem. Cell Biol., 1997, 29, 1433-48.
55. Brown, K.; Gerstberger, S.; Carlson, L.; Franzoso, G.; Siebenlist, U. Control of I kappa B-alpha proteolysis by site-specific, signalinduced phosphorylation. Science, 1995, 267, 1485-8.
56. Liou, H.C.; Baltimore, D. Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor system. Curr. Opin. Cell Biol., 1993, 5, 477-87.
57. Rezaei, N. Therapeutic targeting of pattern-recognition receptors. Int. Immunopharmacol., 2006, 6, 863-69.
58. Cristofaro, P.; Opal, S.M. Role of toll-like receptors in infection and immunity: clinical implications. Drugs, 2006, 66, 15-29.
59. O'Neill, L.A. Toll-like receptor signal transduction and the tailoring of innate immunity: a role for Mal? Trends Immunol., 2002, 23, 296-300.
60. Edwards, L.J.; Constantinescu, C.S. Platelet activating factor/platelet activating factor receptor pathway as a potential therapeutic target in autoimmune diseases. Inflamm. Allergy Drug Targets, 2009, 8, 182-90.
61. Ferroni, P.; Basili, S.; Davi, G. Platelet activation, inflammatory mediators and hypercholesterolemia. Curr. Vasc. Pharmacol., 2003, 1, 157-69.
62. Jayaraman, T.; Paget, A.; Shin, Y.S.; Li, X.; Mayer, J.; Chaudhry, H.; Niimi, Y.; Silane, M.; Berenstein, A. TNF-alpha-mediated inflammation in cerebral aneurysms: a potential link to growth and rupture. Vasc. Health Risk Manag., 2008, 4, 805-17.
63. Tunc, S.E.; Aksu, K.; Keser, G.; Oksel, F.; Doganavsargil, E.; Pirildar, T.; Turk, T.; Terzioglu, E.; Huseyinov, A. Plateletactivating factor and P-selectin activities in thrombotic and nonthrombotic Behcet's patients. Rheumatol. Int., 2005, 25, 326-31.
64. Cook, D.N.; Pisetsky, D.S.; Schwartz, D.A. Toll-like receptors in the pathogenesis of human disease. Nat. Immunol., 2004, 5, 975-9.
65. Hopkins, P.A.; Sriskandan, S. Mammalian Toll-like receptors: to immunity and beyond. Clin. Exp. Immunol., 2005, 140, 395-407.
66. Youssefian, T.; Drouin, A.; Masse, J.M.; Guichard, J.; Cramer, E.M. Host defense role of platelets: engulfment of HIV and Staphylococcus aureus occurs in a specific subcellular compartment and is enhanced by platelet activation. Blood, 2002, 99, 4021-9.
67. Siboo, I.R.; Chambers, H.F.; Sullam, P.M. Role of SraP, a Serine- Rich Surface Protein of Staphylococcus aureus, in binding to human platelets. Infect. Immun., 2005, 73, 2273-80.
68. Bayer, A.S.; Kupferwasser, L.I.; Brown, M.H.; Skurray, R.A.; Grkovic, S.; Jones, T.; Mukhopadhay, K.; Yeaman, M.R. Lowlevel resistance of Staphylococcus aureus to thrombin-induced platelet microbicidal protein 1 in vitro associated with qacA gene carriage is independent of multidrug efflux pump activity. Antimicrob Agents Chemother., 2006, 50, 2448-54.
69. Torre, D.; Pugliese, A. Platelets and HIV-1 infection: old and new aspects. Curr. HIV Res., 2008, 6, 411-8.
70. Cognasse, F.; Hamzeh-Cognasse, H.; Berthet, J.; Damien, P.; Lucht, F.; Pozzetto, B.; Garraud, O. Altered release of regulated upon activation, normal T-cell expressed and secreted protein from human, normal platelets: contribution of distinct HIV-1MN gp41 peptides. AIDS, 2009, 23, 2057-9.
71. von Hundelshausen, P.; Weber, C. Platelets as immune cells: bridging inflammation and cardiovascular disease. Circ. Res., 2007, 100, 27-40.
72. Zimmerman, G.A.; McIntyre, T.M.; Prescott, S.M.; Stafforini, D.M. The platelet-activating factor signaling system and its regulators in syndromes of inflammation and thrombosis. Crit. Care Med., 2002, 30, S294-301.
73. Klinger, M.H.; Jelkmann, W. Role of blood platelets in infection and inflammation. J. Interferon. Cytokine Res., 2002, 22, 913-22.
74. Mannaioni, P.F.; Di Bello, M.G.; Masini, E. Platelets and inflammation: role of platelet-derived growth factor, adhesion molecules and histamine. Inflamm. Res., 1997, 46, 4-18.
75. Chaipan, C.; Soilleux, E.J.; Simpson, P.; Hofmann, H.; Gramberg, T.; Marzi, A.; Geier, M.; Stewart, E.A.; Eisemann, J.; Steinkasserer, A.; Suzuki-Inoue, K.; Fuller, G.L.; Pearce, A.C.; Watson, S.P.; Hoxie, J.A.; Baribaud, F.; Pohlmann, S. DC-SIGN and CLEC-2 mediate human immunodeficiency virus type 1 capture by platelets. J. Virol., 2006, 80, 8951-60.
76. Boukour, S.; Masse, J.M.; Benit, L.; Dubart-Kupperschmitt, A.; Cramer, E.M. Lentivirus degradation and DC-SIGN expression by human platelets and megakaryocytes. J. Thromb. Haemost., 2006, 4, 426-35.
77. Zucker-Franklin, D.; Seremetis, S.; Zheng, Z.Y. Internalization of human immunodeficiency virus type I and other retroviruses by megakaryocytes and platelets. Blood, 1990, 75, 1920-3.
78. Bik, T.; Sarov, I.; Livne, A. Interaction between vaccinia virus and human blood platelets. Blood, 1982, 59, 482-7.
79. Chakrabarti, S.; Varghese, S.; Vitseva, O.; Tanriverdi, K.; Freedman, J.E. CD40 ligand influences platelet release of reactive oxygen intermediates. Arterioscler Thromb. Vasc. Biol., 2005, 25, 2428-34.
80. Tang, Y.Q.; Yeaman, M.R.; Selsted, M.E. Antimicrobial peptides from human platelets. Infect. Immun., 2002, 70, 6524-33.
81. Yeaman, M.R. The role of platelets in antimicrobial host defense. Clin. Infect. Dis., 1997, 25, 951-68; quiz 69-70.
82. Inwald, D.P.; McDowall, A.; Peters, M.J.; Callard, R.E.; Klein, N.J. CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation. Circ. Res., 2003, 92, 1041-8.
83. Steinhubl, S.R. Platelets as mediators of inflammation. Hematol. Oncol. Clin. North Am., 2007, 21, 115-21.
84. Huo, Y.; Ley, K.F. Role of platelets in the development of atherosclerosis. Trends. Cardiovasc. Med., 2004, 14, 18-22.
85. Mannel, D.N.; Grau, G.E. Role of platelet adhesion in homeostasis and immunopathology. Mol. Pathol., 1997, 50, 175-85.
86. Solanilla, A.; Pasquet, J.M.; Viallard, J.F.; Contin, C.; Grosset, C.; Dechanet-Merville, J.; Dupouy, M.; Landry, M.; Belloc, F.; Nurden, P.; Blanco, P.; Moreau, J.F.; Pellegrin, J.L.; Nurden, A.T.; Ripoche, J. Platelet-associated CD154 in immune thrombocytopenic purpura. Blood, 2005, 105, 215-8.
87. Boilard, E.; Nigrovic, P.A.; Larabee, K.; Watts, G.F.; Coblyn, J.S.; Weinblatt, M.E.; Massarotti, E.M.; Remold-O'Donnell, E.; Farndale, R.W.; Ware, J.; Lee, D.M. Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science, 2010, 327, 580-3.
88. Zimmerman, G.A.; Weyrich, A.S. Immunology. Arsonists in rheumatoid arthritis. Science, 327, 528-9.
89. Bozza, F.A.; Shah, A.M.; Weyrich, A.S.; Zimmerman, G.A. Amicus or adversary: platelets in lung biology, acute injury, and inflammation. Am. J. Respir. Cell Mol. Biol., 2009, 40, 123-34.
90. Looney, M.R.; Nguyen, J.X.; Hu, Y.; Van Ziffle, J.A.; Lowell, C.A.; Matthay, M.A. Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury. J. Clin. Invest., 2009, 119, 3450-61.
91. Blumberg, N.; Spinelli, S.L.; Francis, C.W.; Taubman, M.B.; Phipps, R.P. The platelet as an immune cell-CD40 ligand and transfusion immunomodulation. Immunol. Res., 2009 [Epub ahead of print].
92. Kaufman, J.; Spinelli, S.L.; Schultz, E.; Blumberg, N.; Phipps, R.P. Release of biologically active CD154 during collection and storage of platelet concentrates prepared for transfusion. J. Thromb. Haemost., 2007, 5, 788-96.
93. Elzey, B.D.; Tian, J.; Jensen, R.J.; Swanson, A.K.; Lees, J.R.; Lentz, S.R.; Stein, C.S.; Nieswandt, B.; Wang, Y.; Davidson, B.L.; Ratliff, T.L. Platelet-mediated modulation of adaptive immunity. A communication link between innate and adaptive immune compartments. Immunity., 2003, 19, 9-19.
94. Cognasse, F.; Hamzeh-Cognasse, H.; Berthet, J.; Damien, P.; Lucht, F.; Pozzetto, B.; Garraud, O. Altered release of regulated upon activation, normal T-cell expressed and secreted protein from human, normal platelets: contribution of distinct HIV-1MN gp41 peptides. AIDS, 2009, 23(15), 2057-2059.
95. Boehlen, F.; Clemetson, K.J. Platelet chemokines and their receptors: what is their relevance to platelet storage and transfusion practice? Transfus. Med., 2001, 11, 403-17.
96. Brandt, E.; Ludwig, A.; Petersen, F.; Flad, H.D. Platelet-derived CXC chemokines: old players in new games. Immunol Rev., 2000, 177, 204-16.
97. Kowalska, M.A.; Ratajczak, J.; Hoxie, J.; Brass, L.F.; Gewirtz, A.; Poncz, M.; Ratajczak, M.Z. Megakaryocyte precursors, megakaryocytes and platelets express the HIV co-receptor CXCR4 on their surface: determination of response to stromal-derived factor-1 by megakaryocytes and platelets. Br. J. Haematol., 1999, 104, 220-9.
98. Wang, J.F.; Liu, Z.Y.; Groopman, J.E. The alpha-chemokine receptor CXCR4 is expressed on the megakaryocytic lineage from progenitor to platelets and modulates migration and adhesion. Blood, 1998, 92, 756-64.
99. Danese, S.; Motte Cd Cde, L.; Fiocchi, C. Platelets in inflammatory bowel disease: clinical, pathogenic, and therapeutic implications. Am. J. Gastroenterol., 2004, 99, 938-45.
100. Harrison, P.; Frelinger, A.L., 3rd; Furman, M.I.; Michelson, A.D. Measuring antiplatelet drug effects in the laboratory. Thromb Res., 2007, 120, 323-36.
101. Herman, A.G. Rationale for the combination of anti-aggregating drugs. Thromb Res., 1998, 92, S17-21.
102. Kozek-Langenecker, S.A. The effects of drugs used in anaesthesia on platelet membrane receptors and on platelet function. Curr. Drug Targets., 2002, 3, 247-58.
103. Michelson, A.D.; Frelinger, A.L., 3rd; Furman, M.I. Current options in platelet function testing. Am. J. Cardiol., 2006, 98, 4N-10N.
104. Colciaghi, F.; Marcello, E.; Borroni, B.; Zimmermann, M.; Caltagirone, C.; Cattabeni, F.; Padovani, A.; Di Luca, M. Platelet APP, ADAM 10 and BACE alterations in the early stages of Alzheimer disease. Neurology, 2004, 62, 498-501.
105. Akerblom, B.; Lindahl, T.L.; Larsson, A. ADP activation induces bFGF binding to platelets in vitro. Ups. J. Med. Sci., 2002, 107, 165-71.
106. Suzuki, M.; Murata, M.; Matsubara, Y.; Uchida, T.; Ishihara, H.; Shibano, T.; Ashida, S.; Soejima, K.; Okada, Y.; Ikeda, Y. Detection of von Willebrand factor-cleaving protease (ADAMTS-13) in human platelets. Biochem. Biophys. Res. Commun.,2004, 313, 212-6.
107. Quigg, R.J.; Alexander, J.J.; Lo, C.F.; Lim, A.; He, C.; Holers, V.M. Characterization of C3-binding proteins on mouse neutrophils and platelets. J. Immunol., 1997, 159, 2438-44.
108. Oike, Y.; Yasunaga, K.; Ito, Y.; Matsumoto, S.; Maekawa, H.; Morisada, T.; Arai, F.; Nakagata, N.; Takeya, M.; Masuho, Y.; Suda, T. Angiopoietin-related growth factor (AGF) promotes epidermal proliferation, remodeling, and regeneration. Proc. Natl. Acad. Sci. U SA., 2003, 100, 9494-9.
109. Martyre, M.C.; Le Bousse-Kerdiles, M.C.; Romquin, N.; Chevillard, S.; Praloran, V.; Demory, J.L.; Dupriez, B. Elevated levels of basic fibroblast growth factor in megakaryocytes and platelets from patients with idiopathic myelofibrosis. Br. J. Haematol., 1997, 97, 441-8.
110. Sipe, J.B.; Zhang, J.; Waits, C.; Skikne, B.; Garimella, R.; Anderson, H.C. Localization of bone morphogenetic proteins (BMPs)-2, -4, and -6 within megakaryocytes and platelets. Bone, 2004, 35, 1316-22.
111. Higashihara, M.; Takahata, K.; Yatomi, Y.; Nakahara, K.; Kurokawa, K. Purification and partial characterization of CD9 antigen of human platelets. FEBS Lett., 1990, 264, 270-4.
112. Philippeaux, M.M.; Vesin, C.; Tacchini-Cottier, F.; Piguet, P.F. Activated human platelets express beta2 integrin. Eur. J. Haematol., 1996, 56, 130-7.
113. Bugert, P.; Dugrillon, A.; Gunaydin, A.; Eichler, H.; Kluter, H. Messenger RNA profiling of human platelets by microarray hybridization. Thromb. Haemost., 2003, 90, 738-48.
114. Quigg, R.J.; Holers, V.M. Characterization of rat complement receptors and regulatory proteins. CR2 and Crry are conserved, and the C3b receptor of neutrophils and platelets is distinct from CR1. J. Immunol., 1995, 155, 1481-8.
115. Guo, J.; Piguet, P.F. Stimulation of thrombocytopoiesis decreases platelet beta2 but not beta1 or beta3 integrins. Br. J. Haematol., 1998, 100, 712-9.
116. Cramer, E.M.; Berger, G.; Berndt, M.C. Platelet alpha-granule and plasma membrane share two new components: CD9 and PECAM-1. Blood, 1994, 84, 1722-30.
117. Cooling, L.L.; Zhang, D.S.; Walker, K.E.; Koerner, T.A. Detection in human blood platelets of sialyl Lewis X gangliosides, potential ligands for CD62 and other selectins. Glycobiology, 1995, 5, 571-81.
118. King, M.; McDermott, P.; Schreiber, A.D. Characterization of the Fc gamma receptor on human platelets. Cell Immunol., 1990, 128, 462-79.
119. Danese, S.; Katz, J.A.; Saibeni, S.; Papa, A.; Gasbarrini, A.; Vecchi, M.; Fiocchi, C. Activated platelets are the source of elevated levels of soluble CD40 ligand in the circulation of inflammatory bowel disease patients. Gut, 2003, 52, 1435-41.
120. Fan, Y.; Ge, Y.; Zhu, H.; Wang, Y.; Yang, B.; Zhuang, Y.; Ma, H.; Zhang, X. Characterization and application of two novel monoclonal antibodies against CD40L: epitope and functional studies on cell membrane CD40L and studies on the origin of soluble serum CD40L. Tissue Antigens, 2004, 64, 257-63.
121. Lewandowska, K.; Kaplan, D.; Husel, W. CD34 expression on platelets. Platelets, 2003, 14, 83-7.
122. Kawabata, K.; Nagake, Y.; Shikata, K.; Fukuda, S.; Nakazono, H.; Takahashi, M.; Ichikawa, H.; Makino, H. Soluble P-selectin is released from activated platelets in vivo during hemodialysis. Nephron, 1998, 78, 148-55.
123. Berger, G.; Masse, J.M.; Cramer, E.M. Alpha-granule membrane mirrors the platelet plasma membrane and contains the glycoproteins Ib, IX, and V. Blood, 1996, 87, 1385-95.
124. Cicha, I.; Garlichs, C.D.; Daniel, W.G.; Goppelt-Struebe, M. Activated human platelets release connective tissue growth factor. Thromb. Haemost., 2004, 91, 755-60.
125. Ramaschi, G.; Torti, M.; Festetics, E.T.; Sinigaglia, F.; Malavasi, F.; Balduini, C. Expression of cyclic ADP-ribose-synthetizing CD38 molecule on human platelet membrane. Blood, 1996, 87, 2308-13.
126. Koziak, K.; Sevigny, J.; Robson, S.C.; Siegel, J.B.; Kaczmarek, E. Analysis of CD39/ATP diphosphohydrolase (ATPDase) expression in endothelial cells, platelets and leukocytes. Thromb. Haemost., 1999, 82, 1538-44.
127. Broekman, M.J.; Handin, R.I.; Cohen, P. Distribution of fibrinogen, and platelet factors 4 and XIII in subcellular fractions of human platelets. Br. J. Haematol., 1975, 31, 51-5.
128. Power, C.A.; Furness, R.B.; Brawand, C.; Wells, T.N. Cloning of a full-length cDNA encoding the neutrophil-activating peptide ENA-78 from human platelets. Gene, 1994, 151, 333-4.
129. Henn, V.; Slupsky, J.R.; Grafe, M.; Anagnostopoulos, I.; Forster, R.; Muller-Berghaus, G.; Kroczek, R.A. CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells. Nature, 1998, 391, 591-4.
130. Henn, V.; Steinbach, S.; Buchner, K.; Presek, P.; Kroczek, R.A. The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. Blood, 2001, 98, 1047-54.
131. Piccardoni, P.; Evangelista, V.; Piccoli, A.; de Gaetano, G.; Walz, A.; Cerletti, C. Thrombin-activated human platelets release two NAP-2 variants that stimulate polymorphonuclear leukocytes. Thromb. Haemost., 1996, 76, 780-5.
132. Avenarius, H.J.; Freund, M.; Kleine, H.D.; Heussner, P.; Poliwoda, H. Granulocyte colony-stimulating factor enhances the expression of CD62 on platelets in vivo. Int. J. Hematol., 1993, 58, 189-96.
133. Ben-Ezra, J.; Sheibani, K.; Hwang, D.L.; Lev-Ran, A. Megakaryocyte synthesis is the source of epidermal growth factor in human platelets. Am. J. Pathol., 1990, 137, 755-9.
134. Erlandsen, S.L.; Greet Bittermann, A.; White, J.; Leith, A.; Marko, M. High-resolution CryoFESEM of individual cell adhesion molecules (CAMs) in the glycocalyx of human platelets: detection of P-selectin (CD62P), GPI-IX complex (CD42A/CD42B alpha, B beta), and integrin GPIIbIIIa (CD41/CD61) by immunogold labeling and stereo imaging. J. Histochem. Cytochem., 2001, 49, 809-19.
135. Ishimoto, Y.; Nakano, T. Release of a product of growth arrestspecific gene 6 from rat platelets. FEBS Lett., 2000, 466, 197-9.
136. Hawrylowicz, C.M.; Santoro, S.A.; Platt, F.M.; Unanue, E.R. Activated platelets express IL-1 activity. J. Immunol., 1989, 143, 4015-8.
137. Park, W.S.; Chae, J.S.; Jung, K.C.; Choi, W.J.; Kook, M.C.; Bae, Y. Production and the characterization of monoclonal antibody against CD43, K06. Tissue Antigens, 2004, 63, 46-53.
138. Sedlmayr, P.; Blaschitz, A.; Wilders-Truschnig, M.; Tiran, A.; Dohr, G. Platelets contain interleukin-1 alpha and beta which are detectable on the cell surface after activation. Scand. J. Immunol., 1995, 42, 209-14.
139. Diacovo, T.G.; deFougerolles, A.R.; Bainton, D.F.; Springer, T.A. A functional integrin ligand on the surface of platelets: intercellular adhesion molecule-2. J. Clin. Invest., 1994, 94, 1243-51.
140. McKenzie, M.E.; Malinin, A.I.; Bell, C.R.; Dzhanashvili, A.; Horowitz, E.D.; Oshrine, B.R.; Atar, D.; Serebruany, V.L. Aspirin inhibits surface glycoprotein IIb/IIIa, P-selectin, CD63, and CD107a receptor expression on human platelets. Blood Coagul. Fibrinolysis, 2003, 14, 249-53.
141. Soslau, G.; Morgan, D.A.; Jaffe, J.S.; Brodsky, I.; Wang, Y. Cytokine mRNA expression in human platelets and a megakaryocytic cell line and cytokine modulation of platelet function. Cytokine, 1997, 9, 405-11.
142. Breimo, E.S.; Osterud, B. Studies of biological functions in blood cells from individuals with large platelets. Platelets, 2003, 14, 413-9.
143. Maciejewski, J.P.; Young, N.S.; Yu, M.; Anderson, S.M.; Sloand, E.M. Analysis of the expression of glycosylphosphatidylinositol anchored proteins on platelets from patients with paroxysmal nocturnal hemoglobinuria. Thromb. Res., 1996, 83, 433-47.
144. Barradas, M.A.; Jagroop, I.A.; Mikhailidis, D.P. Naftidrofuryl inhibits the release of 5-hydroxytryptamine and platelet-derived growth factor from human platelets. Clin. Chim. Acta., 1994, 230, 157-67.
145. Baltus, T.; von Hundelshausen, P.; Mause, S.F.; Buhre, W.; Rossaint, R.; Weber, C. Differential and additive effects of plateletderived chemokines on monocyte arrest on inflamed endothelium under flow conditions. J. Leukoc. Biol., 2005, 78, 435-41.
146. Martini, F.; Riondino, S.; Pignatelli, P.; Gazzaniga, P.P.; Ferroni, P.; Lenti, L. Involvement of GD3 in platelet activation. A novel association with Fcgamma receptor. Biochim. Biophys. Acta., 2002, 1583, 297-304.
147. Okada, F.; Yamaguchi, K.; Ichihara, A.; Nakamura, T. One of two subunits of masking protein in latent TGF-beta is a part of pro- TGF-beta. FEBS Lett., 1989, 242, 240-4.
148. Fava, R.A.; Casey, T.T.; Wilcox, J.; Pelton, R.W.; Moses, H.L.; Nanney, L.B. Synthesis of transforming growth factor-beta 1 by megakaryocytes and its localization to megakaryocyte and platelet alpha-granules. Blood, 1990, 76, 1946-55.
149. Todoroki, N.; Watanabe, Y.; Akaike, T.; Katagiri, Y.; Tanoue, K.; Yamazaki, H.; Tsuji, T.; Toyoshima, S.; Osawa, T. Enhancement by IL-1 beta and IFN-gamma of platelet activation: adhesion to leukocytes via GMP-140/PADGEM protein (CD62). Biochem. Biophys. Res. Commun., 1991, 179, 756-61.
150. Banks, R.E.; Forbes, M.A.; Kinsey, S.E.; Stanley, A.; Ingham, E.; Walters, C.; Selby, P.J. Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology. Br. J. Cancer, 1998, 77, 956-64.
151. Leytin, V.; Allen, D.J.; Gwozdz, A.; Garvey, B.; Freedman, J. Role of platelet surface glycoprotein Ibalpha and P-selectin in the clearance of transfused platelet concentrates. Transfusion, 2004, 44, 1487-95.
152. Mohle, R.; Green, D.; Moore, M.A.; Nachman, R.L.; Rafii, S. Constitutive production and thrombin-induced release of vascular endothelial growth factor by human megakaryocytes and platelets. Proc. Natl. Acad. Sci. USA, 1997, 94, 663-8.
153. Nishibori, M.; Cham, B.; McNicol, A.; Shalev, A.; Jain, N.; Gerrard, J.M. The protein CD63 is in platelet dense granules, is deficient in a patient with Hermansky-Pudlak syndrome, and appears identical to granulophysin. J. Clin. Invest., 1993, 91, 1775-82.
154. Testi, R.; Pulcinelli, F.; Frati, L.; Gazzaniga, P.P.; Santoni, A. CD69 is expressed on platelets and mediates platelet activation and aggregation. J. Exp. Med., 1990, 172, 701-7.
155. Krause, S.W.; Rehli, M.; Heinz, S.; Ebner, R.; Andreesen, R. Characterization of MAX.3 antigen, a glycoprotein expressed on mature macrophages, dendritic cells and blood platelets: identity with CD84. Biochem. J., 2000, 346 Pt 3, 729-36.
156. Wartiovaara, U.; Salven, P.; Mikkola, H.; Lassila, R.; Kaukonen, J.; Joukov, V.; Orpana, A.; Ristimaki, A.; Heikinheimo, M.; Joensuu, H.; Alitalo, K.; Palotie, A. Peripheral blood platelets express VEGF-C and VEGF which are released during platelet activation. Thromb. Haemost., 1998, 80, 171-5.
157. Nepomuceno, R.R.; Tenner, A.J. C1qRP, the C1q receptor that enhances phagocytosis, is detected specifically in human cells of myeloid lineage, endothelial cells, and platelets. J. Immunol., 1998, 160, 1929-35.
158. Kelton, J.G.; Smith, J.W.; Horsewood, P.; Warner, M.N.; Warkentin, T.E.; Finberg, R.W.; Hayward, C.P. ABH antigens on human platelets: expression on the glycosyl phosphatidylinositolanchored protein CD109. J. Lab. Clin. Med., 1998, 132, 142-8.
159. Fitter, S.; Tetaz, T.J.; Berndt, M.C.; Ashman, L.K. Molecular cloning of cDNA encoding a novel platelet-endothelial cell tetraspan antigen, PETA-3. Blood., 1995, 86, 1348-55.
160. Frenette, P.S.; Denis, C.V.; Weiss, L.; Jurk, K.; Subbarao, S.; Kehrel, B.; Hartwig, J.H.; Vestweber, D.; Wagner, D.D. P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo. J. Exp. Med., 2000, 191, 1413-22.
161. Scott, J.L.; Dunn, S.M.; Jin, B.; Hillam, A.J.; Walton, S.; Berndt, M.C.; Murray, A.W.; Krissansen, G.W.; Burns, G.F. Characterization of a novel membrane glycoprotein involved in platelet activation. J. Biol. Chem., 1989, 264, 13475-82.
162. Motani, A.S.; Anggard, E.E.; Ferns, G.A. Recombinant insulin-like growth factor-1 modulates aggregation in human platelets via extracellular calcium. Life Sci., 1996, 58, PL269-74.
163. Cook, P.P.; Chen, J.; Ways, D.K. Interleukin-3 induces translocation and down-regulation of protein kinase C in human platelets. Biochem. Biophys. Res. Commun., 1992, 185, 670-5.
164. Schaufelberger, H.D.; Uhr, M.R.; McGuckin, C.; Logan, R.P.; Misiewicz, J.J.; Gordon-Smith, E.C.; Beglinger, C. Platelets in ulcerative colitis and Crohn's disease express functional interleukin-1 and interleukin-8 receptors. Eur. J. Clin. Invest., 1994, 24, 656-63.
165. Gecse, A.; Kis, B.; Mezei, Z.; Telegdy, G. The effect of bradykinin and substance P on the arachidonate cascade of platelets. Immunopharmacology, 1996, 33, 167-70.
166. Rasmussen, U.B.; Gachet, C.; Schlesinger, Y.; Hanau, D.; Ohlmann, P.; Van Obberghen-Schilling, E.; Pouyssegur, J.; Cazenave, J.P.; Pavirani, A. A peptide ligand of the human thrombin receptor antagonizes alpha-thrombin and partially activates platelets. J. Biol. Chem., 1993, 268, 14322-8.
167. Crist, S.A.; Elzey, B.D.; Ludwig, A.T.; Griffith, T.S.; Staack, J.B.; Lentz, S.R.; Ratliff, T.L. Expression of TNF-related apoptosisinducing ligand (TRAIL) in megakaryocytes and platelets. Exp. Hematol., 2004, 32, 1073-81.
168. Asch, E.; Podack, E. Vitronectin binds to activated human platelets and plays a role in platelet aggregation. J. Clin. Invest., 1990, 85, 1372-8.