Elevated levels of basic fibroblast growth factor in megakaryocytes and platelets from patients with idiopathic myelofibrosis

British Journal of Haematology

Volumn 97, Issue 2, 1997, Pages 441-448

  Martyre M C ^a,c   Le Bousse Kerdiles, M C ^a,b   Romquin, N ^a   Chevillard, S ^c   Praloran, V ^a,d   Demory, J L ^a,e   Dupriez, B ^a,e,f  

^a INSERM   (France)

^b HÔPITAL PAUL BROUSSE   (France)

^c INSTITUT CURIE   (France)

^d LIMOGES UNIVERSITY HOSPITAL   (France)

^e LILLE UNIVERSITY HOSPITAL   (France)

^f Centre Hospitalier de LENS   (France)

Author keywords

bFGF; idiopathic myelofibrosis; megakaryocytes; platelets

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; FEMALE; HEMATOPOIESIS; HUMAN; HUMAN CELL; MALE; MEGAKARYOCYTE; MYELOFIBROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; THROMBOCYTE;

EID: 0031010071     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1997.292671.x     Document Type: Article

References (33)

1. Avraham, H., Banu, N., Scadden, D.T., Abraham, J. & Groopman, J.E. (1994) Modulation of megakaryocytopoiesis by human basic fibroblast growth factor. Blood, 83, 2126-2132.
2. Brunner, G., Nguyen, H., Gabrilove, J., Rifkin, D.B. & Wilson, E.L. (1993) Basic fibroblast growth factor expression in human bone marrow and peripheral blood cells. Blood, 81, 631-638.
3. Bruno, E., Cooper, R.J., Wilson, E.L., Gabrilove, J.L. & Hoffman, R. (1993) Basic fibroblast growth factor promotes the proliferation of human megakaryocyte progenitor cells. Blood, 82, 430-435.
4. Burkhardt, R., Bartl, R., Beil, E., Demmler, K., Hoffman, E. & Kronseder, A. (1974) Myelofibrosis-osteomyelosclerosis syndrome: review of literature in histomorphology. Advances in the Biosciences; Dahlem Workhop on Myelofibrosis-Osteomyelosclerosis Syndrome, Berlin, pp. 9-54.
5. Buschle, M., Janssen, J.W.G., Drexler, H., Lyons, J., Anger, B. & Bartram, C.R. (1988) Evidence for pluripotent stem cell origin of idiopathic myelofibrosis: clonal analysis of a case characterized by a N-ras gene mutation. Leukemia, ii, 658-660.
6. Castro-Malaspina, H., Gay, R.E. & Thanwar, S.L. (1982) Characteristics of bone marrow fibroblast colony forming cells and their progeny in patients with myeloproliferative disorders. Blood, 59, 1046-1056.
7. Castro-Malaspina, H., Rabellino, E.M., Yen, A., Nachman, R.L. & Moore, M.A.S. (1981) Human megakaryocyte stimulation of proliferation of bone marrow fibroblasts. Blood, 57, 781-787.
8. Chomezynsky, P. & Sacchi, N. (1987) Single step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry, 162, 156-159.
9. Dalley, A., Smith, J.M., Reilly, J.T. & MacNeil, S. (1996) Investigation of calmodulin and basic fibroblast growth factor (bFGF) in idiopathic myelofibrosis: evidence for a role of extracellular calmodulin in fibroblast proliferation. British Journal of Haematology, 93, 856-862.
10. Folkman, J. & Klagsbrun, M. (1987) Angiogenic factors. Science, 235, 442-447.
11. Gabbianelli, M., Sargiacomo, M., Pelosi, E., Testa, U., Isacchi, G. & Peschle, C. (1990) 'Pure' human hematopoietic progenitors: permissive action of basic fibroblast growth factor. Science, 249, 1561-1564.
12. Gospodarowicz, D., Schweigerer, L. & Neufeld, G. (1987) Stuctural characterization and biological functions of fibroblasts growth factor. Endocrinology Reviews, 8, 95-114.
13. Han, Z.C., Bellucci, S., Wan, H.Y. & Caen, J.P. (1992) New insights into the regulation of megakaryocytopoiesis by haemopoietic and fibroblastic growth factors and transforming growth factor beta-1. British Journal of Haematology, 81, 1-5.
14. Hibbin, J.A.A., Njoku, O.S., Matutes, E., Lewis, S.M. & Goldman, J.M. (1984) Myeloid progenitor cells in the circulation of patients with myelofibrosis and other myeloproliferative disorders. British Journal of Haematology, 57, 495-503.
15. Jacobson, R.J., Salo, A. & Fialkow, P.J. (1978) Agnogenic myeloid metaplasia: a clonal proliferation of hematopoietic stem cells with secondary myelofibrosis. Blood, 51, 189-194.
16. Klagsbrun, M. (1989) The fibroblast growth factor family: structural and biological properties. Progress in Growth Factor Research, 1, 207-235.
17. Kreipe, H., Jaquet, K., Felgner, J., Radzun, H.J. & Parwaresch, M.R. (1991) Clonal granulocytes and bone marrow cells in the cellular phase of agnogenic myeloid metaplasia. Blood, 78, 1814-1817.
18. Lazlo, J. (1975) Myeloproliferative myelosclerosis, extramedullary hematopoiesis, undifferentiated MPD and hemorrhagic thrombocythemia. Seminars in Hematology, 12, 409-432.
19. Martyré, M.C. (1995) TGF-β and megakaryocytes in the pathogenesis of myelofibrosis in myeloproliferative disorders. Leukemia and Lymphoma, 20, 39-44.
20. Martyré, M.C., Magdelenat, H., Bryckaert, M.C., Laine-Bidron, C. & Calvo, F. (1991) Increased intraplatelet levels of platelet-derived growth factor and transforming growth factor factor-β in patients with myelofibrosis and myeloid metaplasia. British Journal of Haematology 77, 80-86.
21. Martyré, M.C., Romquin, N., Le Bousse-Kerdilès, M.C., Chevillard, S., Benyahia, B., Dupriez, B., Demory, J.L. & Bauters, F. (1994) Transforming growth factor-β and megakaryocytes in the pathogenesis of idiopathic myelofibrosis. British Journal of Haematology, 88, 9-16.
22. Menzel, T., Rahman, Z., Calleja, E., White, K., Wilson, E.L., Wieder, R. & Gabrilove, J. (1996) Elevated intracellular level of basic fibroblast growth factor correlates with stage of chronic lymphocytic leukemia and is associated with resistance to fludarabine. Blood, 87, 1056-1063.
23. Mignatti, P. & Rifkin, D.B. (1991) Release of basic fibroblast growth factor, an angiogenic factor devoid of secretory signal sequence: a trivial phenomenon or a novel secretion mechanism? Journal of Cell Biochemistry, 47, 201-207.
24. Moscatelli, D. (1988) Metabolism of receptor-bound and matrix-bound basic fibroblast growth factor by bovine capillary endothelial cells. Journal of Cell Biology, 107, 753-759.
25. Oliver, L.J., Rifkin, D.B., Gabrilove, J., Hannocks, M.J. & Wilson, E.L. (1990) Long-term culture of human bone marrow stromal cells in the presence of basic fibroblast growth factor. Growth Factors, 3, 231-236.
26. Reilly, J.T., Barnett, D., Dolan, G., Forrest, P., Eastham, J. & Smith, A. (1993) Characterization of an acute micromegakaryocytic leukemia: evidence for the pathogenesis of myelofibrosis. British Journal of Haematology, 83, 58-62.
27. + RNA. Biochemical and Biophysical Research Communiations, 160, 705-710.
28. Rubartelli, A., Cozzolino, F., Talio, M. & Sitia, R. (1990) A novel secretory pathway for interleukin-1β, a protein lacking a signal sequence. EMBO Journal, 9, 1503-1510.
29. Thiele, J., Kuemmel, T., Sander, C. & Fisher, R. (1991) Ultrastructure of the bone marrow tissue in so-called primary (idiopathic) myelofibrosis-osteomyelosclerosis (agnogenic myeloid metaplasia). I. Abnormalities of megakaryopoiesis and thrombocytes. Journal of Submicroscopic Cytology and Pathology, 23, 93-107.
30. Tucker, R.F., Shipley, G.D., Moses, H.L. & Holley, R.W. (1984) Growth inhibitor from BSC-1 cells closely related to platelet type b transforming growth factor. Science, 226, 705-707.
31. Wang, J.C., Lang, H.D., Lichter, S., Weinstein, M. & Benn, P. (1992) Cytogenetic studies of bone marrow fibroblasts cultured from patients with myelofibrosis and myeloid metaplasia. British Journal of Haematology, 80, 184-188.
32. Ward, H.P. & Block, M.H. (1971) The natural history of agnogenic myeloid metaplasia (AMM) and a critical evaluation of its relationship with myeloproliferative syndrome. Medicine (Baltimore), 50, 357-420.
33. Zauli, G., Visani, G., Catani, L., Vianelli, N., Gugliotta, L. & Capitani, S. (1993) Reduced responsiveness of bone marrow megakaryocytes progenitors to platelet-derived transforming growth factor β1, produced in normal amounts, in patients with essential thrombocythaemia. British Journal of Haematology, 83, 14-20.