Sphingosine-1-phosphate activates the AKT pathway to protect small intestines from radiation-induced endothelial apoptosis

Cancer Research

Volumn 70, Issue 23, 2010, Pages 9905-9915

  Bonnaud, Stéphanie ^a   Niaudet, Colin ^a   Legoux, François ^a   Corre, Isabelle ^a   Delpon, Gregory ^b   Saulquin, Xavier ^a   Fuks, Zvi ^c   Gaugler, Marie Hélène ^a,d   Kolesnick, Richard ^c   Paris, François ^a,b  

^a Team 12   (France)

^b CENTRE RENÉ GAUDUCHEAU   (France)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^d INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE IRSN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PERTUSSIS TOXIN; PROTEIN KINASE B; SPHINGOSINE 1 PHOSPHATE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL PROTECTION; CELL TYPE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENDOTHELIUM INJURY; GASTROINTESTINAL DISEASE; IN VITRO STUDY; IN VIVO STUDY; INTESTINE CELL; INTESTINE EPITHELIUM CELL; IRRADIATION; MALE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; RADIATION DOSE; RADIATION ENTEROPATHY; RADIATION PROTECTION; SIGNAL TRANSDUCTION; SMALL INTESTINE; T LYMPHOCYTE;

EID: 78649914463     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-10-2043     Document Type: Article

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