-
1
-
-
0025641727
-
Stem cells: Attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt
-
CS Potten M Loeffler 1990 Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Lessons for and from the crypt Development 110 1001 1020
-
(1990)
Development
, vol.110
, pp. 1001-1020
-
-
Potten, C.S.1
Loeffler, M.2
-
2
-
-
0030895235
-
Regulation and significance of apoptosis in the stem cells of the gastrointestinal epithelium
-
CS Potten JW Wilson C Booth 1997 Regulation and significance of apoptosis in the stem cells of the gastrointestinal epithelium Stem Cells 15 82 93
-
(1997)
Stem Cells
, vol.15
, pp. 82-93
-
-
Potten, C.S.1
Wilson, J.W.2
Booth, C.3
-
3
-
-
0028589378
-
Regulation of cell number in the mammalian gastrointestinal tract: The importance of apoptosis
-
Pt 12
-
PA Hall PJ Coates B Ansari D Hopwood 1994 Regulation of cell number in the mammalian gastrointestinal tract: the importance of apoptosis J Cell Sci 107 Pt 12 3569 3577
-
(1994)
J Cell Sci
, vol.107
, pp. 3569-3577
-
-
Hall, P.A.1
Coates, P.J.2
Ansari, B.3
Hopwood, D.4
-
4
-
-
0038218405
-
Sphingosine-1-phosphate: An enigmatic signalling lipid
-
10.1038/nrm1103
-
S Spiegel S Milstien 2003 Sphingosine-1-phosphate: an enigmatic signalling lipid Nat Rev Mol Cell Biol 4 397 407 10.1038/nrm1103
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 397-407
-
-
Spiegel, S.1
Milstien, S.2
-
5
-
-
0037203316
-
Sphingosine in apoptosis signaling
-
O Cuvillier 2002 Sphingosine in apoptosis signaling Biochim Biophys Acta 1585 153 162
-
(2002)
Biochim Biophys Acta
, vol.1585
, pp. 153-162
-
-
Cuvillier, O.1
-
6
-
-
23844519961
-
Role of sphingosine kinase 2 in cell migration toward epidermal growth factor
-
10.1074/jbc.M502922200
-
NC Hait S Sarkar H Le Stunff A Mikami M Maceyka S Milstien 2005 Role of sphingosine kinase 2 in cell migration toward epidermal growth factor J Biol Chem 280 29462 29469 10.1074/jbc.M502922200
-
(2005)
J Biol Chem
, vol.280
, pp. 29462-29469
-
-
Hait, N.C.1
Sarkar, S.2
Le Stunff, H.3
Mikami, A.4
MacEyka, M.5
Milstien, S.6
-
7
-
-
16644394172
-
Endothelial cell barrier regulation by sphingosine 1-phosphate
-
10.1002/jcb.20088
-
BJ McVerry JG Garcia 2004 Endothelial cell barrier regulation by sphingosine 1-phosphate J Cell Biochem 92 1075 1085 10.1002/jcb.20088
-
(2004)
J Cell Biochem
, vol.92
, pp. 1075-1085
-
-
McVerry, B.J.1
Garcia, J.G.2
-
8
-
-
0036547908
-
Sphingosine-1-phosphate stimulates human caco-2 intestinal epithelial proliferation via p38 activation and activates erk by an independent mechanism
-
10.1290/1071-2690(2002)038≤0246:SPSHCI≥2.0.CO;2
-
V Thamilselvan W Li BE Sumpio MD Basson 2002 Sphingosine-1-phosphate stimulates human caco-2 intestinal epithelial proliferation via p38 activation and activates erk by an independent mechanism In Vitro Cell Dev Biol Anim 38 246 253 10.1290/1071-2690(2002)038≤0246:SPSHCI≥2.0.CO;2
-
(2002)
In Vitro Cell Dev Biol Anim
, vol.38
, pp. 246-253
-
-
Thamilselvan, V.1
Li, W.2
Sumpio, B.E.3
Basson, M.D.4
-
9
-
-
0031042001
-
Distribution of sphingosine 1-phosphate, a bioactive sphingolipid, in rat tissues
-
10.1016/S0014-5793(97)00121-X
-
Y Yatomi RJ Welch Y Igarashi 1997 Distribution of sphingosine 1-phosphate, a bioactive sphingolipid, in rat tissues FEBS Lett 404 173 174 10.1016/S0014-5793(97)00121-X
-
(1997)
FEBS Lett
, vol.404
, pp. 173-174
-
-
Yatomi, Y.1
Welch, R.J.2
Igarashi, Y.3
-
10
-
-
33749185077
-
Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation
-
10.1128/MCB.02341-05
-
M Kohno M Momoi ML Oo JH Paik YM Lee K Venkataraman 2006 Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation Mol Cell Biol 26 7211 23 10.1128/MCB.02341-05
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7211-23
-
-
Kohno, M.1
Momoi, M.2
Oo, M.L.3
Paik, J.H.4
Lee, Y.M.5
Venkataraman, K.6
-
11
-
-
0037203305
-
Sphingosine kinase, sphingosine-1-phosphate, and apoptosis
-
M Maceyka SG Payne S Milstien S Spiegel 2002 Sphingosine kinase, sphingosine-1-phosphate, and apoptosis Biochim Biophys Acta 1585 193 201
-
(2002)
Biochim Biophys Acta
, vol.1585
, pp. 193-201
-
-
MacEyka, M.1
Payne, S.G.2
Milstien, S.3
Spiegel, S.4
-
13
-
-
0023943251
-
Regulation of gastrointestinal mucosal growth
-
LR Johnson 1988 Regulation of gastrointestinal mucosal growth Physiol Rev 68 456 502
-
(1988)
Physiol Rev
, vol.68
, pp. 456-502
-
-
Johnson, L.R.1
-
14
-
-
0035499454
-
Ten years of protein kinase b signalling: A hard akt to follow
-
10.1016/S0968-0004(01)01958-2
-
DP Brazil BA Hemmings 2001 Ten years of protein kinase b signalling: a hard akt to follow Trends Biochem Sci 26 657 664 10.1016/S0968-0004(01)01958-2
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 657-664
-
-
Brazil, D.P.1
Hemmings, B.A.2
-
15
-
-
2542451727
-
Akt kinase activation blocks apoptosis in intestinal epithelial cells by inhibiting caspase-3 after polyamine depletion
-
10.1074/jbc.M314337200
-
HM Zhang JN Rao X Guo L Liu T Zou DJ Turner 2004 Akt kinase activation blocks apoptosis in intestinal epithelial cells by inhibiting caspase-3 after polyamine depletion J Biol Chem 279 22539 22547 10.1074/jbc.M314337200
-
(2004)
J Biol Chem
, vol.279
, pp. 22539-22547
-
-
Zhang, H.M.1
Rao, J.N.2
Guo, X.3
Liu, L.4
Zou, T.5
Turner, D.J.6
-
16
-
-
0037183989
-
Regulation of trail expression by the phosphatidylinositol 3-kinase/akt/gsk-3 pathway in human colon cancer cells
-
10.1074/jbc.M206306200
-
Q Wang X Wang A Hernandez MR Hellmich Z Gatalica BM Evers 2002 Regulation of trail expression by the phosphatidylinositol 3-kinase/akt/gsk-3 pathway in human colon cancer cells J Biol Chem 277 36602 36610 10.1074/jbc.M206306200
-
(2002)
J Biol Chem
, vol.277
, pp. 36602-36610
-
-
Wang, Q.1
Wang, X.2
Hernandez, A.3
Hellmich, M.R.4
Gatalica, Z.5
Evers, B.M.6
-
17
-
-
0037404666
-
Abeta42 generation is toxic to endothelial cells and inhibits enos function through an akt/gsk-3beta signaling-dependent mechanism
-
10.1016/S0197-4580(02)00135-5
-
T Suhara J Magrane K Rosen R Christensen HS Kim B Zheng 2003 Abeta42 generation is toxic to endothelial cells and inhibits enos function through an akt/gsk-3beta signaling-dependent mechanism Neurobiol Aging 24 437 451 10.1016/S0197-4580(02)00135-5
-
(2003)
Neurobiol Aging
, vol.24
, pp. 437-451
-
-
Suhara, T.1
Magrane, J.2
Rosen, K.3
Christensen, R.4
Kim, H.S.5
Zheng, B.6
-
18
-
-
0037102157
-
Phosphatidylinositol 3-kinase/akt signaling in the response of vascular endothelium to ionizing radiation
-
E Edwards L Geng J Tan H Onishko E Donnelly DE Hallahan 2002 Phosphatidylinositol 3-kinase/akt signaling in the response of vascular endothelium to ionizing radiation Cancer Res 62 4671 46777
-
(2002)
Cancer Res
, vol.62
, pp. 4671-46777
-
-
Edwards, E.1
Geng, L.2
Tan, J.3
Onishko, H.4
Donnelly, E.5
Hallahan, D.E.6
-
19
-
-
0031053586
-
Regulation of neuronal survival by the serine-threonine protein kinase akt
-
10.1126/science.275.5300.661
-
H Dudek SR Datta TF Franke MJ Birnbaum R Yao GM Cooper 1997 Regulation of neuronal survival by the serine-threonine protein kinase akt Science 275 661 665 10.1126/science.275.5300.661
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
-
20
-
-
0030907987
-
Pi3k: Downstream aktion blocks apoptosis
-
10.1016/S0092-8674(00)81883-8
-
TF Franke DR Kaplan LC Cantley 1997 Pi3k: downstream aktion blocks apoptosis Cell 88 435 437 10.1016/S0092-8674(00)81883-8
-
(1997)
Cell
, vol.88
, pp. 435-437
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
-
22
-
-
0033582929
-
Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor
-
10.1016/S0092-8674(00)80595-4
-
A Brunet A Bonni MJ Zigmond MZ Lin P Juo LS Hu 1999 Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor Cell 96 857 68 10.1016/S0092-8674(00)80595-4
-
(1999)
Cell
, vol.96
, pp. 857-68
-
-
Brunet, A.1
Bonni, A.2
Zigmond, M.J.3
Lin, M.Z.4
Juo, P.5
Hu, L.S.6
-
23
-
-
0030032310
-
An intestine-specific homeobox gene regulates proliferation and differentiation
-
E Suh PG Traber 1996 An intestine-specific homeobox gene regulates proliferation and differentiation Mol Cell Biol 16 619 625
-
(1996)
Mol Cell Biol
, vol.16
, pp. 619-625
-
-
Suh, E.1
Traber, P.G.2
-
25
-
-
0033385964
-
Differentiated intestinal epithelial cells exhibit increased migration through polyamines and myosin ii
-
JN Rao J Li L Li BL Bass JY Wang 1999 Differentiated intestinal epithelial cells exhibit increased migration through polyamines and myosin ii Am J Physiol 277 G1149 G1158
-
(1999)
Am J Physiol
, vol.277
-
-
Rao, J.N.1
Li, J.2
Li, L.3
Bass, B.L.4
Wang, J.Y.5
-
27
-
-
0018394382
-
Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria
-
10.1083/jcb.80.2.248
-
A Quaroni J Wands RL Trelstad KJ Isselbacher 1979 Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria J Cell Biol 80 248 265 10.1083/jcb.80.2.248
-
(1979)
J Cell Biol
, vol.80
, pp. 248-265
-
-
Quaroni, A.1
Wands, J.2
Trelstad, R.L.3
Isselbacher, K.J.4
-
28
-
-
26444551684
-
Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by s1p1 receptor, pi3 kinase, tiam1/rac1, and alpha-actinin
-
10.1096/fj.05-3928com
-
PA Singleton SM Dudek ET Chiang JG Garcia 2005 Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by s1p1 receptor, pi3 kinase, tiam1/rac1, and alpha-actinin FASEB J 19 1646 1656 10.1096/fj.05-3928com
-
(2005)
FASEB J
, vol.19
, pp. 1646-1656
-
-
Singleton, P.A.1
Dudek, S.M.2
Chiang, E.T.3
Garcia, J.G.4
-
29
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
10.1016/0003-2697(76)90527-3
-
MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 10.1016/0003-2697(76)90527-3
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
30
-
-
0142213140
-
Polyamines are required for activation of c-jun nh2-terminal kinase and apoptosis in response to tnf-alpha in iec-6 cells
-
S Bhattacharya RM Ray MJ Viar LR Johnson 2003 Polyamines are required for activation of c-jun nh2-terminal kinase and apoptosis in response to tnf-alpha in iec-6 cells Am J Physiol Gastrointest Liver Physiol 285 G980 G991
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.285
-
-
Bhattacharya, S.1
Ray, R.M.2
Viar, M.J.3
Johnson, L.R.4
-
31
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4 h-1-benzopyran-4-one (ly294002)
-
CJ Vlahos WF Matter KY Hui RF Brown 1994 A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4 h-1-benzopyran-4-one (ly294002) J Biol Chem 269 5241 5248
-
(1994)
J Biol Chem
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
-
32
-
-
0035026932
-
Nf-kappab activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells
-
L Li JN Rao BL Bass JY Wang 2001 Nf-kappab activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells Am J Physiol Gastrointest Liver Physiol 280 G992 G1004
-
(2001)
Am J Physiol Gastrointest Liver Physiol
, vol.280
-
-
Li, L.1
Rao, J.N.2
Bass, B.L.3
Wang, J.Y.4
-
33
-
-
1942486873
-
Nf-kappab-mediated iap expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion
-
10.1152/ajpcell.00480.2003
-
T Zou JN Rao X Guo L Liu HM Zhang ED Strauch 2004 Nf-kappab-mediated iap expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion Am J Physiol Cell Physiol 286 C1009 C1018 10.1152/ajpcell.00480.2003
-
(2004)
Am J Physiol Cell Physiol
, vol.286
-
-
Zou, T.1
Rao, J.N.2
Guo, X.3
Liu, L.4
Zhang, H.M.5
Strauch, E.D.6
-
34
-
-
0030882522
-
Epithelial cell growth and differentiation. Ii. Intestinal apoptosis
-
CS Potten 1997 Epithelial cell growth and differentiation. Ii. Intestinal apoptosis Am J Physiol 273 G253 G257
-
(1997)
Am J Physiol
, vol.273
-
-
Potten, C.S.1
-
35
-
-
0031408388
-
Physiology and pathophysiology of apoptosis in epithelial cells of the liver, pancreas, and intestine
-
BA Jones GJ Gores 1997 Physiology and pathophysiology of apoptosis in epithelial cells of the liver, pancreas, and intestine Am J Physiol 273 G1174 G1188
-
(1997)
Am J Physiol
, vol.273
-
-
Jones, B.A.1
Gores, G.J.2
-
36
-
-
0000227612
-
Pten/mmac1/tep1 in signal transduction and tumorigenesis
-
10.1046/j.1432-1327.1999.00542.x
-
A Besson SM Robbins VW Yong 1999 Pten/mmac1/tep1 in signal transduction and tumorigenesis Eur J Biochem 263 605 611 10.1046/j.1432-1327.1999.00542.x
-
(1999)
Eur J Biochem
, vol.263
, pp. 605-611
-
-
Besson, A.1
Robbins, S.M.2
Yong, V.W.3
-
37
-
-
0242410157
-
Sphingosine-1-phosphate inhibition of apoptosis requires mitogen-activated protein kinase phosphatase-1 in mouse fibroblast c3h10t 1/2 cells
-
SS Castillo D Teegarden 2003 Sphingosine-1-phosphate inhibition of apoptosis requires mitogen-activated protein kinase phosphatase-1 in mouse fibroblast c3h10t 1/2 cells J Nutr 133 3343 3349
-
(2003)
J Nutr
, vol.133
, pp. 3343-3349
-
-
Castillo, S.S.1
Teegarden, D.2
-
38
-
-
33845291120
-
Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases
-
NC Hait CA Oskeritzian SW Paugh S Milstien S Spiegel 2006 Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases Biochim Biophys Acta 1758 2016 2026
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 2016-2026
-
-
Hait, N.C.1
Oskeritzian, C.A.2
Paugh, S.W.3
Milstien, S.4
Spiegel, S.5
-
39
-
-
33748754785
-
Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells
-
10.1210/en.2006-0456
-
SG Laychock SM Sessanna MH Lin LD Mastrandrea 2006 Sphingosine 1-phosphate affects cytokine-induced apoptosis in rat pancreatic islet beta-cells Endocrinology 147 4705 4712 10.1210/en.2006-0456
-
(2006)
Endocrinology
, vol.147
, pp. 4705-4712
-
-
Laychock, S.G.1
Sessanna, S.M.2
Lin, M.H.3
Mastrandrea, L.D.4
-
40
-
-
24644469502
-
Lymphocyte sequestration through s1p lyase inhibition and disruption of s1p gradients
-
10.1126/science.1113640
-
SR Schwab JP Pereira M Matloubian Y Xu Y Huang JG Cyster 2005 Lymphocyte sequestration through s1p lyase inhibition and disruption of s1p gradients Science 309 1735 1739 10.1126/science.1113640
-
(2005)
Science
, vol.309
, pp. 1735-1739
-
-
Schwab, S.R.1
Pereira, J.P.2
Matloubian, M.3
Xu, Y.4
Huang, Y.5
Cyster, J.G.6
-
41
-
-
33750456153
-
Targeting sphingosine-1-phosphate for cancer therapy
-
10.1038/sj.bjc.6603400
-
RA Sabbadini 2006 Targeting sphingosine-1-phosphate for cancer therapy Br J Cancer 95 1131 1135 10.1038/sj.bjc.6603400
-
(2006)
Br J Cancer
, vol.95
, pp. 1131-1135
-
-
Sabbadini, R.A.1
-
43
-
-
33751225686
-
Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer
-
10.1073/pnas.0600050103
-
B Oskouian P Sooriyakumaran AD Borowsky A Crans L Dillard-Telm YY Tam 2006 Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer Proc Natl Acad Sci USA 103 17384 17389 10.1073/pnas.0600050103
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17384-17389
-
-
Oskouian, B.1
Sooriyakumaran, P.2
Borowsky, A.D.3
Crans, A.4
Dillard-Telm, L.5
Tam, Y.Y.6
-
44
-
-
33646422498
-
Induced focal adhesion kinase expression suppresses apoptosis by activating nf-kappab signaling in intestinal epithelial cells
-
10.1152/ajpcell.00450.2005
-
HM Zhang KM Keledjian JN Rao T Zou L Liu BS Marasa 2006 Induced focal adhesion kinase expression suppresses apoptosis by activating nf-kappab signaling in intestinal epithelial cells Am J Physiol Cell Physiol 290 C1310 C1320 10.1152/ajpcell.00450.2005
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Zhang, H.M.1
Keledjian, K.M.2
Rao, J.N.3
Zou, T.4
Liu, L.5
Marasa, B.S.6
-
45
-
-
0036205587
-
Mechanisms of caspase activation and inhibition during apoptosis
-
10.1016/S1097-2765(02)00482-3
-
Y Shi 2002 Mechanisms of caspase activation and inhibition during apoptosis Mol Cell 9 459 470 10.1016/S1097-2765(02)00482-3
-
(2002)
Mol Cell
, vol.9
, pp. 459-470
-
-
Shi, Y.1
-
46
-
-
0027318112
-
Somatic mutation, monoclonality and stochastic models of stem cell organization in the intestinal crypt
-
10.1006/jtbi.1993.1031
-
M Loeffler A Birke D Winton C Potten 1993 Somatic mutation, monoclonality and stochastic models of stem cell organization in the intestinal crypt J Theor Biol 160 471 491 10.1006/jtbi.1993.1031
-
(1993)
J Theor Biol
, vol.160
, pp. 471-491
-
-
Loeffler, M.1
Birke, A.2
Winton, D.3
Potten, C.4
-
47
-
-
0025882091
-
Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily
-
10.1073/pnas.88.10.4171
-
PF Jones T Jakubowicz FJ Pitossi F Maurer BA Hemmings 1991 Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily Proc Natl Acad Sci USA 88 4171 4175 10.1073/pnas.88.10.4171
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 4171-4175
-
-
Jones, P.F.1
Jakubowicz, T.2
Pitossi, F.J.3
Maurer, F.4
Hemmings, B.A.5
-
48
-
-
0030799706
-
Dual role of phosphatidylinositol-3, 4, 5-trisphosphate in the activation of protein kinase b
-
10.1126/science.277.5325.567
-
D Stokoe LR Stephens T Copeland PR Gaffney CB Reese GF Painter 1997 Dual role of phosphatidylinositol-3, 4, 5-trisphosphate in the activation of protein kinase b Science 277 567 570 10.1126/science.277.5325.567
-
(1997)
Science
, vol.277
, pp. 567-570
-
-
Stokoe, D.1
Stephens, L.R.2
Copeland, T.3
Gaffney, P.R.4
Reese, C.B.5
Painter, G.F.6
-
49
-
-
33847702961
-
Tumor necrosis factor-alpha-stimulated cell proliferation is mediated through sphingosine kinase-dependent akt activation and cyclin d expression
-
10.1074/jbc.M601698200
-
J Radeff-Huang TM Seasholtz JW Chang JM Smith CT Walsh JH Brown 2007 Tumor necrosis factor-alpha-stimulated cell proliferation is mediated through sphingosine kinase-dependent akt activation and cyclin d expression J Biol Chem 282 863 870 10.1074/jbc.M601698200
-
(2007)
J Biol Chem
, vol.282
, pp. 863-870
-
-
Radeff-Huang, J.1
Seasholtz, T.M.2
Chang, J.W.3
Smith, J.M.4
Walsh, C.T.5
Brown, J.H.6
-
50
-
-
2342618936
-
Multiple roles of the pi3k/pkb (akt) pathway in cell cycle progression
-
J Liang JM Slingerland 2003 Multiple roles of the pi3k/pkb (akt) pathway in cell cycle progression Cell Cycle 2 339 345
-
(2003)
Cell Cycle
, vol.2
, pp. 339-345
-
-
Liang, J.1
Slingerland, J.M.2
-
51
-
-
0035949699
-
Akt plays a central role in tumorigenesis
-
10.1073/pnas.211430998
-
JR Testa A Bellacosa 2001 Akt plays a central role in tumorigenesis Proc Natl Acad Sci USA 98 10983 10985 10.1073/pnas.211430998
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10983-10985
-
-
Testa, J.R.1
Bellacosa, A.2
-
52
-
-
0037203546
-
Akt: Versatile mediator of cell survival and beyond
-
D Kim J Chung 2002 Akt: Versatile mediator of cell survival and beyond J Biochem Mol Biol 35 106 115
-
(2002)
J Biochem Mol Biol
, vol.35
, pp. 106-115
-
-
Kim, D.1
Chung, J.2
-
53
-
-
0032533225
-
Glycogen synthase kinase-3beta regulates cyclin d1 proteolysis and subcellular localization
-
10.1101/gad.12.22.3499
-
JA Diehl M Cheng MF Roussel CJ Sherr 1998 Glycogen synthase kinase-3beta regulates cyclin d1 proteolysis and subcellular localization Genes Dev 12 3499 3511 10.1101/gad.12.22.3499
-
(1998)
Genes Dev
, vol.12
, pp. 3499-3511
-
-
Diehl, J.A.1
Cheng, M.2
Roussel, M.F.3
Sherr, C.J.4
-
54
-
-
0034671768
-
Phosphorylation-dependent regulation of cyclin d1 nuclear export and cyclin d1-dependent cellular transformation
-
10.1101/gad.854900
-
JR Alt JL Cleveland M Hannink JA Diehl 2000 Phosphorylation-dependent regulation of cyclin d1 nuclear export and cyclin d1-dependent cellular transformation Genes Dev 14 3102 3114 10.1101/gad.854900
-
(2000)
Genes Dev
, vol.14
, pp. 3102-3114
-
-
Alt, J.R.1
Cleveland, J.L.2
Hannink, M.3
Diehl, J.A.4
-
55
-
-
33645644184
-
Rac1 modulates sphingosine 1-phosphate-mediated activation of phosphoinositide 3-kinase/akt signaling pathways in vascular endothelial cells
-
10.1074/jbc.M510434200
-
E Gonzalez R Kou T Michel 2006 Rac1 modulates sphingosine 1-phosphate-mediated activation of phosphoinositide 3-kinase/akt signaling pathways in vascular endothelial cells J Biol Chem 281 3210 3216 10.1074/jbc.M510434200
-
(2006)
J Biol Chem
, vol.281
, pp. 3210-3216
-
-
Gonzalez, E.1
Kou, R.2
Michel, T.3
-
56
-
-
34948819302
-
Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the pi3k/pkb and mek/erk 1/2 pathways
-
10.1194/jlr.M700291-JLR200
-
L Brizuela M Rabano P Gangoiti N Narbona JM Macarulla M Trueba 2007 Sphingosine-1-phosphate stimulates aldosterone secretion through a mechanism involving the pi3k/pkb and mek/erk 1/2 pathways J Lipid Res 48 2264 2274 10.1194/jlr.M700291-JLR200
-
(2007)
J Lipid Res
, vol.48
, pp. 2264-2274
-
-
Brizuela, L.1
Rabano, M.2
Gangoiti, P.3
Narbona, N.4
MacArulla, J.M.5
Trueba, M.6
-
57
-
-
0034644523
-
Cellular signaling: Pivoting around pdk-1
-
10.1016/S0092-8674(00)00110-0
-
A Toker AC Newton 2000 Cellular signaling: Pivoting around pdk-1 Cell 103 185 188 10.1016/S0092-8674(00)00110-0
-
(2000)
Cell
, vol.103
, pp. 185-188
-
-
Toker, A.1
Newton, A.C.2
-
58
-
-
1842455323
-
Point-counterpoint of sphingosine 1-phosphate metabolism
-
10.1161/01.RES.0000122383.60368.24
-
JD Saba T Hla 2004 Point-counterpoint of sphingosine 1-phosphate metabolism Circ Res 94 724 734 10.1161/01.RES.0000122383.60368.24
-
(2004)
Circ Res
, vol.94
, pp. 724-734
-
-
Saba, J.D.1
Hla, T.2
-
59
-
-
0036436697
-
Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer mcf-7 cells
-
10.1006/excr.2002.5658
-
VE Nava JP Hobson S Murthy S Milstien S Spiegel 2002 Sphingosine kinase type 1 promotes estrogen-dependent tumorigenesis of breast cancer mcf-7 cells Exp Cell Res 281 115 127 10.1006/excr.2002.5658
-
(2002)
Exp Cell Res
, vol.281
, pp. 115-127
-
-
Nava, V.E.1
Hobson, J.P.2
Murthy, S.3
Milstien, S.4
Spiegel, S.5
-
60
-
-
33748178875
-
Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate
-
10.1182/blood-2006-04-014852
-
A Weigert AM Johann A von Knethen H Schmidt G Geisslinger B Brune 2006 Apoptotic cells promote macrophage survival by releasing the antiapoptotic mediator sphingosine-1-phosphate Blood 108 1635 1642 10.1182/blood-2006-04- 014852
-
(2006)
Blood
, vol.108
, pp. 1635-1642
-
-
Weigert, A.1
Johann, A.M.2
Von Knethen, A.3
Schmidt, H.4
Geisslinger, G.5
Brune, B.6
-
61
-
-
0038045489
-
Matrix metalloproteinase regulation of sphingosine-1-phosphate-induced angiogenic properties of bone marrow stromal cells
-
10.1016/S0301-472X(03)00090-0
-
B Annabi S Thibeault YT Lee N Bousquet-Gagnon N Eliopoulos S Barrette 2003 Matrix metalloproteinase regulation of sphingosine-1-phosphate-induced angiogenic properties of bone marrow stromal cells Exp Hematol 31 640 649 10.1016/S0301-472X(03)00090-0
-
(2003)
Exp Hematol
, vol.31
, pp. 640-649
-
-
Annabi, B.1
Thibeault, S.2
Lee, Y.T.3
Bousquet-Gagnon, N.4
Eliopoulos, N.5
Barrette, S.6
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