MAP/ERK Kinase Kinase 1 (MEKK1) mediates transcriptional repression by interacting with Polycystic Kidney Disease-1 (PKD1) promoter-bound p53 tumor suppressor protein

Journal of Biological Chemistry

Volumn 285, Issue 50, 2010, Pages 38818-38831

  Islam, M Rafiq ^a,b   Jimenez, Tamara ^a   Pelham, Christopher ^a   Rodova, Marianna ^b   Puri, Sanjeev ^b   Magenheimer, Brenda S ^b   Maser, Robin L ^c   Widmann, Christian ^d   Calvet, James P ^b  

^a NORTHWEST MISSOURI STATE UNIVERSITY   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^d UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOSOMAL-DOMINANT POLYCYSTIC KIDNEY DISEASE; CELLULAR PROCESS; COREPRESSORS; ELEVATED STRESS; KINASE ACTIVITY; MITOGEN ACTIVATED PROTEIN KINASE; NEW MECHANISMS; POLYCYSTIC KIDNEY DISEASE; TRANSCRIPTIONAL ACTIVITY; TRANSCRIPTIONAL REPRESSION; TUMOR SUPPRESSOR PROTEINS;

PHOSPHORYLATION; PROTEINS; TUMORS;

GENE EXPRESSION;

MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; POLYCYSTIN 1; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE ACTIVITY; GENE EXPRESSION; GENE MUTATION; GENE REPRESSION; GENE TARGETING; GENE TRANSLOCATION; HUMAN; HUMAN CELL; KIDNEY POLYCYSTIC DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DNA INTERACTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; TUMOR SUPPRESSOR GENE;

ANIMALS; BASE SEQUENCE; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MAP KINASE KINASE KINASE 1; MICE; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTAGENESIS; OXIDATIVE STRESS; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC; TRPP CATION CHANNELS; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 78649875479     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.145284     Document Type: Article

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