Loss of the polycystic kidney disease (PKD1) region of chromosome 16p13 in renal cyst cells supports a loss-of-function model for cyst pathogenesis

Journal of Clinical Investigation

Volumn 99, Issue 2, 1997, Pages 194-199

  Brasier, Judy L ^a   Henske, Elizabeth Petri ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b FOX CHASE CANCER CENTER   (United States)

Author keywords

chromosome deletion; chromosomes, human, pair 16; gene deletion; kidney, polycystic, autosomal dominant; tuberous sclerosis

Indexed keywords

CELL DNA;

ARTICLE; AUTORADIOGRAPHY; AUTOSOMAL DOMINANT DISORDER; CASE REPORT; CELL ISOLATION; CHROMOSOME 16P; EPITHELIUM CELL; GENE MUTATION; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; KIDNEY CYST; KIDNEY POLYCYSTIC DISEASE; PATHOGENESIS; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0031035050     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119147     Document Type: Article

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