Alpha-lipoic acid inhibits TNF-α induced NF-κB activation through blocking of MEKK1-MKK4-IKK signaling cascades

International Immunopharmacology

Volumn 8, Issue 2, 2008, Pages 362-370

  Lee, Chang Keun ^a   Lee, Eun Young ^b   Kim, Yong Gil ^a   Mun, Se Hwan ^c   Moon, Hee Bom ^a   Yoo, Bin ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Asan Institute for Life Sciences   (South Korea)

Author keywords

lipoic acid; Mitogen activated protein kinases; NF B; TNF

Indexed keywords

I KAPPA B; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 1; THIOCTIC ACID; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; TUMOR NECROSIS FACTOR ALPHA;

ANTIGEN ANTIBODY COMPLEX; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STIMULATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN TISSUE; IMMUNOPRECIPITATION; PRIORITY JOURNAL; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; SYNOVIOCYTE; WESTERN BLOTTING;

CELLS, CULTURED; HUMANS; I-KAPPA B KINASE; MAP KINASE KINASE 4; MAP KINASE KINASE KINASE 1; NF-KAPPA B; SIGNAL TRANSDUCTION; THIOCTIC ACID; TUMOR NECROSIS FACTOR-ALPHA;

EID: 37549047574     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2007.10.020     Document Type: Article

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