메뉴 건너뛰기




Volumn 54, Issue SUPPL. 2, 2010, Pages

Disposition of hop prenylflavonoids in human breast tissue

Author keywords

17 estradiol; 8 prenylnaringenin; Bioavailability; Breast tissue; Humulus lupulus

Indexed keywords

8 PRENYLNARINGENIN; 8-PRENYLNARINGENIN; FLAVANONE DERIVATIVE; FLAVONOID; ISOXANTHOHUMOL; PHYTOESTROGEN; PROPIOPHENONE DERIVATIVE; XANTHOHUMOL; XANTHONE DERIVATIVE;

EID: 78649867931     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200900519     Document Type: Article
Times cited : (64)

References (64)
  • 1
    • 34547456133 scopus 로고    scopus 로고
    • Editorial - hormonally active compounds in food
    • Metzler, M., Editorial - hormonally active compounds in food. Mol. Nutr. Food Res. 2007, 51, 763.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 763
    • Metzler, M.1
  • 2
    • 35548968814 scopus 로고    scopus 로고
    • Isoflavones as phytoestrogens in food supplements and dietary foods for special medical purposes
    • Eisenbrand, G., Isoflavones as phytoestrogens in food supplements and dietary foods for special medical purposes. Mol. Nutr. Food Res. 2007, 51, 1305-1312.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 1305-1312
    • Eisenbrand, G.1
  • 3
    • 49649109907 scopus 로고    scopus 로고
    • Untitled - Answer to Dr. Messina's letter to the Editor
    • Eisenbrand, G., Untitled - Answer to Dr. Messina's letter to the Editor. Mol. Nutr. Food Res. 2008, 52, 737-738.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 737-738
    • Eisenbrand, G.1
  • 4
    • 41949131156 scopus 로고    scopus 로고
    • Conclusion that isoflavones exert estrogenic effects on breast tissue and may raise breast cancer risk unfounded
    • Messina, M., Conclusion that isoflavones exert estrogenic effects on breast tissue and may raise breast cancer risk unfounded. Mol. Nutr. Food Res. 2008, 52, 299-300.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 299-300
    • Messina, M.1
  • 5
    • 33746036436 scopus 로고    scopus 로고
    • Morphologic changes induced by oral long-term treatment with 8-prenylnaringenin in the uterus, vagina, and mammary gland of castrated rats
    • Rimoldi, G., Christoffel, J., Wuttke, W., Morphologic changes induced by oral long-term treatment with 8-prenylnaringenin in the uterus, vagina, and mammary gland of castrated rats. Menopause 2006, 13, 669-677.
    • (2006) Menopause , vol.13 , pp. 669-677
    • Rimoldi, G.1    Christoffel, J.2    Wuttke, W.3
  • 6
    • 65549120719 scopus 로고    scopus 로고
    • Perspectives on the soy-breast cancer relation
    • Messina, M., Wu, A. H., Perspectives on the soy-breast cancer relation. Am. J. Clin. Nutr. 2009, 89, S1673-S1679.
    • (2009) Am. J. Clin. Nutr. , vol.89
    • Messina, M.1    Wu, A.H.2
  • 7
    • 62849090724 scopus 로고    scopus 로고
    • Isoflavones - mechanism of action and impact on breast cancer risk
    • Stubert, J., Gerber, B., Isoflavones - mechanism of action and impact on breast cancer risk. Breast Care 2009, 4, 22-29.
    • (2009) Breast Care , vol.4 , pp. 22-29
    • Stubert, J.1    Gerber, B.2
  • 8
    • 0033007552 scopus 로고    scopus 로고
    • Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry
    • Stevens, J. F., Taylor, A. W., Deinzer, M. L., Quantitative analysis of xanthohumol and related prenylflavonoids in hops and beer by liquid chromatography-tandem mass spectrometry. J. Chromatogr. A 1999, 832, 97-107.
    • (1999) J. Chromatogr. A , vol.832 , pp. 97-107
    • Stevens, J.F.1    Taylor, A.W.2    Deinzer, M.L.3
  • 9
    • 0034753762 scopus 로고    scopus 로고
    • Identification, quantitation and biological activity of phytoestrogens in a dietary supplement for breast enhancement
    • Coldham, N. G., Sauer, M. J., Identification, quantitation and biological activity of phytoestrogens in a dietary supplement for breast enhancement. Food Chem. Toxicol. 2001, 39, 1211-1224.
    • (2001) Food Chem. Toxicol. , vol.39 , pp. 1211-1224
    • Coldham, N.G.1    Sauer, M.J.2
  • 10
    • 33646128011 scopus 로고    scopus 로고
    • A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts
    • Heyerick, A., Vervarcke, S., Depypere, H., Bracke, M., De Keukeleire, D., A first prospective, randomized, double-blind, placebo-controlled study on the use of a standardized hop extract to alleviate menopausal discomforts. Maturitas 2006, 54, 164-175.
    • (2006) Maturitas , vol.54 , pp. 164-175
    • Heyerick, A.1    Vervarcke, S.2    Depypere, H.3    Bracke, M.4    De Keukeleire, D.5
  • 11
    • 0033304530 scopus 로고    scopus 로고
    • Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer
    • Milligan, S. R., Kalita, J. C., Heyerick, A., Rong, H. et al., Identification of a potent phytoestrogen in hops (Humulus lupulus L.) and beer. J. Clin. Endocrinol. Metab. 1999, 83, 2249-2252.
    • (1999) J. Clin. Endocrinol. Metab. , vol.83 , pp. 2249-2252
    • Milligan, S.R.1    Kalita, J.C.2    Heyerick, A.3    Rong, H.4
  • 12
    • 27744471449 scopus 로고    scopus 로고
    • Tissue specificity of 8-prenylnaringenin: protection from ovariectomy induced bone loss with minimal trophic effects on the uterus
    • Hümpel, M., Isaksson, P., Schaefer, O., Kaufmann, U. et al., Tissue specificity of 8-prenylnaringenin: protection from ovariectomy induced bone loss with minimal trophic effects on the uterus. J. Steroid Biochem. Mol. Biol. 2005, 97, 299-305.
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.97 , pp. 299-305
    • Hümpel, M.1    Isaksson, P.2    Schaefer, O.3    Kaufmann, U.4
  • 13
    • 33745243308 scopus 로고    scopus 로고
    • Identification of human hepatic cytochrome P450 enzymes involved in the metabolism of 8-prenylnaringenin and isoxanthohumol form hops (Humulus lupulus L.)
    • Guo, J., Nikolic, D., Chadwick, L. R., Pauli, G. F., van Breemen, R. B., Identification of human hepatic cytochrome P450 enzymes involved in the metabolism of 8-prenylnaringenin and isoxanthohumol form hops (Humulus lupulus L.). Drug Metab. Dispos. 2006, 34, 1152-1159.
    • (2006) Drug Metab. Dispos. , vol.34 , pp. 1152-1159
    • Guo, J.1    Nikolic, D.2    Chadwick, L.R.3    Pauli, G.F.4    van Breemen, R.B.5
  • 14
    • 15344344829 scopus 로고    scopus 로고
    • Metabolism of xanthohumol and isoxanthohumol, prenylated flavonoids from hops (Humulus lupulus L.), by human liver microsomes
    • Nikolic, D., Li, Y., Chadwick, L. R., Pauli, G., van Breemen, R. B., Metabolism of xanthohumol and isoxanthohumol, prenylated flavonoids from hops (Humulus lupulus L.), by human liver microsomes. J. Mass Spectrom. 2005, 40, 289-299.
    • (2005) J. Mass Spectrom. , vol.40 , pp. 289-299
    • Nikolic, D.1    Li, Y.2    Chadwick, L.R.3    Pauli, G.4    van Breemen, R.B.5
  • 15
    • 35148830351 scopus 로고    scopus 로고
    • Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women
    • Bolca, S., Possemiers, S., Maervoet, V., Huybrechts, I. et al., Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women. Br. J. Nutr. 2007, 98, 950-959.
    • (2007) Br. J. Nutr. , vol.98 , pp. 950-959
    • Bolca, S.1    Possemiers, S.2    Maervoet, V.3    Huybrechts, I.4
  • 16
    • 33745670638 scopus 로고    scopus 로고
    • The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine
    • Possemiers, S., Bolca, S., Grootaert, C., Heyerick, A. et al., The prenylflavonoid isoxanthohumol from hops (Humulus lupulus L.) is activated into the potent phytoestrogen 8-prenylnaringenin in vitro and in the human intestine. J. Nutr. 2006, 136, 1862-1867.
    • (2006) J. Nutr. , vol.136 , pp. 1862-1867
    • Possemiers, S.1    Bolca, S.2    Grootaert, C.3    Heyerick, A.4
  • 18
    • 19044388959 scopus 로고    scopus 로고
    • In vitro biological properties of flavonoid conjugates found in vivo
    • Williamson, G., Barron, D., Shimoi, K., Terao, J., In vitro biological properties of flavonoid conjugates found in vivo. Free Radic. Res. 2005, 39, 457-469.
    • (2005) Free Radic. Res. , vol.39 , pp. 457-469
    • Williamson, G.1    Barron, D.2    Shimoi, K.3    Terao, J.4
  • 19
    • 0030071445 scopus 로고    scopus 로고
    • Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones
    • Katzenellenbogen, J. A., OMalley, B. W., Katzenellenbogen, B. S., Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones. Mol. Endocrinol. 1996, 10, 119-131.
    • (1996) Mol. Endocrinol. , vol.10 , pp. 119-131
    • Katzenellenbogen, J.A.1    Omalley, B.W.2    Katzenellenbogen, B.S.3
  • 21
    • 0842347421 scopus 로고    scopus 로고
    • Metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes
    • Nikolic, D., Li, Y., Chadwick, L. R., Grubjesic, S. et al., Metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes. Drug Metab. Dispos. 2004, 32, 272-279.
    • (2004) Drug Metab. Dispos. , vol.32 , pp. 272-279
    • Nikolic, D.1    Li, Y.2    Chadwick, L.R.3    Grubjesic, S.4
  • 22
    • 33845539126 scopus 로고    scopus 로고
    • Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors α and β
    • Roelens, F., Heldring, N., Dhooge, W., Bengtsson, M. et al., Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors α and β. J. Med. Chem. 2006, 49, 7357-7365.
    • (2006) J. Med. Chem. , vol.49 , pp. 7357-7365
    • Roelens, F.1    Heldring, N.2    Dhooge, W.3    Bengtsson, M.4
  • 23
    • 0015036513 scopus 로고
    • Eine Mikromethode zur Kreatininbestimmung
    • Bartels, H., Bohmer, M., Eine Mikromethode zur Kreatininbestimmung. Clin. Chim. Acta 1971, 31, 81-85.
    • (1971) Clin. Chim. Acta , vol.31 , pp. 81-85
    • Bartels, H.1    Bohmer, M.2
  • 24
    • 72249100824 scopus 로고    scopus 로고
    • Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17β-estradiol equivalents
    • Bolca, S., Wyns, C., Possemiers, S., Depypere, H. et al., Cosupplementation of isoflavones, prenylflavonoids, and lignans alters human exposure to phytoestrogen-derived 17β-estradiol equivalents. J. Nutr. 2009, 139, 2293-2300.
    • (2009) J. Nutr. , vol.139 , pp. 2293-2300
    • Bolca, S.1    Wyns, C.2    Possemiers, S.3    Depypere, H.4
  • 25
    • 2442617185 scopus 로고    scopus 로고
    • Determination of reference intervals for serum creatinine, creatinine excretion and creatinine clearance with an enzymatic and a modified Jaffé method
    • Junge, W., Wilke, B., Halabi, A., Klein, G., Determination of reference intervals for serum creatinine, creatinine excretion and creatinine clearance with an enzymatic and a modified Jaffé method. Clin. Chim. Acta 2004, 344, 137-148.
    • (2004) Clin. Chim. Acta , vol.344 , pp. 137-148
    • Junge, W.1    Wilke, B.2    Halabi, A.3    Klein, G.4
  • 26
    • 0034016224 scopus 로고    scopus 로고
    • Comparison of estrogen concentrations, estrone sulfatase and aromatase activities in normal, and in cancerous, human breast tissues
    • Chetrite, G. S., Cortes-Prieto, J., Philippe, J. C., Wright, F., Pasqualini, J. R., Comparison of estrogen concentrations, estrone sulfatase and aromatase activities in normal, and in cancerous, human breast tissues. J. Steroid Biochem. Mol. Biol. 2000, 72, 23-27.
    • (2000) J. Steroid Biochem. Mol. Biol. , vol.72 , pp. 23-27
    • Chetrite, G.S.1    Cortes-Prieto, J.2    Philippe, J.C.3    Wright, F.4    Pasqualini, J.R.5
  • 27
    • 27644500107 scopus 로고    scopus 로고
    • Increased extracellular local levels of estradiol in normal breast in vivo during the luteal phase of the menstrual cycle
    • Dabrosin, C., Increased extracellular local levels of estradiol in normal breast in vivo during the luteal phase of the menstrual cycle. J. Endocrinol. 2005, 187, 103-108.
    • (2005) J. Endocrinol. , vol.187 , pp. 103-108
    • Dabrosin, C.1
  • 28
    • 33747067740 scopus 로고    scopus 로고
    • Pharmacokinetics and systemic endocrine effects of the phyto-oestrogen 8-prenylnaringenin after single oral doses to postmenopausal women
    • Rad, M., Hümpel, M., Schoemaker, R. C., Schleuning, W.-D. et al., Pharmacokinetics and systemic endocrine effects of the phyto-oestrogen 8-prenylnaringenin after single oral doses to postmenopausal women. Br. J. Clin. Pharmacol. 2006, 62, 288-296.
    • (2006) Br. J. Clin. Pharmacol. , vol.62 , pp. 288-296
    • Rad, M.1    Hümpel, M.2    Schoemaker, R.C.3    Schleuning, W.-D.4
  • 29
    • 0036728052 scopus 로고    scopus 로고
    • Cancer chemopreventive activity of xanthohumol, a natural product derived from hop
    • Gerhäuser, C., Alt, A., Heiss, E., Gamal-Eldeen, A. et al., Cancer chemopreventive activity of xanthohumol, a natural product derived from hop. Mol. Cancer Therap. 2002, 1, 959-969.
    • (2002) Mol. Cancer Therap. , vol.1 , pp. 959-969
    • Gerhäuser, C.1    Alt, A.2    Heiss, E.3    Gamal-Eldeen, A.4
  • 30
    • 33645232044 scopus 로고    scopus 로고
    • Effects of 8-prenylnaringenin on the hypothalamo-pituitary-uterine axis in rats after 3-months treatment
    • Christoffel, J., Rimoldi, G., Wuttke, W., Effects of 8-prenylnaringenin on the hypothalamo-pituitary-uterine axis in rats after 3-months treatment. J. Endocrinol. 2006, 188, 397-405.
    • (2006) J. Endocrinol. , vol.188 , pp. 397-405
    • Christoffel, J.1    Rimoldi, G.2    Wuttke, W.3
  • 31
    • 33646531814 scopus 로고    scopus 로고
    • Effect of hop (Humulus lupulus L.) flavonoids on aromatase (estrogen synthase) activity
    • Monteiro, R., Becker, H., Azevedo, I., Calhau, C., Effect of hop (Humulus lupulus L.) flavonoids on aromatase (estrogen synthase) activity. J. Agric. Food Chem. 2006, 54, 2938-2943.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 2938-2943
    • Monteiro, R.1    Becker, H.2    Azevedo, I.3    Calhau, C.4
  • 32
    • 34547681712 scopus 로고    scopus 로고
    • Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupulus L.) flavonoids
    • Monteiro, R., Faria, A., Azevedo, I., Calhau, C., Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupulus L.) flavonoids. J. Steroid Biochem. Mol. Biol. 2007, 105, 124-130.
    • (2007) J. Steroid Biochem. Mol. Biol. , vol.105 , pp. 124-130
    • Monteiro, R.1    Faria, A.2    Azevedo, I.3    Calhau, C.4
  • 33
    • 1042291170 scopus 로고    scopus 로고
    • 8-prenylnaringenin, a novel phytoestrogen, inhibits angiogenesis in vitro and in vivo
    • Pepper, M. S., Hazel, S. J., Hümpel, M., Schleuning, W.-D., 8-prenylnaringenin, a novel phytoestrogen, inhibits angiogenesis in vitro and in vivo. J. Cell. Physiol. 2004, 199, 98-107.
    • (2004) J. Cell. Physiol. , vol.199 , pp. 98-107
    • Pepper, M.S.1    Hazel, S.J.2    Hümpel, M.3    Schleuning, W.-D.4
  • 34
    • 53149105189 scopus 로고    scopus 로고
    • In vivo estrogenic comparisons of Trifolium pratense (red clover), Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin
    • Overk, C. R., Guo, J., Chadwick, L. R., Lantvit, D. D. et al., In vivo estrogenic comparisons of Trifolium pratense (red clover), Humulus lupulus (hops), and the pure compounds isoxanthohumol and 8-prenylnaringenin. Chem. Biol. Interact. 2008, 176, 30-39.
    • (2008) Chem. Biol. Interact. , vol.176 , pp. 30-39
    • Overk, C.R.1    Guo, J.2    Chadwick, L.R.3    Lantvit, D.D.4
  • 35
    • 58749092517 scopus 로고    scopus 로고
    • Effects of isoflavone supplements vs. soy foods on blood concentrations of genistein and daidzein in adults
    • Gardner, C. D., Chatterjee, L. M., Franke, A. A., Effects of isoflavone supplements vs. soy foods on blood concentrations of genistein and daidzein in adults. J. Nutr. Biochem. 2009, 20, 227-234.
    • (2009) J. Nutr. Biochem. , vol.20 , pp. 227-234
    • Gardner, C.D.1    Chatterjee, L.M.2    Franke, A.A.3
  • 36
    • 17144388229 scopus 로고    scopus 로고
    • Development of a radioimmunoassay for the quantitative determination of 8-prenylnaringenin in biological matrices
    • Schaefer, O., Bohlmann, R., Schleuning, W.-D., Schulze-Forster, K., Hümpel, M., Development of a radioimmunoassay for the quantitative determination of 8-prenylnaringenin in biological matrices. J. Agric. Food Chem. 2005, 53, 2881-2889.
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 2881-2889
    • Schaefer, O.1    Bohlmann, R.2    Schleuning, W.-D.3    Schulze-Forster, K.4    Hümpel, M.5
  • 37
    • 0033305279 scopus 로고    scopus 로고
    • Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast
    • Hargreaves, D. F., Potten, C. S., Harding, C., Shaw, L. E. et al., Two-week dietary soy supplementation has an estrogenic effect on normal premenopausal breast. J. Clin. Endocrinol. Metab. 1999, 84, 4017-4024.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 4017-4024
    • Hargreaves, D.F.1    Potten, C.S.2    Harding, C.3    Shaw, L.E.4
  • 38
    • 2942752003 scopus 로고    scopus 로고
    • Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids
    • Maubach, J., Depypere, H. T., Goeman, J., Van Der Eycken, J. et al., Distribution of soy-derived phytoestrogens in human breast tissue and biological fluids. Obstet. Gynecol. 2004, 103, 892-898.
    • (2004) Obstet. Gynecol. , vol.103 , pp. 892-898
    • Maubach, J.1    Depypere, H.T.2    Goeman, J.3    Van Der Eycken, J.4
  • 39
    • 33646855791 scopus 로고    scopus 로고
    • In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen form hops (Humulus lupulus L.)
    • Nikolic, D., Li, Y., Chadwick, L. R., van Breemen, R. B., In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen form hops (Humulus lupulus L.). Pharm. Res. 2006, 23, 864-872.
    • (2006) Pharm. Res. , vol.23 , pp. 864-872
    • Nikolic, D.1    Li, Y.2    Chadwick, L.R.3    van Breemen, R.B.4
  • 40
    • 26244462955 scopus 로고    scopus 로고
    • In vitro phase II metabolism of xanthohumol by human UDP-glucuronosyltransferases and sulfotransferases
    • Ruefer, C. E., Gerhäuser, C., Frank, N., Becker, H., Kulling, S. E., In vitro phase II metabolism of xanthohumol by human UDP-glucuronosyltransferases and sulfotransferases. Mol. Nutr. Food Res. 2005, 49, 851-856.
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 851-856
    • Ruefer, C.E.1    Gerhäuser, C.2    Frank, N.3    Becker, H.4    Kulling, S.E.5
  • 41
    • 0035793965 scopus 로고    scopus 로고
    • In vitro glucuronidation of xanthohumol, a flavonoid in hop and beer, by rat and human liver microsomes
    • Yilmazer, M., Stevens, J. F., Buhler, D. R., In vitro glucuronidation of xanthohumol, a flavonoid in hop and beer, by rat and human liver microsomes. FEBS Lett. 2001, 491, 252-256.
    • (2001) FEBS Lett. , vol.491 , pp. 252-256
    • Yilmazer, M.1    Stevens, J.F.2    Buhler, D.R.3
  • 42
    • 77950493405 scopus 로고    scopus 로고
    • Disposition of soy isoflavones in normal human breast tissue
    • Bolca, S., Urpi-Sarda, M., Blondeel, P., Roche, N. et al., Disposition of soy isoflavones in normal human breast tissue. Am. J. Clin. Nutr. 2010, 91, 976-984.
    • (2010) Am. J. Clin. Nutr. , vol.91 , pp. 976-984
    • Bolca, S.1    Urpi-Sarda, M.2    Blondeel, P.3    Roche, N.4
  • 43
    • 0034062036 scopus 로고    scopus 로고
    • Analysis of soy isoflavone conjugation in vitro and in human blood using liquid chromatography-mass spectrometry
    • Doerge, D. R., Chang, H. C., Churchwell, M. I., Holder, C. L., Analysis of soy isoflavone conjugation in vitro and in human blood using liquid chromatography-mass spectrometry. Drug Metab. Dispos. 2000, 28, 298-307.
    • (2000) Drug Metab. Dispos. , vol.28 , pp. 298-307
    • Doerge, D.R.1    Chang, H.C.2    Churchwell, M.I.3    Holder, C.L.4
  • 44
    • 46349093383 scopus 로고    scopus 로고
    • Orally administered isoflavones are present as glucuronides in the human prostate
    • Guy, L., Vedrine, N., Urpi-Sarda, M., Gil-Izquierdo, A. et al., Orally administered isoflavones are present as glucuronides in the human prostate. Nutr. Cancer 2008, 60, 461-468.
    • (2008) Nutr. Cancer , vol.60 , pp. 461-468
    • Guy, L.1    Vedrine, N.2    Urpi-Sarda, M.3    Gil-Izquierdo, A.4
  • 45
    • 47949092138 scopus 로고    scopus 로고
    • Plasma profiling of intact isoflavone metabolites by high-performance liquid chromatography and mass spectrometric identification of flavone glycosides daidzin and genistin in human plasma after administration of kinako
    • Hosoda, K., Furuta, T., Yokokawa, A., Ogura, K. et al., Plasma profiling of intact isoflavone metabolites by high-performance liquid chromatography and mass spectrometric identification of flavone glycosides daidzin and genistin in human plasma after administration of kinako. Drug Metab. Dispos. 2008, 36, 1485-1495.
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 1485-1495
    • Hosoda, K.1    Furuta, T.2    Yokokawa, A.3    Ogura, K.4
  • 46
    • 0036721557 scopus 로고    scopus 로고
    • Pharmacokinetics of the glucuronide and sulfate conjugates of genistein and daidzein in men and women after consumption of a soy beverage
    • Shelnutt, S. R., Cimino, C. O., Wiggins, P. A., Ronis, M. J. J., Badger, T. M., Pharmacokinetics of the glucuronide and sulfate conjugates of genistein and daidzein in men and women after consumption of a soy beverage. Am. J. Clin. Nutr. 2002, 76, 588-594.
    • (2002) Am. J. Clin. Nutr. , vol.76 , pp. 588-594
    • Shelnutt, S.R.1    Cimino, C.O.2    Wiggins, P.A.3    Ronis, M.J.J.4    Badger, T.M.5
  • 47
    • 0037315155 scopus 로고    scopus 로고
    • Glucuronides are the main isoflavone metabolites in women
    • Zhang, Y., Hendrich, S., Murphy, P. A., Glucuronides are the main isoflavone metabolites in women. J. Nutr. 2003, 133, 399-404.
    • (2003) J. Nutr. , vol.133 , pp. 399-404
    • Zhang, Y.1    Hendrich, S.2    Murphy, P.A.3
  • 48
    • 34648837212 scopus 로고    scopus 로고
    • Estrogen and tibolone metabolite levels in blood and breast tissue of postmenopausal women recently diagnosed with early-stage breast cancer and treated with tibolone or placebo for 14 days
    • Kloosterboer, H. J., Lofgren, L., von Schoulz, E., von Schoulz, B., Verheul, H. A. M., Estrogen and tibolone metabolite levels in blood and breast tissue of postmenopausal women recently diagnosed with early-stage breast cancer and treated with tibolone or placebo for 14 days. Reprod. Sci. 2007, 14, 151-159.
    • (2007) Reprod. Sci. , vol.14 , pp. 151-159
    • Kloosterboer, H.J.1    Lofgren, L.2    von Schoulz, E.3    von Schoulz, B.4    Verheul, H.A.M.5
  • 49
    • 0033386954 scopus 로고    scopus 로고
    • Estrogen receptor β - a new dimension in estrogen mechanism of action
    • Gustafsson, J. A., Estrogen receptor β - a new dimension in estrogen mechanism of action. J. Endocrinol. 1999, 163, 379-383.
    • (1999) J. Endocrinol. , vol.163 , pp. 379-383
    • Gustafsson, J.A.1
  • 50
    • 0026724017 scopus 로고
    • Further evidence that morphine-6-β-glucuronide is a more potent opioid agonist than morphine
    • Frances, B., Gout, R., Monsarrat, B., Cros, J., Zajac, J. M., Further evidence that morphine-6-β-glucuronide is a more potent opioid agonist than morphine. J. Pharmacol. Exp. Ther. 1992, 262, 477-480.
    • (1992) J. Pharmacol. Exp. Ther. , vol.262 , pp. 477-480
    • Frances, B.1    Gout, R.2    Monsarrat, B.3    Cros, J.4    Zajac, J.M.5
  • 51
    • 34748865637 scopus 로고    scopus 로고
    • Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation
    • Zheng, Y., Sun, D., Sharma, A. K., Chen, G. et al., Elimination of antiestrogenic effects of active tamoxifen metabolites by glucuronidation. Drug Metab. Dispos. 2007, 35, 1942-1948.
    • (2007) Drug Metab. Dispos. , vol.35 , pp. 1942-1948
    • Zheng, Y.1    Sun, D.2    Sharma, A.K.3    Chen, G.4
  • 52
    • 14344264789 scopus 로고    scopus 로고
    • Interactions of phytoestrogens with estrogen receptors α and β (III). Estrogenic activities of soy isoflavone aglycones and their metabolites isolated from human urine
    • Kinjo, J., Tsuchihashi, R., Morito, K., Hirose, T. et al., Interactions of phytoestrogens with estrogen receptors α and β (III). Estrogenic activities of soy isoflavone aglycones and their metabolites isolated from human urine. Biol. Pharm. Bull. 2004, 27, 185-188.
    • (2004) Biol. Pharm. Bull. , vol.27 , pp. 185-188
    • Kinjo, J.1    Tsuchihashi, R.2    Morito, K.3    Hirose, T.4
  • 53
    • 0032964360 scopus 로고    scopus 로고
    • Daidzein and genistein glucuronides in vitro are weakly estrogenic and activate human natural killer cells at nutritionally relevant concentrations
    • Zhang, Y., Song, T. T., Cunnick, J. E., Murphy, P. A., Hendrich, S., Daidzein and genistein glucuronides in vitro are weakly estrogenic and activate human natural killer cells at nutritionally relevant concentrations. J. Nutr. 1999, 129, 399-405.
    • (1999) J. Nutr. , vol.129 , pp. 399-405
    • Zhang, Y.1    Song, T.T.2    Cunnick, J.E.3    Murphy, P.A.4    Hendrich, S.5
  • 54
    • 53149113807 scopus 로고    scopus 로고
    • Glucuronidation of the soyabean isoflavones genistein and daidzein by human liver is related to levels of UGT1A1 and UGT1A9 activity and alters isoflavone response in the MCF-7 human breast cancer cell line
    • Prichett, L. E., Atherton, K. M., Mutch, E., Ford, D., Glucuronidation of the soyabean isoflavones genistein and daidzein by human liver is related to levels of UGT1A1 and UGT1A9 activity and alters isoflavone response in the MCF-7 human breast cancer cell line. J. Nutr. Biochem. 2008, 19, 739-745.
    • (2008) J. Nutr. Biochem. , vol.19 , pp. 739-745
    • Prichett, L.E.1    Atherton, K.M.2    Mutch, E.3    Ford, D.4
  • 56
    • 0030855601 scopus 로고    scopus 로고
    • Differences in the estrogen content of breast adipose tissue in women by menopausal status and hormone use
    • O'Brien, S. N., Anandjiwala, J., Price, T. M., Differences in the estrogen content of breast adipose tissue in women by menopausal status and hormone use. Obstet. Gynecol. 1997, 90, 244-248.
    • (1997) Obstet. Gynecol. , vol.90 , pp. 244-248
    • O'Brien, S.N.1    Anandjiwala, J.2    Price, T.M.3
  • 57
    • 0030887513 scopus 로고    scopus 로고
    • Concentrations of estrone, estradiol and their sulfates, and evaluation of sulfatase and aromatase activities in patients with breast fibroadenoma
    • Pasqualini, J. R., Cortes-Prieto, J., Chetrite, G., Talbi, M., Ruiz, A., Concentrations of estrone, estradiol and their sulfates, and evaluation of sulfatase and aromatase activities in patients with breast fibroadenoma. Int. J. Cancer 1997, 70, 639-643.
    • (1997) Int. J. Cancer , vol.70 , pp. 639-643
    • Pasqualini, J.R.1    Cortes-Prieto, J.2    Chetrite, G.3    Talbi, M.4    Ruiz, A.5
  • 58
    • 0021931084 scopus 로고
    • Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue
    • van Landeghem, A. A. J., Poortman, J., Nabuurs, M., Thijssen, J. H. H., Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue. Cancer Res. 1985, 45, 2900-2906.
    • (1985) Cancer Res. , vol.45 , pp. 2900-2906
    • van Landeghem, A.A.J.1    Poortman, J.2    Nabuurs, M.3    Thijssen, J.H.H.4
  • 59
    • 18044372636 scopus 로고    scopus 로고
    • Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer
    • Pasqualini, J. R., Chetrite, G. S., Recent insight on the control of enzymes involved in estrogen formation and transformation in human breast cancer. J. Steroid Biochem. Mol. Biol. 2005, 93, 221-236.
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.93 , pp. 221-236
    • Pasqualini, J.R.1    Chetrite, G.S.2
  • 60
    • 33646535267 scopus 로고    scopus 로고
    • Concentrations of isoflavones in plasma and urine of post-menopausal women chronically ingesting high quantities of soy isoflavones
    • Mathey, J., Lamothe, V., Coxam, V., Potier, M. et al., Concentrations of isoflavones in plasma and urine of post-menopausal women chronically ingesting high quantities of soy isoflavones. J. Pharm. Biomed. Anal. 2006, 41, 957-965.
    • (2006) J. Pharm. Biomed. Anal. , vol.41 , pp. 957-965
    • Mathey, J.1    Lamothe, V.2    Coxam, V.3    Potier, M.4
  • 61
    • 24044475615 scopus 로고    scopus 로고
    • Bioavailability of isoflavone phytoestrogens in postmenopausal women consuming soya milk fermented with probiotic bifidobacteria
    • Tsangalis, D., Wilcox, G., Shah, N. P., Stojanovska, L., Bioavailability of isoflavone phytoestrogens in postmenopausal women consuming soya milk fermented with probiotic bifidobacteria. Br. J. Nutr. 2005, 93, 867-877.
    • (2005) Br. J. Nutr. , vol.93 , pp. 867-877
    • Tsangalis, D.1    Wilcox, G.2    Shah, N.P.3    Stojanovska, L.4
  • 62
    • 0027203699 scopus 로고
    • Main drug-metabolizing enzyme systems in human breast tumors and peritumoral tissues
    • Albin, N., Massaad, L., Toussaint, C., Mathieu, M.-C. et al., Main drug-metabolizing enzyme systems in human breast tumors and peritumoral tissues. Cancer Res. 1993, 53, 3541-3546.
    • (1993) Cancer Res. , vol.53 , pp. 3541-3546
    • Albin, N.1    Massaad, L.2    Toussaint, C.3    Mathieu, M.-C.4
  • 63
    • 0029872530 scopus 로고    scopus 로고
    • Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients
    • Pasqualini, J. R., Chetrite, G., Blacker, C., Feinstein, M. C. et al., Concentrations of estrone, estradiol, and estrone sulfate and evaluation of sulfatase and aromatase activities in pre- and postmenopausal breast cancer patients. J. Clin. Endocrinol. Metab. 1996, 81, 1460-1464.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 1460-1464
    • Pasqualini, J.R.1    Chetrite, G.2    Blacker, C.3    Feinstein, M.C.4
  • 64
    • 65349116538 scopus 로고    scopus 로고
    • Bioassays for estrogenic activity: development and validation of estrogen receptor (ERα/ERβ) and breast cancer proliferation bioassays to measure serum estrogenic activity in clinical trials
    • Li, J., Lee, L., Gong, Y., Shen, P. et al., Bioassays for estrogenic activity: development and validation of estrogen receptor (ERα/ERβ) and breast cancer proliferation bioassays to measure serum estrogenic activity in clinical trials. Assay Drug Develop. Technol. 2009, 7, 80-89.
    • (2009) Assay Drug Develop. Technol. , vol.7 , pp. 80-89
    • Li, J.1    Lee, L.2    Gong, Y.3    Shen, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.