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Volumn 4, Issue 1, 2009, Pages 22-29

Isoflavones - Mechanism of action and impact on breast cancer risk

Author keywords

Breast cancer; Isoflavones; Nutrition; Phytoestrogens; Prevention; Risk factors

Indexed keywords

COUMESTROL; DAIDZEIN; ESTRADIOL; ESTROGEN RECEPTOR; GENISTEIN; GLYCITEIN; HORMONE ANTAGONIST; ISOFLAVONE DERIVATIVE; LETROZOLE; PHYTOESTROGEN; PLACEBO; TAMOXIFEN; TUMOR MARKER;

EID: 62849090724     PISSN: 16613791     EISSN: 16613805     Source Type: Journal    
DOI: 10.1159/000200980     Document Type: Review
Times cited : (22)

References (81)
  • 2
    • 28444490702 scopus 로고    scopus 로고
    • Nutrition and primary prevention of breast cancer: Foods, nutrients and breast cancer risk
    • Hanf V, Gonder U: Nutrition and primary prevention of breast cancer: foods, nutrients and breast cancer risk. Eur J Obstet Gynecol Reprod Biol 2005;123:139-149.
    • (2005) Eur J Obstet Gynecol Reprod Biol , vol.123 , pp. 139-149
    • Hanf, V.1    Gonder, U.2
  • 4
    • 38049025267 scopus 로고    scopus 로고
    • Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women
    • Khaodhiar L, Ricciotti HA, Li L, Pan W, Schickel M, Zhou J, Blackburn GL: Daidzein-rich isoflavone aglycones are potentially effective in reducing hot flashes in menopausal women. Menopause 2008;15:125-132.
    • (2008) Menopause , vol.15 , pp. 125-132
    • Khaodhiar, L.1    Ricciotti, H.A.2    Li, L.3    Pan, W.4    Schickel, M.5    Zhou, J.6    Blackburn, G.L.7
  • 5
    • 36148965182 scopus 로고    scopus 로고
    • Efficacy and safety of a soy isoflavone extract in postmenopausal women: A randomized, double-blind, and placebo-controlled study
    • Nahas EA, Nahas-Neto J, Orsatti FL, Carvalho EP, Oliveira ML, Dias R: Efficacy and safety of a soy isoflavone extract in postmenopausal women: a randomized, double-blind, and placebo-controlled study. Maturitas 2007;58:249-258.
    • (2007) Maturitas , vol.58 , pp. 249-258
    • Nahas, E.A.1    Nahas-Neto, J.2    Orsatti, F.L.3    Carvalho, E.P.4    Oliveira, M.L.5    Dias, R.6
  • 6
    • 0035655534 scopus 로고    scopus 로고
    • Substances with estrogenic activity in effluents of sewage treatment plants in southwestern Germany. 2. Biological analysis
    • Korner W, Spengler P, Bolz U, Schuller W, Hanf V, Metzger JW: Substances with estrogenic activity in effluents of sewage treatment plants in southwestern Germany. 2. Biological analysis. Environ Toxicol Chem 2001;20:2142-2151.
    • (2001) Environ Toxicol Chem , vol.20 , pp. 2142-2151
    • Korner, W.1    Spengler, P.2    Bolz, U.3    Schuller, W.4    Hanf, V.5    Metzger, J.W.6
  • 7
    • 0032191434 scopus 로고    scopus 로고
    • Validation and application of a rapid in vitro assay for assessing the estrogenic potency of halogenated phenolic chemicals
    • Korner W, Hanf V, Schuller W, Bartsch H, Zwirner M, Hagenmaier H: Validation and application of a rapid in vitro assay for assessing the estrogenic potency of halogenated phenolic chemicals. Chemosphere 1998;37:2395-2407.
    • (1998) Chemosphere , vol.37 , pp. 2395-2407
    • Korner, W.1    Hanf, V.2    Schuller, W.3    Bartsch, H.4    Zwirner, M.5    Hagenmaier, H.6
  • 10
    • 33750205003 scopus 로고    scopus 로고
    • Isoflavone metabolites and their in vitro dual functions: They can act as an estrogenic agonist or antagonist depending on the estrogen concentration
    • Hwang CS, Kwak HS, Lim HJ, Lee SH, Kang YS, Choe TB, Hur HG, Han KO: Isoflavone metabolites and their in vitro dual functions: they can act as an estrogenic agonist or antagonist depending on the estrogen concentration. J Steroid Biochem Mol Biol 2006;101:246-253.
    • (2006) J Steroid Biochem Mol Biol , vol.101 , pp. 246-253
    • Hwang, C.S.1    Kwak, H.S.2    Lim, H.J.3    Lee, S.H.4    Kang, Y.S.5    Choe, T.B.6    Hur, H.G.7    Han, K.O.8
  • 11
    • 0034829143 scopus 로고    scopus 로고
    • Effects of soy phytoestrogens genistein and daidzein on breast cancer growth
    • De Lemos ML: Effects of soy phytoestrogens genistein and daidzein on breast cancer growth. Ann Pharmacother 2001;35:1118-1121.
    • (2001) Ann Pharmacother , vol.35 , pp. 1118-1121
    • De Lemos, M.L.1
  • 12
    • 0032994684 scopus 로고    scopus 로고
    • Phytoestrogens: The 'natural' selective estrogen receptor modulators?
    • Brzezinski A, Debi A: Phytoestrogens: the 'natural' selective estrogen receptor modulators? Eur J Obstet Gynecol Reprod Biol 1999;85:47-51.
    • (1999) Eur J Obstet Gynecol Reprod Biol , vol.85 , pp. 47-51
    • Brzezinski, A.1    Debi, A.2
  • 14
    • 38049109784 scopus 로고    scopus 로고
    • The red clover (Trifolium pratense) isoflavone biochanin A inhibits aromatase activity and expression
    • Wang Y, Man GW, Chan FL, Chen S, Leung LK: The red clover (Trifolium pratense) isoflavone biochanin A inhibits aromatase activity and expression. Br J Nutr 2008;99:303-310.
    • (2008) Br J Nutr , vol.99 , pp. 303-310
    • Wang, Y.1    Man, G.W.2    Chan, F.L.3    Chen, S.4    Leung, L.K.5
  • 15
    • 33846882142 scopus 로고    scopus 로고
    • Phytoestrogens and breast cancer - promoters or protectors?
    • Rice S, Whitehead SA: Phytoestrogens and breast cancer - promoters or protectors? Endocr Relat Cancer 2006;13:995-1015.
    • (2006) Endocr Relat Cancer , vol.13 , pp. 995-1015
    • Rice, S.1    Whitehead, S.A.2
  • 17
    • 39749140314 scopus 로고    scopus 로고
    • Modulation of gene methylation by genistein or lycopene in breast cancer cells
    • King-Batoon A, Leszczynska JM, Klein CB: Modulation of gene methylation by genistein or lycopene in breast cancer cells. Environ Mol Mutagen 2008;49:36-45.
    • (2008) Environ Mol Mutagen , vol.49 , pp. 36-45
    • King-Batoon, A.1    Leszczynska, J.M.2    Klein, C.B.3
  • 19
    • 33645214868 scopus 로고    scopus 로고
    • Complementary and alternative therapeutic approaches in patients with early breast cancer: A systematic review
    • Gerber B, Scholz C, Reimer T, Briese V, Janni W: Complementary and alternative therapeutic approaches in patients with early breast cancer: a systematic review. Breast Cancer Res Treat 2006;95:199-209.
    • (2006) Breast Cancer Res Treat , vol.95 , pp. 199-209
    • Gerber, B.1    Scholz, C.2    Reimer, T.3    Briese, V.4    Janni, W.5
  • 20
    • 29544449397 scopus 로고    scopus 로고
    • The effects of dietary phytoestrogens on aromatase activity in human endometrial stromal cells
    • Edmunds KM, Holloway AC, Crankshaw DJ, Agarwal SK, Foster WG: The effects of dietary phytoestrogens on aromatase activity in human endometrial stromal cells. Reprod Nutr Dev 2005;45:709-720.
    • (2005) Reprod Nutr Dev , vol.45 , pp. 709-720
    • Edmunds, K.M.1    Holloway, A.C.2    Crankshaw, D.J.3    Agarwal, S.K.4    Foster, W.G.5
  • 22
    • 41549089204 scopus 로고    scopus 로고
    • Isolation and identification of equol-producing bacterial strains from cultures of pig faeces
    • Yu ZT, Yao W, Zhu WY: Isolation and identification of equol-producing bacterial strains from cultures of pig faeces. FEMS Microbiol Lett 2008;282:73-80.
    • (2008) FEMS Microbiol Lett , vol.282 , pp. 73-80
    • Yu, Z.T.1    Yao, W.2    Zhu, W.Y.3
  • 23
    • 38749086483 scopus 로고    scopus 로고
    • Oral antibiotics decrease urinary isoflavonoid excretion in children after soy consumption
    • Halm BM, Franke AA, Ashburn LA, Hebshi SM, Wilkens LR: Oral antibiotics decrease urinary isoflavonoid excretion in children after soy consumption. Nutr Cancer 2008;60:14-22.
    • (2008) Nutr Cancer , vol.60 , pp. 14-22
    • Halm, B.M.1    Franke, A.A.2    Ashburn, L.A.3    Hebshi, S.M.4    Wilkens, L.R.5
  • 26
    • 0031741906 scopus 로고    scopus 로고
    • Phytoestrogens: The biochemistry, physiology, and implications for human health of soy isoflavones
    • Setchell KD: Phytoestrogens: the biochemistry, physiology, and implications for human health of soy isoflavones. Am J Clin Nutr 1998;68:1333S-1346S.
    • (1998) Am J Clin Nutr , vol.68
    • Setchell, K.D.1
  • 27
    • 0033005675 scopus 로고    scopus 로고
    • Usual dietary consumption of soy foods and its correlation with the excretion rate of isoflavonoids in overnight urine samples among Chinese women in Shanghai
    • Chen Z, Zheng W, Custer LJ, Dai Q, Shu XO, Jin F, Franke AA: Usual dietary consumption of soy foods and its correlation with the excretion rate of isoflavonoids in overnight urine samples among Chinese women in Shanghai. Nutr Cancer 1999;33:82-87.
    • (1999) Nutr Cancer , vol.33 , pp. 82-87
    • Chen, Z.1    Zheng, W.2    Custer, L.J.3    Dai, Q.4    Shu, X.O.5    Jin, F.6    Franke, A.A.7
  • 29
    • 33751557472 scopus 로고    scopus 로고
    • Estimated intakes of isoflavones and coumestrol in Korean population
    • Surh J, Kim MJ, Koh E, Kim YK, Kwon H: Estimated intakes of isoflavones and coumestrol in Korean population. Int J Food Sci Nutr 2006;57:325-344.
    • (2006) Int J Food Sci Nutr , vol.57 , pp. 325-344
    • Surh, J.1    Kim, M.J.2    Koh, E.3    Kim, Y.K.4    Kwon, H.5
  • 30
    • 33846988236 scopus 로고    scopus 로고
    • Intakes and sources of soya foods and isoflavones in a UK population cohort study (EPIC-Norfolk)
    • Mulligan AA, Welch AA, McTaggart AA, Bhaniani A, Bingham SA: Intakes and sources of soya foods and isoflavones in a UK population cohort study (EPIC-Norfolk). Eur J Clin Nutr 2007;61:248-254.
    • (2007) Eur J Clin Nutr , vol.61 , pp. 248-254
    • Mulligan, A.A.1    Welch, A.A.2    McTaggart, A.A.3    Bhaniani, A.4    Bingham, S.A.5
  • 33
    • 0034017220 scopus 로고    scopus 로고
    • Sources of phytoestrogen exposure among non-Asian women in California, USA
    • Horn-Ross PL, Lee M, John EM, Koo J: Sources of phytoestrogen exposure among non-Asian women in California, USA. Cancer Causes Control 2000;11:299-302.
    • (2000) Cancer Causes Control , vol.11 , pp. 299-302
    • Horn-Ross, P.L.1    Lee, M.2    John, E.M.3    Koo, J.4
  • 35
    • 38049074972 scopus 로고    scopus 로고
    • Epidemiology of soy exposures and breast cancer risk
    • Wu AH, Yu MC, Tseng CC, Pike MC: Epidemiology of soy exposures and breast cancer risk. Br J Cancer 2008;98:9-14.
    • (2008) Br J Cancer , vol.98 , pp. 9-14
    • Wu, A.H.1    Yu, M.C.2    Tseng, C.C.3    Pike, M.C.4
  • 36
    • 46349109619 scopus 로고    scopus 로고
    • Soy intake and breast cancer risk in Singapore Chinese Health Study
    • Wu AH, Koh WP, Wang R, Lee HP, Yu MC: Soy intake and breast cancer risk in Singapore Chinese Health Study. Br J Cancer 2008;99:196-200.
    • (2008) Br J Cancer , vol.99 , pp. 196-200
    • Wu, A.H.1    Koh, W.P.2    Wang, R.3    Lee, H.P.4    Yu, M.C.5
  • 37
    • 43249092642 scopus 로고    scopus 로고
    • Plasma isoflavone level and subsequent risk of breast cancer among Japanese women: A nested case-control study from the Japan Public Health Center-based prospective study group
    • Iwasaki M, Inoue M, Otani T, Sasazuki S, Kurahashi N, Miura T, Yamamoto S, Tsugane S: Plasma isoflavone level and subsequent risk of breast cancer among Japanese women: a nested case-control study from the Japan Public Health Center-based prospective study group. J Clin Oncol 2008;26:1677-1683.
    • (2008) J Clin Oncol , vol.26 , pp. 1677-1683
    • Iwasaki, M.1    Inoue, M.2    Otani, T.3    Sasazuki, S.4    Kurahashi, N.5    Miura, T.6    Yamamoto, S.7    Tsugane, S.8
  • 40
    • 42449086271 scopus 로고    scopus 로고
    • Dietary phytoestrogens are not associated with risk of overall breast cancer but diets rich in coumestrol are inversely associated with risk of estrogen receptor and progesterone receptor negative breast tumors in Swedish women
    • Hedelin M, Lof M, Olsson M, Adlercreutz H, Sandin S, Weiderpass E: Dietary phytoestrogens are not associated with risk of overall breast cancer but diets rich in coumestrol are inversely associated with risk of estrogen receptor and progesterone receptor negative breast tumors in Swedish women. J Nutr 2008;138:938-945.
    • (2008) J Nutr , vol.138 , pp. 938-945
    • Hedelin, M.1    Lof, M.2    Olsson, M.3    Adlercreutz, H.4    Sandin, S.5    Weiderpass, E.6
  • 41
    • 37349007706 scopus 로고    scopus 로고
    • A prospective study of vegetarianism and isoflavone intake in relation to breast cancer risk in British women
    • Travis RC, Allen NE, Appleby PN, Spencer EA, Roddam AW, Key TJ: A prospective study of vegetarianism and isoflavone intake in relation to breast cancer risk in British women. Int J Cancer 2008;122:705-710.
    • (2008) Int J Cancer , vol.122 , pp. 705-710
    • Travis, R.C.1    Allen, N.E.2    Appleby, P.N.3    Spencer, E.A.4    Roddam, A.W.5    Key, T.J.6
  • 42
    • 48949119484 scopus 로고    scopus 로고
    • Breast cancer risk in relation to urinary and serum biomarkers of phytoestrogen exposure in the European Prospective into Cancer-Norfolk cohort study
    • Ward H, Chapelais G, Kuhnle GG, Luben R, Khaw KT, Bingham S: Breast cancer risk in relation to urinary and serum biomarkers of phytoestrogen exposure in the European Prospective into Cancer-Norfolk cohort study. Breast Cancer Res 2008;10:R32.
    • (2008) Breast Cancer Res , vol.10
    • Ward, H.1    Chapelais, G.2    Kuhnle, G.G.3    Luben, R.4    Khaw, K.T.5    Bingham, S.6
  • 44
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager JD, Davidson NE: Estrogen carcinogenesis in breast cancer. N Engl J Med 2006;354:270-282.
    • (2006) N Engl J Med , vol.354 , pp. 270-282
    • Yager, J.D.1    Davidson, N.E.2
  • 45
    • 46749111467 scopus 로고    scopus 로고
    • Soy isoflavones, estrogen therapy, and breast cancer risk: Analysis and commentary
    • Messina MJ, Wood CE: Soy isoflavones, estrogen therapy, and breast cancer risk: analysis and commentary. Nutr J 2008;7:17.
    • (2008) Nutr J , vol.7 , pp. 17
    • Messina, M.J.1    Wood, C.E.2
  • 51
    • 0038407920 scopus 로고    scopus 로고
    • Mammographic densities in a one-year isoflavone intervention
    • Maskarinec G, Williams AE, Carlin L: Mammographic densities in a one-year isoflavone intervention. Eur J Cancer Prev 2003;12:165-169.
    • (2003) Eur J Cancer Prev , vol.12 , pp. 165-169
    • Maskarinec, G.1    Williams, A.E.2    Carlin, L.3
  • 54
    • 0032170032 scopus 로고    scopus 로고
    • Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo
    • Hsieh CY, Santell RC, Haslam SZ, Helferich WG: Estrogenic effects of genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo. Cancer Res 1998;58:3833-3838.
    • (1998) Cancer Res , vol.58 , pp. 3833-3838
    • Hsieh, C.Y.1    Santell, R.C.2    Haslam, S.Z.3    Helferich, W.G.4
  • 55
    • 0035394121 scopus 로고    scopus 로고
    • Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner
    • Allred CD, Allred KF, Ju YH, Virant SM, Helferich WG: Soy diets containing varying amounts of genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner. Cancer Res 2001;61:5045-5050.
    • (2001) Cancer Res , vol.61 , pp. 5045-5050
    • Allred, C.D.1    Allred, K.F.2    Ju, Y.H.3    Virant, S.M.4    Helferich, W.G.5
  • 56
    • 0035158466 scopus 로고    scopus 로고
    • Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice
    • Ju YH, Allred CD, Allred KF, Karko KL, Doerge DR, Helferich WG: Physiological concentrations of dietary genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in athymic nude mice. J Nutr 2001;131:2957-2962.
    • (2001) J Nutr , vol.131 , pp. 2957-2962
    • Ju, Y.H.1    Allred, C.D.2    Allred, K.F.3    Karko, K.L.4    Doerge, D.R.5    Helferich, W.G.6
  • 57
    • 33645343013 scopus 로고    scopus 로고
    • Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice
    • Ju YH, Fultz J, Allred KF, Doerge DR, Helferich WG: Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in ovariectomized athymic mice. Carcinogenesis 2006;27:856-863.
    • (2006) Carcinogenesis , vol.27 , pp. 856-863
    • Ju, Y.H.1    Fultz, J.2    Allred, K.F.3    Doerge, D.R.4    Helferich, W.G.5
  • 58
    • 33745686651 scopus 로고    scopus 로고
    • Genistein stimulates growth of human breast cancer cells in a novel, postmenopausal animal model, with low plasma estradiol concentrations
    • Ju YH, Allred KF, Allred CD, Helferich WG: Genistein stimulates growth of human breast cancer cells in a novel, postmenopausal animal model, with low plasma estradiol concentrations. Carcinogenesis 2006;27:1292-1299.
    • (2006) Carcinogenesis , vol.27 , pp. 1292-1299
    • Ju, Y.H.1    Allred, K.F.2    Allred, C.D.3    Helferich, W.G.4
  • 59
    • 49349107640 scopus 로고    scopus 로고
    • Effects of soy isoflavones on 17beta-estradiol-induced proliferation of MCF-7 breast cancer cells
    • Imhof M, Molzer S, Imhof M: Effects of soy isoflavones on 17beta-estradiol-induced proliferation of MCF-7 breast cancer cells. Toxicol In Vitro 2008;22:1452-1460.
    • (2008) Toxicol In Vitro , vol.22 , pp. 1452-1460
    • Imhof, M.1    Molzer, S.2    Imhof, M.3
  • 60
    • 0036395342 scopus 로고    scopus 로고
    • Dietary supplementation with isolated soy protein reduces metastasis of mammary carcinoma cells in mice
    • Yan L, Li D, Yee JA: Dietary supplementation with isolated soy protein reduces metastasis of mammary carcinoma cells in mice. Clin Exp Metastasis 2002;19:535-540.
    • (2002) Clin Exp Metastasis , vol.19 , pp. 535-540
    • Yan, L.1    Li, D.2    Yee, J.A.3
  • 61
    • 55749085657 scopus 로고    scopus 로고
    • Soy extract is more potent than genistein on tumor growth inhibition
    • Kim HA, Jeong KS, Kim YK: Soy extract is more potent than genistein on tumor growth inhibition. Anticancer Res 2008;28:2837-2841.
    • (2008) Anticancer Res , vol.28 , pp. 2837-2841
    • Kim, H.A.1    Jeong, K.S.2    Kim, Y.K.3
  • 64
    • 0036569703 scopus 로고    scopus 로고
    • Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice
    • Ju YH, Doerge DR, Allred KF, Allred CD, Helferich WG: Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice. Cancer Res 2002;62:2474-2477.
    • (2002) Cancer Res , vol.62 , pp. 2474-2477
    • Ju, Y.H.1    Doerge, D.R.2    Allred, K.F.3    Allred, C.D.4    Helferich, W.G.5
  • 65
    • 33745463624 scopus 로고    scopus 로고
    • Differential response to phytoestrogens in endocrine sensitive and resistant breast cancer cells in vitro
    • Limer JL, Parkes AT, Speirs V: Differential response to phytoestrogens in endocrine sensitive and resistant breast cancer cells in vitro. Int J Cancer 2006;119:515-521.
    • (2006) Int J Cancer , vol.119 , pp. 515-521
    • Limer, J.L.1    Parkes, A.T.2    Speirs, V.3
  • 66
    • 34447296461 scopus 로고    scopus 로고
    • Soy phytochemicals synergistically enhance the preventive effect of tamoxifen on the growth of estrogen-dependent human breast carcinoma in mice
    • Mai Z, Blackburn GL, Zhou JR: Soy phytochemicals synergistically enhance the preventive effect of tamoxifen on the growth of estrogen-dependent human breast carcinoma in mice. Carcinogenesis 2007;28:1217-1223.
    • (2007) Carcinogenesis , vol.28 , pp. 1217-1223
    • Mai, Z.1    Blackburn, G.L.2    Zhou, J.R.3
  • 67
    • 34447542631 scopus 로고    scopus 로고
    • Genistein sensitizes inhibitory effect of tamoxifen on the growth of estrogen receptor-positive and HER2-overexpressing human breast cancer cells
    • Mai Z, Blackburn GL, Zhou JR: Genistein sensitizes inhibitory effect of tamoxifen on the growth of estrogen receptor-positive and HER2-overexpressing human breast cancer cells. Mol Carcinog 2007;46:534-542.
    • (2007) Mol Carcinog , vol.46 , pp. 534-542
    • Mai, Z.1    Blackburn, G.L.2    Zhou, J.R.3
  • 69
    • 56049126879 scopus 로고    scopus 로고
    • Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human breast cancer cells (MCF-7Ca) in vivo
    • Ju YH, Doerge DR, Woodling KA, Hartman JA, Kwak J, Helferich WG: Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human breast cancer cells (MCF-7Ca) in vivo. Carcinogenesis 2008;29:2162-2168.
    • (2008) Carcinogenesis , vol.29 , pp. 2162-2168
    • Ju, Y.H.1    Doerge, D.R.2    Woodling, K.A.3    Hartman, J.A.4    Kwak, J.5    Helferich, W.G.6
  • 70
    • 62849128454 scopus 로고    scopus 로고
    • Hanf V: Diagnosis and Treatment of Patients with Primary and Metastatic Breast Cancer: Complementary Therapy and Hormonal Treatment in Breast Cancer Survivors and (Plant) Alternatives and Survivorship, online.de/ download/g-mamma-08-1-1-c-25-complementary-therapy-hrt-survivorship.pdf. Version 2008; Arbeitsgemeinschaft Gynäkologische Onkologie, Kommission Mamma
    • Hanf V: Diagnosis and Treatment of Patients with Primary and Metastatic Breast Cancer: Complementary Therapy and Hormonal Treatment in Breast Cancer Survivors and (Plant) Alternatives and Survivorship. www.ago-online.de/ download/g-mamma-08-1-1-c-25-complementary-therapy-hrt-survivorship.pdf. Version 2008; Arbeitsgemeinschaft Gynäkologische Onkologie, Kommission Mamma.
  • 72
    • 0036714766 scopus 로고    scopus 로고
    • Adolescent and adult soy intake and risk of breast cancer in Asian-Americans
    • Wu AH, Wan P, Hankin J, Tseng CC, Yu MC, Pike MC: Adolescent and adult soy intake and risk of breast cancer in Asian-Americans. Carcinogenesis 2002;23:1491-1496.
    • (2002) Carcinogenesis , vol.23 , pp. 1491-1496
    • Wu, A.H.1    Wan, P.2    Hankin, J.3    Tseng, C.C.4    Yu, M.C.5    Pike, M.C.6
  • 75
    • 43249085452 scopus 로고    scopus 로고
    • The role of early life genistein exposures in modifying breast cancer risk
    • Warri A, Saarinen NM, Makela S, Hilakivi-Clarke L: The role of early life genistein exposures in modifying breast cancer risk. Br J Cancer 2008;98:1485-1493.
    • (2008) Br J Cancer , vol.98 , pp. 1485-1493
    • Warri, A.1    Saarinen, N.M.2    Makela, S.3    Hilakivi-Clarke, L.4
  • 78
    • 34547558889 scopus 로고    scopus 로고
    • Nutritional modulation of terminal end buds: Its relevance to breast cancer prevention
    • Hilakivi-Clarke L: Nutritional modulation of terminal end buds: its relevance to breast cancer prevention. Curr Cancer Drug Targets 2007;7:465-474.
    • (2007) Curr Cancer Drug Targets , vol.7 , pp. 465-474
    • Hilakivi-Clarke, L.1
  • 79
    • 38049041596 scopus 로고    scopus 로고
    • Soy intake and breast cancer: Elucidation of an unanswered question
    • Gammon MD, Fink BN, Steck SE, Wolff MS: Soy intake and breast cancer: elucidation of an unanswered question. Br J Cancer 2008;98:2-3.
    • (2008) Br J Cancer , vol.98 , pp. 2-3
    • Gammon, M.D.1    Fink, B.N.2    Steck, S.E.3    Wolff, M.S.4
  • 81
    • 33751158078 scopus 로고
    • Isoflavone Content in Commercial Soybean Foods
    • Wang H, Murphy PA: Isoflavone Content in Commercial Soybean Foods. J Agric Food Chem 1994;42:1666-1673.
    • (1994) J Agric Food Chem , vol.42 , pp. 1666-1673
    • Wang, H.1    Murphy, P.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.