Glucuronidation of the soyabean isoflavones genistein and daidzein by human liver is related to levels of UGT1A1 and UGT1A9 activity and alters isoflavone response in the MCF-7 human breast cancer cell line

Journal of Nutritional Biochemistry

Volumn 19, Issue 11, 2008, Pages 739-745

  Pritchett, Louise E ^a   Atherton, Kathryn M ^a   Mutch, Elaine ^b   Ford, Dianne ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Daidzein; Genistein; Isoflavone; MCF 7 cells; Phytoestrogen; UDP glucuronosyltransferase

Indexed keywords

DAIDZEIN; GENISTEIN; GLUCURONIDE; GLUCURONOSYLTRANSFERASE 1A1; GLUCURONOSYLTRANSFERASE 1A8; GLUCURONOSYLTRANSFERASE 1A9; GLYCOSYLTRANSFERASE; ISOFLAVONE;

AMINO ACID SEQUENCE; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CELL DEATH; CELL STRAIN MCF 7; CONTROLLED STUDY; DIETARY INTAKE; GLUCURONIDATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER METABOLISM; LIVER MICROSOME; METABOLIC RATE; PROTEIN FUNCTION; SOYBEAN;

ANTICARCINOGENIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; GENISTEIN; GLUCURONIDES; GLUCURONOSYLTRANSFERASE; HUMANS; ISOFLAVONES; LIVER; MODELS, CHEMICAL; PHYTOESTROGENS; SOYBEANS;

EID: 53149113807     PISSN: 09552863     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2007.10.002     Document Type: Article

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