Elastic-contractile model proteins: Physical chemistry, protein function and drug design and delivery

Advanced Drug Delivery Reviews

Volumn 62, Issue 15, 2010, Pages 1404-1455

  Urry, Dan W ^a   Urry, Kelley D ^b   Szaflarski, Witold ^b   Nowicki, Michal ^b  

^a Bioelastics Research Ltd   (United States)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Antigen binding fragments Fab1 Fab2; Drug laden nanoparticles; Elastic contractile model proteins; Elasticity of (GVGVP)n; Gibbs free energy(hydrophobic association); Multi drug resistance (MDR)

Indexed keywords

ANTIGEN BINDING; ATP SYNTHASE; CHAPERONIN; DESIGN MODIFICATIONS; DIVERSE PROTEINS; DRUG DELIVERY NANOPARTICLE; DRUG DESIGN; DRUG MODIFICATION; DRUG RELEASE; DRUG-LADEN NANOPARTICLES; ELASTIC-CONTRACTILE MODEL PROTEINS; FREE ENERGY OF HYDRATION; HUMAN CARCINOMA CELLS; HYDRATION THERMODYNAMICS; HYDROPHOBIC ASSOCIATION; LIVING ORGANISMS; MODEL PROTEINS; MULTIDRUG RESISTANCE; PHYSICOCHEMICAL PROPERTY; PROTEIN FUNCTIONS;

ANTIGENS; BIOLOGY; CHEMICAL MODIFICATION; CHEMICAL PROPERTIES; DRUG DELIVERY; ELASTICITY; FREE ENERGY; GIBBS FREE ENERGY; HYDRATION; HYDROPHOBICITY; NANOPARTICLES; PHYSICAL CHEMISTRY; POTASSIUM; PROTEINS; THERMODYNAMICS;

BINDING ENERGY;

ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; BETAMETHASONE; BIOMATERIAL; CARDIOVASCULAR AGENT; CHAPERONIN; CONTRACTILE PROTEIN; DAZMEGREL; ELASTIC CONTRACTILE MODEL PROTEIN; FARLETUZUMAB; FATTY ACID BINDING PROTEIN; GLYCOPROTEIN P; GLYCYLVALYLGLYCYLVALYLPROLINE; MULTIDRUG RESISTANCE PROTEIN 1; NANOPARTICLE; POLYPEPTIDE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANTIGEN BINDING; BIOCOMPATIBILITY; CLINICAL TRIAL; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG RELEASE; ELASTICITY; ENERGY CONVERSION; HUMAN; HYDRATION; HYDROPHOBICITY; MECHANOTRANSDUCTION; MULTIDRUG RESISTANCE; NONHUMAN; PHASE SEPARATION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION; REVIEW; TARGET CELL; THERMODYNAMICS; THERMOREGULATION; TITRIMETRY; TREATMENT OUTCOME;

ANIMALS; CHEMISTRY, PHYSICAL; CONTRACTILE PROTEINS; DRUG DELIVERY SYSTEMS; DRUG DESIGN; ELASTICITY; HUMANS; MODELS, MOLECULAR;

EID: 78649828332     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2010.07.001     Document Type: Review

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