Controlled release of phosphorothioates by protein-based polymers

Drug Delivery

Volumn 13, Issue 4, 2006, Pages 253-259

  Woods, T Cooper ^a   Urry, Dan W ^a  

^a Bioelastics Research Ltd   (United States)

Author keywords

Antisense; Elastic; Free Energy Transduction; Phosphorothioate; Protein Based Polymer

Indexed keywords

LYSINE; PHENYLALANINE; PHOSPHOROTHIOIC ACID DERIVATIVE; POLYMER;

ARTICLE; CONTROLLED RELEASE FORMULATION; ENERGY; HYDRATION; HYDROPHOBICITY; LOW TEMPERATURE; PHASE TRANSITION; PRIORITY JOURNAL; SOLUBILITY; TRANSITION TEMPERATURE;

DELAYED-ACTION PREPARATIONS; LYSINE; OLIGONUCLEOTIDES, ANTISENSE; PHENYLALANINE; PHOSPHATES; POLYMERS; RECOMBINANT PROTEINS; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSITION TEMPERATURE;

EID: 33646708284     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.1080/10717540500313075     Document Type: Article

References (26)

1. Edelman, E. R., Simons, M., Sirois, M. G., and Rosenberg, R. D. 1995. c-myc in vasculoproliferative disease. Circ. Res. 76(2):176-182.
2. Herweijer, H., and Wolff, J. A. 2003. Progress and prospects: Naked DNA gene transfer and therapy. Gene Ther. 10(6):453-458.
3. Kemppainen, B. W., D. W. Urry, S. F. Swaim, et al. 2004. Bioelastic membranes for topical application of a thromboxane synthetase inhibitor for protection of skin from pressure injury: A preliminary study. Wound Repair Regen. 12(4):453-460.
4. Khan, A. M., Benboubetra, P. Z. Sayyed, et al. 2004. Sustained polymeric delivery of gene silencing antisense ODNs, siRNA, DNAzymes and ribozymes: In vitro and in vivo studies. J. Drug Target. 12(6):393-404.
5. Luan, C. H., and Urry, D. W. 1999. Elastic, plastic, and hydrogel protein-based polymers. In Polymer Data Handbook, ed. J. E. Mark. New York: Oxford University Press.
6. Manno, M. A., Emanuele, V., Martorana, et al. 2001. Interaction of processes on different length scales in a bioelastomer capable of performing energy conversion. Biopolymers 59(1):51-64.
7. McPherson, D. T., Xu, J., and Urry, D. W. 1996. Simple product purification following expression of genes encoding up to 251 repeats of the elastomeric pentapeptide GVGVP in E. coli. Protein Exp. Purif. 7:51-57.
8. Rodriguez-Cabello, Jose, C. J., Reguera, M. Alonso, et al. 2004. Endothermic and exothermic components of an inverse temperature transition for hydrophobic association by TMDSC. Chem. Phy. Lett. 388(1-3):127-131.
9. San Biagio, Pier L., Madonia, F., Trapane, T. L., and Urry, D. W. 1988. The overlap of elastomeric polypeptide coils in solution required for single-phase initiation of elastogenesis. Chem. Phys. Lett. 145(6):571-574.
10. Sandberg, L. B., Leslie, J. G., Leach, C. T., et al. 1985. Elastin covalent structure as determined by solid phase amino acid sequencing. Pathol Biol (Paris) 33(4):266-274.
11. Sandberg, L. B., Soskel, N. T., and Leslie, J. G. 1981. Elastin structure, biosynthesis, and relation to disease states. N. Engl. J Med. 304(10):566-579.
12. Singh, M. P., Lumpkin, J. A., and Rosenblatt, J. 1995. Effect of electrostatic interactions on polylysine release rates from collagen matrices and comparison with model predictions. J. Control. Rel. 35(2-3):165-179.
13. Urry, D. W. 1993. Molecular machines: how motion and other functions of living organisms can result from reversible chemical changes. Angew. Chem. Int. Ed. Engl. 32:819-841.
14. Urry, D. W. 1997. Physical chemistry of biological free energy transduction as demonstrated by elastic protein-based polymers. J. Phys. Chem. B 101:11007-11028.
15. Urry, D.W., Harris, C. M., Luan, C. X., et al. 1997. Transductional protein-based polymers as new controlled release vehicles. Part VI: New biomaterials for drug delivery. In Controlled Drug Delivery: Challenges and Strategies, ed. K. Park. Washington, DC: Am. Chem. Soc. Professional Reference Book.
16. Urry, D. W., McPherson, D. T., Xu, J., Channe-Gowda, D., and Parker, T. M. 1995. Elastic and plastic protein-based polymers: potential for industrial uses. In Industrial Biotechnological Polymers, eds. C. Gebelein and C. E. Carraher Jr. Lancaster, PA: Technomic Publishing Co.
17. Urry, D. W., Nicol, A., McPherson, D. T., et al. 1995. Properties, preparations and applications of bioelastic materials. In Encyclopedic Handbook of Biomaterials and Bioengineering - Part A - Materials, vol. 2. New York: Marcel Dekker.
18. Urry, D. W., Parker, T. M., Reid, M. C., and Channe-Gowda, D. 1991. Biocompatibility of the bioelastic materials, poly(gvgvp) and its gamma-irradiation cross-linked matrix: summary of generic biological test results. J. Bioactive Compatible Polym. 6:263-282.
19. Urry, D. W., Pattanaik, A., Accavitti, M. A., et al. 1997. Transductional elastic and plastic protein-based polymers as potential medical devices. In Handbook of Biodegradable Polymers, eds. Domb, Kost, and Wiseman. Chur, Switzerland: Harwood Academic Publishers.
20. Urry, D. W., Pattanaik, A., Xu, J., et al. 1998. Elastic protein-based polymers in soft tissue augmentation and generation. J. Biomater. Sci. Polymer Edn. 9:1015-1048.
21. Urry, D. W., Peng, S. Q., Channe-Gowda, D., Parker, T. M., and Harris, R. D. 1994. Comparison of electrostatic- and hydrophobic-induced pka shifts in polypentapeptides: the lysine residue. Chem. Phys. Ltrs. 225:97-103.
22. Urry, D. W., Peng, S. Q., Xu, J., and McPherson, D. T. 1997. Characterization of waters of hydrophobic hydration by microwave dielectric relaxation. JACS 119:1161-1162.
23. Urry, D. W. 2004. The change in Gibbs free energy for hydrophobic association - derivation and evaluation by means of inverse temperature transitions. Chem. Phys. Lett. 399(1-3):177-183.
24. Urry, D. W., Woods, T. C., Hayes, L. C., et al. 2004. Elastic protein-based biomaterials: elements of basic science, controlled release and biocompatibility. In Tissue Engineering and Novel Delivery Systems. New York: Marcel Dekker.
25. Wang, N. Z., Urry, D. W., Swaim, S. F., et al. 2004. Skin concentrations of thromboxane synthetase inhibitor after topical application with bioelastic membrane. J. Vet. Pharmacol. Ther. 27(1):37-43.
26. Yeh, H., Ornstein-Goldstein, N., Indik, Z., et al. 1987. Sequence variation of bovine elastin mRNA due to alternative splicing. Coll. Relat. Res. 7(4):235-247.