Metformin and exercise reduce muscle FAT/CD36 and lipid accumulation and blunt the progression of high-fat diet-induced hyperglycemia

American Journal of Physiology - Endocrinology and Metabolism

Volumn 293, Issue 1, 2007, Pages

  Smith, Angela C ^a   Mullen, Kerry L ^a   Junkin, Kathryn A ^a   Nickerson, Jennifer ^a   Chabowski, Adrian ^b   Bonen, Arend ^a   Dyck, David J ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

Adenosine 5 monophosphate activated protein kinase; Ceramide; Diacylglycerol; Glucose transport; Lipid metabolism; Zucker diabetic fatty rat

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; CD36 ANTIGEN; CERAMIDE; CITRATE SYNTHASE; GLUCOSE; INSULIN; METFORMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRIACYLGLYCEROL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE COURSE; DRUG MECHANISM; ENZYME ACTIVITY; FATTY ACID METABOLISM; FATTY ACID OXIDATION; FEMALE; GLUCOSE TRANSPORT; HYPERGLYCEMIA; HYPERINSULINEMIA; INSULIN RESISTANCE; LIPID DIET; LIPID STORAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKELETAL MUSCLE; TREADMILL EXERCISE; ZUCKER DIABETIC FATTY RAT;

ANIMALS; ANTIGENS, CD36; BODY COMPOSITION; DIET, ATHEROGENIC; DISEASE PROGRESSION; FEMALE; GLUCOSE; GLUCOSE TRANSPORTER TYPE 4; HYPERGLYCEMIA; HYPOGLYCEMIC AGENTS; INSULIN; LIPID METABOLISM; LIPIDS; METFORMIN; MUSCLE, SKELETAL; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, ZUCKER; RECEPTORS, LIPOPROTEIN;

EID: 34547131281     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00677.2006     Document Type: Article

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