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Volumn 15, Issue 6, 2010, Pages 751-756

CD8+ regulatory T cells in solid organ transplantation

Author keywords

CD8 regulatory T cells; tolerance; transplantation

Indexed keywords

BIOLOGICAL MARKER; PERFORIN; T LYMPHOCYTE RECEPTOR;

EID: 78649637232     PISSN: 10872418     EISSN: 15317013     Source Type: Journal    
DOI: 10.1097/MOT.0b013e32834016d1     Document Type: Review
Times cited : (31)

References (80)
  • 1
    • 0014792798 scopus 로고
    • Cell interactions in the induction oftolerance: The role ofthymic lymphocytes
    • Gershon RK, Kondo K. Cell interactions in the induction oftolerance: the role ofthymic lymphocytes. Immunology 1970; 18:723-737.
    • (1970) Immunology , vol.18 , pp. 723-737
    • Gershon, R.K.1    Kondo, K.2
  • 2
    • 0017111730 scopus 로고
    • Separation ofhelperTcellsfromsuppressor T cells expressing different Ly components. II: Activation by antigen: After immunization, antigen-specific suppressor and helper activities are mediated by distinct T-cell subclasses
    • Cantor H,Shen FW, Boyse EA. Separation ofhelperTcellsfromsuppressor T cells expressing different Ly components. II: Activation by antigen: after immunization, antigen-specific suppressor and helper activities are mediated by distinct T-cell subclasses. J Exp Med 1976; 143:1391-1440.
    • (1976) J Exp Med , vol.143 , pp. 1391-1440
    • Cantor Hshen, F.W.1    Boyse, E.A.2
  • 3
    • 14844365222 scopus 로고    scopus 로고
    • The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen
    • Bushell A, Jones E, Gallimore A, et al. The generation of CD25+ CD4+ regulatory T cells that prevent allograft rejection does not compromise immunity to a viral pathogen. J Immunol 2005; 174:3290-3297.
    • (2005) J Immunol , vol.174 , pp. 3290-3297
    • Bushell, A.1    Jones, E.2    Gallimore, A.3
  • 5
    • 70349339392 scopus 로고    scopus 로고
    • Efficient induction and expansion of human alloantigen-specific CD8 regulatory T cells from naive precursors by CD40-activated B cells
    • Zheng J, Liu Y, Qin G, et al. Efficient induction and expansion of human alloantigen-specific CD8 regulatory T cells from naive precursors by CD40-activated B cells. J Immunol 2009; 183:3742-3750.
    • (2009) J Immunol , vol.183 , pp. 3742-3750
    • Zheng, J.1    Liu, Y.2    Qin, G.3
  • 6
    • 43649096023 scopus 로고    scopus 로고
    • + regulatory T cells by continuous antigen stimulation
    • + regulatory T cells by continuous antigen stimulation. Eur J Immunol 2008; 38:640-646.
    • (2008) Eur J Immunol , vol.38 , pp. 640-646
    • Mahic, M.1    Henjum, K.2    Yaqub, S.3
  • 7
    • 0030472309 scopus 로고    scopus 로고
    • Allospecific CD8+ Tc1 and Tc2 populations in graft-versus-leukemia effect and graft-versus-host disease
    • Fowler DH, Breglio J, Nagel G, et al. Allospecific CD8+ Tc1 and Tc2 populations in graft-versus-leukemia effect and graft-versus-host disease. J Immunol 1996; 157:4811-4821.
    • (1996) J Immunol , vol.157 , pp. 4811-4821
    • Fowler, D.H.1    Breglio, J.2    Nagel, G.3
  • 8
    • 0027294049 scopus 로고
    • Donor CD8 cells prevent allogeneic marrow graft rejection in mice: Potential implicationsfor marrowtransplantation in humans
    • Martin PJ. Donor CD8 cells prevent allogeneic marrow graft rejection in mice: potential implicationsfor marrowtransplantation in humans. J Exp Med 1993; 178:703-712.
    • (1993) J Exp Med , vol.178 , pp. 703-712
    • Martin, P.J.1
  • 9
    • 85047690427 scopus 로고    scopus 로고
    • Regulatoryfunctions ofCD8+CD28? T cells in an autoimmune disease model
    • Najafian N, Chitnis T, Salama A D, et al. Regulatoryfunctions ofCD8+CD28? T cells in an autoimmune disease model. J Clin Invest 2003; 112:1037-1048.
    • (2003) J Clin Invest , vol.112 , pp. 1037-1048
    • Najafian, N.1    Chitnis, T.2    Salama, A.D.3
  • 10
    • 2442675275 scopus 로고    scopus 로고
    • Analysisofregulatory C D8Tcellsin Qa-1-deficient mice
    • Hu D, Ikizawa K, Lu L, et al. Analysisofregulatory C D8Tcellsin Qa-1-deficient mice. Nat Immunol 2004; 5:516-523.
    • (2004) Nat Immunol , vol.5 , pp. 516-523
    • Hu, D.1    Ikizawa, K.2    Lu, L.3
  • 12
    • 85047690562 scopus 로고    scopus 로고
    • Qa-1 restriction of CD8+ suppressor T cells
    • Sarantopoulos S, Lu L, Cantor H. Qa-1 restriction of CD8+ suppressor T cells. J Clin Invest 2004; 114:1218-1221.
    • (2004) J Clin Invest , vol.114 , pp. 1218-1221
    • Sarantopoulos, S.1    Lu, L.2    Cantor, H.3
  • 13
    • 21244433093 scopus 로고    scopus 로고
    • Peripheral CD8+CD25+ T lympho-cytes from MHC class II-deficient mice exhibit regulatory activity
    • Bienvenu B, Martin B, Auffray C, et al. Peripheral CD8+CD25+ T lympho-cytes from MHC class II-deficient mice exhibit regulatory activity. J Immunol 2005; 175:246-253.
    • (2005) J Immunol , vol.175 , pp. 246-253
    • Bienvenu, B.1    Martin, B.2    Auffray, C.3
  • 14
    • 57649099846 scopus 로고    scopus 로고
    • CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype?
    • Aandahl EM, Torgersen KM, Tasken K. CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype? Hum Immunol 2008; 69:696-699.
    • (2008) Hum Immunol , vol.69 , pp. 696-699
    • Aandahl, E.M.1    Torgersen, K.M.2    Tasken, K.3
  • 15
    • 25844504653 scopus 로고    scopus 로고
    • Developmental regulation of Foxp3 expression during ontogeny
    • Fontenot JD, Dooley JL, Farr AG, et al. Developmental regulation of Foxp3 expression during ontogeny. J Exp Med 2005; 202:901-906.
    • (2005) J Exp Med , vol.202 , pp. 901-906
    • Fontenot, J.D.1    Dooley, J.L.2    Farr, A.G.3
  • 16
    • 15244354286 scopus 로고    scopus 로고
    • Regulatory T cell lineage specification by the forkhead transcription factor foxp3
    • Fontenot JD, Rasmussen JP, Williams LM, et al. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 2005; 22:329-341.
    • (2005) Immunity , vol.22 , pp. 329-341
    • Fontenot, J.D.1    Rasmussen, J.P.2    Williams, L.M.3
  • 17
    • 65349124769 scopus 로고    scopus 로고
    • CD45RC isoform expression identifies functionally distinct T cell subsets differentially distributed between healthy individuals and AAV patients
    • Ordonez L, Bernard I, L'Faqihi-Olive FE, et al. CD45RC isoform expression identifies functionally distinct T cell subsets differentially distributed between healthy individuals and AAV patients. PLo S One 2009; 4:e5287.
    • (2009) PLoS One , vol.4
    • Ordonez, L.1    Bernard, I.2    L'Faqihi-Olive, F.E.3
  • 18
    • 4344655347 scopus 로고    scopus 로고
    • Functional and genetic analysis of two CD8 T cell subsets defined by the level of CD45RC expression in the rat
    • Xystrakis E, Cavailles P, Dejean AS, et al. Functional and genetic analysis of two CD8 T cell subsets defined by the level of CD45RC expression in the rat. J Immunol 2004; 173:3140-3147.
    • (2004) J Immunol , vol.173 , pp. 3140-3147
    • Xystrakis, E.1    Cavailles, P.2    Dejean, A.S.3
  • 19
    • 33845748319 scopus 로고    scopus 로고
    • CD8+CD28\regulatory T lymphocytes prevent experimental inflammatory bowel disease in mice
    • Menager-Marcq I, Pomie C, Romagnoli P, et al. CD8+CD28\regulatory T lymphocytes prevent experimental inflammatory bowel disease in mice. Gas-troenterology 2006; 131:1775-1785.
    • (2006) Gas-troenterology , vol.131 , pp. 1775-1785
    • Menager-Marcq, I.1    Pomie, C.2    Romagnoli, P.3
  • 20
    • 42149164952 scopus 로고    scopus 로고
    • A CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis
    • Ho J, Kurtz CC, Naganuma M, et al. A CD8+/CD103high T cell subset regulates TNF-mediated chronic murine ileitis. J Immunol 2008; 180:2573-2580.
    • (2008) J Immunol , vol.180 , pp. 2573-2580
    • Ho, J.1    Kurtz, C.C.2    Naganuma, M.3
  • 21
    • 8644249136 scopus 로고    scopus 로고
    • Essential roles of CD8+CD122+ regulatoryT cells in the maintenance of T cell homeostasis
    • Rifa'i M, Kawamoto Y, Nakashima I, et al. Essential roles of CD8+CD122+ regulatoryT cells in the maintenance of T cell homeostasis. J Exp Med 2004; 200:1123-1134.
    • (2004) J Exp Med , vol.200 , pp. 1123-1134
    • Rifa'I, M.1    Kawamoto, Y.2    Nakashima, I.3
  • 22
    • 28244441236 scopus 로고    scopus 로고
    • Cutting edge: CD8+CD122+ regulatory T cells produce IL-10 to suppress IFN-gamma production and proliferation of CD8+ T cells
    • Endharti AT, Rifa IM, Shi Z, et al. Cutting edge: CD8+CD122+ regulatory T cells produce IL-10 to suppress IFN-gamma production and proliferation of CD8+ T cells. J Immunol 2005; 175:7093-7097.
    • (2005) J Immunol , vol.175 , pp. 7093-7097
    • Endharti, A.T.1    Rifa, I.M.2    Shi, Z.3
  • 23
    • 44449127238 scopus 로고    scopus 로고
    • Preferential development of CD4 and CD8 T regulatory cells in RasGR P1-deficient mice
    • Chen X, Priatel JJ, Chow MT, et al. Preferential development of CD4 and CD8 T regulatory cells in RasGR P1-deficient mice. J Immunol 2008; 180:5973-5982.
    • (2008) J Immunol , vol.180 , pp. 5973-5982
    • Chen, X.1    Priatel, J.J.2    Chow, M.T.3
  • 24
    • 77955477831 scopus 로고    scopus 로고
    • Cutting edge: Programmed death-1 defines CD8+CD122+Tcellsas regulatory versus memoryTcells
    • Dai H, Wan N, Zhang S, et al. Cutting edge: programmed death-1 defines CD8+CD122+Tcellsas regulatory versus memoryTcells. J Immunol 2010; 185:803-807.
    • (2010) J Immunol , vol.185 , pp. 803-807
    • Dai, H.1    Wan, N.2    Zhang, S.3
  • 25
    • 54049098297 scopus 로고    scopus 로고
    • PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue
    • Koehn BH, Ford ML, Ferrer IR, et al. PD-1-dependent mechanisms maintain peripheral tolerance of donor-reactive CD8+ T cells to transplanted tissue. J Immunol 2008; 181:5313-5322.
    • (2008) J Immunol , vol.181 , pp. 5313-5322
    • Koehn, B.H.1    Ford, M.L.2    Ferrer, I.R.3
  • 26
    • 52649129667 scopus 로고    scopus 로고
    • Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway
    • Haspot F, Fehr T, Gibbons C, et al. Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway. Blood 2008; 112:2149-2155.
    • (2008) Blood , vol.112 , pp. 2149-2155
    • Haspot, F.1    Fehr, T.2    Gibbons, C.3
  • 27
    • 7044261952 scopus 로고    scopus 로고
    • 4-1BB-mediated immunotherapy of rheu-matoid arthritis
    • Seo SK, Choi JH, Kim YH, et al. 4-1BB-mediated immunotherapy of rheu-matoid arthritis. Nat Med 2004; 10:1088-1094.
    • (2004) Nat Med , vol.10 , pp. 1088-1094
    • Seo, S.K.1    Choi, J.H.2    Kim, Y.H.3
  • 28
    • 62449321765 scopus 로고    scopus 로고
    • Generation and regulation of CD8(+) regulatory T cells
    • Lu L, Cantor H. Generation and regulation of CD8(+) regulatory T cells. Cell Mol Immunol 2008; 5:401-406.
    • (2008) Cell Mol Immunol , vol.5 , pp. 401-406
    • Lu, L.1    Cantor, H.2
  • 29
    • 0035470836 scopus 로고    scopus 로고
    • Induction ofTCRVbeta-specific CD8+ CTLs by TCR Vbeta-derived peptides bound to HLA-E
    • Li J, Goldstein I, Glickman-Nir E, et al. Induction ofTCRVbeta-specific CD8+ CTLs by TCR Vbeta-derived peptides bound to HLA-E. J Immunol 2001; 167:3800-3808.
    • (2001) J Immunol , vol.167 , pp. 3800-3808
    • Li, J.1    Goldstein, I.2    Glickman-Nir, E.3
  • 30
    • 77953635469 scopus 로고    scopus 로고
    • Controlof Tcell reactivation by regulatory Qa-1-restricted CD8+ T cells
    • Varthaman A, Khallou-Laschet J,Clement M, et al.Controlof Tcell reactivation by regulatory Qa-1-restricted CD8+ T cells. J Immunol 2010.
    • (2010) J Immunol
    • Varthaman, A.1    Khallou-Laschet, J.2    Clement, M.3
  • 31
    • 34147112868 scopus 로고    scopus 로고
    • CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase
    • Guillonneau C, Hill M, Hubert FX, et al. CD40Ig treatment results in allograft acceptance mediated by CD8CD45RC T cells, IFN-gamma, and indoleamine 2,3-dioxygenase. J Clin Invest 2007; 117:1096-1106.
    • (2007) J Clin Invest , vol.117 , pp. 1096-1106
    • Guillonneau, C.1    Hill, M.2    Hubert, F.X.3
  • 32
    • 8644240281 scopus 로고    scopus 로고
    • Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation
    • Xystrakis E, Dejean AS, Bernard I, et al. Identification of a novel natural regulatory CD8 T-cell subset and analysis of its mechanism of regulation. Blood 2004; 104:3294-3301.
    • (2004) Blood , vol.104 , pp. 3294-3301
    • Xystrakis, E.1    Dejean, A.S.2    Bernard, I.3
  • 33
    • 4544227160 scopus 로고    scopus 로고
    • Role of regulatory and suppressor T-cells in the induction of ILT3+ ILT4+ tolerogenic endothelial cells in organ allografts
    • Cortesini NS, Colovai AI, Manavalan JS, et al. Role of regulatory and suppressor T-cells in the induction of ILT3+ ILT4+ tolerogenic endothelial cells in organ allografts. Transpl Immunol 2004; 13:73-82.
    • (2004) Transpl Immunol , vol.13 , pp. 73-82
    • Cortesini, N.S.1    Colovai, A.I.2    Manavalan, J.S.3
  • 34
    • 20844457916 scopus 로고    scopus 로고
    • Rat CD8+ FOXP3+ T suppressor cells mediate tolerance to allogeneic heart transplants, inducing PIR-B in APC and rendering the graft invulnerable to rejection
    • Liu J, Liu Z, Witkowski P, et al. Rat CD8+ FOXP3+ T suppressor cells mediate tolerance to allogeneic heart transplants, inducing PIR-B in APC and rendering the graft invulnerable to rejection. Transpl Immunol 2004; 13:239-247.
    • (2004) Transpl Immunol , vol.13 , pp. 239-247
    • Liu, J.1    Liu, Z.2    Witkowski, P.3
  • 35
    • 77949886577 scopus 로고    scopus 로고
    • Characterization of rabbit antithymocyte globulins-induced CD25+ regulatory T cells from cells of patients with end-stage renal disease
    • Sewgobind VD, van der Laan LJ, Kho MM, et al. Characterization of rabbit antithymocyte globulins-induced CD25+ regulatory T cells from cells of patients with end-stage renal disease. Transplantation 2010; 89:655-666.
    • (2010) Transplantation , vol.89 , pp. 655-666
    • Sewgobind, V.D.1    Van Der Laan, L.J.2    Kho, M.M.3
  • 36
    • 33750207379 scopus 로고    scopus 로고
    • TCRtransgenic CD8+T cells activated in the presence of TGFbeta express Fox P3 and mediate linked suppression of primary immune responses and cardiac allograft rejection
    • Kapp JA, Honjo K, Kapp LM, et al. TCRtransgenic CD8+T cells activated in the presence of TGFbeta express Fox P3 and mediate linked suppression of primary immune responses and cardiac allograft rejection. Int Immunol 2006; 18:1549-1562.
    • (2006) Int Immunol , vol.18 , pp. 1549-1562
    • Kapp, J.A.1    Honjo, K.2    Kapp, L.M.3
  • 37
    • 45449091784 scopus 로고    scopus 로고
    • CD8+ gammadelta T regulatory cells mediate kidney allograft prolongation after oral exposure to alloantigen
    • Zhou J, Appleton SE, Stadnyk A, et al. CD8+ gammadelta T regulatory cells mediate kidney allograft prolongation after oral exposure to alloantigen. Transpl Int 2008; 21:679-687.
    • (2008) Transpl Int , vol.21 , pp. 679-687
    • Zhou, J.1    Appleton, S.E.2    Stadnyk, A.3
  • 38
    • 67650091395 scopus 로고    scopus 로고
    • A continuous infusion of a minor histocompatibility antigen- immunodominant peptide induces a delay of male skin graft rejection
    • Sireci G, Barera A, Macaluso P, et al. A continuous infusion of a minor histocompatibility antigen-immunodominant peptide induces a delay of male skin graft rejection. Immunobiology 2009; 214:703-711.
    • (2009) Immunobiology , vol.214 , pp. 703-711
    • Sireci, G.1    Barera, A.2    MacAluso, P.3
  • 39
    • 58149330290 scopus 로고    scopus 로고
    • The FGL2-FcgammaRII B pathway: A novel mechanism leading to immunosuppression
    • Liu H, Shalev I, Manuel J, et al. The FGL2-FcgammaRII B pathway: a novel mechanism leading to immunosuppression. Eur J Immunol 2008; 38:3114-3126.
    • (2008) Eur J Immunol , vol.38 , pp. 3114-3126
    • Liu, H.1    Shalev, I.2    Manuel, J.3
  • 40
    • 40149102880 scopus 로고    scopus 로고
    • Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis
    • Shalev I, Liu H, Koscik C, et al. Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis. J Immunol 2008; 180:249-260.
    • (2008) J Immunol , vol.180 , pp. 249-260
    • Shalev, I.1    Liu, H.2    Koscik, C.3
  • 41
    • 77955498050 scopus 로고    scopus 로고
    • Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance
    • Li XL, Menoret S, Bezie S, et al. Mechanism and localization of CD8 regulatory T cells in a heart transplant model of tolerance. J Immunol 2010.
    • (2010) J Immunol
    • Li, X.L.1    Menoret Bezie S, S.2
  • 42
    • 45749145836 scopus 로고    scopus 로고
    • CD8+CD122+ regulatory T cells recognize activated T cells via conventional MHC class I-alphabetaTCR interaction and become IL-10-producing active regulatory cells
    • Rifa'i M, Shi Z, Zhang SY, et al. CD8+CD122+ regulatory T cells recognize activated T cells via conventional MHC class I-alphabetaTCR interaction and become IL-10-producing active regulatory cells. Int Immunol 2008; 20:937-947.
    • (2008) Int Immunol , vol.20 , pp. 937-947
    • Rifa'I, M.1    Shi, Z.2    Zhang, S.Y.3
  • 43
    • 42149173305 scopus 로고    scopus 로고
    • Importance ofCD80/CD86-CD28 interactions in the recognition of target cells by CD8+CD122+ regulatory T cells
    • Shi Z, Rifa'i M, Lee Y H, et al. Importance ofCD80/CD86-CD28 interactions in the recognition of target cells by CD8+CD122+ regulatory T cells. Immunology 2008; 124:121-128.
    • (2008) Immunology , vol.124 , pp. 121-128
    • Shi, Z.1    Rifa'I, M.2    Lee, Y.H.3
  • 44
    • 40049105939 scopus 로고    scopus 로고
    • Anti-CD28 antibodies modify regulatory mechanisms and reinforce tolerance in CD40Ig-treated heart allograft recipients
    • Guillonneau C, Seveno C, Dugast AS, et al. Anti-CD28 antibodies modify regulatory mechanisms and reinforce tolerance in CD40Ig-treated heart allograft recipients. J Immunol 2007; 179:8164-8171.
    • (2007) J Immunol , vol.179 , pp. 8164-8171
    • Guillonneau, C.1    Seveno, C.2    Dugast, A.S.3
  • 45
    • 34548809817 scopus 로고    scopus 로고
    • A novel alloantigen-specific CD8+PD1 + regulatory T cell induced by ICOS-B7h blockade in vivo
    • Izawa A, Yamaura K,Albin MJ, et al. A novel alloantigen-specific CD8+PD1 + regulatory T cell induced by ICOS-B7h blockade in vivo. J Immunol 2007; 179:786-796.
    • (2007) J Immunol , vol.179 , pp. 786-796
    • Izawa, A.1    Yamaura Kalbin, M.J.2
  • 46
    • 70249127941 scopus 로고    scopus 로고
    • Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg
    • Shi Z, Okuno Y, Rifa'i M, et al. Human CD8+CXCR3+ T cells have the same function as murine CD8+CD122+ Treg. Eur J Immunol 2009; 39:2106-2119.
    • (2009) Eur J Immunol , vol.39 , pp. 2106-2119
    • Shi, Z.1    Okuno Rifa'I Y, M.2
  • 47
    • 58049220247 scopus 로고    scopus 로고
    • Regulation of CD8+ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease
    • Lu L, Kim HJ, Werneck MB, et al. Regulation of CD8+ regulatory T cells: interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease. Proc Natl Acad Sci USA 2008; 105:19420-19425.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 19420-19425
    • Lu, L.1    Kim, H.J.2    Werneck, M.B.3
  • 48
    • 34248589088 scopus 로고    scopus 로고
    • Regulation ofactivated CD4+T cells by NKcells via the Qa-1-NKG2A inhibitory pathway
    • Lu L, Ikizawa K, Hu D, et al. Regulation ofactivated CD4+T cells by NKcells via the Qa-1-NKG2A inhibitory pathway. Immunity 2007; 26:593-604.
    • (2007) Immunity , vol.26 , pp. 593-604
    • Lu, L.1    Ikizawa, K.2    Hu, D.3
  • 49
    • 77952540031 scopus 로고    scopus 로고
    • Mechanisms of immune suppression for CD8+ T cells by human corneal endothelial cells via membrane-bound TGFbeta
    • Yamada Y, Sugita S, Horie S, et al. Mechanisms of immune suppression for CD8+ T cells by human corneal endothelial cells via membrane-bound TGFbeta. Invest Ophthalmol Vis Sci 2010; 51:2548-2557.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 2548-2557
    • Yamada, Y.1    Sugita, S.2    Horie, S.3
  • 50
    • 47349131223 scopus 로고    scopus 로고
    • Prolongation of corneal xenotransplant survival by T-cell vaccination-induced T-regulatory cells
    • Wang J, Jiang S, Shi H, et al. Prolongation of corneal xenotransplant survival by T-cell vaccination-induced T-regulatory cells. Xenotransplantation 2008; 15:164-173.
    • (2008) Xenotransplantation , vol.15 , pp. 164-173
    • Wang, J.1    Jiang, S.2    Shi, H.3
  • 51
    • 59449093511 scopus 로고    scopus 로고
    • Accumulation of autoreactive effector T cells and allo-specific regulatory T cells in the pancreasallo graft of a type 1 diabetic recipient
    • Velthuis JH, Unger WW, van der Slik A R, et al. Accumulation of autoreactive effector T cells and allo-specific regulatory T cells in the pancreasallo graft of a type 1 diabetic recipient. Diabetologia 2009; 52:494-503.
    • (2009) Diabetologia , vol.52 , pp. 494-503
    • Velthuis, J.H.1    Unger, W.W.2    Van Der Slik, A.R.3
  • 52
    • 58749086409 scopus 로고    scopus 로고
    • Alloantigen-induced regulatory CD8+CD103+ T cells
    • Koch SD, Uss E, van Lier RA, et al. Alloantigen-induced regulatory CD8+CD103+ T cells. Hum Immunol 2008; 69:737-744.
    • (2008) Hum Immunol , vol.69 , pp. 737-744
    • Koch, S.D.1    Uss, E.2    Van Lier, R.A.3
  • 53
    • 34247503135 scopus 로고    scopus 로고
    • Rapamycin enhances the number of alloantigen-induced human CD103+CD8+ regulatory T cells in vitro
    • Uss E, Yong SL, Hooibrink B, et al. Rapamycin enhances the number of alloantigen-induced human CD103+CD8+ regulatory T cells in vitro. Trans-plantation 2007; 83:1098-1106.
    • (2007) Trans-plantation , vol.83 , pp. 1098-1106
    • Uss, E.1    Yong, S.L.2    Hooibrink, B.3
  • 54
    • 63549098516 scopus 로고    scopus 로고
    • + regulatory T cells in spontaneous tolerance of liver allografts
    • + regulatory T cells in spontaneous tolerance of liver allografts. Int Immunopharmacol 2009; 9:546-548.
    • (2009) Int Immunopharmacol , vol.9 , pp. 546-548
    • Lu, L.1    Yu, Y.2    Li, G.3
  • 55
    • 77949536177 scopus 로고    scopus 로고
    • A CD8 Tcell-intrinsic roleforthe calcineurin-NFAT pathway for tolerance induction in vivo
    • Fehr T, Lucas CL, Kurtz J, et al.A CD8 Tcell-intrinsic roleforthe calcineurin-NFAT pathway for tolerance induction in vivo. Blood 2010; 115:1280-1287.
    • (2010) Blood , vol.115 , pp. 1280-1287
    • Fehr, T.1    Lucas, C.L.2    Kurtz, J.3
  • 56
    • 20344377957 scopus 로고    scopus 로고
    • The role of TCR specificity in naturally arising CD25+ CD4+ regulatory T cell biology
    • Hsieh CS, Rudensky AY. The role of TCR specificity in naturally arising CD25+ CD4+ regulatory T cell biology. Curr Top Microbiol Immunol 2005; 293:25-42.
    • (2005) Curr Top Microbiol Immunol , vol.293 , pp. 25-42
    • Hsieh, C.S.1    Rudensky, A.Y.2
  • 57
    • 65549100376 scopus 로고    scopus 로고
    • Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1
    • Josefowicz SZ, Wilson CB, Rudensky AY. Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1. J Immunol 2009; 182:6648-6652.
    • (2009) J Immunol , vol.182 , pp. 6648-6652
    • Josefowicz, S.Z.1    Wilson, C.B.2    Rudensky, A.Y.3
  • 58
    • 58849093999 scopus 로고    scopus 로고
    • The specificity of T cell regulation that enables self-nonself discrimination in the periphery
    • Wu Y, Zheng Z, Jiang Y, et al. The specificity of T cell regulation that enables self-nonself discrimination in the periphery. Proc Natl Acad Sci USA 2009; 106:534-539.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 534-539
    • Wu, Y.1    Zheng, Z.2    Jiang, Y.3
  • 59
    • 57649083400 scopus 로고    scopus 로고
    • Qa-1/HLA-E-restricted regulatory CD8+ T cells and self- nonselfdiscrimination: An essay on peripheralT-cell regulation
    • Jiang H, Chess L. Qa-1/HLA-E-restricted regulatory CD8+ T cells and self-nonselfdiscrimination: an essay on peripheralT-cell regulation. Hum Immunol 2008; 69:721-727.
    • (2008) Hum Immunol , vol.69 , pp. 721-727
    • Jiang, H.1    Chess, L.2
  • 60
    • 57649085061 scopus 로고    scopus 로고
    • Human CD8+ T-regulatory cells with low-avidity T-cell receptor specific for minor histocompatibility antigens
    • Burlingham WJ, Goulmy E. Human CD8+ T-regulatory cells with low-avidity T-cell receptor specific for minor histocompatibility antigens. Hum Immunol 2008; 69:728-731.
    • (2008) Hum Immunol , vol.69 , pp. 728-731
    • Burlingham, W.J.1    Goulmy, E.2
  • 61
    • 26444515022 scopus 로고    scopus 로고
    • TCRstimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs
    • Bisikirska B, Colgan J, Luban J, et al. TCRstimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs. J Clin Invest 2005; 115:2904-2913.
    • (2005) J Clin Invest , vol.115 , pp. 2904-2913
    • Bisikirska, B.1    Colgan, J.2    Luban, J.3
  • 62
    • 59649118664 scopus 로고    scopus 로고
    • Antigen-specific peripheral shaping of the natural regulatory T cell population
    • Lathrop SK, Santacruz NA, Pham D, et al. Antigen-specific peripheral shaping of the natural regulatory T cell population. J Exp Med 2008; 205:3105-3117.
    • (2008) J Exp Med , vol.205 , pp. 3105-3117
    • Lathrop, S.K.1    Santacruz, N.A.2    Pham, D.3
  • 63
    • 34848864537 scopus 로고    scopus 로고
    • Antigen, in the presence of TGF-beta, induces up-regulation of Fox P3gfp+ in CD4+ TCR transgenic T cells that mediate linked suppression of CD8+ T cell responses
    • Kapp JA, Honjo K, Kapp LM, et al. Antigen, in the presence of TGF-beta, induces up-regulation of Fox P3gfp+ in CD4+ TCR transgenic T cells that mediate linked suppression of CD8+ T cell responses. J Immunol 2007; 179:2105-2114.
    • (2007) J Immunol , vol.179 , pp. 2105-2114
    • Kapp, J.A.1    Honjo, K.2    Kapp, L.M.3
  • 64
    • 57649101657 scopus 로고    scopus 로고
    • CD8+ suppressor T cells resurrected
    • Kapp JA, Bucy RP. CD8+ suppressor T cells resurrected. Hum Immunol 2008; 69:715-720.
    • (2008) Hum Immunol , vol.69 , pp. 715-720
    • Kapp, J.A.1    Bucy, R.P.2
  • 65
    • 32644459908 scopus 로고    scopus 로고
    • Antigen-specific regulatory T cells: Ex vivo expansion and therapeutic potential
    • Masteller EL, Tang Q, Bluestone JA. Antigen-specific regulatory T cells: ex vivo expansion and therapeutic potential. Semin Immunol 2006; 18:103-110.
    • (2006) Semin Immunol , vol.18 , pp. 103-110
    • Masteller, E.L.1    Tang, Q.2    Bluestone, J.A.3
  • 66
    • 44849118898 scopus 로고    scopus 로고
    • Clinical application of regulatoryTcellsfortreatmentof type 1 diabetes and transplantation
    • Brusko T, Bluestone J. Clinical application of regulatoryTcellsfortreatmentof type 1 diabetes and transplantation. Eur J Immunol 2008; 38:931-934.
    • (2008) Eur J Immunol , vol.38 , pp. 931-934
    • Brusko, T.1    Bluestone, J.2
  • 67
    • 34147130293 scopus 로고    scopus 로고
    • Yin and yang interplay of IFN-gamma in inflammation and auto-immune disease
    • Zhang J. Yin and yang interplay of IFN-gamma in inflammation and auto-immune disease. J Clin Invest 2007; 117:871-873.
    • (2007) J Clin Invest , vol.117 , pp. 871-873
    • Zhang, J.1
  • 68
    • 71249132533 scopus 로고    scopus 로고
    • A significant expansion of CD8+ CD28-T-suppressor cells in adult-to-adult living donor liver transplant recipients
    • Lin YX, Yan LN, Li B, et al. A significant expansion of CD8+ CD28-T-suppressor cells in adult-to-adult living donor liver transplant recipients. Transplant Proc 2009; 41:4229-4231.
    • (2009) Transplant Proc , vol.41 , pp. 4229-4231
    • Lin, Y.X.1    Yan, L.N.2    Li, B.3
  • 69
    • 67549089794 scopus 로고    scopus 로고
    • Analysis ofCD8+CD28? T-suppressorcells in living donor livertransplant recipients
    • Lin YX, Wang LL, Yan LN, et al. Analysis ofCD8+CD28? T-suppressorcells in living donor livertransplant recipients. Hepatobiliary Pancreat Dis Int 2009; 8:241-246.
    • (2009) Hepatobiliary Pancreat Dis Int , vol.8 , pp. 241-246
    • Lin, Y.X.1    Wang, L.L.2    Yan, L.N.3
  • 70
    • 33644502542 scopus 로고    scopus 로고
    • Recombinant Ig-like transcript 3-Fc modulates T cell responses via induction of Th anergy and differentiation of CD8+ T suppressor cells
    • Kim-Schulze S, Scotto L, Vlad G, et al. Recombinant Ig-like transcript 3-Fc modulates T cell responses via induction of Th anergy and differentiation of CD8+ T suppressor cells. J Immunol 2006; 176:2790-2798.
    • (2006) J Immunol , vol.176 , pp. 2790-2798
    • Kim-Schulze, S.1    Scotto, L.2    Vlad, G.3
  • 71
    • 48249118843 scopus 로고    scopus 로고
    • Immunoglobulin-like transcript 3-Fc suppresses T-cell responses to allogeneic human islet transplants in hu-NOD/SCID mice
    • Vlad G, D'Agati VD, Zhang QY, et al. Immunoglobulin-like transcript 3-Fc suppresses T-cell responses to allogeneic human islet transplants in hu-NOD/SCID mice. Diabetes 2008; 57:1878-1886.
    • (2008) Diabetes , vol.57 , pp. 1878-1886
    • Vlad, G.1    D'Agati, V.D.2    Zhang, Q.Y.3
  • 72
    • 68749092037 scopus 로고    scopus 로고
    • Suppression of xenogeneic graft-versus-host disease by treatment with immunoglobulin-like transcript 3-Fc
    • Vlad G, Stokes MB, Liu Z, et al. Suppression of xenogeneic graft-versus-host disease by treatment with immunoglobulin-like transcript 3-Fc. Hum Immunol 2009; 70:663-669.
    • (2009) Hum Immunol , vol.70 , pp. 663-669
    • Vlad, G.1    Stokes, M.B.2    Liu, Z.3
  • 73
    • 77952468729 scopus 로고    scopus 로고
    • Membraneand soluble ILT3arecritical to thegeneration ofTsuppressorcellsand induction of immunologi caltolerance
    • Vlad G, Chang CC, Colovai AI, et al. Membraneand soluble ILT3arecritical to thegeneration ofTsuppressorcellsand induction of immunologi caltolerance. Int Rev Immunol 2010; 29:119-132.
    • (2010) Int Rev Immunol , vol.29 , pp. 119-132
    • Vlad, G.1    Chang, C.C.2    Colovai, A.I.3
  • 74
    • 57649084981 scopus 로고    scopus 로고
    • CD8+ suppressor and cytotoxic T cells recognize the same human leukocyte antigen-A2 restricted cytomegalovirus peptide
    • Qin H, Vlad G, Cortesini R, et al. CD8+ suppressor and cytotoxic T cells recognize the same human leukocyte antigen-A2 restricted cytomegalovirus peptide. Hum Immunol 2008; 69:776-780.
    • (2008) Hum Immunol , vol.69 , pp. 776-780
    • Qin, H.1    Vlad, G.2    Cortesini, R.3
  • 76
    • 77951882989 scopus 로고    scopus 로고
    • Reversal of autoimmunity by boosting memory-like autoregulatory T cells
    • Tsai S, Shameli A, Yamanouchi J, et al. Reversal of autoimmunity by boosting memory-like autoregulatory T cells. Immunity 2010; 32:568-580.
    • (2010) Immunity , vol.32 , pp. 568-580
    • Tsai, S.1    Shameli, A.2    Yamanouchi, J.3
  • 77
    • 77952686356 scopus 로고    scopus 로고
    • In situ recognition of autoantigen as an essential gatekeeper in autoimmune CD8+ T cell inflammation
    • Wang J, Tsai S, Shameli A, et al. In situ recognition of autoantigen as an essential gatekeeper in autoimmune CD8+ T cell inflammation. Proc Natl Acad Sci USA 2010; 107:9317-9322.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 9317-9322
    • Wang, J.1    Tsai, S.2    Shameli, A.3
  • 78
    • 77951999656 scopus 로고    scopus 로고
    • + regulatoryTcells: Therapyfortype 1 diabetes?
    • + regulatoryTcells: therapyfortype 1 diabetes? Immunity 2010; 32:504-506.
    • (2010) Immunity , vol.32 , pp. 504-506
    • Zaccone, P.1    Cooke, A.2
  • 79
    • 65549127618 scopus 로고    scopus 로고
    • Human T regulatory cell therapy: Takea billion or so and call me in the morning
    • Riley J L, June CH, Blazar B R. Human T regulatory cell therapy: takea billion or so and call me in the morning. Immunity 2009; 30:656-665.
    • (2009) Immunity , vol.30 , pp. 656-665
    • Riley, J.L.1    Ch, J.2    Blazar, B.R.3
  • 80
    • 72949107091 scopus 로고    scopus 로고
    • Regulatory T cells in transplantation: Transferring mouse studies to the clinic
    • Long E, Wood KJ. Regulatory T cells in transplantation: transferring mouse studies to the clinic. Transplantation 2009; 88:1050-1056.
    • (2009) Transplantation , vol.88 , pp. 1050-1056
    • Long, E.1    Wood, K.J.2


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