Stimulation of β2-adrenergic receptors inhibits calcineurin activity in CD4+ T cells via PKA-AKAP interaction

Brain, Behavior, and Immunity

Volumn 25, Issue 1, 2011, Pages 59-66

  Riether, Carsten ^a   Kavelaars, Annemieke ^b   Wirth, Timo ^c   Pacheco López, Gustavo ^a   Doenlen, Raphael ^a   Willemen, Hanneke ^b   Heijnen, Cobi J ^b   Schedlowski, Manfred ^a,c   Engler, Harald ^a,c  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

A kinase anchoring protein; Adrenergic receptor; Calcineurin; Noradrenaline; Protein kinase A; Protein phosphatase 2B; Sympathetic nervous system; T cells

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; CALCINEURIN; CD3 ANTIBODY; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; GAMMA INTERFERON; INTERLEUKIN 2; NADOLOL; PEPTIDE; TERBUTALINE; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CD28 ANTIGEN; CD3 ANTIGEN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYTOKINE; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; ISOQUINOLINE DERIVATIVE; N (2 (4 BROMOCINNAMYLAMINO)ETHYL) 5 ISOQUINOLINESULFONAMIDE; N-(2-(4-BROMOCINNAMYLAMINO)ETHYL)-5-ISOQUINOLINESULFONAMIDE; PHOSPHATASE; PROTEIN KINASE INHIBITOR; SULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CELL FUNCTION; CELL PROLIFERATION; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME INHIBITION; GENE ACTIVATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; ANIMAL; BLOOD; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGY; KINETICS; METABOLISM; TH1 CELL;

A KINASE ANCHOR PROTEINS; ADRENERGIC BETA-2 RECEPTOR AGONISTS; ADRENERGIC BETA-AGONISTS; ANIMALS; ANTIGENS, CD28; ANTIGENS, CD3; CALCINEURIN; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOKINES; INDICATORS AND REAGENTS; ISOQUINOLINES; KINETICS; MALE; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN KINASE INHIBITORS; RATS; SULFONAMIDES; TERBUTALINE; TH1 CELLS;

EID: 78649318347     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2010.07.248     Document Type: Article

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