AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

Journal of Biological Chemistry

Volumn 273, Issue 42, 1998, Pages 27412-27419

  Kashishian, Adam ^a   Howard, Monique ^a   Loh, Christine ^a   Michael Gallatin, W ^a   Hoekstra, Merl F ^a   Lai, Yvonne ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; IMMUNOPHILIN; PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DEPHOSPHORYLATION; HUMAN; HUMAN CELL; KIDNEY CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN TARGETING;

BINDING SITES; CALCINEURIN; CARRIER PROTEINS; CLONING, MOLECULAR; DNA-BINDING PROTEINS; IMMUNOPHILINS; MODELS, MOLECULAR; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PEPTIDE FRAGMENTS; PHOSPHOPROTEIN PHOSPHATASE; PHOSPHOPROTEINS; PROTEIN BINDING; PROTEINS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

ANIMALIA;

EID: 0032538555     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.42.27412     Document Type: Article

References (51)

1. Krebs, E. G., and Beavo, J. A. (1979) Annu. Rev. Biochem. 48, 923-959
2. Hubbard, M. J., and Cohen, P. (1993) Trends Biochem. Sci. 18, 172-177
3. Mochly-Rosen, D. (1995) Science 268, 247-251
4. Pawson, T., and Scott, J. D. (1997) Science 278, 2075-2080
5. Egloff, M. P., Johnson, D. F., Moorhead, G., Cohen, P. T., Cohen, P., and Barford, D. (1997) EMBO J. 16, 1876-1887
6. Klee, C. B., Draeta, G. P., and Hubbard, M. J. (1988) Adv. Enzymol. Relat. Areas Mol. Biol. 61, 149-200
7. Yakel, J. L. (1997) Trends Pharmacol. Sci. 18, 124-134
8. Crabtree, G. R., and Clipstone, N. A. (1994) Annu. Rev. Biochem. 63, 1045-1083
9. Rao, A., Luo, C., and Hogan, P. G. (1997) Annu. Rev. Immunol. 15, 707-747
10. Huang, L. J., Durick, K., Weiner, J. A., Chun, J. and Taylor, S. S. (1997) J. Biol. Chem. 272, 8057-8064
11. Faux, M. C., and Scott, J. D. (1996) Cell. 85, 9-12
12. Dell'Acqua, M. L., and Scott, J. D. (1997) J. Biol. Chem. 272, 12881-12884
13. Dell'Acqua, M. L., Faux, M. C., Thorburn, J., Thorburn, A., and Scott, J. D. (1998) EMBO J. 17, 2246-2260
14. Carr, D. W., Hausken, Z. E., Fraser, I. D., Stofko-Hahn, R. E., and Scott, J. D. (1992) J. Biol. Chem. 267, 13376-13382
15. Coghlan, V. M., Perrino, B. A., Howard, M., Langeberg, L. K., Hicks, J. B., Gallatin, W. M., and Scott, J. D. (1995) Science 267, 108-111
16. Clipstone, N. A., and Crabtree, G. R. (1992) Nature 357, 695-697
17. Carr, D. W., Stofko-Hahn, R. E., Fraser, I. D., Cone, R. D., and Scott, J. D. (1992) J. Biol. Chem. 267, 16816-16823
18. McCaffrey, P. G., Luo, C., Kerppola, T. K., Jain, J., Badalian, T. M., Ho, A. M., Burgeon, E., Lane, W. S., Lambert, J. N., Curran, T., Verdine, G. L., Rao, A., and Hogan, P. G. (1993) Science 262, 750-754
19. Durfee, T., Becherer, K., Chen, P. L., Yeh, S. H., Yang, Y., Kilburn, A. E., Lee, W. H., and Elledge, S. J. (1993) Genes Dev. 7, 555-569
20. Kunkel, T. A. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 488-492
21. Kunkel, T. A., Roberts, J. D., and Zakour, R. A. (1987) Methods Enzymol. 154, 367-382
22. Perrino, B. A., Fong, Y. L., Brickey, D. A., Saitoh, Y., Ushio, Y., Fukunaga, K., Miyamoto, E., and Soderling, T. R. (1992) J. Biol. Chem. 267, 15965-15969
23. Clarke, P., Lin, H. C., and Wilcox, G. (1982) Gene (Amst.) 18, 157-163
24. Lin, H. C., Lei, S. P., and Wilcox, G. (1985) Gene (Amst.) 34, 123-128
25. Weber, W., Vogel, C. W., and Hilz, H. (1979) FEBS Lett. 99, 62-66
26. Harlow, E., and Lane, D. (1988) in Antibodies: A Laboratory Manual, pp. 593, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
27. Fruman, D. A., Klee, C. B., Bierer, B. E., and Burakoff, S. J. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 3686-3690
28. Sikkink, R., Haddy, A., MacKelvie, S., Mertz, P., Litwiller, R., and Rusnak, F. (1995) Biochemistry 34, 8348-8356
29. Kincaid, R. L., Nightingale, M. S., and Martin, B. M. (1988) Proc. Natl. Acad. Sci. U. S. A. 85, 8983-8987
30. Hashimoto, Y., Perrino, B. A., and Soderling, T. R. (1990) J. Biol. Chem. 265, 1924-1927
31. Milan, D., Griffith, J., Su, M., Price, E. R., and McKeon, F. (1994) Cell 79, 437-447
32. Flanagan, W. M., Corthesy, B., Bram, R. J., and Crabtree, G. R. (1991) Nature 352, 803-807
33. Northrop, J. P., Ullman, K. S., and Crabtree, G. R. (1993) J. Biol. Chem. 268, 2917-2923
34. Northrop, J. P., Ho, S. N., Chen, L., Thomas, D. J., Timmerman, L. A., Nolan, G. P., Admon, A., and Crabtree, G. R. (1994) Nature 369, 497-502
35. Negulescu, P. A., Shastri, N., and Cahalan, M. D. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 2873-2877
36. Nauert, J. B., Klauck, T. M., Langeberg, L. K., and Scott, J. D. (1997) Curr. Biol. 7, 52-61
37. Boise, L. H., Petryniak, B., Mao, X., June, C. H., Wang, C. Y., Lindsten, T., Bravo, R., Kovary, K., Leiden, J. M., and Thompson, C. B. (1993) Mol. Cell. Biol. 13, 1911-1919
38. Jain, J., McCaffrey, P. G., Valge-Archer, V. E., and Rao, A. (1992) Nature 356, 801-804
39. Faux, M. C., and Scott, J. D. (1997) J. Biol. Chem. 272, 17038-17044
40. Shaw, K. T., Ho, A. M., Raghavan, A., Kirn, J., Jain, J., Park, J., Sharma, S., Rao, A., and Hogan, P. G. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 11205-11209
41. Ruff, V. A., and Leach, K. L. (1995) J. Biol. Chem. 270, 22602-22607
42. Loh, C., Shaw, K. T., Carew, J., Viola, J. P., Luo, C., Perrino, B. A., and Rao, A. (1996) J. Biol. Chem. 271, 10884-10891
43. Klauck, T. M., Faux, M. C., Labudda, K., Langeberg, L. K., Jaken, S., and Scott, J. D. (1996) Science 271, 1589-1592
44. Kissinger, C. R., Parge, H. E., Knighton, D. R., Lewis, C. T., Pelletier, L. A., Tempczyk, A., Kalish, V. J., Tucker, K. D., Showalter, R. E., and Moomaw, E. W. (1995) Nature 378, 641-644
45. Griffith, J. P., Kim, J. L., Kim, E. E., Sintchak, M. D., Thomson, J. A., Fitzgibbon, M. J., Fleming, M. A., Caron, P. R., Hsiao, K., and Navia, M. A. (1995) Cell 82, 507-522
46. Feliciello, A., Li, Y., Avvedimento, E. V., Gottesman, M. E., and Rubin, C. S. (1997) Curr. Biol. 7, 1011-1014
47. Wesselborg, S., Fruman, D. A., Sagoo, J. K., Bierer, B. E., and Burakoff, S. J. (1996) J. Biol. Chem. 271, 1274-1277
48. Shibasaki, F., Kondo, E., Akagi, T., and McKeon, F. (1997) Nature 386, 728-731
49. Freund, T. F., Sik, A., Gulacsi, A., Katona, I., Lai, Y., Lockerbie, O., Scott, J. D., Gallatin, W. M., and Mody, I. (1997) Soc. Neurosci. Abstr. 2010
50. Sik, A., Hajos, N., Gulacsi, A., Mody, I., and Freund, T. F. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 3245-3250
51. Goldberg, J., Huang, H. B., Kwon, Y. G., Greengard, P., Nairn, A. C., and Kuriyan, J. (1995) Nature 376, 745-753