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Volumn 5, Issue 3, 2010, Pages 218-225

DNA vaccination in oncology: Current status, opportunities and perspectives

Author keywords

Adjuvants; Carriers; Dermal delivery; DNA vaccination; Tumor vaccination

Indexed keywords

ACID PHOSPHATASE PROSTATE ISOENZYME; CALRETICULIN; DNA VACCINE; GLYCOPROTEIN GP 100; GLYCOSAMINOGLYCAN; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEAT SHOCK PROTEIN 65; HEAT SHOCK PROTEIN 70; INTERLEUKIN 12; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MELAN A; MESSENGER RNA; MONOPHENOL MONOOXYGENASE; PLASMID VECTOR; PROSTATE SPECIFIC MEMBRANE ANTIGEN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

EID: 78649265589     PISSN: 15748847     EISSN: None     Source Type: Journal    
DOI: 10.2174/157488410791498734     Document Type: Article
Times cited : (5)

References (96)
  • 1
    • 60549117775 scopus 로고    scopus 로고
    • Activation of dendritic cells by toll-like receptors and C-type lectins
    • Diebold SS. Activation of dendritic cells by toll-like receptors and C-type lectins. Handb Exp Pharmacol 2009; 3-30
    • (2009) Handb Exp Pharmacol , pp. 3-30
    • Diebold, S.S.1
  • 2
    • 34548736008 scopus 로고    scopus 로고
    • Recent advances in antigen processing and presentation
    • Jensen PE. Recent advances in antigen processing and presentation. Nat Immunol 2007; 8: 1041-8
    • (2007) Nat Immunol , vol.8 , pp. 1041-1048
    • Jensen, P.E.1
  • 3
    • 50849144023 scopus 로고    scopus 로고
    • World wide experience with inactivated poliovirus vaccine
    • Bonnet MC, Dutta A. World wide experience with inactivated poliovirus vaccine. Vaccine 2008; 26: 4978-83
    • (2008) Vaccine , vol.26 , pp. 4978-4983
    • Bonnet, M.C.1    Dutta, A.2
  • 6
    • 34249942373 scopus 로고    scopus 로고
    • Production of clinical-grade plasmid DNA for human Phase I clinical trials and large animal clinical studies
    • Przybylowski M, Bartido S, Borquez-Ojeda O, Sadelain M, Riviere I. Production of clinical-grade plasmid DNA for human Phase I clinical trials and large animal clinical studies. Vaccine 2007; 25: 5013-24.
    • (2007) Vaccine , vol.25 , pp. 5013-5024
    • Przybylowski, M.1    Bartido, S.2    Borquez-Ojeda, O.3    Sadelain, M.4    Riviere, I.5
  • 7
    • 48749092592 scopus 로고    scopus 로고
    • The known unknowns of antigen processing and presentation
    • Vyas JM, Van der Veen AG, Ploegh HL. The known unknowns of antigen processing and presentation. Nat Rev Immunol 2008; 8: 607-18.
    • (2008) Nat Rev Immunol , vol.8 , pp. 607-618
    • Vyas, J.M.1    Van der Veen, A.G.2    Ploegh, H.L.3
  • 9
    • 0030820743 scopus 로고    scopus 로고
    • Priming of cytotoxic T lymphocytes by DNA vaccines: Requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes
    • Fu TM, Ulmer JB, Caulfield MJ, et al. Priming of cytotoxic T lymphocytes by DNA vaccines: requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes. Mol Med 1997; 3: 362-71.
    • (1997) Mol Med , vol.3 , pp. 362-371
    • Fu, T.M.1    Ulmer, J.B.2    Caulfield, M.J.3
  • 10
    • 0029789751 scopus 로고    scopus 로고
    • Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: Antigen presentation by nonmuscle cells
    • Ulmer JB, Deck RR, Dewitt CM, Donnhly JI, Liu MA. Generation of MHC class I-restricted cytotoxic T lymphocytes by expression of a viral protein in muscle cells: antigen presentation by nonmuscle cells. Immunology 1996; 89: 59-67.
    • (1996) Immunology , vol.89 , pp. 59-67
    • Ulmer, J.B.1    Deck, R.R.2    Dewitt, C.M.3    Donnhly, J.I.4    Liu, M.A.5
  • 11
    • 23944454145 scopus 로고    scopus 로고
    • Active antigen-specific immunotherapy of melanoma: From basic science to clinical investigation
    • Spagnoli GC, Adamina M, Bolli M, et al. Active antigen-specific immunotherapy of melanoma: from basic science to clinical investigation. World J Surg 2005; 29: 692-9.
    • (2005) World J Surg , vol.29 , pp. 692-699
    • Spagnoli, G.C.1    Adamina, M.2    Bolli, M.3
  • 12
    • 0025231388 scopus 로고
    • Direct gene transfer into mouse muscle in vivo
    • Wolff JA, Malone RW, Williams P, et al. Direct gene transfer into mouse muscle in vivo. Science 1990; 247: 1465-68.
    • (1990) Science , vol.247 , pp. 1465-1468
    • Wolff, J.A.1    Malone, R.W.2    Williams, P.3
  • 13
    • 0027411456 scopus 로고
    • Heterologous protection against influenza by injection of DNA encoding a viral protein
    • Ulmer JB, Donnelly JJ, Parker SE, et al. Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 1993; 259: 1745-9.
    • (1993) Science , vol.259 , pp. 1745-1749
    • Ulmer, J.B.1    Donnelly, J.J.2    Parker, S.E.3
  • 14
    • 0027284896 scopus 로고
    • Gene inoculation generates immune responses against human immunodeficiency virus type 1
    • Wang B, Ugen KE, Srikantan V, et al. Gene inoculation generates immune responses against human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1993; 90: 4156-60.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4156-4160
    • Wang, B.1    Ugen, K.E.2    Srikantan, V.3
  • 15
    • 0005457558 scopus 로고    scopus 로고
    • First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: Safety and host response
    • MacGregor RR, Boyer JD, Ugen KE, et al. First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response. J Infect Dis 1998; 178: 92-100.
    • (1998) J Infect Dis , vol.178 , pp. 92-100
    • Macgregor, R.R.1    Boyer, J.D.2    Ugen, K.E.3
  • 16
    • 58049200809 scopus 로고    scopus 로고
    • Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma
    • Daud AI, DeConti RC, Andrews S, et al. Phase I trial of interleukin-12 plasmid electroporation in patients with metastatic melanoma. J Clin Oncol. 2008; 26: 5896-903
    • (2008) J Clin Oncol , vol.26 , pp. 5896-5903
    • Daud, A.I.1    Deconti, R.C.2    Andrews, S.3
  • 17
    • 51449084228 scopus 로고    scopus 로고
    • Phase I trial of DNA-hsp65 immunotherapy for advanced squamous cell carcinoma of the head and neck
    • Michaluart P, Abdallah KA, Lima FD, et al. Phase I trial of DNA-hsp65 immunotherapy for advanced squamous cell carcinoma of the head and neck. Cancer Gene Ther 2008; 15: 676-84.
    • (2008) Cancer Gene Ther , vol.15 , pp. 676-684
    • Michaluart, P.1    Abdallah, K.A.2    Lima, F.D.3
  • 18
    • 31444446416 scopus 로고    scopus 로고
    • A combination of DNA vaccines targeting human papillomavirus type 16 E6 and E7 generates potent antitumor effects
    • Peng S, Tomson TT, Trimble C, et al. A combination of DNA vaccines targeting human papillomavirus type 16 E6 and E7 generates potent antitumor effects. Gene Ther 2006; 13: 257-65.
    • (2006) Gene Ther , vol.13 , pp. 257-265
    • Peng, S.1    Tomson, T.T.2    Trimble, C.3
  • 19
    • 0035844986 scopus 로고    scopus 로고
    • Optimization of transcriptional regulatory elements for constructing plasmid vectors
    • Xu ZL, Mizuguchi H, Ishii-Watabe A, et al. Optimization of transcriptional regulatory elements for constructing plasmid vectors. Gene 2001;272: 149-56.
    • (2001) Gene , vol.272 , pp. 149-156
    • Xu, Z.L.1    Mizuguchi, H.2    Ishii-Watabe, A.3
  • 20
    • 65549087977 scopus 로고    scopus 로고
    • Posttranscriptional regulatory elements enhance antigen expression and DNA vaccine efficacy
    • Sun J, Li D, Hao Y, et al. Posttranscriptional regulatory elements enhance antigen expression and DNA vaccine efficacy. DNA Cell Biol 2009; 28: 233-40.
    • (2009) DNA Cell Biol , vol.28 , pp. 233-240
    • Sun, J.1    Li, D.2    Hao, Y.3
  • 21
    • 0035077790 scopus 로고    scopus 로고
    • Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen
    • Hsu KF, Hung CF, Cheng WF, et al. Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen. Gene Ther 2001; 8: 376-83.
    • (2001) Gene Ther , vol.8 , pp. 376-383
    • Hsu, K.F.1    Hung, C.F.2    Cheng, W.F.3
  • 22
    • 0036784645 scopus 로고    scopus 로고
    • Critical components of a DNA fusion vaccine able to induce protective cytotoxic T cells against a single epitope of a tumor antigen
    • Rice J, Buchan S, Stevenson FK. Critical components of a DNA fusion vaccine able to induce protective cytotoxic T cells against a single epitope of a tumor antigen. J Immunol 2002; 169: 3908-13.
    • (2002) J Immunol , vol.169 , pp. 3908-3913
    • Rice, J.1    Buchan, S.2    Stevenson, F.K.3
  • 23
    • 12744263023 scopus 로고    scopus 로고
    • DNA vaccination against tumors
    • Prud'homme GJ. DNA vaccination against tumors. J Gene Med 2005; 7: 3-17.
    • (2005) J Gene Med , vol.7 , pp. 3-17
    • Prud'homme, G.J.1
  • 24
    • 28844459086 scopus 로고    scopus 로고
    • Enhancement of immunity by a DNA melanoma vaccine against TRP2 with CCL21 as an adjuvant
    • Yamano T, Kaneda Y, Huang S, Hiramatsu SH, Hoon DS. Enhancement of immunity by a DNA melanoma vaccine against TRP2 with CCL21 as an adjuvant. Mol Ther 2006; 13: 194-202.
    • (2006) Mol Ther , vol.13 , pp. 194-202
    • Yamano, T.1    Kaneda, Y.2    Huang, S.3    Hiramatsu, S.H.4    Hoon, D.S.5
  • 25
    • 49549106212 scopus 로고    scopus 로고
    • Comparative ability of various plasmid-based cytokines and chemokines to adjuvant the activity of HIV plasmid DNA vaccines
    • Xu R, Megati S, Roopchand V, et al. Comparative ability of various plasmid-based cytokines and chemokines to adjuvant the activity of HIV plasmid DNA vaccines. Vaccine 2008; 26: 4819-29.
    • (2008) Vaccine , vol.26 , pp. 4819-4829
    • Xu, R.1    Megati, S.2    Roopchand, V.3
  • 26
    • 0033990172 scopus 로고    scopus 로고
    • DNA vaccination of mice against rabies virus: Effects of the route of vaccination and the adjuvant monophosphoryl lipid A (MPL)
    • Lodmell DL, Ray NB, Ulrich JT, Ewalt LC, DNA vaccination of mice against rabies virus: effects of the route of vaccination and the adjuvant monophosphoryl lipid A (MPL), Vaccine 2000;18:1059-66.
    • (2000) Vaccine , vol.18 , pp. 1059-1066
    • Lodmell, D.L.1    Ray, N.B.2    Ulrich, J.T.3    Ewalt, L.C.4
  • 27
    • 32544451284 scopus 로고    scopus 로고
    • Topical imiquimod is a potent adjuvant to a weakly-immunogenic protein prototype vaccine
    • Johnston D, Bystryn JC. Topical imiquimod is a potent adjuvant to a weakly-immunogenic protein prototype vaccine. Vaccine 2006; 24: 1958-65.
    • (2006) Vaccine , vol.24 , pp. 1958-1965
    • Johnston, D.1    Bystryn, J.C.2
  • 28
    • 1842479742 scopus 로고    scopus 로고
    • Imiquimod and resiquimod in a mouse model: Adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery
    • Thomsen LL, Topley P, Daly MG, Brett SJ, Tite JP. Imiquimod and resiquimod in a mouse model: adjuvants for DNA vaccination by particle-mediated immunotherapeutic delivery. Vaccine 2004; 22: 1799-809.
    • (2004) Vaccine , vol.22 , pp. 1799-1809
    • Thomsen, L.L.1    Topley, P.2    Daly, M.G.3    Brett, S.J.4    Tite, J.P.5
  • 29
    • 18544362497 scopus 로고    scopus 로고
    • Effects of multiple copies of CpG on DNA vaccination
    • Zhang A, Jin H, Zhang F, et al. Effects of multiple copies of CpG on DNA vaccination. DNA Cell Biol 2005; 24: 292-8.
    • (2005) DNA Cell Biol , vol.24 , pp. 292-298
    • Zhang, A.1    Jin, H.2    Zhang, F.3
  • 31
    • 0034019945 scopus 로고    scopus 로고
    • Cationic polymer based gene delivery systems
    • De Smedt SC, Demeester J, Hennink WE. Cationic polymer based gene delivery systems. Pharm Res 2000; 17: 113-26.
    • (2000) Pharm Res , vol.17 , pp. 113-126
    • de Smedt, S.C.1    Demeester, J.2    Hennink, W.E.3
  • 32
    • 0347365764 scopus 로고    scopus 로고
    • An overview of current delivery systems in cancer gene therapy
    • El Aneed A. An overview of current delivery systems in cancer gene therapy. J Control Release 2004; 94: 1-14.
    • (2004) J Control Release , vol.94 , pp. 1-14
    • El Aneed, A.1
  • 33
    • 9244259077 scopus 로고    scopus 로고
    • DNA-loaded biodegradable microparticles as vaccine delivery systems and their interaction with dendritic cells
    • Jilek S, Merkle HP, Walter E. DNA-loaded biodegradable microparticles as vaccine delivery systems and their interaction with dendritic cells. Adv Drug Deliv Rev 2005; 57: 377-90.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 377-390
    • Jilek, S.1    Merkle, H.P.2    Walter, E.3
  • 35
    • 0029815814 scopus 로고    scopus 로고
    • Molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolisation
    • Crook K, McLachlan G, Stevenson BJ, Porteous DJ. Plasmid DNA molecules complexed with cationic liposomes are protected from degradation by nucleases and shearing by aerosolisation. Gene Ther 1996; 3: 834-9.
    • (1996) Gene Ther , vol.3 , pp. 834-839
    • Crook, K.1    McLachlan, G.2    Stevenson, B.J.3    Porteous, D.J.4    Plasmid, D.N.A.5
  • 36
    • 2442669391 scopus 로고    scopus 로고
    • Cross-linked microparticles as carriers for the delivery of plasmid DNA for vaccine development
    • Goh SL, Murthy N, Xu M, Frechet JM. Cross-linked microparticles as carriers for the delivery of plasmid DNA for vaccine development. Bioconjug Chem 2004; 15: 467-74.
    • (2004) Bioconjug Chem , vol.15 , pp. 467-474
    • Goh, S.L.1    Murthy, N.2    Xu, M.3    Frechet, J.M.4
  • 37
    • 0031739312 scopus 로고    scopus 로고
    • Enhanced gene expression in mouse lung by prolonging the retention time of intravenously injected plasmid DNA
    • Song YK, Liu F, Liu D. Enhanced gene expression in mouse lung by prolonging the retention time of intravenously injected plasmid DNA. Gene Ther 1998; 5: 1531-7.
    • (1998) Gene Ther , vol.5 , pp. 1531-1537
    • Song, Y.K.1    Liu, F.2    Liu, D.3
  • 38
    • 0028822228 scopus 로고
    • Systemic gene therapy: Biodistribution and long-term expression of a transgene in mice
    • Thierry AR, Lunardi-Iskandar Y, Bryant JL, et al. Systemic gene therapy: biodistribution and long-term expression of a transgene in mice. Proc Natl Acad Sci USA 1995; 92: 9742-6.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9742-9746
    • Thierry, A.R.1    Lunardi-Iskandar, Y.2    Bryant, J.L.3
  • 39
    • 1642575957 scopus 로고    scopus 로고
    • Size-dependent internalization of particles via the pathways of clathrin and caveolae mediated endocytosis
    • Rejman J, Oberle V, Zuhorn IS, Hoekstra D. Size-dependent internalization of particles via the pathways of clathrin and caveolae mediated endocytosis. Biochem J 2004; 377: 159-69.
    • (2004) Biochem J , vol.377 , pp. 159-169
    • Rejman, J.1    Oberle, V.2    Zuhorn, I.S.3    Hoekstra, D.4
  • 40
    • 34250867419 scopus 로고    scopus 로고
    • Cellular uptake of cationic polymer-DNA complexes via caveolae plays a pivotal role in gene transfection in COS-7 cells
    • van der Aa MA, Huth US, Hafele SY, et al. Cellular uptake of cationic polymer-DNA complexes via caveolae plays a pivotal role in gene transfection in COS-7 cells. Pharm Res 2007; 24: 1590-8.
    • (2007) Pharm Res , vol.24 , pp. 1590-1598
    • van der Aa, M.A.1    Huth, U.S.2    Hafele, S.Y.3
  • 41
    • 0029981092 scopus 로고    scopus 로고
    • Evidence for the role of proteoglycans in cation-mediated gene transfer
    • Mislick KA, Baldeschwieler JD. Evidence for the role of proteoglycans in cation-mediated gene transfer. Proc Natl Acad Sci USA 1996; 93: 12349-54.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12349-54
    • Mislick, K.A.1    Baldeschwieler, J.D.2
  • 42
    • 0035823546 scopus 로고    scopus 로고
    • Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes
    • Ruponen M, Ronkko S, Honkakoski P, et al. Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes. J Biol Chem 2001; 276: 33875-80.
    • (2001) J Biol Chem , vol.276 , pp. 33875-80
    • Ruponen, M.1    Ronkko, S.2    Honkakoski, P.3
  • 43
    • 5344263246 scopus 로고    scopus 로고
    • Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer
    • Ruponen M, Honkakoski P, Tammi M, Urtti A. Cell-surface glycosaminoglycans inhibit cation-mediated gene transfer. J Gene Med 2004; 6: 405-14.
    • (2004) J Gene Med , vol.6 , pp. 405-414
    • Ruponen, M.1    Honkakoski, P.2    Tammi, M.3    Urtti, A.4
  • 44
    • 72149108423 scopus 로고    scopus 로고
    • Shielding the cationic charge of nanoparticle-formulated dermal DNA vaccines is essential for antigen expression and immunogenicity
    • in press
    • van den Berg JH, Oosterhuis K, Hennink WE, et al. Shielding the cationic charge of nanoparticle-formulated dermal DNA vaccines is essential for antigen expression and immunogenicity, J Control Release 2009;in press.
    • (2009) J Control Release
    • van den Berg, J.H.1    Oosterhuis, K.2    Hennink, E.3
  • 45
    • 21344448185 scopus 로고    scopus 로고
    • Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model
    • Foged C, Brodin B, Frokjaer S, Sundblad A. Particle size and surface charge affect particle uptake by human dendritic cells in an in vitro model. Int J Pharm 2005; 298: 315-22.
    • (2005) Int J Pharm , vol.298 , pp. 315-322
    • Foged, C.1    Brodin, B.2    Frokjaer, S.3    Sundblad, A.4
  • 46
    • 3242682633 scopus 로고    scopus 로고
    • Composition and surface charge of DNA-loaded microparticles determine maturation and cytokine secretion in human dendritic cells
    • Jilek S, Ulrich M, Merkle HP, Walter E. Composition and surface charge of DNA-loaded microparticles determine maturation and cytokine secretion in human dendritic cells. Pharm Res 2004; 21: 1240-7.
    • (2004) Pharm Res , vol.21 , pp. 1240-1247
    • Jilek, S.1    Ulrich, M.2    Merkle, H.P.3    Walter, E.4
  • 47
    • 0023447252 scopus 로고
    • Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure
    • Felgner PL, Gadek TR, Holm M, et al. Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure. Proc Natl Acad Sci USA 1987; 84: 7413-7.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 7413-7417
    • Felgner, P.L.1    Gadek, T.R.2    Holm, M.3
  • 48
    • 8244245761 scopus 로고    scopus 로고
    • Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis
    • Porteous DJ, Dorin JR, McLachlan G, et al. Evidence for safety and efficacy of DOTAP cationic liposome mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Gene Ther 1997; 4: 210-8.
    • (1997) Gene Ther , vol.4 , pp. 210-218
    • Porteous, D.J.1    Dorin, J.R.2    McLachlan, G.3
  • 49
    • 0032886544 scopus 로고    scopus 로고
    • Immunotherapy of advanced malignancy by direct gene transfer of an interleukin-2 DNA/DMRIE/DOPE lipid complex: Phase I/II experience
    • Galanis E, Hersh EM, Stopeck AT, et al. Immunotherapy of advanced malignancy by direct gene transfer of an interleukin-2 DNA/DMRIE/DOPE lipid complex: phase I/II experience. J Clin Oncol 1999; 17: 3313-23.
    • (1999) J Clin Oncol , vol.17 , pp. 3313-3323
    • Galanis, E.1    Hersh, E.M.2    Stopeck, A.T.3
  • 51
    • 8544230612 scopus 로고    scopus 로고
    • Cationic compounds used in lipoplexes and polyplexes for gene delivery
    • Zhang S, Xu Y, Wang B, et al. Cationic compounds used in lipoplexes and polyplexes for gene delivery. J Control Release 2004; 100: 165-80.
    • (2004) J Control Release , vol.100 , pp. 165-180
    • Zhang, S.1    Xu, Y.2    Wang, B.3
  • 52
    • 0028075403 scopus 로고
    • Comparison of cell proliferation and toxicity assays using two cationic liposomes
    • Lappalainen K, Jaaskelainen I, Syrjanen K, Urtti A, Syrjanen S. Comparison of cell proliferation and toxicity assays using two cationic liposomes. Pharm Res 1994; 11: 1127-31.
    • (1994) Pharm Res , vol.11 , pp. 1127-1131
    • Lappalainen, K.1    Jaaskelainen, I.2    Syrjanen, K.3    Urtti, A.4    Syrjanen, S.5
  • 54
    • 0036401268 scopus 로고    scopus 로고
    • A nonionic amphiphile agent promotes gene delivery in vivo to skeletal and cardiac muscles
    • Pitard B, Pollard H, Agbulut O, et al. A nonionic amphiphile agent promotes gene delivery in vivo to skeletal and cardiac muscles. Hum Gene Ther 2002; 13: 1767-75.
    • (2002) Hum Gene Ther , vol.13 , pp. 1767-1775
    • Pitard, B.1    Pollard, H.2    Agbulut, O.3
  • 55
    • 16544377151 scopus 로고    scopus 로고
    • Negatively charged self-assembling DNA/poloxamine nanospheres for in vivo gene transfer
    • Pitard B, Bello-Roufai M, Lambert O, et al. Negatively charged self-assembling DNA/poloxamine nanospheres for in vivo gene transfer. Nucleic Acids Res 2004; 32: e159.
    • (2004) Nucleic Acids Res , vol.e159 , pp. 32
    • Pitard, B.1    Bello-Roufai, M.2    Lambert, O.3
  • 56
    • 33846539347 scopus 로고    scopus 로고
    • Optimization of cutaneous electrically mediated plasmid DNA delivery using novel electrode
    • Heller LC, Jaroszeski MJ, Coppola D, et al. Optimization of cutaneous electrically mediated plasmid DNA delivery using novel electrode. Gene Ther 2007; 14: 275-80.
    • (2007) Gene Ther , vol.14 , pp. 275-280
    • Heller, L.C.1    Jaroszeski, M.J.2    Coppola, D.3
  • 57
    • 16644382966 scopus 로고    scopus 로고
    • Epidermis-targeted gene transfer using in vivo electroporation
    • Maruyama H, Miyazaki J, Gejyo F. Epidermis-targeted gene transfer using in vivo electroporation. Methods Mol Biol 2005; 289: 431-6.
    • (2005) Methods Mol Biol , vol.289 , pp. 431-436
    • Maruyama, H.1    Miyazaki, J.2    Gejyo, F.3
  • 58
    • 33846859783 scopus 로고    scopus 로고
    • Electric pulses applied prior to intramuscular DNA vaccination greatly improve the vaccine immunogenicity
    • Peng B, Zhao Y, Xu L, Xu Y. Electric pulses applied prior to intramuscular DNA vaccination greatly improve the vaccine immunogenicity. Vaccine 2007; 25: 2064-73.
    • (2007) Vaccine , vol.25 , pp. 2064-2073
    • Peng, B.1    Zhao, Y.2    Xu, L.3    Xu, Y.4
  • 59
    • 30344433748 scopus 로고    scopus 로고
    • Enhancement of cellular immune response to a prostate cancer DNA vaccine by intradermal electroporation
    • Roos AK, Moreno S, Leder C et al. Enhancement of cellular immune response to a prostate cancer DNA vaccine by intradermal electroporation. Mol Ther 2006; 13: 320-7.
    • (2006) Mol Ther , vol.13 , pp. 320-327
    • Roos, A.K.1    Moreno, S.2    Leder, C.3
  • 60
    • 0032032220 scopus 로고    scopus 로고
    • Contribution of cells at the site of DNA vaccination to the generation of antigen-specific immunity and memory
    • Klinman DM, Sechler JM, Conover J, Gu M, Rosenberg AS. Contribution of cells at the site of DNA vaccination to the generation of antigen-specific immunity and memory. J Immunol 1998; 160: 2388-92.
    • (1998) J Immunol , vol.160 , pp. 2388-2392
    • Klinman, D.M.1    Sechler, J.M.2    Conover, J.3    Gu, M.4    Rosenberg, A.S.5
  • 61
    • 27944481229 scopus 로고    scopus 로고
    • Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2
    • Steitz J, Britten CM, Wolfel T, Tuting T. Effective induction of anti-melanoma immunity following genetic vaccination with synthetic mRNA coding for the fusion protein EGFP.TRP2. Cancer Immunol Immunother 2006; 55: 246-53.
    • (2006) Cancer Immunol Immunother , vol.55 , pp. 246-253
    • Steitz, J.1    Britten, C.M.2    Wolfel, T.3    Tuting, T.4
  • 62
    • 28544449584 scopus 로고    scopus 로고
    • Immunization without needles
    • Mitragotri S. Immunization without needles. Nat Rev Immunol 2005; 5: 905-16.
    • (2005) Nat Rev Immunol , vol.5 , pp. 905-916
    • Mitragotri, S.1
  • 63
    • 32044459282 scopus 로고    scopus 로고
    • Field trials of a very potent rabies DNA vaccine which induced long lasting virus neutralizing antibodies and protection in dogs in experimental conditions
    • Bahloul C, Taieb D, Diouani MF, et al. Field trials of a very potent rabies DNA vaccine which induced long lasting virus neutralizing antibodies and protection in dogs in experimental conditions. Vaccine 2006; 24: 1063-72.
    • (2006) Vaccine , vol.24 , pp. 1063-1072
    • Bahloul, C.1    Taieb, D.2    Diouani, M.F.3
  • 64
    • 78649300531 scopus 로고    scopus 로고
    • Augmented humoral and cellular immune response of hepatitis B virus DNA vaccine by micro-needle vaccination using Flt3L as an adjuvant
    • Zhou Q, Wang F, Yang F, et al. Augmented humoral and cellular immune response of hepatitis B virus DNA vaccine by micro-needle vaccination using Flt3L as an adjuvant. Vaccine 2009.
    • (2009) Vaccine
    • Zhou, Q.1    Wang, F.2    Yang, F.3
  • 65
    • 23844528774 scopus 로고    scopus 로고
    • A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression
    • Bins AD, Jorritsma A, Wolkers MC, et al. A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression. Nat Med 2005; 11: 899-904
    • (2005) Nat Med , vol.11 , pp. 899-904
    • Bins, A.D.1    Jorritsma, A.2    Wolkers, M.C.3
  • 66
    • 5444270495 scopus 로고    scopus 로고
    • DNA electrotransfer: Its principles and an updated review of its therapeutic applications
    • Andre F, Mir LM, DNA electrotransfer: its principles and an updated review of its therapeutic applications, Gene Ther 2004;11 Suppl 1:S33-S42.
    • (2004) Gene Ther , vol.11 , Issue.SUPPL. 1
    • Andre, F.1    Mir, L.M.2
  • 67
    • 0032127362 scopus 로고    scopus 로고
    • Treatment of cutaneous and subcutaneous tumors with electrochemotherapy using intralesional bleomycin
    • Heller R, Jaroszeski MJ, Reintgen DS, et al. Treatment of cutaneous and subcutaneous tumors with electrochemotherapy using intralesional bleomycin. Cancer 1998; 83: 148-57.
    • (1998) Cancer , vol.83 , pp. 148-157
    • Heller, R.1    Jaroszeski, M.J.2    Reintgen, D.S.3
  • 68
    • 33745135437 scopus 로고    scopus 로고
    • Preclinical safety assessment of a DNA vaccine using particle-mediated epidermal delivery in domestic pig, minipig and mouse
    • Dincer Z, Jones S, Haworth R. Preclinical safety assessment of a DNA vaccine using particle-mediated epidermal delivery in domestic pig, minipig and mouse. Exp Toxicol Pathol 2006; 57: 351-7.
    • (2006) Exp Toxicol Pathol , vol.57 , pp. 351-357
    • Dincer, Z.1    Jones, S.2    Haworth, R.3
  • 69
    • 0037402631 scopus 로고    scopus 로고
    • DNA immunization via intra-muscular and intradermal routes using a gene gun provides different magnitudes and durations on immune response
    • Ito K, Ito K, Shinohara N, Kato S. DNA immunization via intra-muscular and intradermal routes using a gene gun provides different magnitudes and durations on immune response. Mol Immunol 2003; 39: 847-54.
    • (2003) Mol Immunol , vol.39 , pp. 847-854
    • Ito, K.1    Ito, K.2    Shinohara, N.3    Kato, S.4
  • 70
    • 62949237235 scopus 로고    scopus 로고
    • DNA vaccination protects against an influenza challenge in a double-blind randomised placebocontrolled phase 1b clinical trial
    • Jones S, Evans K, McElwaine-Johnn H, et al. DNA vaccination protects against an influenza challenge in a double-blind randomised placebocontrolled phase 1b clinical trial. Vaccine 2009; 27: 2506-12.
    • (2009) Vaccine , vol.27 , pp. 2506-2512
    • Jones, S.1    Evans, K.2    McElwaine-Johnn, H.3
  • 71
    • 1342330352 scopus 로고    scopus 로고
    • Delivery of DNA to skin by particle bombardment
    • Wang S, Joshi S, Lu S. Delivery of DNA to skin by particle bombardment. Methods Mol Biol 2004; 245: 185-96.
    • (2004) Methods Mol Biol , vol.245 , pp. 185-196
    • Wang, S.1    Joshi, S.2    Lu, S.3
  • 72
    • 62549097258 scopus 로고    scopus 로고
    • Optimization of intradermal vaccination by DNA tattooing in human skin
    • van den Berg JH, Nujien B, Beijnen JH, et al. Optimization of intradermal vaccination by DNA tattooing in human skin. Hum Gene Ther 2009; 20: 181-9.
    • (2009) Hum Gene Ther , vol.20 , pp. 181-189
    • van den Berg, J.H.1    Nujien, B.2    Beijnen, J.H.3
  • 73
    • 44749092989 scopus 로고    scopus 로고
    • Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates
    • Verstrepen BE, Bins AD, Rollier CS, et al. Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates. Vaccine 2008; 26: 3346-51.
    • (2008) Vaccine , vol.26 , pp. 3346-3351
    • Verstrepen, B.E.1    Bins, A.D.2    Rollier, C.S.3
  • 74
    • 69949187556 scopus 로고    scopus 로고
    • DNA tattoo vaccination: Effect on plasmid purity and transfection efficiency of different topoisoforms
    • Quaak SG, van den Berg JH, Oosterhuis K, et al. DNA tattoo vaccination: effect on plasmid purity and transfection efficiency of different topoisoforms. J Control Release 2009; 139: 153-9.
    • (2009) J Control Release , vol.139 , pp. 153-159
    • Quaak, S.G.1    van den Berg, J.H.2    Oosterhuis, K.3
  • 75
    • 15944410592 scopus 로고    scopus 로고
    • Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide
    • Lutsiak ME, Semnani RT, De Pascalis R, et al. Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood 2005; 105: 2862-8.
    • (2005) Blood , vol.105 , pp. 2862-2868
    • Lutsiak, M.E.1    Semnani, R.T.2    de Pascalis, R.3
  • 76
    • 70449334144 scopus 로고    scopus 로고
    • Treg suppress CTL responses upon immunization with HSP gp96
    • Liu Z, Li X, Qiu L, et al. Treg suppress CTL responses upon immunization with HSP gp96. Eur J Immunol 2009; 39: 3110-20.
    • (2009) Eur J Immunol , vol.39 , pp. 3110-3120
    • Liu, Z.1    Li, X.2    Qiu, L.3
  • 77
    • 33748750051 scopus 로고    scopus 로고
    • Cancer immunosuppression and autoimmune disease: Beyond immunosuppressive networks for tumour immunity
    • Kim R, Emi M, Tanabe K. Cancer immunosuppression and autoimmune disease: beyond immunosuppressive networks for tumour immunity. Immunology 2006; 119: 254-64.
    • (2006) Immunology , vol.119 , pp. 254-264
    • Kim, R.1    Emi, M.2    Tanabe, K.3
  • 79
    • 54849418903 scopus 로고    scopus 로고
    • IDO1 and IDO2 are expressed in human tumors: Levo but not dextro-1-methyl tryptophan inhibits tryptophan catabolism
    • Lob S, Konigsrainer A, Zieker D, et al. IDO1 and IDO2 are expressed in human tumors: levo but not dextro-1-methyl tryptophan inhibits tryptophan catabolism. Cancer Immunol Immunother 2009; 58: 153-7.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 153-157
    • Lob, S.1    Konigsrainer, A.2    Zieker, D.3
  • 80
    • 0036299371 scopus 로고    scopus 로고
    • Anatomy, histology and immunohistochemistry of normal human skin
    • Kanitakis J. Anatomy, histology and immunohistochemistry of normal human skin. Eur J Dermatol 2002; 12: 390-9.
    • (2002) Eur J Dermatol , vol.12 , pp. 390-399
    • Kanitakis, J.1
  • 81
    • 76349088726 scopus 로고    scopus 로고
    • Epider mal injury and infection during poxvirus immunization is crucial for the generation of highly protective T cell-mediated immunity
    • Liu L, Zhong Q, Tian T, Dubin K, Athale SK, Kupper TS. Epider mal injury and infection during poxvirus immunization is crucial for the generation of highly protective T cell-mediated immunity. Nat Med 2010; 16(2): 224-7.
    • (2010) Nat Med , vol.16 , Issue.2 , pp. 224-227
    • Liu, L.1    Zhong, Q.2    Tian, T.3    Dubin, K.4    Athale, S.K.5    Kupper, T.S.6
  • 82
    • 3242715752 scopus 로고    scopus 로고
    • On the role of melanomaspecific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients
    • van Oijen M, Bins A, Elias S, et al. On the role of melanomaspecific CD8+ T-cell immunity in disease progression of advanced-stage melanoma patients. Clin Cancer Res 2004; 10: 4754-60.
    • (2004) Clin Cancer Res , vol.10 , pp. 4754-4760
    • van Oijen, M.1    Bins, A.2    Elias, S.3
  • 83
    • 33847401888 scopus 로고    scopus 로고
    • Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: An update on implications for chronic infections and tumor evasion
    • Blank C, Mackensen A. Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion. Cancer Immunol Immunother 2007; 56: 739-45.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 739-745
    • Blank, C.1    Mackensen, A.2
  • 84
    • 0036812718 scopus 로고    scopus 로고
    • Antigens derived from melanocyte differentiation proteins: Self-tolerance, autoimmunity, and use for cancer immunotherapy
    • Engelhard VH, Bullock TN, Colella TA, Sheasley SL, Mullins DW. Antigens derived from melanocyte differentiation proteins: self-tolerance, autoimmunity, and use for cancer immunotherapy. Immunol Rev 2002; 188: 136-46.
    • (2002) Immunol Rev , vol.188 , pp. 136-146
    • Engelhard, V.H.1    Bullock, T.N.2    Colella, T.A.3    Sheasley, S.L.4    Mullins, D.W.5
  • 85
    • 74049160009 scopus 로고    scopus 로고
    • Mechanisms maintaining peripheral tolerance
    • Mueller DL. Mechanisms maintaining peripheral tolerance. Nat Immunol 2010; 11: 21-7.
    • (2010) Nat Immunol , vol.11 , pp. 21-27
    • Mueller, D.L.1
  • 86
    • 67349274372 scopus 로고    scopus 로고
    • Prostate stem cell antigen DNA vaccination breaks tolerance to self antigen and inhibits prostate cancer growth
    • Ahmad S, Casey G, Sweeney P, Tangney M, O'Sullivan GC. Prostate stem cell antigen DNA vaccination breaks tolerance to self antigen and inhibits prostate cancer growth, Mol Ther 2009; 17: 1101-8.
    • (2009) Mol Ther , vol.17 , pp. 1101-1108
    • Ahmad, S.1    Casey, G.2    Sweeney, P.3    Tangney, M.4    O'Sullivan, G.C.5
  • 87
    • 0023755297 scopus 로고
    • The human papillomaviruses. An overview
    • Howley PM, Schlegel R. The human papillomaviruses. An overview. Am J Med 1988; 85: 155-8.
    • (1988) Am J Med , vol.85 , pp. 155-158
    • Howley, P.M.1    Schlegel, R.2
  • 88
    • 70350772293 scopus 로고    scopus 로고
    • Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia
    • Kenter GG, Welters MJ, Valentijn AR, et al. Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. N Engl J Med 2009; 361: 1838-47.
    • (2009) N Engl J Med , vol.361 , pp. 1838-1847
    • Kenter, G.G.1    Welters, M.J.2    Valentijn, A.R.3
  • 89
    • 33846879410 scopus 로고    scopus 로고
    • A phase I study of immunization using particle-mediated epidermal delivery of genes for gp100 and GM-CSF into uninvolved skin of melanoma patients
    • Cassaday RD, Sondel PM, King DM, et al. A phase I study of immunization using particle-mediated epidermal delivery of genes for gp100 and GM-CSF into uninvolved skin of melanoma patients. Clin Cancer Res 2007; 13: 540-9.
    • (2007) Clin Cancer Res , vol.13 , pp. 540-549
    • Cassaday, R.D.1    Sondel, P.M.2    King, D.M.3
  • 90
    • 0038697491 scopus 로고    scopus 로고
    • Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen
    • Rosenberg SA, Yang JC, Sherry RM, et al. Inability to immunize patients with metastatic melanoma using plasmid DNA encoding the gp100 melanoma-melanocyte antigen. Hum Gene Ther 2003; 14: 709-14.
    • (2003) Hum Gene Ther , vol.14 , pp. 709-714
    • Rosenberg, S.A.1    Yang, J.C.2    Sherry, R.M.3
  • 91
    • 0037664871 scopus 로고    scopus 로고
    • Phase I study of intranodal delivery of a plasmid DNA vaccine for patients with Stage IV melanoma
    • Tagawa ST, Lee P, Snively J, et al. Phase I study of intranodal delivery of a plasmid DNA vaccine for patients with Stage IV melanoma. Cancer 2003; 98: 144-54.
    • (2003) Cancer , vol.98 , pp. 144-154
    • Tagawa, S.T.1    Lee, P.2    Snively, J.3
  • 92
    • 21844471782 scopus 로고    scopus 로고
    • Phase I study of a plasmid DNA vaccine encoding MART-1 in patients with resected melanoma at risk for relapse
    • Triozzi PL, Aldrich W, Allen KO, et al. Phase I study of a plasmid DNA vaccine encoding MART-1 in patients with resected melanoma at risk for relapse. J Immunother (1997) 2005; 28: 382-8.
    • (2005) J Immunother (1997) , vol.28 , pp. 382-388
    • Triozzi, P.L.1    Aldrich, W.2    Allen, K.O.3
  • 93
    • 4344672484 scopus 로고    scopus 로고
    • A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer
    • Pavlenko M, Roos AK, Lundqvist A, et al. A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer. Br J Cancer 2004; 91: 688-94.
    • (2004) Br J Cancer , vol.91 , pp. 688-694
    • Pavlenko, M.1    Roos, A.K.2    Lundqvist, A.3
  • 94
    • 70249126960 scopus 로고    scopus 로고
    • Safety and immunological efficacy of a DNA vaccine encoding prostatic acid phosphatase in patients with stage D0 prostate cancer
    • McNeel DG, Dunphy EJ, Davies JG, et al. Safety and immunological efficacy of a DNA vaccine encoding prostatic acid phosphatase in patients with stage D0 prostate cancer. J Clin Oncol 2009; 27: 4047-54.
    • (2009) J Clin Oncol , vol.27 , pp. 4047-4054
    • McNeel, D.G.1    Dunphy, E.J.2    Davies, J.G.3
  • 95
    • 70350128929 scopus 로고    scopus 로고
    • DNA vaccination with electroporation induces increased antibody responses in patients with prostate cancer
    • Low L, Mander A, McCann K, et al. DNA vaccination with electroporation induces increased antibody responses in patients with prostate cancer. Hum Gene Ther 2009; 20: 1269-78.
    • (2009) Hum Gene Ther , vol.20 , pp. 1269-1278
    • Low, L.1    Mander, A.2    McCann, K.3
  • 96
    • 58849087222 scopus 로고    scopus 로고
    • A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3
    • Trimble CL, Peng S, Kos F, et al. A phase I trial of a human papillomavirus DNA vaccine for HPV16+ cervical intraepithelial neoplasia 2/3. Clin Cancer Res 2009; 15: 361-7.
    • (2009) Clin Cancer Res , vol.15 , pp. 361-367
    • Trimble, C.L.1    Peng, S.2    Kos, F.3


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