Preclinical safety assessment of a DNA vaccine using particle-mediated epidermal delivery in domestic pig, minipig and mouse

Experimental and Toxicologic Pathology

Volumn 57, Issue 5-6, 2006, Pages 351-357

  Dincer, Zuhal ^a   Jones, Stewart ^a   Haworth, Richard ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

DNA vaccine; HIV; Minipig; Mouse; Pig; PMED

Indexed keywords

DNA VACCINE; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN DETECTION; ANTIGEN EXPRESSION; APPLICATION SITE INFLAMMATION; APPLICATION SITE NECROSIS; APPLICATION SITE REACTION; ARTICLE; CONTROLLED STUDY; DOMESTIC PIG; DRUG DELIVERY SYSTEM; DRUG SAFETY; DRUG TOLERABILITY; EPIDERMIS; EXPERIMENTAL MODEL; FEMALE; HISTOPATHOLOGY; HUMAN VERSUS ANIMAL COMPARISON; IMMUNOHISTOCHEMISTRY; IMMUNOTHERAPY; MALE; MINIPIG; MOUSE; NONHUMAN; PARTICLE MEDIATED EPIDERMAL DELIVERY SYSTEM; SKIN; SKIN INFLAMMATION; SKIN MANIFESTATION; SKIN TOXICITY; SPECIES COMPARISON; THICKNESS; TISSUE REGENERATION; TISSUE REPAIR; TOXICITY TESTING; VACCINATION REACTION;

ANIMALIA; SUS SCROFA DOMESTICA;

EID: 33745135437     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2006.03.014     Document Type: Article

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