-
1
-
-
1842839986
-
Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site
-
Agren, M., Kogerman, P., Kleman, M. I., Wessling, M. and Toftgard, R. (2004). Expression of the PTCH1 tumor suppressor gene is regulated by alternative promoters and a single functional Gli-binding site. Gene 330, 101-114.
-
(2004)
Gene
, vol.330
, pp. 101-114
-
-
Agren, M.1
Kogerman, P.2
Kleman, M.I.3
Wessling, M.4
Toftgard, R.5
-
2
-
-
0031587830
-
Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor
-
Aza-Blanc, P., Ramirez-Weber, F. A., Laget, M. P., Schwartz, C. and Kornberg, T. B. (1997). Proteolysis that is inhibited by hedgehog targets Cubitus interruptus protein to the nucleus and converts it to a repressor. Cell 89, 1043-1053.
-
(1997)
Cell
, vol.89
, pp. 1043-1053
-
-
Aza-Blanc, P.1
Ramirez-Weber, F.A.2
Laget, M.P.3
Schwartz, C.4
Kornberg, T.B.5
-
3
-
-
0033761448
-
Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities
-
Aza-Blanc, P., Lin, H. Y., Ruiz i Altaba, A. and Kornberg, T. B. (2000). Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities. Development 127, 4293-4301.
-
(2000)
Development
, vol.127
, pp. 4293-4301
-
-
Aza-Blanc, P.1
Lin, H.Y.2
Ruiz i Altaba, A.3
Kornberg, T.B.4
-
4
-
-
0035691773
-
Gli1 can rescue the in vivo function of Gli2
-
Bai, C. B. and Joyner, A. L. (2001). Gli1 can rescue the in vivo function of Gli2. Development 128, 5161-5172.
-
(2001)
Development
, vol.128
, pp. 5161-5172
-
-
Bai, C.B.1
Joyner, A.L.2
-
5
-
-
0036801765
-
Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway
-
Bai, C. B., Auerbach, W., Lee, J. S., Stephen, D. and Joyner, A. L. (2002). Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway. Development 129, 475347-475361.
-
(2002)
Development
, vol.129
, pp. 475347-475361
-
-
Bai, C.B.1
Auerbach, W.2
Lee, J.S.3
Stephen, D.4
Joyner, A.L.5
-
6
-
-
0347764480
-
All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3
-
Bai, C. B., Stephen, D. and Joyner, A. L. (2004). All mouse ventral spinal cord patterning by hedgehog is Gli dependent and involves an activator function of Gli3. Dev. Cell 6, 103-115.
-
(2004)
Dev. Cell
, vol.6
, pp. 103-115
-
-
Bai, C.B.1
Stephen, D.2
Joyner, A.L.3
-
7
-
-
0023139629
-
Neural cell adhesion molecule expression in Xenopus embryos
-
Balak, K., Jacobson, M., Sunshine, J. and Rutishauser, U. (1987). Neural cell adhesion molecule expression in Xenopus embryos. Dev. Biol. 119, 540-550.
-
(1987)
Dev. Biol.
, vol.119
, pp. 540-550
-
-
Balak, K.1
Jacobson, M.2
Sunshine, J.3
Rutishauser, U.4
-
8
-
-
0030478206
-
X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiation
-
Bellefroid, E. J., Bourguignon, C., Hollemann, T., Ma, Q., Anderson, D. J., Kintner, C. and Pieler, T. (1996). X-MyT1, a Xenopus C2HC-type zinc finger protein with a regulatory function in neuronal differentiation. Cell 87, 1191-1202.
-
(1996)
Cell
, vol.87
, pp. 1191-1202
-
-
Bellefroid, E.J.1
Bourguignon, C.2
Hollemann, T.3
Ma, Q.4
Anderson, D.J.5
Kintner, C.6
Pieler, T.7
-
9
-
-
16144368562
-
Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly
-
Belloni, E., Muenke, M., Roessler, E., Traverso, G., Siegel-Bartelt, J., Frumkin, A., Mitchell, H. F., Donis-Keller, H., Helms, C., Hing, A. V. et al. (1996). Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly. Nat. Genet. 14, 353-356.
-
(1996)
Nat. Genet.
, vol.14
, pp. 353-356
-
-
Belloni, E.1
Muenke, M.2
Roessler, E.3
Traverso, G.4
Siegel-Bartelt, J.5
Frumkin, A.6
Mitchell, H.F.7
Donis-Keller, H.8
Helms, C.9
Hing, A.V.10
-
10
-
-
0032507944
-
Gli/Zic factors pattern the neural plate by defining domains of cell differentiation
-
Brewster, R., Lee, J. and Ruiz i Altaba, A. (1998). Gli/Zic factors pattern the neural plate by defining domains of cell differentiation. Nature 393, 579-583.
-
(1998)
Nature
, vol.393
, pp. 579-583
-
-
Brewster, R.1
Lee, J.2
Ruiz i Altaba, A.3
-
11
-
-
0033748331
-
Gli2 functions in FGF signaling during antero-posterior patterning
-
Brewster, R., Mullor, J. L. and Ruiz i Altaba, A. (2000). Gli2 functions in FGF signaling during antero-posterior patterning. Development 127, 4395-4405.
-
(2000)
Development
, vol.127
, pp. 4395-4405
-
-
Brewster, R.1
Mullor, J.L.2
Ruiz i Altaba, A.3
-
12
-
-
0034640087
-
A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube
-
Briscoe, J., Pierani, A., Jessell, T. M. and Ericson, J. (2000). A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell 101, 435-445.
-
(2000)
Cell
, vol.101
, pp. 435-445
-
-
Briscoe, J.1
Pierani, A.2
Jessell, T.M.3
Ericson, J.4
-
13
-
-
3042756178
-
Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh
-
Chen, Y., Knezevic, V., Ervin, V., Hutson, R., Ward, Y. and Mackem, S. (2004). Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh. Development 131, 2339-2347.
-
(2004)
Development
, vol.131
, pp. 2339-2347
-
-
Chen, Y.1
Knezevic, V.2
Ervin, V.3
Hutson, R.4
Ward, Y.5
Mackem, S.6
-
14
-
-
0029777408
-
Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
-
Chiang, C., Litingtung, Y., Lee, E., Young, K. E., Corden, J. L., Westphal, H. and Beachy, P. A. (1996). Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383, 407-413.
-
(1996)
Nature
, vol.383
, pp. 407-413
-
-
Chiang, C.1
Litingtung, Y.2
Lee, E.3
Young, K.E.4
Corden, J.L.5
Westphal, H.6
Beachy, P.A.7
-
15
-
-
0028891463
-
Neural induction and neurogenesis in amphibian embryos
-
Chitnis, A. and Kintner, C. (1995). Neural induction and neurogenesis in amphibian embryos. Perspect. Dev. Neurobiol. 3, 3-15.
-
(1995)
Perspect. Dev. Neurobiol.
, vol.3
, pp. 3-15
-
-
Chitnis, A.1
Kintner, C.2
-
16
-
-
0030018563
-
Sensitivity of proneural genes to lateral inhibition affects the pattern of primary neurons in Xenopus embryos
-
Chitnis, A. and Kintner, C. (1996). Sensitivity of proneural genes to lateral inhibition affects the pattern of primary neurons in Xenopus embryos. Development 122, 2295-2301.
-
(1996)
Development
, vol.122
, pp. 2295-2301
-
-
Chitnis, A.1
Kintner, C.2
-
17
-
-
0029061491
-
Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta
-
Chitnis, A., Henrique, D., Lewis, J., Ish-Horowicz, D. and Kintner, C. (1995). Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature 375, 761-766.
-
(1995)
Nature
, vol.375
, pp. 761-766
-
-
Chitnis, A.1
Henrique, D.2
Lewis, J.3
Ish-Horowicz, D.4
Kintner, C.5
-
18
-
-
0030844141
-
Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours
-
Dahmane, N., Lee, J., Robins, P., Heller, P. and Ruiz i Altaba, A. (1997). Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours. Nature389, 876-881.
-
(1997)
Nature
, vol.389
, pp. 876-881
-
-
Dahmane, N.1
Lee, J.2
Robins, P.3
Heller, P.4
Ruiz i Altaba, A.5
-
19
-
-
0035691884
-
The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis
-
Dahmane, N., Sanchez, P., Gitton, Y., Palma, V., Sun, T., Beyna, M., Weiner, H. and Ruiz i Altaba, A. (2001). The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis. Development 128, 5201-5212.
-
(2001)
Development
, vol.128
, pp. 5201-5212
-
-
Dahmane, N.1
Sanchez, P.2
Gitton, Y.3
Palma, V.4
Sun, T.5
Beyna, M.6
Weiner, H.7
Ruiz i Altaba, A.8
-
20
-
-
0037112001
-
Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3
-
Dai, P., Shinagawa, T., Nomura, T., Harada, J., Kaul, S. C., Wadhwa, R., Khan, M. M., Akimaru, H., Sasaki, H., Colmenares, C. et al. (2002). Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3. Genes Dev. 16, 2843-2848.
-
(2002)
Genes Dev.
, vol.16
, pp. 2843-2848
-
-
Dai, P.1
Shinagawa, T.2
Nomura, T.3
Harada, J.4
Kaul, S.C.5
Wadhwa, R.6
Khan, M.M.7
Akimaru, H.8
Sasaki, H.9
Colmenares, C.10
-
21
-
-
0031855859
-
Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice
-
Ding, Q., Motoyama, J., Gasca, S., Mo, R., Sasaki, H., Rossant, J. and Hui, C. C. (1998). Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development 125, 2533-2543.
-
(1998)
Development
, vol.125
, pp. 2533-2543
-
-
Ding, Q.1
Motoyama, J.2
Gasca, S.3
Mo, R.4
Sasaki, H.5
Rossant, J.6
Hui, C.C.7
-
22
-
-
0033533714
-
Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1
-
Ding, Q., Fukami, S., Meng, X., Nishizaki, Y., Zhang, X., Sasaki, H., Dlugosz, A., Nakafuku, M. and Hui, C. (1999). Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr. Biol. 9, 1119-1122.
-
(1999)
Curr. Biol.
, vol.9
, pp. 1119-1122
-
-
Ding, Q.1
Fukami, S.2
Meng, X.3
Nishizaki, Y.4
Zhang, X.5
Sasaki, H.6
Dlugosz, A.7
Nakafuku, M.8
Hui, C.9
-
23
-
-
0038813753
-
Characterization of the physical interaction of Gli proteins with SUFU proteins
-
Dunaeva, M., Michelson, P., Kogerman, P. and Toftgard, R. (2003). Characterization of the physical interaction of Gli proteins with SUFU proteins. J. Biol. Chem. 278, 5116-5122.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5116-5122
-
-
Dunaeva, M.1
Michelson, P.2
Kogerman, P.3
Toftgard, R.4
-
24
-
-
0028099362
-
XASH genes promote neurogenesis in Xenopus embryos
-
Ferreiro, B., Kintner, C., Zimmerman, K., Anderson, D. and Harris, W. A. (1994). XASH genes promote neurogenesis in Xenopus embryos. Development 120, 3649-3655.
-
(1994)
Development
, vol.120
, pp. 3649-3655
-
-
Ferreiro, B.1
Kintner, C.2
Zimmerman, K.3
Anderson, D.4
Harris, W.A.5
-
25
-
-
0032710015
-
Association of retinoic acid and hedgehog signaling in Xenopus primary neurogenesis
-
Franco, P. G., Paganelli, A. R., Lopez, S. L. and Carrasco, A. E. (1999). Association of retinoic acid and hedgehog signaling in Xenopus primary neurogenesis. Development 126, 4257-4265.
-
(1999)
Development
, vol.126
, pp. 4257-4265
-
-
Franco, P.G.1
Paganelli, A.R.2
Lopez, S.L.3
Carrasco, A.E.4
-
26
-
-
0033915931
-
The homeodomain-containing gene Xdbx inhibits neuronal differentiation in the developing embryo
-
Gershon, A. A., Rudnick, J., Kalam, L. and Zimmerman, K. (2000). The homeodomain-containing gene Xdbx inhibits neuronal differentiation in the developing embryo. Development 127, 2945-2954.
-
(2000)
Development
, vol.127
, pp. 2945-2954
-
-
Gershon, A.A.1
Rudnick, J.2
Kalam, L.3
Zimmerman, K.4
-
27
-
-
0034029282
-
Distinct effects of XBF-1 in regulating the cellcycle inhibitor p27(XIC1) and imparting a neural fate
-
Hardcastle, Z. and Papalopulu, N. (2000). Distinct effects of XBF-1 in regulating the cellcycle inhibitor p27(XIC1) and imparting a neural fate. Development 127, 1303-1314.
-
(2000)
Development
, vol.127
, pp. 1303-1314
-
-
Hardcastle, Z.1
Papalopulu, N.2
-
28
-
-
0027478216
-
A mouse model of greig cephalopolysyndactyly syndrome: The extra-toes mutation contains an intragenic deletion of the Gli3 gene
-
Hui, C. C. and Joyner, A. L. (1993). A mouse model of greig cephalopolysyndactyly syndrome: the extra-toes mutation contains an intragenic deletion of the Gli3 gene. Nat. Genet. 3, 241-246.
-
(1993)
Nat. Genet.
, vol.3
, pp. 241-246
-
-
Hui, C.C.1
Joyner, A.L.2
-
29
-
-
0030795109
-
Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1
-
Hynes, M., Stone, D. M., Dowd, M., Pitts-Meek, S., Goddard, A., Gurney, A. and Rosenthal, A. (1997). Control of cell pattern in the neural tube by the zinc finger transcription factor and oncogene Gli-1. Neuron 19, 15-26.
-
(1997)
Neuron
, vol.19
, pp. 15-26
-
-
Hynes, M.1
Stone, D.M.2
Dowd, M.3
Pitts-Meek, S.4
Goddard, A.5
Gurney, A.6
Rosenthal, A.7
-
30
-
-
0014097059
-
Extra-toes: A new mutant gene causing multiple abnormalities in the mouse
-
Johnson, D. R. (1967). Extra-toes: a new mutant gene causing multiple abnormalities in the mouse. J. Embryol. Exp. Morphol. 17, 543-581.
-
(1967)
J. Embryol. Exp. Morphol.
, vol.17
, pp. 543-581
-
-
Johnson, D.R.1
-
31
-
-
0031469311
-
Gene structure and allelic expression assay of the human GL13 gene
-
Kang, S., Rosenberg, M., Ko, V. D. and Biesecker, L. G. (1997). Gene structure and allelic expression assay of the human GL13 gene. Hum. Genet. 101, 154-157.
-
(1997)
Hum. Genet.
, vol.101
, pp. 154-157
-
-
Kang, S.1
Rosenberg, M.2
Ko, V.D.3
Biesecker, L.G.4
-
32
-
-
0033558211
-
Comparative synteny cloning of zebrafish you-too: Mutations in the Hedgehog target gli2 affect ventral forebrain patterning
-
Karlstrom, R. O., Talbot, W. S. and Schier, A. F. (1999). Comparative synteny cloning of zebrafish you-too: mutations in the Hedgehog target gli2 affect ventral forebrain patterning. Genes Dev. 13, 388-393.
-
(1999)
Genes Dev.
, vol.13
, pp. 388-393
-
-
Karlstrom, R.O.1
Talbot, W.S.2
Schier, A.F.3
-
33
-
-
0012843926
-
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development
-
Karlstrom, R. O., Tyurina, O. V., Kawakami, A., Nishioka, N., Talbot, W. S., Sasaki, H. and Schier, A. F. (2003). Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development. Development 130, 1549-1564.
-
(2003)
Development
, vol.130
, pp. 1549-1564
-
-
Karlstrom, R.O.1
Tyurina, O.V.2
Kawakami, A.3
Nishioka, N.4
Talbot, W.S.5
Sasaki, H.6
Schier, A.F.7
-
34
-
-
0036469897
-
Neurogenesis in embryos and in adult neural stem cells
-
Kintner, C. (2002). Neurogenesis in embryos and in adult neural stem cells. J. Neurosci. 22, 639-643.
-
(2002)
J. Neurosci.
, vol.22
, pp. 639-643
-
-
Kintner, C.1
-
35
-
-
0035143455
-
Molecular cloning and expression analysis of the Hedgehog receptors XPtc1 and XSmo in Xenopus laevis
-
Koebernick, K., Hollemann, T. and Pieler, T. (2001). Molecular cloning and expression analysis of the Hedgehog receptors XPtc1 and XSmo in Xenopus laevis. Mech. Dev. 100, 303-308.
-
(2001)
Mech. Dev.
, vol.100
, pp. 303-308
-
-
Koebernick, K.1
Hollemann, T.2
Pieler, T.3
-
36
-
-
0033194243
-
Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1
-
Kogerman, P., Grimm, T., Kogerman, L., Krause, D., Unden, A. B., Sandstedt, B., Toftgard, R. and Zaphiropoulos, P. G. (1999). Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1. Nat. Cell. Biol. 1, 312-319.
-
(1999)
Nat. Cell. Biol.
, vol.1
, pp. 312-319
-
-
Kogerman, P.1
Grimm, T.2
Kogerman, L.3
Krause, D.4
Unden, A.B.5
Sandstedt, B.6
Toftgard, R.7
Zaphiropoulos, P.G.8
-
37
-
-
0035831529
-
Physical and functional interactions between Zic and Gli proteins
-
Koyabu, Y., Nakata, K., Mizugishi, K., Aruga, J. and Mikoshiba, K. (2001). Physical and functional interactions between Zic and Gli proteins. J. Biol. Chem. 276, 6889-6892.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 6889-6892
-
-
Koyabu, Y.1
Nakata, K.2
Mizugishi, K.3
Aruga, J.4
Mikoshiba, K.5
-
38
-
-
0037218819
-
Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo
-
Lai, K., Kaspar, B. K., Gage, F. H. and Schaffer, D. V. (2003). Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo. Nat. Neurosci. 6, 21-27.
-
(2003)
Nat. Neurosci.
, vol.6
, pp. 21-27
-
-
Lai, K.1
Kaspar, B.K.2
Gage, F.H.3
Schaffer, D.V.4
-
39
-
-
0029068316
-
Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein
-
Lee, J. E., Hollenberg, S. M., Snider, L., Turner, D. L., Lipnick, N. and Weintraub, H. (1995). Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 268, 544-836.
-
(1995)
Science
, vol.268
, pp. 544-836
-
-
Lee, J.E.1
Hollenberg, S.M.2
Snider, L.3
Turner, D.L.4
Lipnick, N.5
Weintraub, H.6
-
40
-
-
0030805592
-
Gli1 is a target of Sonic hedgehog that induces ventral neural tube development
-
Lee, J., Platt, K. A., Censullo, P. and Ruiz i Altaba, A. (1997). Gli1 is a target of Sonic hedgehog that induces ventral neural tube development. Development 124, 2537-2552.
-
(1997)
Development
, vol.124
, pp. 2537-2552
-
-
Lee, J.1
Platt, K.A.2
Censullo, P.3
Ruiz i Altaba, A.4
-
41
-
-
0033808256
-
Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3
-
Litingtung, Y. and Chiang, C. (2000). Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3. Nat. Neurosci. 3, 979-985.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 979-985
-
-
Litingtung, Y.1
Chiang, C.2
-
42
-
-
0344925879
-
Cloning and characterization of Xenopus Id4 reveals differing roles for Id genes
-
Liu, K. J. and Harland, R. M. (2003). Cloning and characterization of Xenopus Id4 reveals differing roles for Id genes. Dev. Biol. 264, 339-351.
-
(2003)
Dev. Biol.
, vol.264
, pp. 339-351
-
-
Liu, K.J.1
Harland, R.M.2
-
43
-
-
0031795912
-
Carboxy-terminally truncated Gli3 proteins associated with Smads
-
Lui, F., Massague, J. and Ruiz i Altaba, A. (1998). Carboxy-terminally truncated Gli3 proteins associated with Smads. Nat. Genet. 20, 325-326.
-
(1998)
Nat. Genet.
, vol.20
, pp. 325-326
-
-
Lui, F.1
Massague, J.2
Ruiz i Altaba, A.3
-
44
-
-
0003073157
-
Identification of neurogenin, a vertebrate neuronal determination gene
-
Ma, Q., Kintner, C. and Anderson, D. J. (1996). Identification of neurogenin, a vertebrate neuronal determination gene. Cell 87, 43-52.
-
(1996)
Cell
, vol.87
, pp. 43-52
-
-
Ma, Q.1
Kintner, C.2
Anderson, D.J.3
-
45
-
-
10744230965
-
Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches
-
Machold, R., Hayashi, S., Rutlin, M., Muzumdar, M. D., Nery, S., Corbin, J. G., Gritli-Linde, A., Dellovade, T., Porter, J. A., Rubin, L. L. et al. (2003). Sonic hedgehog is required for progenitor cell maintenance in telencephalic stem cell niches. Neuron 39, 937-950.
-
(2003)
Neuron
, vol.39
, pp. 937-950
-
-
Machold, R.1
Hayashi, S.2
Rutlin, M.3
Muzumdar, M.D.4
Nery, S.5
Corbin, J.G.6
Gritli-Linde, A.7
Dellovade, T.8
Porter, J.A.9
Rubin, L.L.10
-
46
-
-
0037144506
-
Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1
-
Mao, J., Maye, P., Kogerman, P., Tejedor, F. J., Toftgard, R., Xie, W., Wu, G. and Wu, D. (2002). Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1. J. Biol. Chem. 277, 35156-35161.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 35156-35161
-
-
Mao, J.1
Maye, P.2
Kogerman, P.3
Tejedor, F.J.4
Toftgard, R.5
Xie, W.6
Wu, G.7
Wu, D.8
-
47
-
-
0031679850
-
Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system
-
Matise, M. P., Epstein, D. J., Park, H. L., Platt, K. A. and Joyner, A. L. (1998). Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development 125, 2759-2770.
-
(1998)
Development
, vol.125
, pp. 2759-2770
-
-
Matise, M.P.1
Epstein, D.J.2
Park, H.L.3
Platt, K.A.4
Joyner, A.L.5
-
48
-
-
13944284208
-
Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation
-
McDermott, A., Gustafsson, M., Elsam, T., Hui, C.-C., Emerson, C. P. and Borycki, A.-G. (2005). Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation. Development 132, 345-357.
-
(2005)
Development
, vol.132
, pp. 345-357
-
-
McDermott, A.1
Gustafsson, M.2
Elsam, T.3
Hui, C.-C.4
Emerson, C.P.5
Borycki, A.-G.6
-
49
-
-
0035098013
-
An absolute requirement for Cubitus interruptus in Hedgehog signaling
-
Methot, N. and Basler, K. (2001). An absolute requirement for Cubitus interruptus in Hedgehog signaling. Development 128, 733-742.
-
(2001)
Development
, vol.128
, pp. 733-742
-
-
Methot, N.1
Basler, K.2
-
50
-
-
0037447892
-
The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord
-
Meyer, N. P. and Roelink, H. (2003). The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord. Dev. Biol. 257, 343-355.
-
(2003)
Dev. Biol.
, vol.257
, pp. 343-355
-
-
Meyer, N.P.1
Roelink, H.2
-
51
-
-
0035910569
-
Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins
-
Mizugishi, K., Aruga, J., Nakata, K. and Mikoshiba, K. (2001). Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins. J. Biol. Chem. 276, 2180-2188.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 2180-2188
-
-
Mizugishi, K.1
Aruga, J.2
Nakata, K.3
Mikoshiba, K.4
-
52
-
-
0035873922
-
Wnt signals are targets and mediators of Gli function
-
Mullor, J. L., Dahmane, N., Sun, T. and Ruiz i Altaba, A. (2001). Wnt signals are targets and mediators of Gli function. Curr. Biol. 11, 769-773.
-
(2001)
Curr. Biol.
, vol.11
, pp. 769-773
-
-
Mullor, J.L.1
Dahmane, N.2
Sun, T.3
Ruiz i Altaba, A.4
-
53
-
-
0032122429
-
Xenopus Zic family and its role in neural and neural crest development
-
Nakata, K., Nagai, T., Aruga, J. and Mikoshiba, K. (1998). Xenopus Zic family and its role in neural and neural crest development. Mech. Dev. 75, 43-51.
-
(1998)
Mech. Dev.
, vol.75
, pp. 43-51
-
-
Nakata, K.1
Nagai, T.2
Aruga, J.3
Mikoshiba, K.4
-
54
-
-
0842279815
-
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex
-
Palma, V. and Ruiz i Altaba, A. (2004). Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex. Development 131, 337-345.
-
(2004)
Development
, vol.131
, pp. 337-345
-
-
Palma, V.1
Ruiz i Altaba, A.2
-
55
-
-
13344282140
-
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain
-
Palma, V., Lim, D. A., Dahmane, N., Sanchez, P., Brionne, T. C., Herzberg, C. D., Gitton, Y., Carleton, A., Alvarez-Buylla, A. and Ruiz i Altaba, A. (2005). Sonic hedgehog controls stem cell behavior in the postnatal and adult brain. Development 132, 335-344.
-
(2005)
Development
, vol.132
, pp. 335-344
-
-
Palma, V.1
Lim, D.A.2
Dahmane, N.3
Sanchez, P.4
Brionne, T.C.5
Herzberg, C.D.6
Gitton, Y.7
Carleton, A.8
Alvarez-Buylla, A.9
Ruiz i Altaba, A.10
-
56
-
-
0034055649
-
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
-
Park, H. L., Bai, C., Platt, K. A., Matise, M. P., Beeghly, A., Hui, C. C., Nakashima, M. and Joyner, A. L. (2000). Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation. Development 127, 1593-1605.
-
(2000)
Development
, vol.127
, pp. 1593-1605
-
-
Park, H.L.1
Bai, C.2
Platt, K.A.3
Matise, M.P.4
Beeghly, A.5
Hui, C.C.6
Nakashima, M.7
Joyner, A.L.8
-
57
-
-
0027423758
-
Crystal structure of a five-finger GLI-DNA complex: New perspectives on zinc fingers
-
Pavletich, N. P. and Pabo, C. O. (1993). Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers. Science 261, 1701-1707.
-
(1993)
Science
, vol.261
, pp. 1701-1707
-
-
Pavletich, N.P.1
Pabo, C.O.2
-
58
-
-
0030707867
-
Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis
-
Penzel, R., Oschwald, R., Chen, Y., Tacke, L. and Grunz, H. (1997). Characterization and early embryonic expression of a neural specific transcription factor xSOX3 in Xenopus laevis. Int. J. Dev. Biol. 41, 667-677.
-
(1997)
Int. J. Dev. Biol.
, vol.41
, pp. 667-677
-
-
Penzel, R.1
Oschwald, R.2
Chen, Y.3
Tacke, L.4
Grunz, H.5
-
59
-
-
0037111829
-
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity
-
Persson, M., Stamataki, D., te Welscher, P., Andersson, E., Bose, J., Ruther, U., Ericson, J. and Briscoe, J. (2002). Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity. Genes Dev. 16, 2865-2878.
-
(2002)
Genes Dev.
, vol.16
, pp. 2865-2878
-
-
Persson, M.1
Stamataki, D.2
te Welscher, P.3
Andersson, E.4
Bose, J.5
Ruther, U.6
Ericson, J.7
Briscoe, J.8
-
60
-
-
0033603209
-
A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord
-
Pierani, A., Brenner-Morton, S., Chiang, C. and Jessell, T. M. (1999). A sonic hedgehog-independent, retinoid-activated pathway of neurogenesis in the ventral spinal cord. Cell 97, 903-915.
-
(1999)
Cell
, vol.97
, pp. 903-915
-
-
Pierani, A.1
Brenner-Morton, S.2
Chiang, C.3
Jessell, T.M.4
-
61
-
-
0031279063
-
Mutation in GLI3 in postaxial polydactyly type A
-
Radhakrishna, U., Wild, A., Grzeschik, K. H. and Antonarakis, S. E. (1997). Mutation in GLI3 in postaxial polydactyly type A. Nat. Genet. 17, 269-271.
-
(1997)
Nat. Genet.
, vol.17
, pp. 269-271
-
-
Radhakrishna, U.1
Wild, A.2
Grzeschik, K.H.3
Antonarakis, S.E.4
-
62
-
-
0030294408
-
Mutations in the human Sonic Hedgehog gene cause holoprosencephaly
-
Roessler, E., Belloni, E., Gaudenz, K., Jay, P., Berta, P., Scherer, S. W., Tsui, L. C. and Muenke, M. (1996). Mutations in the human Sonic Hedgehog gene cause holoprosencephaly. Nat. Genet. 14, 357-360.
-
(1996)
Nat. Genet.
, vol.14
, pp. 357-360
-
-
Roessler, E.1
Belloni, E.2
Gaudenz, K.3
Jay, P.4
Berta, P.5
Scherer, S.W.6
Tsui, L.C.7
Muenke, M.8
-
63
-
-
0344392285
-
Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features
-
Roessler, E., Du, Y. Z., Mullor, J. L., Casas, E., Allen, W. P., Gillessen-Kaesbach, G., Roeder, E. R., Ming, J. E., Ruiz i Altaba, A. and Muenke, M. (2003). Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features. Proc. Natl. Acad. Sci. USA 100, 13424-13429.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 13424-13429
-
-
Roessler, E.1
Du, Y.Z.2
Mullor, J.L.3
Casas, E.4
Allen, W.P.5
Gillessen-Kaesbach, G.6
Roeder, E.R.7
Ming, J.E.8
Ruiz i Altaba, A.9
Muenke, M.10
-
64
-
-
0001625080
-
Catching a Gli-mpse of Hedgehog
-
Ruiz i Altaba, A. (1997). Catching a Gli-mpse of Hedgehog. Cell 90, 193-196.
-
(1997)
Cell
, vol.90
, pp. 193-196
-
-
Ruiz i Altaba, A.1
-
65
-
-
0031820135
-
Combinatorial Gli gene function in floor plate and neuronal inductionsby Sonic hedgehog
-
Ruiz i Altaba, A. (1998). Combinatorial Gli gene function in floor plate and neuronal inductionsby Sonic hedgehog. Development 125, 2203-2212.
-
(1998)
Development
, vol.125
, pp. 2203-2212
-
-
Ruiz i Altaba, A.1
-
66
-
-
0032808138
-
Gli proteins encode context-dependent positive and negative functions: Implications for development and disease
-
Ruiz i Altaba, A. (1999). Gli proteins encode context-dependent positive and negative functions: implications for development and disease. Development 126, 3205-3216.
-
(1999)
Development
, vol.126
, pp. 3205-3216
-
-
Ruiz i Altaba, A.1
-
67
-
-
0025901042
-
Retinoic acid modifies the pattern of cell differentiation in the central nervous system of neurula stage Xenopus embryos
-
Ruiz i Altaba, A. and Jessell, T. M. (1991). Retinoic acid modifies the pattern of cell differentiation in the central nervous system of neurula stage Xenopus embryos. Development 112, 945-958.
-
(1991)
Development
, vol.112
, pp. 945-958
-
-
Ruiz i Altaba, A.1
Jessell, T.M.2
-
68
-
-
0026660722
-
Pintallavis, a gene expressed in the organizer andmidline cells of frog embryos: Involvement in the development of the neural axis
-
Ruiz i Altaba, A. and Jessell, T. M. (1992). Pintallavis, a gene expressed in the organizer andmidline cells of frog embryos: involvement in the development of the neural axis. Development 116, 81-93.
-
(1992)
Development
, vol.116
, pp. 81-93
-
-
Ruiz i Altaba, A.1
Jessell, T.M.2
-
69
-
-
0029010669
-
Restrictions to floor plate induction by hedgehog and winged-helix genes in the neural tube of frog embryos
-
Ruiz i Altaba, A., Jessell, T. M. and Roelink, H. (1995). Restrictions to floor plate induction by hedgehog and winged-helix genes in the neural tube of frog embryos. Mol. Cell. Neurosci. 6, 106-121.
-
(1995)
Mol. Cell. Neurosci.
, vol.6
, pp. 106-121
-
-
Ruiz i Altaba, A.1
Jessell, T.M.2
Roelink, H.3
-
70
-
-
0141673242
-
The emergent design of the neural tube: Prepattern, SHH morphogen and GLI code
-
Ruiz i Altaba, A., Nguyen, V. and Palma, V. (2003). The emergent design of the neural tube: prepattern, SHH morphogen and GLI code. Curr. Opin. Genet. Dev. 13, 513-521.
-
(2003)
Curr. Opin. Genet. Dev.
, vol.13
, pp. 513-521
-
-
Ruiz i Altaba, A.1
Nguyen, V.2
Palma, V.3
-
71
-
-
0842265834
-
Hedgehog-Gli signaling in brain tumors: Stem cells and paradevelopmental programs in cancer
-
Ruiz i Altaba, A., Stecca, B. and Sanchez, P. (2004). Hedgehog-Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer. Cancer Lett. 204, 145-157.
-
(2004)
Cancer Lett.
, vol.204
, pp. 145-157
-
-
Ruiz i Altaba, A.1
Stecca, B.2
Sanchez, P.3
-
72
-
-
4344659678
-
Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
-
Sanchez, P., Hernandez, A. M., Stecca, B., Kahler, A. J., DeGueme, A. M., Barrett, A., Beyna, M., Datta, M. W., Datta, S. and Ruiz i Altaba, A. (2004). Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling. Proc. Natl. Acad. Sci. USA 101, 12561-12566.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12561-12566
-
-
Sanchez, P.1
Hernandez, A.M.2
Stecca, B.3
Kahler, A.J.4
DeGueme, A.M.5
Barrett, A.6
Beyna, M.7
Datta, M.W.8
Datta, S.9
Ruiz i Altaba, A.10
-
73
-
-
0033993477
-
The control of Xenopus embryonic primary neurogenesis is mediated by retinoid signalling in the neurectoderm
-
Sharpe, C. and Goldstone, K. (2000). The control of Xenopus embryonic primary neurogenesis is mediated by retinoid signalling in the neurectoderm. Mech Dev. 91, 69-80.
-
(2000)
Mech. Dev.
, vol.91
, pp. 69-80
-
-
Sharpe, C.1
Goldstone, K.2
-
74
-
-
0026445646
-
Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt)
-
Schimmang, T., Lemaistre, M., Vortkamp, A. and Ruther, U. (1992). Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes (Xt). Development 116, 799-804.
-
(1992)
Development
, vol.116
, pp. 799-804
-
-
Schimmang, T.1
Lemaistre, M.2
Vortkamp, A.3
Ruther, U.4
-
75
-
-
0001466654
-
GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization
-
Shin, S. H., Kogerman, P., Lindstrom, E., Toftgard, R. and Biesecker, L. G. (1999). GLI3 mutations in human disorders mimic Drosophila cubitus interruptus protein functions and localization. Proc. Natl. Acad. Sci. USA 96, 2880-2884.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 2880-2884
-
-
Shin, S.H.1
Kogerman, P.2
Lindstrom, E.3
Toftgard, R.4
Biesecker, L.G.5
-
76
-
-
0034333512
-
Distinct expression of two types of Xenopus Patched genes during early embryogenesis and hindlimb development
-
Takabatake, T., Takahashi, T. C., Takabatake, Y., Yamada, K., Ogawa, M. and Takeshima, K. (2000). Distinct expression of two types of Xenopus Patched genes during early embryogenesis and hindlimb development. Mech. Dev. 98, 99-104.
-
(2000)
Mech. Dev.
, vol.98
, pp. 99-104
-
-
Takabatake, T.1
Takahashi, T.C.2
Takabatake, Y.3
Yamada, K.4
Ogawa, M.5
Takeshima, K.6
-
77
-
-
0242270878
-
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
-
Thayer, S. P., di Magliano, M. P., Heiser, P. W., Nielsen, C. M., Roberts, D. J., Lauwers, G. Y., Qi, Y. P., Gysin, S., Fernandez-del Castillo, C. and Yajnik, V. (2003). Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis. Nature 425, 851-856.
-
(2003)
Nature
, vol.425
, pp. 851-856
-
-
Thayer, S.P.1
di Magliano, M.P.2
Heiser, P.W.3
Nielsen, C.M.4
Roberts, D.J.5
Lauwers, G.Y.6
Qi, Y.P.7
Gysin, S.8
Fernandez-del Castillo, C.9
Yajnik, V.10
-
78
-
-
0032872508
-
Gli3 is required for Emx gene expression during dorsal telencephalon development
-
Theil, T., Alvarez-Bolado, G., Walter, A. and Ruther, U. (1999). Gli3 is required for Emx gene expression during dorsal telencephalon development. Development 126, 3561-3571.
-
(1999)
Development
, vol.126
, pp. 3561-3571
-
-
Theil, T.1
Alvarez-Bolado, G.2
Walter, A.3
Ruther, U.4
-
79
-
-
0034650621
-
Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes
-
Tole, S., Ragsdale, C. W. and Grove, E. A. (2000). Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes. J. Dev. Biol. 217, 254-265.
-
(2000)
J. Dev. Biol.
, vol.217
, pp. 254-265
-
-
Tole, S.1
Ragsdale, C.W.2
Grove, E.A.3
-
80
-
-
2642705879
-
A Xenopus homologue of aml-1 reveals unexpected patterning mechanisms leading to the formation of embryonic blood
-
Tracey, W. D., Pepling, M. E., Horb, M. E., Thomsen, G. H. and Gergen, J. P. (1998). A Xenopus homologue of aml-1 reveals unexpected patterning mechanisms leading to the formation of embryonic blood. Development 125, 1371-1380.
-
(1998)
Development
, vol.125
, pp. 1371-1380
-
-
Tracey, W.D.1
Pepling, M.E.2
Horb, M.E.3
Thomsen, G.H.4
Gergen, J.P.5
-
81
-
-
11144327100
-
Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling
-
Tyurina, O. V., Guner, B., Popova, E., Feng, J., Schier, A. F., Kohtz, J. D. and Karlstrom, R. O. (2005). Zebrafish Gli3 functions as both an activator and a repressor in Hedgehog signaling. Dev. Biol. 277, 537-556.
-
(2005)
Dev. Biol.
, vol.277
, pp. 537-556
-
-
Tyurina, O.V.1
Guner, B.2
Popova, E.3
Feng, J.4
Schier, A.F.5
Kohtz, J.D.6
Karlstrom, R.O.7
-
82
-
-
0033581926
-
Distinct and regulated activities of human Gli proteins in Drosophila
-
von Mering, C. and Basler, K. (1999). Distinct and regulated activities of human Gli proteins in Drosophila. Curr. Biol. 9, 1319-1322.
-
(1999)
Curr. Biol.
, vol.9
, pp. 1319-1322
-
-
von Mering, C.1
Basler, K.2
-
83
-
-
0025812172
-
GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families
-
Vortkamp, A., Gessler, M. and Grzeschik, K. H. (1991). GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families. Nature 352, 539-540.
-
(1991)
Nature
, vol.352
, pp. 539-540
-
-
Vortkamp, A.1
Gessler, M.2
Grzeschik, K.H.3
-
84
-
-
0034681266
-
Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb
-
Wang, B., Fallon, J. F. and Beachy, P. A. (2000). Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb. Cell 100, 423-434.
-
(2000)
Cell
, vol.100
, pp. 423-434
-
-
Wang, B.1
Fallon, J.F.2
Beachy, P.A.3
-
85
-
-
0242669237
-
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
-
Watkins, D. N., Berman, D. M., Burkholder, S. G., Wang, B., Beachy, P. A. and Baylin, S. B. (2003). Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 422, 313-317.
-
(2003)
Nature
, vol.422
, pp. 313-317
-
-
Watkins, D.N.1
Berman, D.M.2
Burkholder, S.G.3
Wang, B.4
Beachy, P.A.5
Baylin, S.B.6
-
86
-
-
0037112420
-
Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1
-
Weiner, H. L., Bakst, R., Hurlbert, M. S., Ruggiero, J., Ahn, E., Lee, W. S., Stephen, D., Zagzag, D., Joyner, A. L. and Turnbull, D. H. (2002). Induction of medulloblastomas in mice by sonic hedgehog, independent of Gli1. Cancer Res. 62, 6385-6389.
-
(2002)
Cancer Res.
, vol.62
, pp. 6385-6389
-
-
Weiner, H.L.1
Bakst, R.2
Hurlbert, M.S.3
Ruggiero, J.4
Ahn, E.5
Lee, W.S.6
Stephen, D.7
Zagzag, D.8
Joyner, A.L.9
Turnbull, D.H.10
-
87
-
-
0032589650
-
Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity
-
Zuñiga, A. and Zeller, R. (1999). Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity. Development 126, 13-21.
-
(1999)
Development
, vol.126
, pp. 13-21
-
-
Zuñiga, A.1
Zeller, R.2
-
88
-
-
2942694533
-
A dual role for Hox genes in limb anterior-posterior asymmetry
-
Zakany, J., Kmita, M. and Duboule, D. (2004). A dual role for Hox genes in limb anterior-posterior asymmetry. Science 304, 1669-1672.
-
(2004)
Science
, vol.304
, pp. 1669-1672
-
-
Zakany, J.1
Kmita, M.2
Duboule, D.3
|